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Volumn 16, Issue 6, 2011, Pages 896-903

Cutaneous melanoma in situ: Translational evidence from a large population-based study

Author keywords

Cutaneous melanoma; In situ; Incidence; Population study; Relative survival analysis; Risk; Treatment

Indexed keywords

ADULT; AGED; ARTICLE; CANCER INCIDENCE; CANCER INVASION; CANCER SURGERY; CANCER SURVIVAL; CUTANEOUS MELANOMA IN SITU; DIGESTIVE SYSTEM CANCER; FEMALE; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; MELANOMA; POPULATION RESEARCH; POPULATION SIZE; PRIORITY JOURNAL; RISK REDUCTION; SKIN SURGERY;

EID: 79959626752     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2010-0340     Document Type: Article
Times cited : (67)

References (64)
  • 1
    • 84857017872 scopus 로고    scopus 로고
    • Epidemiology of invasive cutaneous melanoma
    • MacKie RM, Hauschild A, Eggermont AM. Epidemiology of invasive cutaneous melanoma. Ann Oncol 2009;20 Suppl 6:vi1-vi7.
    • (2009) Ann Oncol , vol.20 , Issue.SUPPL. 6
    • Mackie, R.M.1    Hauschild, A.2    Eggermont, A.M.3
  • 2
    • 57449086541 scopus 로고    scopus 로고
    • Melanoma epidemiology and trends
    • Garbe C, Leiter U. Melanoma epidemiology and trends. Clin Dermatol 2009;27:3-9.
    • (2009) Clin Dermatol , vol.27 , pp. 3-9
    • Garbe, C.1    Leiter, U.2
  • 3
    • 55949120590 scopus 로고    scopus 로고
    • StatBite: Distribution of melanoma incidence and mortality by age, 2001- 2005
    • StatBite: Distribution of melanoma incidence and mortality by age, 2001- 2005. J Natl Cancer Inst 2008;100:1498.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1498
  • 5
  • 6
    • 77953421580 scopus 로고    scopus 로고
    • NCCN) Clinical Practice Guidelines in Oncology, Available at
    • NCCN. Melanoma. National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines in Oncology, 2009. Available at http://www.nccn.org/index.asp.
    • (2009) National Comprehensive Cancer Network
    • Melanoma, N.C.C.N.1
  • 7
    • 68149126262 scopus 로고    scopus 로고
    • Current systemic therapy for metastatic melanoma
    • Agarwala SS. Current systemic therapy for metastatic melanoma. Expert Rev Anticancer Ther 2009;9:587-595.
    • (2009) Expert Rev Anticancer Ther , vol.9 , pp. 587-595
    • Agarwala, S.S.1
  • 8
    • 0022179910 scopus 로고
    • Malignant melanoma in situ: The flat, curable stage of malignant melanoma
    • Ackerman AB. Malignant melanoma in situ: the flat, curable stage of malignant melanoma. Pathology 1985;17:298-300.
    • (1985) Pathology , vol.17 , pp. 298-300
    • Ackerman, A.B.1
  • 9
    • 0031985422 scopus 로고    scopus 로고
    • Problems with lesions related to the development of malignant melanoma: Common nevi, dysplastic nevi, malignant melanoma in situ, and radial growth phase malignant melanoma
    • Clark WH Jr., Tucker MA. Problems with lesions related to the development of malignant melanoma: common nevi, dysplastic nevi, malignant melanoma in situ, and radial growth phase malignant melanoma. Hum Pathol 1998;29:8-14.
    • (1998) Hum Pathol , vol.29 , pp. 8-14
    • Clark, W.H.1    Tucker, M.A.2
  • 11
    • 0025678354 scopus 로고
    • Malignant melanoma in situ
    • Clark WH Jr. Malignant melanoma in situ. Hum Pathol 1990;21:1197-1198.
    • (1990) Hum Pathol , vol.21 , pp. 1197-1198
    • Clark, W.H.1
  • 12
    • 74949143594 scopus 로고    scopus 로고
    • Final version of 2009 AJCC melanoma staging and classification
    • Balch CM, Gershenwald JE, Soong SJ et al. Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol 2009;27:6199-6206.
    • (2009) J Clin Oncol , vol.27 , pp. 6199-6206
    • Balch, C.M.1    Gershenwald, J.E.2    Soong, S.J.3
  • 13
    • 0021686731 scopus 로고
    • Dysplasia, carcinoma in situ, and early invasive cervical carcinoma
    • Nelson JH Jr., Averette HE, Richart RM. Dysplasia, carcinoma in situ, and early invasive cervical carcinoma. CA Cancer J Clin 1984;34:306-327.
    • (1984) CA Cancer J Clin , vol.34 , pp. 306-327
    • Nelson, J.H.1    Averette, H.E.2    Richart, R.M.3
  • 15
    • 36049025193 scopus 로고    scopus 로고
    • Kinetic model of progression of cutaneous melanoma population
    • Gutkowicz-Krusin D, Rabinovitz HS. Kinetic model of progression of cutaneous melanoma population. Melanoma Res 2007;17:354-359.
    • (2007) Melanoma Res , vol.17 , pp. 354-359
    • Gutkowicz-Krusin, D.1    Rabinovitz, H.S.2
  • 16
    • 33644701437 scopus 로고    scopus 로고
    • Normal human melanocyte homeostasis as a paradigm for understanding melanoma
    • Haass NK, Herlyn M. Normal human melanocyte homeostasis as a paradigm for understanding melanoma. J Investig Dermatol Symp Proc 2005; 10:153-163.
    • (2005) J Investig Dermatol Symp Proc , vol.10 , pp. 153-163
    • Haass, N.K.1    Herlyn, M.2
  • 18
    • 0033937121 scopus 로고    scopus 로고
    • Progression to invasive melanoma from malignant melanoma in situ, lentigo maligna type
    • Tannous ZS, Lerner LH, Duncan LM et al. Progression to invasive melanoma from malignant melanoma in situ, lentigo maligna type. Hum Pathol 2000;31:705-708.
    • (2000) Hum Pathol , vol.31 , pp. 705-708
    • Tannous, Z.S.1    Lerner, L.H.2    Duncan, L.M.3
  • 19
    • 0025520665 scopus 로고
    • Ideas in pathology. Malignant melanoma in situ: The evolution of a concept
    • Dubow BE, Ackerman AB. Ideas in pathology. Malignant melanoma in situ: the evolution of a concept. Mod Pathol 1990;3:734-744.
    • (1990) Mod Pathol , vol.3 , pp. 734-744
    • Dubow, B.E.1    Ackerman, A.B.2
  • 20
    • 21844471277 scopus 로고    scopus 로고
    • Variation in the diagnosis, treatment, and management of melanoma in situ: A survey of US dermatologists
    • Charles CA, Yee VS, Dusza SW et al. Variation in the diagnosis, treatment, and management of melanoma in situ: a survey of US dermatologists. Arch Dermatol 2005;141:723-729.
    • (2005) Arch Dermatol , vol.141 , pp. 723-729
    • Charles, C.A.1    Yee, V.S.2    Dusza, S.W.3
  • 21
    • 0036606097 scopus 로고    scopus 로고
    • Reliability of diagnosis of melanoma in situ
    • Megahed M, Schon M, Selimovic D et al. Reliability of diagnosis of melanoma in situ. Lancet 2002;359:1921-1922.
    • (2002) Lancet , vol.359 , pp. 1921-1922
    • Megahed, M.1    Schon, M.2    Selimovic, D.3
  • 22
    • 0035281592 scopus 로고    scopus 로고
    • Dermoscopic criteria for melanoma in situ are similar to those for early invasive melanoma
    • Pizzichetta MA, Argenziano G, Talamini R et al. Dermoscopic criteria for melanoma in situ are similar to those for early invasive melanoma. Cancer 2001;91:992-997.
    • (2001) Cancer , vol.91 , pp. 992-997
    • Pizzichetta, M.A.1    Argenziano, G.2    Talamini, R.3
  • 23
    • 0033886819 scopus 로고    scopus 로고
    • Benign atypical junctional melanocytic hyperplasia associated with intradermal nevi: A common finding that may be confused with melanoma in situ
    • Okamura JM, Barr RJ, Cantos KA. Benign atypical junctional melanocytic hyperplasia associated with intradermal nevi: a common finding that may be confused with melanoma in situ. Mod Pathol 2000;13:857-860.
    • (2000) Mod Pathol , vol.13 , pp. 857-860
    • Okamura, J.M.1    Barr, R.J.2    Cantos, K.A.3
  • 24
    • 0030047023 scopus 로고    scopus 로고
    • Clinical diagnosis and therapy of cutaneous melanoma in situ
    • Bartoli C, Bono A, Clemente C et al. Clinical diagnosis and therapy of cutaneous melanoma in situ. Cancer 1996;77:888-892.
    • (1996) Cancer , vol.77 , pp. 888-892
    • Bartoli, C.1    Bono, A.2    Clemente, C.3
  • 25
    • 67349143381 scopus 로고    scopus 로고
    • Surgical management of mel-anoma-in-situ using a staged marginal and central excision technique
    • Moller MG, Pappas-Politis E, Zager JS et al. Surgical management of mel-anoma-in-situ using a staged marginal and central excision technique. Ann Surg Oncol 2009;16:1526-1536.
    • (2009) Ann Surg Oncol , vol.16 , pp. 1526-1536
    • Moller, M.G.1    Pappas-Politis, E.2    Zager, J.S.3
  • 26
    • 49649092453 scopus 로고    scopus 로고
    • Surgical management of melanoma in situ on chronically sun-damaged skin
    • Clark GS, Pappas-Politis EC, Cherpelis BS et al. Surgical management of melanoma in situ on chronically sun-damaged skin. Cancer Control 2008; 15:216-224.
    • (2008) Cancer Control , vol.15 , pp. 216-224
    • Clark, G.S.1    Pappas-Politis, E.C.2    Cherpelis, B.S.3
  • 27
    • 17444378895 scopus 로고    scopus 로고
    • Treatment of lentigo maligna (melanoma in situ) with the immune response modifier imiquimod
    • Wolf IH, Cerroni L, Kodama K et al. Treatment of lentigo maligna (melanoma in situ) with the immune response modifier imiquimod. Arch Derma-tol 2005;141:510-514.
    • (2005) Arch Derma-tol , vol.141 , pp. 510-514
    • Wolf, I.H.1    Cerroni, L.2    Kodama, K.3
  • 28
    • 0037564587 scopus 로고    scopus 로고
    • Local recurrence in melanoma in situ: Influence of sex, age, site of involvement and therapeutic modalities
    • Zalaudek I, Horn M, Richtig E et al. Local recurrence in melanoma in situ: influence of sex, age, site of involvement and therapeutic modalities. Br J Dermatol 2003;148:703-708.
    • (2003) Br J Dermatol , vol.148 , pp. 703-708
    • Zalaudek, I.1    Horn, M.2    Richtig, E.3
  • 29
    • 0031874753 scopus 로고    scopus 로고
    • Rapid increase in diagnosis of cutaneous melanoma in situ in Sweden, 1968-1992
    • Thorn M, Ponten F, Johansson AM et al. Rapid increase in diagnosis of cutaneous melanoma in situ in Sweden, 1968-1992. Cancer Detect Prev 1998;22:430-437.
    • (1998) Cancer Detect Prev , vol.22 , pp. 430-437
    • Thorn, M.1    Ponten, F.2    Johansson, A.M.3
  • 30
    • 0032912725 scopus 로고    scopus 로고
    • Lentigo maligna and malignant melanoma in situ, lentigo maligna type
    • Flotte TJ, Mihm MC Jr. Lentigo maligna and malignant melanoma in situ, lentigo maligna type. Hum Pathol 1999;30:533-536.
    • (1999) Hum Pathol , vol.30 , pp. 533-536
    • Flotte, T.J.1    Mihm, M.C.2
  • 31
    • 0344418684 scopus 로고    scopus 로고
    • Cancer risk in patients with earlier diagnosis of cutaneous melanoma in situ
    • Wassberg C, Thorn M, Yuen J et al. Cancer risk in patients with earlier diagnosis of cutaneous melanoma in situ. Int J Cancer 1999;83:314-317.
    • (1999) Int J Cancer , vol.83 , pp. 314-317
    • Wassberg, C.1    Thorn, M.2    Yuen, J.3
  • 32
    • 0026492850 scopus 로고
    • Risk classification of life and health insurance applicants with atypical melanocytic hyperplasia or malignant melanoma in situ
    • Wagner RF Jr., Murphy CM. Risk classification of life and health insurance applicants with atypical melanocytic hyperplasia or malignant melanoma in situ. Cutis 1992;50:352-354.
    • (1992) Cutis , vol.50 , pp. 352-354
    • Wagner, R.F.1    Murphy, C.M.2
  • 33
    • 43749096577 scopus 로고    scopus 로고
    • The incidence of second primary invasive melanoma in Queensland, 1982-2003
    • McCaul KA, Fritschi L, Baade P et al. The incidence of second primary invasive melanoma in Queensland, 1982-2003. Cancer Causes Control 2008;19:451-458.
    • (2008) Cancer Causes Control , vol.19 , pp. 451-458
    • McCaul, K.A.1    Fritschi, L.2    Baade, P.3
  • 35
    • 67449150231 scopus 로고    scopus 로고
    • Increasing burden of melanoma in the United States
    • Linos E, Swetter SM, Cockburn MG et al. Increasing burden of melanoma in the United States. J Invest Dermatol 2009;129:1666-1674.
    • (2009) J Invest Dermatol , vol.129 , pp. 1666-1674
    • Linos, E.1    Swetter, S.M.2    Cockburn, M.G.3
  • 36
    • 0141992252 scopus 로고    scopus 로고
    • The melanoma epidemic: Res ipsa loquitur
    • Beddingfield FC 3rd. The melanoma epidemic: res ipsa loquitur. The Oncologist 2003;8:459-465.
    • (2003) The Oncologist , vol.8 , pp. 459-465
    • Beddingfield, F.C.1
  • 37
    • 68849095244 scopus 로고    scopus 로고
    • Staged margin control techniques for surgical excision of lentigo maligna
    • Raziano RM, Clark GS, Cherpelis BS et al. Staged margin control techniques for surgical excision of lentigo maligna. G Ital Dermatol Venereol 2009;144:259-270.
    • (2009) G Ital Dermatol Venereol , vol.144 , pp. 259-270
    • Raziano, R.M.1    Clark, G.S.2    Cherpelis, B.S.3
  • 38
    • 68749083830 scopus 로고    scopus 로고
    • Modified Mohs micrographic surgery for periocular melanoma and melanoma in situ: Long-term experience at Scripps Clinic
    • Shumaker PR, Kelley B, Swann MH et al. Modified Mohs micrographic surgery for periocular melanoma and melanoma in situ: long-term experience at Scripps Clinic. Dermatol Surg 2009;35:1263-1270.
    • (2009) Dermatol Surg , vol.35 , pp. 1263-1270
    • Shumaker, P.R.1    Kelley, B.2    Swann, M.H.3
  • 39
    • 34147105998 scopus 로고    scopus 로고
    • Mohs surgery for the treatment of melanoma in situ: A review
    • Dawn ME, Dawn AG, Miller SJ. Mohs surgery for the treatment of melanoma in situ: a review. Dermatol Surg 2007;33:395-402.
    • (2007) Dermatol Surg , vol.33 , pp. 395-402
    • Dawn, M.E.1    Dawn, A.G.2    Miller, S.J.3
  • 40
    • 64849088533 scopus 로고    scopus 로고
    • Imiquimod and lentigo ma-ligna: A search for prognostic features in a clinicopathological study with long-term follow-up
    • Powell AM, Robson AM, Russell-Jones R et al. Imiquimod and lentigo ma-ligna: a search for prognostic features in a clinicopathological study with long-term follow-up. Br J Dermatol 2009;160:994-998.
    • (2009) Br J Dermatol , vol.160 , pp. 994-998
    • Powell, A.M.1    Robson, A.M.2    Russell-Jones, R.3
  • 41
    • 38449089605 scopus 로고    scopus 로고
    • Treatment of lentigo maligna with imi-quimod 5% cream
    • Hopson B, Richey D, Sajben FP. Treatment of lentigo maligna with imi-quimod 5% cream. J Drugs Dermatol 2007;6:1037-1040.
    • (2007) J Drugs Dermatol , vol.6 , pp. 1037-1040
    • Hopson, B.1    Richey, D.2    Sajben, F.P.3
  • 42
    • 33748900927 scopus 로고    scopus 로고
    • The role of topical immune response modifiers in skin cancer
    • Woodmansee C, Pillow J, Skinner RB Jr. The role of topical immune response modifiers in skin cancer. Drugs 2006;66:1657-1664.
    • (2006) Drugs , vol.66 , pp. 1657-1664
    • Woodmansee, C.1    Pillow, J.2    Skinner, R.B.3
  • 43
    • 0013401756 scopus 로고    scopus 로고
    • SEER, Bethesda, MD: National Cancer Institute
    • SEER. Surveillance Epidemiology and End Results. Bethesda, MD: National Cancer Institute, 2009. Available at http://seer.cancer.gov/.
    • (2009) Surveillance Epidemiology and End Results
  • 45
    • 79959605541 scopus 로고    scopus 로고
    • Surveillance Research Program
    • SEER, Bethesda, MD: National Cancer Institute
    • SEER. Surveillance Research Program, SEER*Stat software. Bethesda, MD: National Cancer Institute, 2009. Available at http://seer.cancer.gov/seerstat/.
    • (2009) SEER*Stat Software
  • 46
    • 69149096758 scopus 로고    scopus 로고
    • Melanoma epidemic: A midsummer night's dream?
    • Levell NJ, Beattie CC, Shuster S et al. Melanoma epidemic: a midsummer night's dream? Br J Dermatol 2009;161:630-634.
    • (2009) Br J Dermatol , vol.161 , pp. 630-634
    • Levell, N.J.1    Beattie, C.C.2    Shuster, S.3
  • 47
    • 33745533912 scopus 로고    scopus 로고
    • Recent trends in cutaneous malignant melanoma in the Yorkshire region of England; incidence, mortality and survival in relation to stage of disease, 1993-2003
    • Downing A, Newton-Bishop JA, Forman D. Recent trends in cutaneous malignant melanoma in the Yorkshire region of England; incidence, mortality and survival in relation to stage of disease, 1993-2003. Br J Cancer 2006;95:91-95.
    • (2006) Br J Cancer , vol.95 , pp. 91-95
    • Downing, A.1    Newton-Bishop, J.A.2    Forman, D.3
  • 48
    • 64049086840 scopus 로고    scopus 로고
    • Incidence of cutaneous malignant melanoma in the Ottawa region: 1996 to 2006
    • Nevins T, Su Y, Doucette S et al. Incidence of cutaneous malignant melanoma in the Ottawa region: 1996 to 2006. J Cutan Med Surg 2008;12:276-281.
    • (2008) J Cutan Med Surg , vol.12 , pp. 276-281
    • Nevins, T.1    Su, Y.2    Doucette, S.3
  • 49
    • 0033011941 scopus 로고    scopus 로고
    • Melanoma in Kauai, Hawaii, 1981-1990: The significance of in situ melanoma and the incidence trend
    • Chuang TY, Charles J, Reizner GT et al. Melanoma in Kauai, Hawaii, 1981-1990: the significance of in situ melanoma and the incidence trend. Int J Dermatol 1999;38:101-107.
    • (1999) Int J Dermatol , vol.38 , pp. 101-107
    • Chuang, T.Y.1    Charles, J.2    Reizner, G.T.3
  • 51
    • 33846785369 scopus 로고    scopus 로고
    • Early melanoma diagnosis: A success story that leaves room for improvement
    • Halpern AC, Lieb JA. Early melanoma diagnosis: a success story that leaves room for improvement. Curr Opin Oncol 2007;19:109-115.
    • (2007) Curr Opin Oncol , vol.19 , pp. 109-115
    • Halpern, A.C.1    Lieb, J.A.2
  • 52
    • 73049117444 scopus 로고    scopus 로고
    • The skin awareness study: Promoting thorough skin self-examination for skin cancer among men 50 years or older
    • Janda M, Baade PD, Youl PH et al. The skin awareness study: promoting thorough skin self-examination for skin cancer among men 50 years or older. Contemp Clin Trials 2010;31:119-130.
    • (2010) Contemp Clin Trials , vol.31 , pp. 119-130
    • Janda, M.1    Baade, P.D.2    Youl, P.H.3
  • 53
    • 28944433501 scopus 로고    scopus 로고
    • Molecular mechanisms in cancer: What should clinicians know?
    • Ajani J, Allgood V. Molecular mechanisms in cancer: what should clinicians know? Semin Oncol 2005;32:2-4.
    • (2005) Semin Oncol , vol.32 , pp. 2-4
    • Ajani, J.1    Allgood, V.2
  • 55
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat Med 2004;10:789-799.
    • (2004) Nat Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 56
    • 47049123542 scopus 로고    scopus 로고
    • Trends in prognostic factors and survival from cutaneous melanoma in Yorkshire, UK and New South Wales, Australia between 1993 and 2003
    • Downing A, Yu XQ, Newton-Bishop J et al. Trends in prognostic factors and survival from cutaneous melanoma in Yorkshire, UK and New South Wales, Australia between 1993 and 2003. Int J Cancer 2008;123:861-866.
    • (2008) Int J Cancer , vol.123 , pp. 861-866
    • Downing, A.1    Yu, X.Q.2    Newton-Bishop, J.3
  • 57
    • 76649102084 scopus 로고    scopus 로고
    • Melanoma thickness trends in the United States, 1988-2006
    • Criscione VD, Weinstock MA. Melanoma thickness trends in the United States, 1988-2006. J Invest Dermatol 2010;130:793-797.
    • (2010) J Invest Dermatol , vol.130 , pp. 793-797
    • Criscione, V.D.1    Weinstock, M.A.2
  • 58
    • 30544445872 scopus 로고    scopus 로고
    • Trends for in situ and invasive melanoma in Queensland, Australia, 1982-2002
    • Coory M, Baade P, Aitken J et al. Trends for in situ and invasive melanoma in Queensland, Australia, 1982-2002. Cancer Causes Control 2006;17:21-27.
    • (2006) Cancer Causes Control , vol.17 , pp. 21-27
    • Coory, M.1    Baade, P.2    Aitken, J.3
  • 59
    • 59949092923 scopus 로고    scopus 로고
    • Screening for skin cancer: An update of the evidence for the U.S. Preventive Services Task Force
    • Wolff T, Tai E, Miller T. Screening for skin cancer: an update of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med 2009; 150:194-198.
    • (2009) Ann Intern Med , vol.150 , pp. 194-198
    • Wolff, T.1    Tai, E.2    Miller, T.3
  • 61
    • 33646227198 scopus 로고    scopus 로고
    • Progress and prospects on melanoma: The way forward for early detection and reduced mortality
    • Weinstock MA. Progress and prospects on melanoma: the way forward for early detection and reduced mortality. Clin Cancer Res 2006;12:2297s-2300s.
    • (2006) Clin Cancer Res , vol.12
    • Weinstock, M.A.1
  • 62
    • 34548550721 scopus 로고    scopus 로고
    • A retrospective study addressed to understanding what predicts severe histological dysplasia/early melanoma in excised atypical melanocytic lesions
    • Strauss RM, Elliott F, Affleck P et al. A retrospective study addressed to understanding what predicts severe histological dysplasia/early melanoma in excised atypical melanocytic lesions. Br J Dermatol 2007;157:758-764.
    • (2007) Br J Dermatol , vol.157 , pp. 758-764
    • Strauss, R.M.1    Elliott, F.2    Affleck, P.3
  • 63
    • 0030746278 scopus 로고    scopus 로고
    • Melanoma and melanoma in situ: Build a better diagnosis through architecture
    • McCalmont TH. Melanoma and melanoma in situ: build a better diagnosis through architecture. Semin Cutan Med Surg 1997;16:97-107.
    • (1997) Semin Cutan Med Surg , vol.16 , pp. 97-107
    • McCalmont, T.H.1


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