Generation and characterization of neurogenin1-GFP transgenic medaka with potential for rapid developmental neurotoxicity screening

Aquatic Toxicology

Volumn 105, Issue 1-2, 2011, Pages 127-135

  Fan, Chun Yang ^a,b,d   Simmons, Steven O ^a   Law, Sheran H W ^c,e   Jensen, Karl ^a   Cowden, John ^a,f   Hinton, David ^c   Padilla, Stephanie ^a   Ramabhadran, Ram ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c DUKE UNIVERSITY   (United States)

^d SYNGENTA BIOTECHNOLOGY INC   (United States)

^e EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^f U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Developmental neurotoxicity screening; GFP; Transgenic medaka; Zebrafish neurogenin 1

Indexed keywords

GREEN FLUORESCENT PROTEIN; NEUROGENIN 1;

FISH; GENE EXPRESSION; GENETIC ANALYSIS; OBSERVATIONAL METHOD; PROTEIN; TOXICITY TEST;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; EMBRYO; GENE EXPRESSION; NEUROTOXICITY; NGN1 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORYZIAS; PRIORITY JOURNAL; PROMOTER REGION; SCREENING; TRANSGENE; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BIOLOGICAL MARKERS; FISH PROTEINS; GREEN FLUORESCENT PROTEINS; NERVE TISSUE PROTEINS; NERVOUS SYSTEM; ORYZIAS; RNA, MESSENGER; TOXICITY TESTS; ZEBRAFISH PROTEINS;

DANIO RERIO; ORYZIINAE; RODENTIA;

EID: 79959614379     PISSN: 0166445X     EISSN: 18791514     Source Type: Journal    
DOI: 10.1016/j.aquatox.2011.05.017     Document Type: Article

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