Platinum nanoparticles and their cellular uptake and DNA platination at non-cytotoxic concentrations

Archives of Toxicology

Volumn 85, Issue 7, 2011, Pages 799-812

  Gehrke, Helge ^a   Pelka, Joanna ^a   Hartinger, Christian G ^a   Blank, Holger ^b   Bleimund, Felix ^b   Schneider, Reinhard ^b   Gerthsen, Dagmar ^b   Bräse, Stefan ^b   Crone, Marlene ^b   Türk, Michael ^b   Marko, Doris ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

Author keywords

Cellular localisation; Cytotoxicity; DNA complexes; NP translocation

Indexed keywords

BETA CYCLODEXTRIN; DNA; NANOPARTICLE; PLATINUM NANOPARTICLE; UNCLASSIFIED DRUG;

ARTICLE; CELL AGGREGATION; CELL ASSAY; CELL NUCLEUS; CELL STRAIN CACO 2; CELL STRAIN HT29; CELL TRANSPORT; CHEMICAL REACTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DNA MODIFICATION; DNA STRAND BREAKAGE; DRUG CYTOTOXICITY; DRUG DNA INTERACTION; DRUG UPTAKE; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MITOCHONDRION; PARTICLE SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SUPERCRITICAL FLUID REACTIVE DEPOSITION; TRANSMISSION ELECTRON MICROSCOPY;

CACO-2 CELLS; CELL POLARITY; CELL PROLIFERATION; CELL SURVIVAL; CULTURE MEDIA, CONDITIONED; CYTOPLASMIC VESICLES; DNA; ENTEROCYTES; HT29 CELLS; HUMANS; INTESTINAL ABSORPTION; MATERIALS TESTING; METAL NANOPARTICLES; MUTAGENS; ORGANOPLATINUM COMPOUNDS; OSMOLAR CONCENTRATION; PARTICLE SIZE; PLATINUM; SOLUBILITY; TIME FACTORS;

EID: 79959611911     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-010-0636-3     Document Type: Article

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