Sensitivity and gene expression profile of fresh human acute myeloid leukemia cells exposed ex vivo to AS602868

Cancer Chemotherapy and Pharmacology

Volumn 68, Issue 1, 2011, Pages 97-105

  Jordheim, Lars Petter ^a,b   Plesa, Adriana ^c   Dreano, Michel ^d   Cros Perrial, Emeline ^a   Keime, Céline ^a,b   Herveau, Stéphanie ^a   Demangel, Delphine ^b   Vendrell, Julie A ^b   Dumontet, Charles ^a,b,c  

^a UNIVERSITÉ LYON 1   (France)

^b LCMT   (France)

^c HOSPICES CIVILS DE LYON   (France)

^d MERCK SERONO S A   (Switzerland)

Author keywords

Acute myeloid leukemia; AS602868; Gene expression; Microarray; Sensitivity

Indexed keywords

1 [5 HYDROXY 2 (2 THIENYL) 4 QUINAZOLINYLAMINO] 3 METHYL 2,5 PYRROLEDIONE; CYTARABINE; DAUNORUBICIN; ETOPOSIDE; I KAPPA B ALPHA; I KAPPA B KINASE; I KAPPA B KINASE 2; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EXPOSURE; DRUG MECHANISM; DRUG POTENTIATION; DRUG SENSITIVITY; ENZYME INHIBITION; EX VIVO STUDY; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CELL LINE, TUMOR; CYTARABINE; DAUNORUBICIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ETOPOSIDE; GENE EXPRESSION PROFILING; HUMANS; I-KAPPA B PROTEINS; LEUKEMIA, MYELOID, ACUTE; LYMPHOCYTES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PYRIMIDINES;

EID: 79959607849     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-010-1458-y     Document Type: Article

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