Pseudocontinuous arterial spin labeling reveals dissociable effects of morphine and alcohol on regional cerebral blood flow

Journal of Cerebral Blood Flow and Metabolism

Volumn 31, Issue 5, 2011, Pages 1321-1333

  Khalili Mahani, Najmeh ^a,b   Van Osch, Matthias J P ^b   Baerends, Evelinda ^a,b   Soeter, Roelof P ^a,b   De Kam, Marieke ^c   Zoethout, Remco W M ^b,c   Dahan, Albert ^b   Van Buchem, Mark A ^a,b   Van Gerven, Joop M A ^b,c   Rombouts, Serge A R B ^a,b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c CENTRE FOR HUMAN DRUG RESEARCH   (Netherlands)

Author keywords

alcohol; cerebral blood flow; functional brain imaging; morphine; perfusion weighted MRI; pharma fMRI

Indexed keywords

ALCOHOL; MORPHINE; PLACEBO; CENTRAL DEPRESSANT AGENT; NARCOTIC AGENT;

ADULT; ANTERIOR CINGULATE; ARTICLE; BRAIN BLOOD FLOW; BRAIN MAPPING; BRAIN STEM; CEREBELLUM; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG RESEARCH; HIPPOCAMPUS; HUMAN; HUMAN EXPERIMENT; INSULA; MALE; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PSEUDOCONTINUOUS ARTERIAL SPIN LABELING; PUTAMEN; RANDOMIZED CONTROLLED TRIAL; SENSORIMOTOR CORTEX; SPIN LABELING; VALIDATION PROCESS; ADOLESCENT; BRAIN CIRCULATION; CLINICAL TRIAL; COMPUTER ASSISTED DIAGNOSIS; CONTROLLED CLINICAL TRIAL; DOUBLE BLIND PROCEDURE; DRUG EFFECT; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; SENSITIVITY AND SPECIFICITY;

ADOLESCENT; ADULT; BRAIN MAPPING; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CEREBROVASCULAR CIRCULATION; DOUBLE-BLIND METHOD; ETHANOL; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MORPHINE; NARCOTICS; SENSITIVITY AND SPECIFICITY; SPIN LABELS; YOUNG ADULT;

EID: 79959588915     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2010.234     Document Type: Article

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