Identification of crucial yeast inhibitors in bio-ethanol and improvement of fermentation at high pH and high total solids

Bioresource Technology

Volumn 102, Issue 16, 2011, Pages 7486-7493

  Huang, Hongzhi ^a   Guo, Xinyan ^a   Li, Dongmin ^a   Liu, Mengmeng ^a   Wu, Jiafang ^a   Ren, Haiyu ^a  

^a Novozymes (China) Investment Co Ltd   (China)

Author keywords

Fermentation; High pH; High total solids; Inhibitors

Indexed keywords

BACTERIAL CONTAMINATION; CORN STOVER; CRITICAL LEVEL; ETHANOL YIELD; HIGH PH; INHIBITORY EFFECT; TOTAL SOLIDS; WEAK ACIDS;

ACETIC ACID; ALDEHYDES; ALUMINUM CORROSION; BACTERIOLOGY; BIOETHANOL; ENZYMATIC HYDROLYSIS; ETHANOL; FERMENTATION; FORMIC ACID; PHENOLS; YEAST;

PH EFFECTS;

ACETIC ACID; ALCOHOL; ALDEHYDE; BIOETHANOL; FORMIC ACID; PHENOL; UNCLASSIFIED DRUG;

ACETIC ACID; ALDEHYDE; BACTERIUM; BIOFUEL; BIOTECHNOLOGY; ESTER; ETHANOL; FERMENTATION; FORMIC ACID; IDENTIFICATION METHOD; INHIBITOR; MAIZE; PH; PHENOL; YEAST;

ARTICLE; BACTERIUM CONTAMINATION; CORN; FERMENTATION; HYDROLYSIS; PH; PRIORITY JOURNAL; SOLID; YEAST;

ACETIC ACID; BACTERIA; BIOFUELS; BIOMASS; ETHANOL; FERMENTATION; FORMIC ACIDS; FURALDEHYDE; HYDROGEN-ION CONCENTRATION; LIGNIN; PHENOLS; SACCHAROMYCES CEREVISIAE; ZEA MAYS;

BACTERIA (MICROORGANISMS); ZEA MAYS;

EID: 79959587185     PISSN: 09608524     EISSN: 18732976     Source Type: Journal    
DOI: 10.1016/j.biortech.2011.05.008     Document Type: Article

References (20)

1. Almeida J.R., Modig T., Petersson A., Hahn-Hagerdal B., Liden G., Gorwa-Grauslund M. Increased tolerance and conversion of inhibitors in lignocellulosic hydrolysates by Saccharomyces cerevisiae. J. Chem. Technol. Biotechnol. 2007, 82:340-349.
2. Alvira P., Tomas-Pejo E., Ballesteros M., Negro M.J. Pretreatment technologies for an efficient bioethanol production process based on enzymatic hydrolysis: a review. Bioresour. Technol. 2010, 101:4851-4861.
3. Casey E., Sedlak M., Ho N.W.Y., Mosier N.S. Effect of acetic acid and pH on the cofermentation of glucose and xylose to ethanol by a genetically engineered strain of Saccharomyces cerevisiae. FEMS Yeast Res. 2010, 10:385-393.
4. Delgenes J.P., Moletta R., Navarro J.M. Effects of lignocelluloses degradation products on ethanol fermentations of glucose and xylose by Saccharomyces cerevisiae, Zymomonas mobilis, Pichia stipitis, and Candida shehatae. Enzyme Microb. Technol. 1996, 19:220-225.
5. Green H., Shelef G. Ethanol fermentation of acid hydrolysate of municipal solid waste. The Chem. Eng. J. 1989, 40:B25-B28.
6. Himmel M.E., Ding S.Y., Johnson D.K., Adney W.S., Nimlos M.R., Brady J.W., Foust T.D. Biomass recalcitrance: engineering plants and enzymes for biofuels production. Science 2007, 315:804-807.
7. Huang C.F., Lin T.H., Guo G.L., Hwang W.S. Enhanced ethanol production by fermentation of rice straw hydrolysate without detoxification using a newly adapted strain of Pichia stipitis. Bioresour. Technol. 2009, 100:3914-3929.
8. Jonsson L.J., Palmqvist E., Nilvebrant N.O., Hahn-Hagerdal B. Detoxification of wood hydrolysates with laccase and peroxidase from the white-rot fungus Trametes versicolor. Appl. Microbiol. Biotechnol. 1998, 49:691-697.
9. Jurado M., Prieto A., Martinez-Alcala A., Martinez A.T., Martinez M.J. Laccase detoxification of steam-exploded wheat straw for second generation bioethanol. Bioresour. Technol. 2009, 100:6378-6384.
10. Kadar Z., Maltha S.F., Szengyel Z., Reczey K., Laat W.D. Ethanol fermentation of various pretreated and hydrolyzed substrate at low initial pH. Appl. Biochem. Biotechnol. 2007, 136-140:847-858.
11. Klinke H.B., Thomsen A.B., Ahring B.K. Inhibition of ethanol-producing yeast and bacteria by degradation products produced during pre-treatment of biomass. Appl. Biochem. Biotechnol. 2004, 66:10-26.
12. Larsson S., Palmqvist E., Hahn-Hagerdal B., Tengborg C., Stenberg K., Zacchi G., Nilvebrant N. The generation of fermentation inhibitors during dilute acid hydrolysis of softwood. Enzyme Microb. Technol. 1999, 24:151-159.
13. Maiorella B., Blanch H.W., Wilke C.R. By-product inhibition effects on ethanolic fermentation by Saccharomyces cerevisiae. Biotechnol. Bioeng. 1983, XXV:103-121.
14. Nilvebrant N.O., Reimann A., Larsson S., Jonsson L.J. Detoxification of lignocelluloses hydrolysates with ion-exchange resins. Appl. Biochem. Biotechnol. 2001, 91-93:35-49.
15. Palmqvist E., Almeida J.S., Hahn-Hagerdal B. Influence of furfural on anaerobic glycolytic kinetics of Saccharomyces cerevisiae in batch culture. Biotechnol. Bioeng. 1999, 62:447-454.
16. Palmqvist E., Hahn-Hagerdal B. Fermentation of lignocellulosic hydrolysates. I: inhibition and detoxification. Bioresour. Technol. 2000, 74:17-24.
17. Palmqvist E., Hahn-Hagerdal B. Fermentation of lignocellulosic hydrolysates. II: inhibitors and mechanisms of inhibition. Bioresour. Technol. 2000, 74:25-33.
18. Perry N.B., Burgess E.J., Glennie V.L. Echinacea standardization: analytical methods for phenolic compounds and typical levels in medicinal species. J. Agric. Food Chem. 2001, 49:1702-1706.
19. Petersson A., Almeida J.R., Modig T., Karhumaa K., Hahn-Hagerdal B., Gorwa-Grauslund M.F., Liden G. A 5-hydroxymethyl furfural reducing enzyme encoded by the Saccharomyces cerevisiae ADH6 gene conveys HMF tolerance. Yeast 2006, 23:455-464.
20. Qian C.R., Huang Y.X. Experimental Handbook of Microbiology 1999, Peking University Press, Beijing, pp. 100-101.