The generation of fermentation inhibitors during dilute acid hydrolysis of softwood

Enzyme and Microbial Technology

Volumn 24, Issue 3-4, 1999, Pages 151-159

  Larsson, Simona ^a   Palmqvist, Eva ^a   Hahn Hägerdal, Bärbel ^a   Tengborg, Charlotte ^a   Stenberg, Kerstin ^a   Zacchi, Guido ^a   Nilvebrant, Nils Olof ^b  

^a LUND UNIVERSITY   (Sweden)

^b INNVENTIA AB   (Sweden)

Author keywords

Dilute acid hydrolysis; Ethanolic fermentation; Fermentation inhibitors; Saccharomyces cerevisiae; Weak acids

Indexed keywords

ACETIC ACID; BIOASSAY; COMPOSITION EFFECTS; ETHANOL; FERMENTATION; GLUCOSE; HYDROLYSIS; SULFURIC ACID; YEAST;

FORMIC ACID; HYDROXYMETHYLFURFURAL; LEVULINIC ACID; MANNOSE; MONOSACCHARIDE;

XYLOSE;

ARTICLE; CULTURE MEDIUM; ENERGY RESOURCE; ENZYME ACTIVITY; FERMENTATION; HYDROLYSIS; PH; SACCHAROMYCES CEREVISIAE; TEMPERATURE; WOOD;

EID: 0345722732     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0141-0229(98)00101-X     Document Type: Article

References (40)

1. von Sivers M., Zacchi G., Olsson L., Hahn-Hägerdal B. Cost analysis of ethanol production from willow using recombinant Escherichia coli. Biotechnol. Prog. 10:1994;555-560.
2. Olsson L., Hahn-Hägerdal B. Fermentation of lignocellulose hydrolysates for ethanol production. Enzyme Microb. Technol. 18:1996;312-331.
3. Brownlie D. Wood as a chemical raw product. Chem. Ind. 59:1940;671-675.
4. Harris E.E., Beglinger E., Hajny G.J., Sherrard E.C. Hydrolysis of wood. Treatment with sulphuric acid in a stationary digester. J. Ind. Eng. Chem. 37:1945;12-23.
5. Beck M.J. Factors affecting efficiency of biomass fermentation to ethanol. Biotechnol. Bioeng. Symp. 17:1986;617-627.
6. Wright J.D., Power A.J. Comparative technical evaluation of acid hydrolysis processes for conversion of cellulose to alcohol. Energy Biomass Wastes. 10:1987;949-971.
7. Baugh K.D., Levy J.A., McCarty P.L. Thermochemical pretreatment of lignocellulose to enhance methane fermentation. II. Evaluation and application of pretreatment model. Biotechnol. Bioeng. 31:1988;62-70.
8. Clausen E.C., Gaddy J.L. Ethanol from biomass by concentrated acid hydrolysis and fermentation. Energy Biomass Wastes. 12:1988;1319-1342.
9. Fan L.T., Lee Y.-H., Gharpuray M.M. The nature of lignocellulosics and their pretreatments for enzymatic hydrolysis. Adv. Biochem. Eng. Biotechnol. 23:1982;158-187.
10. 4 impregnation of softwood prior to steam pretreatment on ethanol production. Appl. Biochem. Biotechnol. 70-72:1998;3-15.
11. Jones J.L., Semrau K.T. Wood hydrolysis for ethanol production-Previous experience and the economics of selected processes. Biomass. 5:1984;109-135.
12. Parekh S., Wayman M. Fermentation of cellobiose and wood sugars to ethanol by Candida shehatae and Pichia stipitis. Biotechnol. Lett. 8:(8):1986;597-600.
13. Quereshi N., Manderson G.J. Bioconversion of renewable resources into ethanol An economic evaluation of selected hydrolysis, fermentation, and membrane technologies . Energy Sources. 17:1994;241-265.
14. Parisi F. Advances in lignocellulosics hydrolysis and in the utilization of the hydrolyzates. Adv. Biochem. Eng. Biotechnol. 38:1989;53-87.
15. Krumbein. Wood saccharification. Rund. Deutsch. Tech. 1938, 12, 1-2.
16. Sanchez B., Bautista J. Effects of furfural and 5-hydroxymethylfurfural on the fermentation of Saccharomyces cerevisiae and biomass production from Candida guillierimondii. Enzyme Microb. Technol. 10:1988;315-318.
17. Saeman J.F. Kinetics of wood saccharification. Hydrolysis of cellulose and decomposition of sugars in dilute acid at high temperature. Ind. Eng. Chem. 37:(1):1945;43-52.
18. Ulbricht R.J., Northup S.J., Thomas J.A. A review of 5-hydroxymethylfurfural (HMF) in parenteral solutions. Fund. Appl. Toxicol. 4:1984;843-853.
19. Clark T.A., Mackie K.L. Fermentation inhibitors in wood hydrolysates derived from the softwood Pinus radiata. Chem. Technol. Biotechnol. 34:(B):1984;101-110.
20. Dunlop A. Furfural formation and behaviour. Ind. Eng. Chem. 40:(2):1948;204-209.
21. Janshekar H., Fiechter A. Lignin Biosynthesis, application, and degradation . Adv. Biochem. Eng. Biotechnol. 27:1983;120-174.
22. Ando S., Arai I., Kiyoto K., Hanai S. Identification of aromatic monomers in steam-exploded poplar and their influences on ethanol fermentation by Saccharomyces cerevisiae. J. Ferment. Technol. 64:(6):1986;567-570.
23. Maiorella B., Blanch H.W., Wilke C.R. By-product inhibition effects on ethanolic fermentation by Saccharomyces cerevisiae. Biotechnol. Bioeng. 25:1983;103-121.
24. Overend R.P., Chornet E. Fractionation of lignocellulosics by steam-aqueous pretreatments. Phil. Trans. R. Soc. Lond. 321:(A):1987;523-536.
25. Chum H.L., Johnson D.K., Black S.K., Overend R.P. Pretreatment-catalyst effects of the combined severity parameter. Appl. Biochem. Biotechnol. 24/25:1990;1-14.
26. th :1990;234 Oxford University Press, Oxford.
27. th Ed. CRC Press, Ohio, 1968-1969, D-90.
28. Soni M.L., Mehrotra R.N., Kapoor R.C. Dissociation constant and some thermodynamic parameters of laevulinic acid. Indian J. Chem. 21A:(2):1982;196-197.
29. Garoff, N. Analysis of wood hydrolysates with capillary electrophoresis. M. Sc. thesis (in Swedish), Department of Wood Chemistry, Royal Institute of Technology, Stockholm, 1997, 59.
30. Tran A.V., Chambers R.P. Ethanol fermentation of red oak acid prehydrolysate by the yeast Pichia stipitis CBS 5776. Enzyme Microb. Technol. 8:1986;439-444.
31. Buchert J., Puls J., Poutanen K. The use of steamed hemicellulose as substrate in microbial conversions. Appl. Microbiol. Biotechnol. 20/21:1989;300-318.
32. Palmqvist E., Hahn-Hägerdal B., Galbe M., Zacchi G. The effect of water-soluble inhibitors from steam-pretreated willow on enzymatic hydrolysis and ethanol fermentation. Enzyme Microb. Technol. 19:1996;470-476.
33. Palmqvist E., Hahn-Hägerdal B., Szengyel Z., Zacchi G., Rèczey K. Simultaneous detoxification and enzyme production of hemicellulose hydrolysates obtained after steam pretreatment. Enzyme Microb. Technol. 20:1997;286-293.
34. Taherzadeh M.J., Eklund R., Gustaffson L., Niklasson C., Lidén G. Characterization and fermentation of dilute-acid hydrolyzates from wood. Ind. Eng. Chem. Res. 36:(11):1997;4659-4665.
35. Villa G.P., Bartroli R., López R., Guerra M., Enrique M., Penas M., Rodríquez E., Redondo D., Iglesias I., Díaz M. Microbial transformation of furfural to furfuryl alcohol by Saccharomyces cerevisiae. Acta Biotechnol. 12:1992;509-512.
36. Palmqvist, E. Fermentation of lignocellulose hydrolysates: Inhibition and fermentation. Ph.D. thesis, Department of Applied Microbiology, Lund University, Lund, Sweden, 1998, 61.
37. Chung I.S., Lee Y.Y. Ethanol fermentation of crude acid hydrolyzate of cellulose using high-level yeast inocula. Biotechnol. Bioeng. 27:1984;308-315.
38. Pampulha M.E., Lourero-Dias M.C. Combined effect of acetic acid, pH, and ethanol on intracellular pH of fermenting yeast. Appl. Microbiol. Biotechnol. 31:1989;547-550.
39. Verdyn C., Postma E., Scheffers A.W., van Dijken J.P. Energetics of Saccharomyces cerevisiae in anaerobic glucose-limited chemostat cultures. J. Gen. Microbiol. 136:1990;405-412.
40. Russel J.B. Another explanation for the toxicity of fermentation acids at low pH Anion accumulation versus uncoupling . J. Appl. Bacteriol. 73:1992;363-370.