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Volumn 16, Issue 6, 2011, Pages 886-895

Outcomes after combined modality therapy for EGFR-mutant and wild-type locally advanced NSCLC

Author keywords

Epidermal growth factor receptor; Local Combined modality therapy; Mutation; Neoplasm recurrence; Non small cell lung carcinoma; Radiation therapy

Indexed keywords

CARBOPLATIN; CISPLATIN; DOCETAXEL; ETOPOSIDE; PACLITAXEL; PLATINUM COMPLEX;

EID: 79959584959     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2011-0040     Document Type: Article
Times cited : (55)

References (36)
  • 1
    • 0346236869 scopus 로고    scopus 로고
    • Long-term benefit is observed ina phase III comparison of sequential vs concurrent chemo-radiation for patients with unresected stage III NSCLC: RTOG 94-10 [Abstract 2499]
    • Curran W, Scott C, Langer C et al. Long-term benefit is observed ina phase III comparison of sequential vs concurrent chemo-radiation for patients with unresected stage III NSCLC: RTOG 94-10 [Abstract 2499]. J Clin Oncol 2003;22:621.
    • (2003) J Clin Oncol , vol.22 , pp. 621
    • Curran, W.1    Scott, C.2    Langer, C.3
  • 2
    • 0038688474 scopus 로고    scopus 로고
    • Consolidation docetaxel after concurrent chemoradiotherapy in stage IIIB non-small-cell lung cancer: Phase II Southwest Oncology Group Study S9504
    • Gandara DR, Chansky K, Albain KS et al. Consolidation docetaxel after concurrent chemoradiotherapy in stage IIIB non-small-cell lung cancer: Phase II Southwest Oncology Group Study S9504. J Clin Oncol 2003;21: 2004-2010.
    • (2003) J Clin Oncol , vol.21 , pp. 2004-2010
    • Gandara, D.R.1    Chansky, K.2    Albain, K.S.3
  • 3
    • 57449090435 scopus 로고    scopus 로고
    • Phase III study of cisplatin, etoposide, and concurrent chest radiation with or without consolidation do-cetaxel in patients with inoperable stage III non-small-cell lung cancer: The Hoosier Oncology Group and U.S. Oncology
    • Hanna N, Neubauer M, Yiannoutsos C, et al. Phase III study of cisplatin, etoposide, and concurrent chest radiation with or without consolidation do-cetaxel in patients with inoperable stage III non-small-cell lung cancer: The Hoosier Oncology Group and U.S. Oncology. J Clin Oncol 2008;26:5755-5760.
    • (2008) J Clin Oncol , vol.26 , pp. 5755-5760
    • Hanna, N.1    Neubauer, M.2    Yiannoutsos, C.3
  • 4
    • 45149102984 scopus 로고    scopus 로고
    • Phase III trial of maintenance ge-fitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non-small-cell lung cancer: SWOG S0023
    • Kelly K, Chansky K, Gaspar LE et al. Phase III trial of maintenance ge-fitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non-small-cell lung cancer: SWOG S0023. J Clin Oncol 2008;26:2450-2456.
    • (2008) J Clin Oncol , vol.26 , pp. 2450-2456
    • Kelly, K.1    Chansky, K.2    Gaspar, L.E.3
  • 5
    • 34248651350 scopus 로고    scopus 로고
    • Induction chemotherapy followed by chemoradiotherapy compared with chemoradiotherapy alone for regionally advanced unresectable stage III non-small-cell lung cancer: Cancer and Leukemia Group B
    • Vokes EE, Herndon JE 2nd, Kelley MJ et al. Induction chemotherapy followed by chemoradiotherapy compared with chemoradiotherapy alone for regionally advanced unresectable stage III non-small-cell lung cancer: Cancer and Leukemia Group B. J Clin Oncol 2007;25:1698-1704.
    • (2007) J Clin Oncol , vol.25 , pp. 1698-1704
    • Vokes, E.E.1    Herndon, J.E.2    Kelley, M.J.3
  • 6
    • 67651241508 scopus 로고    scopus 로고
    • Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: A phase III randomised controlled trial
    • Albain KS, Swann RS, Rusch VW et al. Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: A phase III randomised controlled trial. Lancet 2009;374:379-386.
    • (2009) Lancet , vol.374 , pp. 379-386
    • Albain, K.S.1    Swann, R.S.2    Rusch, V.W.3
  • 7
    • 0037102282 scopus 로고    scopus 로고
    • Concurrent cisplatin, etopo-side, and chest radiotherapy in pathologic stage IIIB non-small-cell lung cancer: A Southwest Oncology Group phase II study, SWOG 9019
    • Albain KS, Crowley JJ, Turrisi AT et al. Concurrent cisplatin, etopo-side, and chest radiotherapy in pathologic stage IIIB non-small-cell lung cancer: A Southwest Oncology Group phase II study, SWOG 9019. J Clin Oncol 2002;20:3454-3460.
    • (2002) J Clin Oncol , vol.20 , pp. 3454-3460
    • Albain, K.S.1    Crowley, J.J.2    Turrisi, A.T.3
  • 8
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-2139.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 9
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Jänne PA, Lee JC et al. EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science 2004;304:1497-1500.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Jänne, P.A.2    Lee, J.C.3
  • 10
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 2004; 101:13306-13311.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 11
    • 77953930730 scopus 로고    scopus 로고
    • Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
    • Maemondo M, Inoue A, Kobayashi K et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 2010;362: 2380-2388.
    • (2010) N Engl J Med , vol.362 , pp. 2380-2388
    • Maemondo, M.1    Inoue, A.2    Kobayashi, K.3
  • 12
    • 75249087060 scopus 로고    scopus 로고
    • Gefitinib versus cisplatin plus do-cetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): An open label, randomised phase 3 trial
    • Mitsudomi T, Morita S, Yatabe Y et al. Gefitinib versus cisplatin plus do-cetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): An open label, randomised phase 3 trial. Lancet Oncol 2010;11:121-128.
    • (2010) Lancet Oncol , vol.11 , pp. 121-128
    • Mitsudomi, T.1    Morita, S.2    Yatabe, Y.3
  • 13
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok TS, Wu YL, Thongprasert S et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009;361:947-957.
    • (2009) N Engl J Med , vol.361 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3
  • 14
    • 74949133978 scopus 로고    scopus 로고
    • American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer
    • Azzoli CG, Baker S Jr, Temin S et al. American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer. J Clin Oncol 2009;27:6251-6266.
    • (2009) J Clin Oncol , vol.27 , pp. 6251-6266
    • Azzoli, C.G.1    Baker, S.2    Temin, S.3
  • 15
    • 24944553737 scopus 로고    scopus 로고
    • Randomized phase III trial of sequential chemoradiotherapy compared with concurrent chemoradiotherapy in locally advanced non-small-cell lung cancer: Groupe Lyon-Saint-Eti-enne d'Oncologie Thoracique-Groupe Frana ̧is de Pneumo-Cancérologie NPC 95-01 Study
    • Fournel P, Robinet G, Thomas P et al. Randomized phase III trial of sequential chemoradiotherapy compared with concurrent chemoradiotherapy in locally advanced non-small-cell lung cancer: Groupe Lyon-Saint-Eti-enne d'Oncologie Thoracique-Groupe Frana ̧is de Pneumo-Cancérologie NPC 95-01 Study. J Clin Oncol 2005;23:5910-5917.
    • (2005) J Clin Oncol , vol.23 , pp. 5910-5917
    • Fournel, P.1    Robinet, G.2    Thomas, P.3
  • 16
    • 0032858243 scopus 로고    scopus 로고
    • Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vin-desine, and cisplatin in unresectable stage III non-small-cell lung cancer
    • Furuse K, Fukuoka M, Kawahara M, et al. Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vin-desine, and cisplatin in unresectable stage III non-small-cell lung cancer. J Clin Oncol 1999;17:2692-2699.
    • (1999) J Clin Oncol , vol.17 , pp. 2692-2699
    • Furuse, K.1    Fukuoka, M.2    Kawahara, M.3
  • 17
    • 0041563993 scopus 로고    scopus 로고
    • The epidermal growth factor receptor mediates radioresistance
    • Liang K, Ang KK, Milas L, et al. The epidermal growth factor receptor mediates radioresistance. Int J Radiat Oncol Biol Phys 2003;57:246-254.
    • (2003) Int J Radiat Oncol Biol Phys , vol.57 , pp. 246-254
    • Liang, K.1    Ang, K.K.2    Milas, L.3
  • 18
    • 17044372038 scopus 로고    scopus 로고
    • Radiosensitivityof tumor cell lines after pretreatment with the EGFR tyrosine kinase inhibitor ZD1839 (Iressa)
    • Burdak-Rothkamm S, Rübe CE, Nguyen TP, et al. Radiosensitivityof tumor cell lines after pretreatment with the EGFR tyrosine kinase inhibitor ZD1839 (Iressa). Strahlenther Onkol 2005;181:197-204.
    • (2005) Strahlenther Onkol , vol.181 , pp. 197-204
    • Burdak-Rothkamm, S.1    Rübe, C.E.2    Nguyen, T.P.3
  • 19
    • 17144371349 scopus 로고    scopus 로고
    • Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva)
    • Chinnaiyan P, Huang S, Vallabhaneni G et al. Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva). Cancer Res 2005;65:3328-3335.
    • (2005) Cancer Res , vol.65 , pp. 3328-3335
    • Chinnaiyan, P.1    Huang, S.2    Vallabhaneni, G.3
  • 20
    • 0034084314 scopus 로고    scopus 로고
    • Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: Inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis
    • Huang SM, Harari PM. Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: Inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis. Clin Cancer Res 2000;6:2166-2174.
    • (2000) Clin Cancer Res , vol.6 , pp. 2166-2174
    • Huang, S.M.1    Harari, P.M.2
  • 21
    • 19944427144 scopus 로고    scopus 로고
    • The effects of cetuximab alone and in combination with radiation and/or chemotherapy in lung cancer
    • Raben D, Helfrich B, Chan DC et al. The effects of cetuximab alone and in combination with radiation and/or chemotherapy in lung cancer. Clin Cancer Res 2005;11:795-805.
    • (2005) Clin Cancer Res , vol.11 , pp. 795-805
    • Raben, D.1    Helfrich, B.2    Chan, D.C.3
  • 22
    • 0347928791 scopus 로고    scopus 로고
    • EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Epidermal growth factor receptor
    • Solomon B, Hagekyriakou J, Trivett MK et al. EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Epidermal growth factor receptor. Int J Radiat Oncol Biol Phys 2003;55: 713-723.
    • (2003) Int J Radiat Oncol Biol Phys , vol.55 , pp. 713-723
    • Solomon, B.1    Hagekyriakou, J.2    Trivett, M.K.3
  • 23
    • 39749129748 scopus 로고    scopus 로고
    • Gefitinib radiosensitizes non-small cell lung cancer cells by suppressing cellular DNA repair capacity
    • Tanaka T, Munshi A, Brooks C et al. Gefitinib radiosensitizes non-small cell lung cancer cells by suppressing cellular DNA repair capacity. Clin Cancer Res 2008;14:1266-1273.
    • (2008) Clin Cancer Res , vol.14 , pp. 1266-1273
    • Tanaka, T.1    Munshi, A.2    Brooks, C.3
  • 24
    • 34347223656 scopus 로고    scopus 로고
    • Somatic mutations in the tyrosine kinase domain of epidermal growth factor receptor (EGFR) abrogate EGFR-mediated radioprotection in non-small cell lung carcinoma
    • Das AK, Chen BP, Story MD, et al. Somatic mutations in the tyrosine kinase domain of epidermal growth factor receptor (EGFR) abrogate EGFR-mediated radioprotection in non-small cell lung carcinoma. Cancer Res 2007;67:5267-5274.
    • (2007) Cancer Res , vol.67 , pp. 5267-5274
    • Das, A.K.1    Chen, B.P.2    Story, M.D.3
  • 25
    • 33750339641 scopus 로고    scopus 로고
    • Non-small-cell lung cancers with kinase domain mutations in the epidermal growth factor receptor are sensitive to ionizing radiation
    • Das AK, Sato M, Story MD et al. Non-small-cell lung cancers with kinase domain mutations in the epidermal growth factor receptor are sensitive to ionizing radiation. Cancer Res 2006;66:9601-9608.
    • (2006) Cancer Res , vol.66 , pp. 9601-9608
    • Das, A.K.1    Sato, M.2    Story, M.D.3
  • 26
    • 24944497744 scopus 로고    scopus 로고
    • Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib
    • Eberhard DA, Johnson BE, Amler LC et al. Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib. J Clin Oncol 2005;23:5900-5909.
    • (2005) J Clin Oncol , vol.23 , pp. 5900-5909
    • Eberhard, D.A.1    Johnson, B.E.2    Amler, L.C.3
  • 27
    • 33746877875 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutation testing in the care of lung cancer patients
    • Sequist LV, Joshi VA, Jänne PA, et al. Epidermal growth factor receptor mutation testing in the care of lung cancer patients. Clin Cancer Res 2006; 12:4403s-4408s.
    • (2006) Clin Cancer Res , vol.12
    • Sequist, L.V.1    Joshi, V.A.2    Jänne, P.A.3
  • 28
    • 77954566882 scopus 로고    scopus 로고
    • Rapid targeted muta-tional analysis of human tumours: A clinical platform to guide personalized cancer medicine
    • Dias-Santagata D, Akhavanfard S, David SS et al. Rapid targeted muta-tional analysis of human tumours: A clinical platform to guide personalized cancer medicine. EMBO Mol Med 2010;2:146-158.
    • (2010) EMBO Mol Med , vol.2 , pp. 146-158
    • Dias-Santagata, D.1    Akhavanfard, S.2    David, S.S.3
  • 29
    • 0020396015 scopus 로고
    • Toxicity and response criteria of the Eastern Cooperative Oncology Group
    • Oken MM, Creech RH, Tormey DC, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 1982;5:649-655.
    • (1982) Am J Clin Oncol , vol.5 , pp. 649-655
    • Oken, M.M.1    Creech, R.H.2    Tormey, D.C.3
  • 30
    • 34248334736 scopus 로고    scopus 로고
    • American Joint Committee On Cancer, American Cancer Society
    • Sixth Edition. New York: Springer
    • Greene FL, American Joint Committee on Cancer, American Cancer Society. AJCC Cancer Staging Manual, Sixth Edition. New York: Springer, 2002.
    • (2002) AJCC Cancer Staging Manual
    • Greene, F.L.1
  • 31
    • 79959604760 scopus 로고    scopus 로고
    • The influence of epidermal growth factor receptor mutation on the outcomes of NSCLC patients after radiotherapy
    • Pang Q, Komaki R, Lopez Guerra JL et al. The influence of epidermal growth factor receptor mutation on the outcomes of NSCLC patients after radiotherapy. J Thorac Oncol 2010;5:S509.
    • (2010) J Thorac Oncol , vol.5
    • Pang, Q.1    Komaki, R.2    Lopez Guerra, J.L.3
  • 32
    • 77954085152 scopus 로고    scopus 로고
    • Influence of smoking status on treatment outcomes after post-operative radiation therapy for non-small-cell lung cancer
    • Nguyen SK, Masson-Côté L, Fortin A et al. Influence of smoking status on treatment outcomes after post-operative radiation therapy for non-small-cell lung cancer. Radiother Oncol 2010;96:89-93.
    • (2010) Radiother Oncol , vol.96 , pp. 89-93
    • Nguyen, S.K.1    Masson-Côté, L.2    Fortin, A.3
  • 33
    • 77951880386 scopus 로고    scopus 로고
    • Performance status and smoking status are independent favorable prognostic factors for survival in non-small cell lung cancer: A comprehensive analysis of 26,957 patients with NSCLC
    • Kawaguchi T, Takada M, Kubo A et al. Performance status and smoking status are independent favorable prognostic factors for survival in non-small cell lung cancer: A comprehensive analysis of 26,957 patients with NSCLC. J Thorac Oncol 2010;5:620-630.
    • (2010) J Thorac Oncol , vol.5 , pp. 620-630
    • Kawaguchi, T.1    Takada, M.2    Kubo, A.3
  • 34
    • 33947498978 scopus 로고    scopus 로고
    • Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer
    • Sequist LV, Bell DW, Lynch TJ et al. Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer. J Clin Oncol 2007;25:587-595.
    • (2007) J Clin Oncol , vol.25 , pp. 587-595
    • Sequist, L.V.1    Bell, D.W.2    Lynch, T.J.3
  • 35
    • 33846444010 scopus 로고    scopus 로고
    • Responseto treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing
    • Sequist LV, Joshi VA, Jänne PA, et al. Responseto treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing. The Oncologist 2007;12:90-98.
    • (2007) The Oncologist , vol.12 , pp. 90-98
    • Sequist, L.V.1    Joshi, V.A.2    Jänne, P.A.3
  • 36
    • 78651083043 scopus 로고    scopus 로고
    • A phase III randomized, double-blind, placebo-controlled trial of the epidermal growth factor receptor inhibitor gefitinib in completely resected stage IB-IIIA non-small cell lung cancer (NSCLC): NCIC CTG BR.19
    • Goss GD, Lorimer I, Tsao MS, et al. A phase III randomized, double-blind, placebo-controlled trial of the epidermal growth factor receptor inhibitor gefitinib in completely resected stage IB-IIIA non-small cell lung cancer (NSCLC): NCIC CTG BR.19. J Clin Oncol 2010;28:LBA7005.
    • (2010) J Clin Oncol , vol.28
    • Goss, G.D.1    Lorimer, I.2    Tsao, M.S.3


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