Nanosized TiO2 caused minor airflow limitation in the murine airways

Archives of Toxicology

Volumn 85, Issue 7, 2011, Pages 827-839

  Leppänen, Maija ^a   Korpi, Anne ^a   Miettinen, Mirella ^a   Leskinen, Jani ^a   Torvela, Tiina ^a   Rossi, Elina M ^b   Vanhala, Esa ^b   Wolff, Henrik ^b   Alenius, Harri ^b   Kosma, Veli Matti ^a,c   Joutsensaari, Jorma ^a   Jokiniemi, Jorma ^a,d   Pasanen, Pertti ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^c KUOPIO UNIVERSITY HOSPITAL   (Finland)

^d VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

Author keywords

Airflow limitation; Engineered nanoparticles; Inflammation; Irritation; Titanium dioxide

Indexed keywords

NANOPARTICLE; NITRIC DIOXIDE; OXIDE; PROPANE; TITANIUM DIOXIDE NANOPARTICLE; UNCLASSIFIED DRUG; AGENTS ACTING ON THE PERIPHERAL NERVOUS AND NEUROMUSCULAR SYSTEMS; ALKENE; CARBON MONOXIDE; IRRITANT AGENT; METAL NANOPARTICLE; NITRIC OXIDE; PROPYLENE; TITANIUM; TITANIUM DIOXIDE;

AIRWAY CONDUCTANCE; AIRWAY OBSTRUCTION; ANIMAL EXPERIMENT; ARTICLE; BIOASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; EXPIRATORY FLOW; EXPOSURE; LUNG ALVEOLUS MACROPHAGE; LUNG DISEASE; LUNG IRRITATION; MALE; MOUSE; NANOTOXICOLOGY; NONHUMAN; PARTICLE SIZE; PNEUMONIA; PRIORITY JOURNAL; TOXICITY TESTING; AEROSOL; ANIMAL; CELL MEMBRANE PERMEABILITY; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; IMMUNOLOGY; LUNG VENTILATION; MATERIALS TESTING; METABOLISM; OUTBRED STRAIN; PH; RESPIRATORY SYSTEM; ULTRASTRUCTURE;

MURINAE;

AEROSOLS; ALKENES; ANIMALS; ANIMALS, OUTBRED STRAINS; CARBON MONOXIDE; CELL MEMBRANE PERMEABILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROGEN-ION CONCENTRATION; IRRITANTS; MACROPHAGES, ALVEOLAR; MALE; MATERIALS TESTING; METAL NANOPARTICLES; MICE; NITRIC OXIDE; PARTICLE SIZE; PULMONARY VENTILATION; RESPIRATORY SYSTEM; SENSORY SYSTEM AGENTS; TITANIUM;

EID: 79959576956     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0644-y     Document Type: Article

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