Plasma transforming growth factor β1 as a predictor of radiation pneumonitis

International Journal of Radiation Oncology Biology Physics

Volumn 41, Issue 5, 1998, Pages 1029-1035

  Anscher, Mitchell S ^a   Kong, Feng Ming ^a   Andrews, Katrina ^a   Clough, Robert ^a   Marks, Lawrence B ^a   Bentel, Gunilla ^a   Jirtle, Randy L ^a  

^a DUKE CANCER INSTITUTE   (United States)

Author keywords

Complications; Fibrosis; Growth factors; Lung cancer; Radiation therapy

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIATION DOSE; RADIATION PNEUMONIA; STATISTICAL ANALYSIS; TREATMENT PLANNING;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RADIATION PNEUMONITIS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0032527651     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(98)00154-0     Document Type: Article

References (33)

1. Emami B., Lyman J., Brown A., Coia L., Goitein M., Munzenrider J.E., Shank B., Solin L.J., Wesson M. Tolerance of normal tissue to therapeutic irradiation. Int. J. Radiat. Oncol. Biol. Phys. 21:1991;109-122.
2. King S.C., Acker J.A., Kussin P.S., Marks L.B., Weeks K.J., Leopold K.A. High-dose, hyperfractionated, accelerated radiotherapy using a concurrent boost for the treatment of nonsmall cell lung cancer unusual toxicity and promising early results . Int. J. Radiat. Oncol. Biol. Phys. 36:1996;593-599.
3. Leibel S.A. Three-dimensional conformal radiation therapy in localized carcinoma of the prostate Interim report of a phase I dose-escalation study . Int. J. Radiat. Oncol. Biol. Phys. 31:1994;1792-1798.
4. Kutcher G.J., Burman C. Calculation of complication probability factors for non-uniform normal tissue irradiation The effective volume method . Int. J. Radiat. Oncol. Biol. Phys. 21:1991;137-146.
5. Lyman J.T., Wolbarst A.V. Optimization of radiation therapy III. A method of assessing complication probabilities from dose-volume histograms. Int. J. Radiat. Oncol. Biol. Phys. 13:1987;103-109.
6. Rubin P., Finkelstein J.N., Shapiro D. Molecular biology mechanisms in the radiation induction of pulmonary injury syndromes Interrelationship between the alveolar macrophage and the septal fibroblast . Int. J. Radiat. Oncol. Biol. Phys. 24:1992;93-101.
7. Anscher M.S., Peters W.P., Reisenbichler H., Petros W.P., Jirtle R.L. Transforming growth factor β as a predictor of liver and lung fibrosis after autologous bone marrow transplantation for advanced breast cancer. N. Engl. J. Med. 328:1993;1592-1598.
8. Anscher M.S., Kong F.-M., Marks L.B., Bentel G.C., Jirtle R.L. Changes in plasma transforming growth factor beta during radiotherapy and the risk of symptomatic radiation-induced pneumonitis. Int. J. Radiat. Oncol. Biol. Phys. 37:1997;253-258.
9. Border W.A., Ruoslahti E. Transforming growth factor-β in disease The dark side of tissue repair . J. Clin. Invest. 90:1992;1-7.
10. Canney P.A., Dean S. Transforming growth factor β A promotor of late connective tissue injury following radiotherapy? Br. J. Radiol. 63:1991;620-623.
11. Edwards D.R., Murphy G., Reynolds J.J., Whitham S.E., Doherty A.J.P., Angel P., Heath J.K. Transforming growth factor β modulates the expression of collagenase and metalloproteinase inhibitor. EMBO. J. 6:1987;1899-1904.
12. Keski-Oja J.R., Raghow R., Sawdey M., Loskutoff D.J., Postlewaite A.E., Kang A.H., Moses H.L. Regulation of mRNAs for type I plasminogen activator inhibitor, fibronectin, and type I procollagen by transforming growth factor-β J. Biol. Chem. 263:1988;3111-3115.
13. Yamauchi K., Martinet Y., Basset P., Fells G.A., Crystal R.G. High levels of transforming growth factor-β are present in the epithelial fluid of the normal human lower respiratory tract. Am. Rev. Respir. Dis. 137:1988;1360-1363.
14. Broekelmann T.J., Limper A.H., Colby T.V., McDonald J.A. Transforming growth factor beta-1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc. Natl. Acad. Sci. USA. 88:1991;6642-6646.
15. Khalil N., O'Connor R.N., Unruh H.W., Warren P.W., Flanders K.C., Kemp A., Bereznay O.H., Greenberg A.H. Increased production and immunohistochemical localization of transforming growth factor-β in idiopathic pulmonary fibrosis. Am. J. Respir. Cell. Mol. Biol. 5:1991;155-162.
16. Assoian R.K., Fleurdelys B.E., Stevenson H.C., Miller P.J., Madtes D.K., Raines E.W., Ross R., Sporn M.B. Expression and secretion of transforming growth factor-β by activated human macrophages. Proc. Natl. Acad. Sci. USA. 84:1987;6020-6024.
17. Sacco O., Romberger D., Rizzino A., Beckmann J.D., Rennard S.I., Spurzem J.R. Spontaneous production of transforming growth factor-β2 by primary cultures of bronchial epithelial cells. J. Clin. Invest. 90:1992;1379-1385.
18. Anscher M.S., Murase T., Prescott D.M., Marks L.B., Reisenbichler H., Bentel G.C., Spencer D., Sherouse G., Jirtle R.L. Changes in plasma TGF-β levels during pulmonary radiotherapy as a predictor of the risk of developing radiation pneumonitis. Int. J. Radiat. Oncol. Biol. Phys. 30:1994;671-676.
19. Boersma L.J., Damen E.M., de Boer R.W., Muller S.H., Valdes Olmos R.A., van Zandwijk N., Lebesque J.V. Estimation of overall pulmonary function after irradiation using dose-effect relations for local functional injury. Radiother. Oncol. 36:1995;15-23.
20. Marks L.B., Spencer D.P., Bentel G.C., Sherouse G.W., Ray S., Sontag M., Coleman R.E., Jaszczak R.J., Turkington T.G., Tapson V., Prosnitz L.R. The utility of SPECT lung perfusion scans in minimizing and assessing the physiologic consequences of thoracic irradiation. Int. J. Radiat. Oncol. Biol. Phys. 26:1993;659-668.
21. Roberts A.B., Lamb L.C., Newton D.L., Sporn M.B., De Larco J.E., Todaro G.J. Transforming growth factors Isolation of polypeptides from virally and chemically transformed cells by acid/ethanol extraction . Proc. Natl. Acad. Sci. USA. 77:1980;3494-3498.
22. Groen H.J.M., van Waarden M., Fokkema E., van der Leest A.H.D., Konings A.W.T., Vujaskovic Z. Plasma TGF-β levels during radiotherapy with or without carboplatin predicts pneumonitis in stage III non-small cell lung cancer. Proceedings AACR. 38:1997;330.
23. Anscher M.S., Crocker I.R., Jirtle R.L. Transforming growth factor-β1 expression in irradiated liver. Radiat Res. 122:1990;77-85.
24. Finkelstein J., Johnston C., Baggs R., Rubin P. Early alteration in extracellular matrix and transforming growth factor β gene expression in mouse lung indicative of late radiation fibrosis. Int. J. Radiat. Oncol. Biol. Phys. 28:1994;621-631.
25. Hoyt B., Lazo J. Alterations in pulmonary mRNA encoding procollagens, fibronectin, and transforming growth factor beta precede bleomycin-induced pulmonary fibrosis. J. Pharmacol. Exper. Therap. 246:1988;765-771.
26. Hoyt B., Lazo J. Early increases in pulmonary mRNA encoding procollagens and transforming growth factor beta in mice sensitive to cyclophosphamide-induced pulmonary fibrosis. J. Pharmacol. Exper. Therap. 249:1989;38-43.
27. Kong F.-M., Washington M.K., Jirtle R.L., Anscher M.S. Plasma transforming growth factor β1 reflects disease status in patients with lung cancer after radiotherapy A possible tumor marker . Lung Cancer. 16:1996;47-59.
28. Kong F.M., Anscher M.S., Abbott B., Murase T., Iglehart J.D., Jirtle R.L. Elevated plasma TGFβ1 levels in breast cancer patients decrease following removal of the tumor. Ann. Surg. 222:1995;155-162.
29. Anscher M.S., Kong F.-M., Murase T., Jirtle R.L. Normal tissue injury after cancer therapy is a local manifestation of a systemic condition. Brit. J. Radiol. 68:1995;331-333.
30. Kankaki T., Olofsson A., Moren A., Wernstedt C., Hellman U., Miyazono K., Claesson-Welsh L., Heldin C.-H. TGF-β1 binding protein A component of the large latent complex of TGF-β1 with multiple repeat sequences . Cell. 61:1990;1051-1061.
31. Lyons R.M., Gentry L.E., Purchio A.F., Moses H.L. Mechanism of activation of latent recombinant transforming growth factor β1 by plasmin. J. Cell Biol. 110:1990;1361-1367.
32. Barcellos-Hoff, M. H. Redox mechanisms for activation of latent TGF-β. 43rd Annual Meeting of the Radiation Research Society, p. 153; 1995.
33. Letterio J.J., Geiser A.G., Kulkarni A.B., Roche N.S., Sporn M.B., Roberts A.B. Maternal rescue of transforming growth factor-β1 null mice. Science. 264:1994;1936-1938.