Activated microglia are the principal glial source of thromboxane in the central nervous system

Neurochemistry International

Volumn 29, Issue 1, 1996, Pages 65-76

  Giulian, Dana ^a   Corpuz, Margaret ^a   Richmond, Brian ^a   Wendt, Elaine ^a   Hall, Elizabeth R ^b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b Winstead Sechrest and Minck PC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPOLYSACCHARIDE; SUBSTANCE P; THROMBOCYTE ACTIVATING FACTOR; THROMBOXANE; THROMBOXANE B2; THROMBOXANE SYNTHASE;

ANIMAL CELL; ARTICLE; BRAIN BLOOD FLOW; BRAIN INJURY; CELL CULTURE; CENTRAL NERVOUS SYSTEM; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; GLIA; MICROGLIA; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; RAT;

EID: 0030199288     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/0197-0186(95)00140-9     Document Type: Article

References (38)

1. Abdel-Halim M.S., Lunden I., Cseh G., Anggard E. Prostaglandin profiles in nervous tissue and blood vessels of the brain of various animals. Prostaglandins. 19:1980;249-258.
2. Bashi I., Coceani F. Eicosanoid formation in the rat cerebral cortex. Molec. Chem. Neuropathol. 17:1992;219-236.
3. Bohlen P.S., Sten S., Dairman W., Udenfriend S. Fluorometric assay of proteins in the nanogram range. Arch. Biochem. Biophys. 155:1973;213-220.
4. Bottenstein J.E., Sato G.H. Growth of rat neuroblastoma cell line in serum-free supplemental medium. Proc. natn. Acad. Sci. U.S.A. 76:1979;514-517.
5. Chen S.T., Hsu C.Y., Hogen E.L., Halnshkego O., Linct I., Yatsu F.M. Thromboxane, prostaglandins, and leukotrienes in cerebral ischemia. Neurology. 36:1986;466-470.
6. Daems W.T. (1980) Peritoneal macrophages. In: The Reticuloendothelial System (Carr I. and Daems W. T. (eds), 1st edn, pp. 57-127. Plenum, New York.
7. Dubois J.H., Botta C., Cuzner R.L. The production of prostaglandin and the regulated cell division in neonate rat primary mixed glial cultures. J. Neuroimmunol. 11:1986;277-285.
8. Fontana A., Kristesser F., Dubs R., Gensa D., Weber E. Production of prostaglandin E and interleukin-1-like factor by cultured astrocytes and C6 glioma cells. J. Immunol. 129:1982;2413-2419.
9. Giulian D. Ameboid microglia as effectors of inflammation in the central nervous system. J. Neurosci. Res. 18:1987;155-171.
10. Giulian D. Microglia and disease of the nervous system. Curr. Topics Neurol. 12:1992;23-54.
11. Giulian D., Baker T.J. Characterization of ameboid microglia isolated from developing mammalian brain. J. Neurosci. 6:1986;2163-2178.
12. Giulian D., Chen J., George J., Noponen M. The role of mononuclear phagocytes in wound healing after traumatic injury to the adult mammalian brain. J. Neurosci. 9:1991;4416-4429.
13. Giulian D., Johnson B., Krebs J.F., George J.K., Tapscott M. Microglial mitogens are produced in the developing and injured mammalian brain. J. Cell Biol. 112:1991;323-333.
14. Giulian D., Lachman L.B. IL -1 stimulates astroglial growth after brain injury. Science. 228:1985;497-499.
15. Giulian D., Vaca K., Corpuz M. Brain glia release factors with opposing actions upon neuronal survival. J. Neurosci. 13:1993;29-37.
16. 2. Its use in solid and liquid phase radioimmunoassays. Prostaglandins Leukotrienes Med. 30:1987;103-109.
17. Hall E.R., Tai H.H. Purification of thromboxane synthase and evidence of two distinct mechanisms for the formation of 12-L-hydroxy-5,8,10-heptadecatrienoic acid by porcine lung microsomes. Biochim. Biophys. Acta. 665:1981;498-503.
18. 2 inactivates purified human platelet thromboxane synthase. Biochem. J. 233:1986;637-641.
19. Hartung H.P., Heininger K., Schafter B., Toyka K.V. Substance P stimulation and astrocytes: stimulation of cyclooxygenase pathway of arachidonic acid metabolism. FASEB J. 2:1988;48-65.
20. Hartung H.P., Schafter B., Heininger K. And Tokya K. V. Recombinant interleukin 1 β stimulates eicosanoid production in rat primary culture astrocytes. Brain Res. 489:1989;113-119.
21. Jacobs T.P., Shohami E., Baze W., Burgard E., Gunderson C., Hallenbeck J.M., Feuerstein G. Deteriorating stroke model: histopathology, edema, and eicosanoid changes following spinal cord ischemia in rabbits. Stroke. 18:1987;741-750.
22. Katzung B.G. (ed.) (1989) In: The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes and Related Compounds. Basic and Clinical Pharmacology, 4th edn, pp. 228-241.
23. Keller M., Jackisch R., Seregi A., Hertting G. Comparison of prostanoid forming capacity of neuronal and astroglial cells in primary culture. Neurochem. Int. 7:1985;655-665.
24. Murphy S., Jeremy K., Pearce B., Dandona P. Eicosanoid synthesis and release from primary cultures of rat central nervous system astrocytes and meningeal cells. Neurosci. Lett. 61:1985;61-65.
25. Nathan C., Murray H. and Cohen Z. (1980) Concept of activated macrophage. New Engl. J. Med. 303, 42-44, 622-625.
26. 2 in rat cultured astrocytes. J. Biol. Chem. 226:1991;9956-9960.
27. 2+ mobilization and prostanoid release from astrocytes: P2-purinergic receptors linked to phosphoinositide hydrolysis. J. Neurochem. 52:1989;971-977.
28. Pettigrew L.C., Misra L.K., Grotta J.C., Narayana P.A., Wu K.K. Selective inhibition of thromboxane synthase enhances reperfusion and metabolism of the ischemic brain. Ann N.Y. Acad. Sci. 559:1989;478-479.
29. Rio Hortega P. del (1932) Microglia. In: Cytology and Cellular Pathology of the Nervous System (Penfield W., ed.) pp. 481-584. Hoeben, New York.
30. 3 direct chemical-ionization mass spectometry of underivatized prostaglandin-H2 and other selected stable prostaglandins. Biomed. Envir. Mass Spect. 13:1986;545-551.
31. Seregi A., Keller M., Hertting G. Are cerebral prostanoids of astroglial origin? Studies on the prostanoid forming system in developing rat brain and primary cultures of rat astrocytes. Brain Res. 404:1987;113-120.
32. Shimizu T., Wolfe L.S. Arachidonic acid cascade and signal transduction. J. Neurochem. 55:1990;1-15.
33. 2 and 5-hete production following spinal cord ischemia in the rabbit. Prost. Leuko. Med. 28:1987;167-181.
34. Tokiyoshi K., Ohnishi T., Nii Y. Efficacy and toxicity of thromboxane synthase inhibitor of cerebral vasospasm after subarchnoid hemorrhage. Surg. Neurol. 36:1991;112-118.
35. Westscott J.Y., Murphy R.C., Stenmark K. Eicosanoid in human ventricular cerebrospinal fluid following severe brain injury. Prostaglandins. 34:1987;877-887.
36. Wolfe L.S., Coceani F. The role of prostaglandins in the CNS. Ann. Rev. Physiol. 41:1979;669-984.
37. 2 by brain tissue. Biochem. Biophys. Res. Commun. 70:1976;907-913.
38. 2 using a nonaqueous bonded-phase HPLC system. Anal. Biochem. 154:1986;152-161.