LFR1 ferric iron reductase of Leishmania amazonensis is essential for the generation of infective parasite forms

Journal of Biological Chemistry

Volumn 286, Issue 26, 2011, Pages 23266-23279

  Flannery, Andrew R ^a   Huynh, Chau ^a   Mittra, Bidyottam ^a   Mortara, Renato A ^b   Andrews, Norma W ^a  

^a Bldg 142   (United States)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ABNORMAL MORPHOLOGY; CAUSATIVE AGENTS; FERRIC IRON; FERRIC REDUCTASE; FERROUS IRON; GROWTH DEFECTS; HUMAN INFECTION; INTRACELLULAR TRANSPORT; IRON ACQUISITION; IRON UPTAKE; LEISHMANIA; NULL MUTANT; OVER-EXPRESSION; PARASITE-; PROMASTIGOTES; PROTOZOAN PARASITES;

CELL MEMBRANES; ENZYME ACTIVITY; GENES; MACROPHAGES;

IRON;

CARRIER PROTEIN; FERRIC REDUCTASE 1; IRON; IRON TRANSPORTER; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE OVEREXPRESSION; INTRACELLULAR TRANSPORT; IRON DEPLETION; LEISHMANIA; LEISHMANIA CHAGASI; LEISHMANIA DONOVANI; LEISHMANIA INFANTUM; LEISHMANIA MAJOR; LFR1 GENE; LIT1 GENE; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE DEVELOPMENT; PARASITE VIABILITY; PARASITE VIRULENCE; PRIORITY JOURNAL; PROMASTIGOTE; UPREGULATION;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; FMN REDUCTASE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; IRON; LEISHMANIA; LEISHMANIASIS; MACROPHAGES; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PROTOZOAN PROTEINS;

HEXAPODA; LEISHMANIA AMAZONENSIS; PROTOZOA; VERTEBRATA;

EID: 79959535754     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.229674     Document Type: Article

References (46)

1. Sacks, D., and Kamhawi, S. (2001) Annu. Rev. Microbiol. 55, 453-483
2. Morris, C. J., Earl, J. R., Trenam, C. W., and Blake, D. R. (1995) Int. J. Biochem. Cell Biol. 27, 109-122
3. Imlay, J. A., Chin, S. M., and Linn, S. (1988) Science 240, 640-642
4. Askwith, C. C., de Silva, D., and Kaplan, J. (1996) Mol. Microbiol. 20, 27-34
5. Wu, H., Li, L., Du, J., Yuan, Y., Cheng, X., and Ling, H. Q. (2005) Plant Cell Physiol. 46, 1505-1514
6. Huynh, C., and Andrews, N. W. (2008) Cell. Microbiol. 10, 293-300
7. Huynh, C., Sacks, D. L., and Andrews, N. W. (2006) J. Exp. Med. 203, 2363-2375
8. Jacques, I., Andrews, N. W., and Huynh, C. (2010) Mol. Biochem. Parasitol. 170, 28-36
9. Wilson, M. E., Lewis, T. S., Miller, M. A., McCormick, M. L., and Britigan, B. E. (2002) Exp. Parasitol. 100, 196-207
10. Courret, N., Prina, E., Mougneau, E., Saraiva, E. M., Sacks, D. L., Glaichenhaus, N., and Antoine, J. C. (1999) Eur. J. Immunol. 29, 762-773
11. Pinto-da-Silva, L. H., Fampa, P., Soares, D. C., Oliveira, S. M., Souto-Padron, T., and Saraiva, E. M. (2005) Int. J. Parasitol. 35, 757-764
12. Medina-Acosta, E., and Cross, G. A. (1993) Mol. Biochem. Parasitol. 59, 327-329
13. Marchler-Bauer, A., Anderson, J. B., Chitsaz, F., Derbyshire, M. K., DeWeese-Scott, C., Fong, J. H., Geer, L. Y., Geer, R. C., Gonzales, N. R., Gwadz, M., He, S., Hurwitz, D. I., Jackson, J. D., Ke, Z., Lanczycki, C. J., Liebert, C. A., Liu, C., Lu, F., Lu, S., Marchler, G. H., Mullokandov, M., Song, J. S., Tasneem, A., Thanki, N., Yamashita, R. A., Zhang, D., Zhang, N., and Bryant, S. H. (2009) Nucleic Acids Res. 37, D205-D210
14. Marchler-Bauer, A., and Bryant, S. H. (2004) Nucleic Acids Res. 32, W327-W331
15. Hirokawa, T., Boon-Chieng, S., and Mitaku, S. (1998) Bioinformatics 14, 378-379
16. Chenna, R., Sugawara, H., Koike, T., Lopez, R., Gibson, T. J., Higgins, D. G., and Thompson, J. D. (2003) Nucleic Acids Res. 31, 3497-3500
17. Ha, D. S., Schwarz, J. K., Turco, S. J., and Beverley, S. M. (1996) Mol. Biochem. Parasitol. 77, 57-64
18. LeBowitz, J. H., Coburn, C. M., McMahon-Pratt, D., and Beverley, S. M. (1990) Proc. Natl. Acad. Sci. U.S.A. 87, 9736-9740
19. Depledge, D. P., Evans, K. J., Ivens, A. C., Aziz, N., Maroof, A., Kaye, P. M., and Smith, D. F. (2009) PLoS Negl. Trop. Dis. 3, e476
20. Rochette, A., Raymond, F., Ubeda, J. M., Smith, M., Messier, N., Boisvert, S., Rigault, P., Corbeil, J., Ouellette, M., and Papadopoulou, B. (2008)BMC Genomics 9, 255
21. Olakanmi, O., Stokes, J. B., Pathan, S., and Britigan, B. E. (1997) J. Biol. Chem. 272, 2599-2606
22. Goldberg, M. W., and Allen, T. D. (1992) J. Cell Biol. 119, 1429-1440
23. Kar, S., Soong, L., Colmenares, M., Goldsmith-Pestana, K., and McMahon-Pratt, D. (2000) J. Biol. Chem. 275, 37789-37797
24. Becker, S. M., Delamarre, L., Mellman, I., and Andrews, N. W. (2009) Immunobiology 214, 495-505
25. Tabbara, K. S., Peters, N. C., Afrin, F., Mendez, S., Bertholet, S., Belkaid, Y., and Sacks, D. L. (2005) Infect. Immun. 73, 4714-4722
26. Finn, R. D., Mistry, J., Tate, J., Coggill, P., Heger, A., Pollington, J. E., Gavin, O. L., Gunasekaran, P., Ceric, G., Forslund, K., Holm, L., Sonnhammer, E. L., Eddy, S. R., and Bateman, A. (2010) Nucleic Acids Res. 38, D211-D222
27. Dancis, A., Roman, D. G., Anderson, G. J., Hinnebusch, A. G., and Klausner, R. D. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 3869-3873
28. Waters, B. M., Blevins, D. G., and Eide, D. J. (2002) Plant Physiol. 129, 85-94
29. Schagerlöf, U., Wilson, G., Hebert, H., Al-Karadaghi, S., and Hägerhäll, C. (2006) Plant Mol. Biol. 62, 215-221
30. Finegold, A. A., Shatwell, K. P., Segal, A. W., Klausner, R. D., and Dancis, A. (1996) J. Biol. Chem. 271, 31021-31024
31. Sacks, D. L., and Perkins, P. V. (1984) Science 223, 1417-1419
32. Hodgkinson, V. H., Soong, L., Duboise, S. M., and McMahon-Pratt, D. (1996) Exp. Parasitol. 83, 94-105
33. Titus, R. G., Marchand, M., Boon, T., and Louis, J. A. (1985) Parasite Immunol. 7, 545-555
34. Anderson, E., and Batten, B. E. (1983) Tissue Cell 15, 853-871
35. Radisky, D. C., and Kaplan, J. (1998) Biochem. J. 336, 201-205
36. Chang, C. S., and Chang, K. P. (1985) Mol. Biochem. Parasitol. 16, 267-276
37. Segovia, M., Navarro, A., and Artero, J. M. (1989) Ann. Trop. Med. Parasitol. 83, 357-360
38. Sengupta, S., Tripathi, J., Tandon, R., Raje, M., Roy, R. P., Basu, S. K., and Mukhopadhyay, A. (1999) J. Biol. Chem. 274, 2758-2765
39. Soteriadou, K., Papavassiliou, P., Voyiatzaki, C., and Boelaert, J. (1995) J. Antimicrob. Chemother. 35, 23-29
40. Wilson, M. E., Vorhies, R. W., Andersen, K. A., and Britigan, B. E. (1994) Infect. Immun. 62, 3262-3269
41. Sumimoto, H. (2008) FEBS J. 275, 3249-3277
42. Cross, A. R., and Segal, A. W. (2004) Biochim. Biophys. Acta 1657, 1-22
43. Anderson, G. J., Lesuisse, E., Dancis, A., Roman, D. G., Labbe, P., and Klausner, R. D. (1992) J. Inorg. Biochem. 47, 249-255
44. Shatwell, K. P., Dancis, A., Cross, A. R., Klausner, R. D., and Segal, A. W. (1996) J. Biol. Chem. 271, 14240-14244
45. Vasconcelos, M., Eckert, H., Arahana, V., Graef, G., Grusak, M. A., and Clemente, T. (2006) Planta 224, 1116-1128
46. Zhang, D. L., Su, D., Bérczi, A., Vargas, A., and Asard, H. (2006) Biochim. Biophys. Acta 1760, 1903-1913