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Volumn 106, Issue 40, 2009, Pages 16956-16961

Orthogonal analytical approaches to detect potential contaminants in heparin

Author keywords

Anticoagulant; Capillary electrophoresis; Contamination; NMR; Oversulfated chondroitin

Indexed keywords

CHONDROITIN SULFATE; HEPARIN; POLYSACCHARIDE;

EID: 70350133604     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0906861106     Document Type: Article
Times cited : (91)

References (41)
  • 1
    • 0038792320 scopus 로고    scopus 로고
    • 2003 Claude S. Hudson Award address in carbohydrate chemistry. Heparin: Structure and activity
    • Linhardt RJ (2003) 2003 Claude S. Hudson Award address in carbohydrate chemistry. Heparin: Structure and activity. J Med Chem 46:2551-2564.
    • (2003) J Med Chem , vol.46 , pp. 2551-2564
    • Linhardt, R.J.1
  • 2
    • 0035707396 scopus 로고    scopus 로고
    • Structure and biological interactions of heparin and heparan sulfate
    • DOI 10.1016/S0065-2318(01)57017-1
    • Casu B, Lindahl U (2001) Structure and biological interactions of heparin and heparan sulfate. Adv Carbohydr Chem Biochem 57:159-206. (Pubitemid 34121000)
    • (2001) Advances in Carbohydrate Chemistry and Biochemistry , vol.57 , pp. 159-206
    • Casu, B.1    Lindahl, U.2
  • 3
    • 0032745131 scopus 로고    scopus 로고
    • Production and chemical processing of low molecular weight heparins
    • Linhardt RJ, Gunay NS (1999) Production and chemical processing of low molecular weight heparins. Semin Thromb Hemost 25:5-16. (Pubitemid 29517028)
    • (1999) Seminars in Thrombosis and Hemostasis , vol.25 , Issue.4 SUPPL. 3 , pp. 5-16
    • Linhardt, R.J.1    Gunay, N.S.2
  • 4
    • 61449171129 scopus 로고    scopus 로고
    • Lessons learned from the contamination of heparin
    • Liu H, Zhang Z, Linhardt RJ (2009) Lessons learned from the contamination of heparin. Nat Prod Rep 26:313-321.
    • (2009) Nat Prod Rep , vol.26 , pp. 313-321
    • Liu, H.1    Zhang, Z.2    Linhardt, R.J.3
  • 5
    • 0028788196 scopus 로고
    • Isolation and characterization of heparan sulfate from crude porcine intestinal mucosal peptidoglycan heparin
    • Griffin CC, et al. (1995) Isolation and characterization of heparan sulfate from crude porcine intestinal mucosal peptidoglycan heparin. Carbohydr Res 276:183-197.
    • (1995) Carbohydr Res , vol.276 , pp. 183-197
    • Griffin, C.C.1
  • 7
    • 0027906282 scopus 로고
    • "Fast moving" and "slow moving" heparins, dermatan sulfate, and chondroitin sulfate: Qualitative and quantitative analysis by agarose-gel electrophoresis
    • Volpi N (1993) "Fast moving" and "slow moving" heparins, dermatan sulfate, and chondroitin sulfate: Qualitative and quantitative analysis by agarose-gel electrophoresis. Carbohydr Res 247:263-278.
    • (1993) Carbohydr Res , vol.247 , pp. 263-278
    • Volpi, N.1
  • 8
    • 0022365027 scopus 로고
    • Fractionation and structural features of two heparin families with high antithrombotic, antilipemic and anticoagulant activities
    • Bianchini P, et al. (1985) Fractionation and structural features of two heparin families with high antithrombotic, antilipemic and anticoagulant activities. Arzneimittelforschung 35:1215-1219. (Pubitemid 16240616)
    • (1985) Arzneimittel-Forschung/Drug Research , vol.35 , Issue.8 , pp. 1215-1219
    • Bianchini, P.1    Osima, B.2    Parma, B.3
  • 11
    • 70349648765 scopus 로고    scopus 로고
    • Analysis of pharmaceutical heparins and potential contaminants using 1H-NMR and PAGE
    • 10.1002/jsp.21729
    • Zhang Z, et al. (2009) Analysis of pharmaceutical heparins and potential contaminants using 1H-NMR and PAGE. J Pharm Science, 10.1002/jsp.21729.
    • (2009) J Pharm Science
    • Zhang, Z.1
  • 14
    • 58049216683 scopus 로고    scopus 로고
    • Outbreak of adverse reactions associated with contaminated heparin
    • Blossom DB, et al. (2008) Outbreak of adverse reactions associated with contaminated heparin. N Engl J Med 359:2674-2684.
    • (2008) N Engl J Med , vol.359 , pp. 2674-2684
    • Blossom, D.B.1
  • 15
    • 0026583305 scopus 로고
    • Patterns of sulphation in heparan sulphate: Polymorphism based on a common structural theme
    • Gallagher JT, Turnbull JE, Lyon M (1992) Patterns of sulphation in heparan sulphate: Polymorphism based on a common structural theme. Int J Biochem 24:553-560.
    • (1992) Int J Biochem , vol.24 , pp. 553-560
    • Gallagher, J.T.1    Turnbull, J.E.2    Lyon, M.3
  • 17
    • 11844269975 scopus 로고    scopus 로고
    • Complex glycosaminoglycans: Profiling substitution patterns by two-dimensional nuclear magnetic resonance spectroscopy
    • DOI 10.1016/j.ab.2004.10.012, PII S0003269704008152
    • Guerrini M, Naggi A, Guglieri S, Santarsiero R, Torri G (2005) Complex glycosaminoglycans: Profiling substitution patterns by two-dimensional nuclear magnetic resonance spectroscopy. Anal Biochem 337:35-47. (Pubitemid 40092776)
    • (2005) Analytical Biochemistry , vol.337 , Issue.1 , pp. 35-47
    • Guerrini, M.1    Naggi, A.2    Guglieri, S.3    Santarsiero, R.4    Torri, G.5
  • 19
    • 0031799877 scopus 로고    scopus 로고
    • Conformational changes and anticoagulant activity of chondroitin sulfate following its O-sulfonation
    • DOI 10.1016/S0008-6215(97)10060-X, PII S000862159710060X
    • Maruyama T, Toida T, Imanari T, Yu G, Linhardt RJ (1998) Conformational changes and anticoagulant activity of chondroitin sulfate following its O-sulfonation. Carbohydr Res 306:35-43. (Pubitemid 28304973)
    • (1998) Carbohydrate Research , vol.306 , Issue.1-2 , pp. 35-43
    • Maruyama, T.1    Toida, T.2    Imanari, T.3    Yu, G.4    Linhardt, R.J.5
  • 21
    • 0034693310 scopus 로고    scopus 로고
    • Effect of substitution pattern on 1H, 13CNMRchemical shifts and 1J(CH) coupling constants in heparin derivatives
    • Yates EA, et al. (2000) Effect of substitution pattern on 1H, 13CNMRchemical shifts and 1J(CH) coupling constants in heparin derivatives. Carbohydr Res 329:239-247.
    • (2000) Carbohydr Res , vol.329 , pp. 239-247
    • Yates, E.A.1
  • 22
    • 34547097276 scopus 로고    scopus 로고
    • Low molecular weight heparins: Structural differentiation by bidimensional nuclear magnetic resonance spectroscopy
    • Guerrini M, Guglieri S, Naggi A, Sasisekharan R, Torri G (2007) Low molecular weight heparins: Structural differentiation by bidimensional nuclear magnetic resonance spectroscopy. Semin Thromb Hemost 33:478-487.
    • (2007) Semin Thromb Hemost , vol.33 , pp. 478-487
    • Guerrini, M.1    Guglieri, S.2    Naggi, A.3    Sasisekharan, R.4    Torri, G.5
  • 24
    • 62949143587 scopus 로고    scopus 로고
    • Improved impurity fingerprinting of heparin by high resolution (1)H NMR spectroscopy
    • Bigler P, Brenneisen R (2009) Improved impurity fingerprinting of heparin by high resolution (1)H NMR spectroscopy. J Pharm Biomed Anal 49:1060-1064.
    • (2009) J Pharm Biomed Anal , vol.49 , pp. 1060-1064
    • Bigler, P.1    Brenneisen, R.2
  • 25
    • 49749083965 scopus 로고    scopus 로고
    • Quality assessment of unfractionated heparin using 1H nuclear magnetic resonance spectroscopy
    • Beyer T, et al. (2008) Quality assessment of unfractionated heparin using 1H nuclear magnetic resonance spectroscopy. J Pharm Biomed Anal 48:13-19.
    • (2008) J Pharm Biomed Anal , vol.48 , pp. 13-19
    • Beyer, T.1
  • 26
    • 64549149399 scopus 로고    scopus 로고
    • Source-induced fragmentation of heparin, heparan, and galactosaminoglycans and application
    • Hu P, Fang L, Chess EK (2009) Source-induced fragmentation of heparin, heparan, and galactosaminoglycans and application. Anal Chem 81:2332-2343.
    • (2009) Anal Chem , vol.81 , pp. 2332-2343
    • Hu, P.1    Fang, L.2    Chess, E.K.3
  • 27
    • 70349243167 scopus 로고    scopus 로고
    • Screening of heparin API by near infrared reflectance and Raman spectroscopy
    • 10.1002/jps.21660
    • Spencer JA, et al. (2009) Screening of heparin API by near infrared reflectance and Raman spectroscopy. J Pharm Science, 10.1002/jps.21660.
    • (2009) J Pharm Science
    • Spencer, J.A.1
  • 28
    • 65549167302 scopus 로고    scopus 로고
    • Prediction of the oversulphated chondroitin sulphate contamination of unfractionated heparin by ATR-IR spectrophotometry
    • Norwig J, et al. (2009) Prediction of the oversulphated chondroitin sulphate contamination of unfractionated heparin by ATR-IR spectrophotometry. Pharmeur Sci Notes 2009:17-24.
    • (2009) Pharmeur Sci Notes , vol.2009 , pp. 17-24
    • Norwig, J.1
  • 29
    • 59049102782 scopus 로고    scopus 로고
    • Determination of impurities in heparin by capillary electrophoresis using high molarity phosphate buffers
    • Wielgos T, Havel K, Ivanova N, Weinberger R (2009) Determination of impurities in heparin by capillary electrophoresis using high molarity phosphate buffers. J Pharm Biomed Anal 49:319-326.
    • (2009) J Pharm Biomed Anal , vol.49 , pp. 319-326
    • Wielgos, T.1    Havel, K.2    Ivanova, N.3    Weinberger, R.4
  • 30
    • 63149149990 scopus 로고    scopus 로고
    • Quantitative capillary electrophoresis determination of oversulfated chondroitin sulfate as a contaminant in heparin preparations
    • Volpi N, Maccari F, Linhardt RJ (2009) Quantitative capillary electrophoresis determination of oversulfated chondroitin sulfate as a contaminant in heparin preparations. Anal Biochem 388:140-145.
    • (2009) Anal Biochem , vol.388 , pp. 140-145
    • Volpi, N.1    Maccari, F.2    Linhardt, R.J.3
  • 31
    • 63449087810 scopus 로고    scopus 로고
    • Determination of oversulfated chondroitin sulfate and dermatan sulfate impurities in heparin by capillary electrophoresis
    • Somsen GW, Tak YH, Torano JS, Jongen PM, de Jong GJ (2009) Determination of oversulfated chondroitin sulfate and dermatan sulfate impurities in heparin by capillary electrophoresis. J Chromatogr A 1216:4107-4112.
    • (2009) J Chromatogr A , vol.1216 , pp. 4107-4112
    • Somsen, G.W.1    Tak, Y.H.2    Torano, J.S.3    Jongen, P.M.4    De Jong, G.J.5
  • 33
    • 58149121309 scopus 로고    scopus 로고
    • Detection of high-charge density polyanion contaminants in biomedical heparin preparations using potentiometric polyanion sensors
    • WangL, Buchanan S, MeyerhoffME(2008) Detection of high-charge density polyanion contaminants in biomedical heparin preparations using potentiometric polyanion sensors. Anal Chem 80:9845-9847.
    • (2008) Anal Chem , vol.80 , pp. 9845-9847
    • Wang, L.1    Buchanan, S.2    Meyerhoff, M.E.3
  • 34
    • 53649105226 scopus 로고    scopus 로고
    • Inhibition of Taq polymerase as amethod for screening heparin for oversulfated contaminants
    • Tami C, et al. (2008) Inhibition of Taq polymerase as amethod for screening heparin for oversulfated contaminants. Biomaterials 29:4808-4814.
    • (2008) Biomaterials , vol.29 , pp. 4808-4814
    • Tami, C.1
  • 35
    • 64549101987 scopus 로고    scopus 로고
    • Identification of a simple and sensitive microplate method for the detection of oversulfated chondroitin sulfate in heparin products
    • Bairstow S, McKee J, Nordhaus M, Johnson R (2009) Identification of a simple and sensitive microplate method for the detection of oversulfated chondroitin sulfate in heparin products. Anal Biochem 388:317-321.
    • (2009) Anal Biochem , vol.388 , pp. 317-321
    • Bairstow, S.1    McKee, J.2    Nordhaus, M.3    Johnson, R.4
  • 36
    • 65749088905 scopus 로고    scopus 로고
    • Oversulfated chondroitin sulfate interaction with heparin-binding proteins: New insights into adverse reactions from contaminated heparins
    • Li B, et al. (2009) Oversulfated chondroitin sulfate interaction with heparin-binding proteins: New insights into adverse reactions from contaminated heparins. Biochem Pharmacol 78:292-300.
    • (2009) Biochem Pharmacol , vol.78 , pp. 292-300
    • Li, B.1
  • 37
    • 0034771647 scopus 로고    scopus 로고
    • Toward a biotechnological heparin through combined chemical and enzymatic modification of the Escherichia coli K5 polysaccharide
    • DOI 10.1055/s-2001-17954
    • Naggi A, et al. (2001) Toward a biotechnological heparin through combined chemical and enzymatic modification of the Escherichia coli K5 polysaccharide. Semin Thromb Hemost 27:437-443. (Pubitemid 32989368)
    • (2001) Seminars in Thrombosis and Hemostasis , vol.27 , Issue.5 , pp. 437-443
    • Naggi, A.1    Torri, G.2    Casu, B.3    Oreste, P.4    Zoppetti, G.5    Li, J.P.6    Lindahl, U.7
  • 38
    • 0026428315 scopus 로고
    • Sulfation of some chemically-modified heparins. Formation of a 3-sulfate analog of heparin
    • Rej RN, Ludwig-Baxter KG, Perlin AS (1991) Sulfation of some chemically-modified heparins. Formation of a 3-sulfate analog of heparin. Carbohydr Res 210:299-310.
    • (1991) Carbohydr Res , vol.210 , pp. 299-310
    • Rej, R.N.1    Ludwig-Baxter, K.G.2    Perlin, A.S.3
  • 39
    • 0029658229 scopus 로고    scopus 로고
    • 13C NMR spectral assignments of the major sequences of twelve systematically modified heparin derivatives
    • DOI 10.1016/S0008-6215(96)00213-3, PII S0008621596002133
    • Yates EA, et al. (1996) 1H and 13C NMR spectral assignments of the major sequences of twelve systematically modified heparin derivatives. Carbohydr Res 294:15-27. (Pubitemid 26388787)
    • (1996) Carbohydrate Research , vol.294 , pp. 15-27
    • Yates, E.A.1    Santini, F.2    Guerrini, M.3    Naggi, A.4    Torri, G.5    Casu, B.6
  • 41
    • 69749122095 scopus 로고    scopus 로고
    • Isolation and characterization of contaminants in recalled unfractionated heparin and low-molecular-weight heparin
    • in press
    • Viskov C, et al. (2009) Isolation and characterization of contaminants in recalled unfractionated heparin and low-molecular-weight heparin. Clin Appl Thromb Hemost, in press.
    • (2009) Clin Appl Thromb Hemost
    • Viskov, C.1


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