Characterization of heparin impurities with HPLC-NMR using weak anion exchange chromatography

Analytical Chemistry

Volumn 81, Issue 24, 2009, Pages 10116-10123

  Limtiaco, John F K ^a   Jones, Christopher J ^a   Larive, Cynthia K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTES; ANION EXCHANGE; ANION EXCHANGE CHROMATOGRAPHY; CHONDROITIN SULFATES; CHROMATOGRAPHIC PEAKS; DERMATAN SULFATE; NMR SPECTRUM; ON-LINE SEPARATION; RAPID IDENTIFICATION; SALT CONCENTRATION; STRONG ANION-EXCHANGE CHROMATOGRAPHY; STRUCTURAL IDENTIFICATION; UV- AND;

CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMPURITIES; IONS; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SEPARATION; SOLAR CONCENTRATORS; SULFUR COMPOUNDS; SUPPLY CHAINS;

POLYSACCHARIDES;

CHONDROITIN 4 SULFATE; CHONDROITIN SULFATE; DERMATAN SULFATE; FULLY SULFATED CHONDROITIN SULFATE; HEPARIN; PROTON; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; BIOSYNTHESIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DETERMINATION; DRUG IMPURITY; ELUTION; FLOW MEASUREMENT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR PROBE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PH; PROTON NUCLEAR MAGNETIC RESONANCE; QUALITY CONTROL; SEPARATION TECHNIQUE; SULFATION; WEAK ANION EXCHANGE CHROMATOGRAPHY;

CHONDROITIN SULFATES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; DERMATAN SULFATE; HEPARIN; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY;

EID: 72449142595     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac901812y     Document Type: Article

References (36)

1. Bigler, P.; Brenneisen, R. J. Pharm. Biomed. Anal. 2009, 49, 1060-1064.
2. Rabenstein, D. Nat. Prod. Rep. 2002, 19, 312-331.
3. Guerrini, M.; Beccati, D.; Shriver, Z.; Naggi, A.; Viswanathan, K.; Bisio, A.; Capila, I.; Lansing, J. C.; Guglieri, S.; Fraser, B.; Al-Hakim, A.; Gunay, N. S.; Zhang, Z. Q.; Robinson, L.; Buhse, L.; Nasr, M.; Woodcock, J.; Langer, R.; Venkataraman, G.; Linhardt, R. J.; Casu, B.; Torri, G.; Sasisekharan, R. Nat. Biotechnol. 2008, 26, 669-675.
4. Liu, H.; Zhang, Z.; Linhardt, R. Nat. Prod. Rep. 2008, 26, 313-321.
5. Whitelock, J. M.; Iozzo, R. V. Chem. Rev. 2005, 105, 2745-2764.
6. Capila, I.; Linhardt, R. J. Angew. Chem., Int. Ed. 2002, 41, 391-412.
7. Noti, C.; Seeberger, P. H. Chem. Biol. 2005, 12, 731-756.
8. Trehy, M.; Reepmeyer, J.; Kolinski, R.; Westenberger, B.; Bushe, L. J. Pharm. Biomed. Anal. 2009, 49, 670-673.
9. Blossom, D.; Kallen, A.; Patel, P.; Elward, A.; Robinson, L.; Gao, G.; Langer, R.; Perkins, K.; Jaeger, J. New Engl. J Med. 2008, 359, 2674-2684.
10. Maruyama, T.; Toida, T.; Imanari, T.; Yu, G.; Linhardt, R. J. Carbohydr. Res. 1998, 306, 35-43.
11. Kishimoto, T. K.; Viswanathan, K.; Ganguly, T.; Elankumaran, S.; Smith, S.; Pelzer, K.; Lansing, J. C.; Sriranganathan, N.; Zhao, G. L.; Galcheva- Gargova, Z.; Al-Hakim, A.; Bailey, G. S.; Fraser, B.; Roy, S.; Rogers-Cotrone, T.; Buhse, L.; Whary, M.; Fox, J.; Nasr, M.; Dal Pan, G. J.; Shriver, Z.; Langer, R. S.; Venkataraman, G.; Austen, K. F.; Woodcock, J.; Sasisekharan, R. New Engl. J Med. 2008, 358, 2457-2467.
12. Hojima, Y.; Cochrane, C. G.; Wiggins, R. C.; Austen, K. F.; Stevens, R. L. Blood 1984, 63, 1453-1459.
13. Beyer, T.; Diehl, B.; Randel, G.; Humpfer, E.; Schäfer, H.; Spraul, M.; Schollmayer, C.; Holzgrabe, U. J. Pharm. Biomed. Anal. 2008, 48, 13-19.
14. Somsen, G. W.; Tak, Y. H.; Toraño, Y. H.; Jongen, P. M. J. M.; de Jong, G. J. Chromatogr. A 2009, 1216, 4107-4112.
15. Nagasawa, K.; Uchiyama, H.; Wajima, N. Carbohydr. Res. 1986, 158, 183-190.
16. Glasoe, P. K.; Long, F. A. J. Phys. Chem. 1960, 64, 188-190.
17. Smallcombe, S. H.; Patt, S. L.; Keifer, P. A. J. Magn. Reson., Ser. A 1995, 117, 295-303.
18. Dantus, M. M.; Wells, M. L. J. Liq. Chromatogr. Relat. Technol. 2004, 27, 1413-1442.
19. Korir, A.; Larive, C. Anal. Bioanal. Chem. 2009, 393, 155-169.
20. Korir, A. K.; Limtiaco, J. F. K.; Gutierrez, S. M.; Larive, C. K. Anal. Chem. 2008, 80, 1297-1306.
21. Eldridge, S. L.; Korir, A. K.; Gutierrez, S. M.; Campos, F.; Limtiaco, J. F. K.; Larive, C. K. Carbohydr. Res. 2008, 343, 2963-2970.
22. Huang, Y.; Toyoda, H.; Koshiishi, I.; Toida, T.; Imanari, T. Chem. Pharm. Bull. 1995, 43, 2182-2186.
23. Buchanan, D. L. Anal. Chem. 1959, 31, 833-836.
24. Ramsey, R.; Katti, A. M.; Guiochon, G. Anal. Chem. 2002, 62, 2557-2565.
25. Wielgos, T.; Havel, K.; Ivanova, N.; Weinerger, R. J. Pharm. Biomed. 2009, 49, 319-326.
26. Guerrini,M.; Naggi, A.; Guglieri, S.; Santarsiero, R.; Torri, G. Anal. Biochem. 2005, 337, 35-47.
27. Torri, G.; Guerrini, M. In NMR Spectroscopy in Pharmaceutical Analysis; Holzgrabe, U., Wawaer, I., Diehl, B., Eds.; Elsevier: Amsterdam, 2008; pp 407-427.
28. Lindon, J. C.; Nicholson, J. K.; Wilson, I. D. Prog. Nucl. Magn. Reson. Spectrosc. 1996, 29, 1-49.
29. Albert, K. J. Chromatogr., A 1995, 703, 123-147.
30. Lindon, J. C.; Nicholson, J. K.; Wilson, I. D. In On-line LC-NMR and Related Techniques; Albert, K., Ed.; John Wiley and Sons Ltd.: West Sussex, 2002; pp 45-87.
31. Olson, D. L.; Norcross, J. A.; O'Neil-Johnson, M.; Molitor, P. F.; Detlefsen, D. J.; Wilson, A. G.; Peck, T. L. Anal. Chem. 2004, 76, 2966-2974.
32. Keifer, P. A. In Modern Magnetic Resonance; Webb, G. A., Ed.; Springer: Netherlands, 2006; pp 1213-1219.
33. Spraul, M. In Modern Magnetic Resonance; Webb, G. A., Ed.; Springer: Netherlands, 2006; pp 1221-1228.
34. Zhang, Z.; Li, B.; Suwan, J.; Zhang, F.; Wang, Z.; Liu, H.; Mulloy, B.; Linhardt, R. J. J. Pharm. Sci. 2009, 98, 4017-4026.
35. Bossennec, V.; Petitou, M.; Perly, B. Biochem. J. 1990, 267, 625-630.
36. Toida, T.; Toyoda, H.; Imanari, T. Anal. Sci. 1993, 9, 53-58.