Profiling of active thrombin in human blood by supramolecular complexes

Angewandte Chemie - International Edition

Volumn 50, Issue 27, 2011, Pages 6075-6078

  Müller, Jens ^a   Becher, Tobias ^a   Braunstein, Jennifer ^a   Berdel, Philipp ^b   Gravius, Sascha ^b   Rohrbach, Falk ^c   Oldenburg, Johannes ^a   Mayer, Günter ^c   Pötzsch, Bernd ^a  

^a UNIVERSITY OF BONN   (Germany)

^b Clinic for Orthopedic Surgery   (Germany)

^c Life and Medical Sciences Institute   (Germany)

Author keywords

aptamers; coagulation; diagnostics; supramolecular chemistry; thrombin

Indexed keywords

ACTIVITY LEVELS; APTAMERS; CLINICAL CONDITIONS; COAGULATION SYSTEM; HUMAN BLOODS; IN-VIVO; KEY ENZYMES; SUPRAMOLECULAR COMPLEXES; THROMBIN;

COAGULATION; OLIGONUCLEOTIDES;

SUPRAMOLECULAR CHEMISTRY;

7 AMINO 4 METHYLCOUMARIN; 7-AMINO-4-METHYLCOUMARIN; APTAMER; ARGATROBAN; COUMARIN DERIVATIVE; DIAGNOSTIC AGENT; PEPTIDE; PIPECOLIC ACID DERIVATIVE; THROMBIN;

ARTICLE; BINDING SITE; BLOOD CLOTTING; CHEMISTRY; DRUG ANTAGONISM; ENZYME ASSAY; HUMAN; LIMIT OF DETECTION; METHODOLOGY; SENSITIVITY AND SPECIFICITY;

APTAMERS, NUCLEOTIDE; BINDING SITES; BLOOD COAGULATION; COUMARINS; ENZYME ASSAYS; HUMANS; LIMIT OF DETECTION; PEPTIDES; PIPECOLIC ACIDS; SENSITIVITY AND SPECIFICITY; THROMBIN;

EID: 79959524856     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201007032     Document Type: Article

References (19)

1. K. G. Mann, S. Butenas, K. E. Brummel, Arterioscler. Thromb. Vasc. Biol. 2003, 23, 17-25.
2. P. M. Mannucci, M. Levi, N. Engl. J. Med. 2007, 356, 2301-2311.
3. C. A. Salazar, G. Malaga, G. Malasquez, Cochrane Database Syst. Rev. 2010, 14, 4:CD005981.
4. S. Tombelli, M. Mascini, Curr. Opin. Mol. Ther. 2009, 11, 179-188
5. E. J. Cho, J. W. Lee, A. D. Ellington, Annu. Rev. Anal. Chem. 2009, 2, 241-264
6. T. M. Gronewold, S. Glass, E. Quandt, M. Famulok, Biosens. Bioelectron. 2005, 20, 2044-2052
7. M. Mir, M. Vreeke, I. Katakis, Electrochem. Commun. 2006, 8, 505-511
8. S. Centi, G. Messina, S. Tombelli, I. Palchetti, M. Mascini, Biosens. Bioelectron. 2008, 23, 1602-1609.
9. Y. Wang, B. Liu, Langmuir 2009, 25, 12787-12793
10. W. Zhao, M. M. Ali, M. A. Brook, Y. Li, Angew. Chem. 2008, 120, 6428-6436
11. Angew. Chem. Int. Ed. 2008, 47, 6330-6337
12. A. Pinto, M. C. Bermudo-Redondo, V. C. Ozalp, C. K. O'Sullivan, Mol. Biosyst. 2009, 5, 548-553
13. G. S. Baird, Am. J. Clin. Pathol. 2010, 134, 529-531.
14. J. Müller, B. Wulffen, B. Pötzsch, G. Mayer, ChemBioChem 2007, 8, 2223-2236
15. J. Müller, D. Freitag, G. Mayer, B. Pötzsch, J. Thromb. Haemostasis J. Thromb. Haemost. 2008, 6, 2105-2112.
16. A. Gruber, J. H. Griffin, Blood 1992, 79, 2340-2348
17. P. C. Y. Liaw, C. Ferrell, C. T. Esmon, J. Thromb. Haemostasis 2003, 1, 662-670.
18. T. E. Warkentin, A. Greinacher, S. Craven, L. Dewar, J. A. Sheppard, F. A. Ofosu, Thromb. Haemostasis 2005, 94, 958-964.
19. K. A. Bauer, Arch. Pathol. Lab. Med. 1993, 117, 71-77.