Correlation and Dissociation of Electrophysiology and Histopathology in the Assessment of Toxic Neuropathy

Toxicologic Pathology

Volumn 39, Issue 1, 2011, Pages 46-51

  Arezzo, Joseph C ^a   Litwak, Mona S ^a   Zotova, Elena G ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

biomarkers; electrophysiology; histopathology; neuropathology; neurotoxicity

Indexed keywords

BIOLOGICAL MARKER;

ANIMAL; ANIMAL MODEL; ELECTROPHYSIOLOGY; METHODOLOGY; MYELIN SHEATH; NERVE CONDUCTION; NERVE FIBER; PATHOLOGY; PERIPHERAL NERVE; PERIPHERAL NEUROPATHY; REVIEW; SPINAL CORD; TOXICITY AND INTOXICATION;

ANIMALS; AXONS; BIOLOGICAL MARKERS; ELECTROPHYSIOLOGICAL PHENOMENA; ELECTROPHYSIOLOGY; MODELS, ANIMAL; MYELIN SHEATH; NEURAL CONDUCTION; NEUROTOXICITY SYNDROMES; PERIPHERAL NERVES; PERIPHERAL NERVOUS SYSTEM DISEASES; SPINAL CORD;

EID: 79959505535     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623310390231     Document Type: Review

References (26)

1. Anderson T. D. Davidovich A. Arceo R. Brosnan C. Arezzo J. Schaumburg H. (1992). Peripheral neuropathy induced by 2’, 3’-dideoxycytidine. A rabbit model of 2’, 3’-dideoxycytidine neurotoxicity. Lab Invest 66, 63–74.
2. Arezzo J. C. (2009). What unique properties differentiate the various botulinum toxin products? Toxicon 54, 690–96.
3. Arezzo J. C. Schaumburg H. H. Spencer P. S. (1985). Structure and function of the somatosensory system; a neurotoxicological perspective. In Toxicology of the Eye, Ear, and Other Special Senses (Wallace Hayes A. ed.), pp. 41–54. Raven Press, New York, NY.
4. Arezzo J. C. Zotova E. (2002). Electrophysiologic measures of diabetic neuropathy: Mechanism and meaning. In Neurobiology of Diabetic Neuropathy. International Review of Neurobiology (Tomlinson D. ed.), Vol. 50. Academic Press, Elsevier Science, New York, NY.
5. Arif I. A. Khan H. A. (2010). Environmental toxins and Parkinson’s disease: Putative roles of impaired electron transport chain and oxidative stress. Toxicol Ind Health 26, 121–28.
6. Atherton D. D. Facer P. Roberts K. M. Misra V. P. Chizh B. A. Bountra C. Anand P. (2007). Use of the novel contact heat evoked potential stimulator (CHEPS) for the assessment of small fiber neuropathy: Correlation with skin flare responses and intra-epidermal nerve fibre counts. BMC Neurol 3, 21–30.
7. Cartwright M. E. Petruska J. Arezzo J. Doyle F. Litwak M. Morrissey R. E. MacDonald J. Davis T. E. (2009). Phospholipidosis in neurons caused by posaconazole, without evidence for functional neurologic effects. Toxicol Pathol 37, 902–10.
8. de la Monte S. M. Neusner A. Chu J. Lawton M. (2009). Epidemiological trends strongly suggest exposure as etiologic agents in the pathogenesis of sporadic Alzheimer’s disease, diabetes mellitus, and non-alcoholic steatohepatitis. J Alzheimer’s Dis 17, 519–29.
9. Dolly J. O. Black J. Williams R. S. Melling J. (1984). Acceptors for botulinum neurotoxin reside on motor nerve terminals and mediate its internalization. Nature 307, 457–60.
10. Genuis S. J. (2008). Toxic causes of mental illnesses are overlooked. Neurotoxicol 29, 1147–49.
11. Lee D.-K. Jacobs D. R. Jr. Steffes M. (2008). Association of organochlorine pesticides with peripheral neuropathy in patients with diabetes or impaired fasting glucose. Diabetes 57, 3108–11.
12. Niedermeyer E. (2005). Epileptic seizure disorders. In Electroencephalography: Basic Principles, Clinical Application, and Related Fields (Niedermeyer E. Da Silva F. L. eds.), 5th Edition, pp. 505–638. Lippincott Williams & Wilkins, New York, NY.
13. Park S. B. Krishnan A. V. Lin C. S. Goldstein D. Friedlander M. Kiernan M. C. (2008). Mechanisms underlying chemotherapy-induced neurotoxicity and the potential for neuroprotective strategies. Curr Med Chem 15, 3081–94.
14. Pazzaglia C. Valeriani M. (2009). Brain-evoked potentials as a tool for diagnosing neuropathic pain. Expert Rev Neurother 9, 759–71.
15. Polydefkis M. Hauer P. Sheth S. Sirdofsky M. Griffin J. W. McArthur J. C. (2004). The time course of epidermal nerve fiber regeneration: Studies in normal controls and in people with diabetes, with and without neuropathy. Brain 127, 1606–15.
16. Reasor M. J. Kacew S. (2001). Drug-induced phospholipidosis: Are there functional consequences? Exp Biol Med 226, 825–30.
17. Sanders T. Liu Y. Buchner V. Tchounwou P. B. (2009). Neurotoxic effects and biomarkers of lead exposure: A review. Rev Environ Health 24, 15–45.
18. Schaumburg H. H. Zotova E. Raine C. S. Tar M. Arezzo J. (2010). The rat caudal nerves: A model for experimental neuropathies. J Periph Nerv Syst 15, 128–39.
19. Schroeder C. E. Gibson J. B. Yarrington J. Heydorn W. E. Sussman N. M. Arezzo J. C. (1992). Effects of high dose gamma-vinyl GABA (vigabatrin) administration on visual and somatosensory evoked potentials in dogs. Epilepsia 33, S13–S25.
20. Spencer P. S. Schaumburg H. H. Ludolph A. C. (2000). Experimental and Clinical Neurotoxicology. Oxford University Press, New York, NY.
21. Stebbins G. T. Murphy C. M. (2009). Diffusion tensor imaging in Alzheimer’s disease and mild cognitive impairment. Behav Neurol 21, 39–49.
22. Swain S. M. Arezzo J. C. (2008). Neuropathy associated with microtubule inhibitors: diagnosis, incidence, and management. Clin Adv Hematol Oncol 6, 455–67.
23. van Valen E. Wekking E. van der Laan G. Sprangers M. van Dijk F. (2009). The course of chronic solvent induced encephalopathy: A systematic review. Neurotoxicol 30, 1172–86.
24. Waxman S. G. Ritchie J. M. (1985). Organization of ion channels in the myelinated nerve fiber. Science 228, 1502–7.
25. Wong D. F. Rosenberg P. B. Zhou Y. Kumar A. Raymont V. Ravert H. T. Dannals R. F. Nandi A. Brašć J. R. Weiguo Y. Hilton J. Lyketsos C. Kung H. F. Joshi A. D. Skovronsky D. M. Pontecorvo M. J. (2010). In vivo imaging of amyloid deposition in Alzheimer’s disease using the radioligand 18F-AV-45 (Flobetapir F 18). J Nucl Med 51, 913–20.
26. Zotova E. G. Schaumburg H. H. Raine C. S. Cannella B. Tar M. Melman A. Arezzo J. C. (2008). Effects of hyperglycemia on rat cavernous nerve axons: A functional and ultrastructural study. Exp Neurol 213, 439–47.