-
1
-
-
0034817075
-
ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain
-
Amann, J. M., et al. 2001. ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain. Mol. Cell. Biol. 21:6470-6483.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6470-6483
-
-
Amann, J.M.1
-
2
-
-
0030752361
-
E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas
-
Bain, G., et al. 1997. E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas. Mol. Cell. Biol. 17:4782-4791.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 4782-4791
-
-
Bain, G.1
-
3
-
-
0027992622
-
E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements
-
Bain, G., et al. 1994. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements. Cell 79:885-892.
-
(1994)
Cell
, vol.79
, pp. 885-892
-
-
Bain, G.1
-
4
-
-
0033405692
-
Thymocyte maturation is regulated by the activity of the helix-loop-helix protein
-
Bain, G., M. W. Quong, R. S. Soloff, S. M. Hedrick, and C. Murre. 1999. Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47. J. Exp. Med. 190:1605-1616.
-
(1999)
E47. J. Exp. Med.
, vol.190
, pp. 1605-1616
-
-
Bain, G.1
Quong, M.W.2
Soloff, R.S.3
Hedrick, S.M.4
Murre, C.5
-
5
-
-
0033568023
-
A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during alpha beta thymopoiesis
-
Barndt, R., M. F. Dai, and Y. Zhuang. 1999. A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during alpha beta thymopoiesis. J. Immunol. 163:3331-3343.
-
(1999)
J. Immunol.
, vol.163
, pp. 3331-3343
-
-
Barndt, R.1
Dai, M.F.2
Zhuang, Y.3
-
6
-
-
0025238437
-
The protein Id: a negative regulator of helix-loop-helix DNA binding proteins
-
Benezra, R., R. L. Davis, D. Lockshon, D. L. Turner, and H. Weintraub. 1990. The protein Id: a negative regulator of helix-loop-helix DNA binding proteins. Cell 61:49-59.
-
(1990)
Cell
, vol.61
, pp. 49-59
-
-
Benezra, R.1
Davis, R.L.2
Lockshon, D.3
Turner, D.L.4
Weintraub, H.5
-
7
-
-
40749153923
-
Differential roles for the E2A activation domains in B lymphocytes and macrophages
-
Bhalla, S., et al. 2008. Differential roles for the E2A activation domains in B lymphocytes and macrophages. J. Immunol. 180:1694-1703.
-
(2008)
J. Immunol.
, vol.180
, pp. 1694-1703
-
-
Bhalla, S.1
-
8
-
-
0034141972
-
CREB-binding protein and p300: molecular integrators of hematopoietic transcription
-
Blobel, G. A. 2000. CREB-binding protein and p300: molecular integrators of hematopoietic transcription. Blood 95:745-755.
-
(2000)
Blood
, vol.95
, pp. 745-755
-
-
Blobel, G.A.1
-
9
-
-
70350124893
-
Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors
-
Cai, Y., et al. 2009. Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors. Biochem. Biophys. Res. Commun. 390:295-301.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.390
, pp. 295-301
-
-
Cai, Y.1
-
10
-
-
53549119431
-
Deletion of Mtg16, a target of t(16;21), alters hematopoietic progenitor cell proliferation and lineage allocation
-
Chyla, B. J., et al. 2008. Deletion of Mtg16, a target of t(16;21), alters hematopoietic progenitor cell proliferation and lineage allocation. Mol. Cell. Biol. 28:6234-6247.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 6234-6247
-
-
Chyla, B.J.1
-
11
-
-
60849083235
-
Balance between Id and E proteins regulates myeloid-versus-lymphoid lineage decisions
-
Cochrane, S. W., Y. Zhao, R. S. Welner, and X. H. Sun. 2009. Balance between Id and E proteins regulates myeloid-versus-lymphoid lineage decisions. Blood 113:1016-1026.
-
(2009)
Blood
, vol.113
, pp. 1016-1026
-
-
Cochrane, S.W.1
Zhao, Y.2
Welner, R.S.3
Sun, X.H.4
-
12
-
-
77956942570
-
Structure of the AML1-ETO NHR3-PKA(RIIalpha) complex and its contribution to AML1-ETO activity
-
Corpora, T., et al. 2010. Structure of the AML1-ETO NHR3-PKA(RIIalpha) complex and its contribution to AML1-ETO activity. J. Mol. Biol. 402:560-577.
-
(2010)
J. Mol. Biol.
, vol.402
, pp. 560-577
-
-
Corpora, T.1
-
13
-
-
48749094942
-
E2A proteins promote development of lymphoid-primed multipotent progenitors
-
Dias, S., R. Mansson, S. Gurbuxani, M. Sigvardsson, and B. L. Kee. 2008. E2A proteins promote development of lymphoid-primed multipotent progenitors. Immunity 29:217-227.
-
(2008)
Immunity
, vol.29
, pp. 217-227
-
-
Dias, S.1
Mansson, R.2
Gurbuxani, S.3
Sigvardsson, M.4
Kee, B.L.5
-
14
-
-
77949375430
-
Myeloid translocation gene 16 (MTG16) interacts with Notch transcription complex components to integrate Notch signaling in hematopoietic cell fate specification
-
Engel, M. E., H. N. Nguyen, J. Mariotti, A. Hunt, and S. W. Hiebert. Myeloid translocation gene 16 (MTG16) interacts with Notch transcription complex components to integrate Notch signaling in hematopoietic cell fate specification. Mol. Cell. Biol. 30:1852-1863.
-
(2011)
Mol. Cell. Biol.
, vol.30
, pp. 1852-1863
-
-
Engel, M.E.1
Nguyen, H.N.2
Mariotti, J.3
Hunt, A.4
Hiebert, S.W.5
-
15
-
-
0026757174
-
Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt
-
Erickson, P., et al. 1992. Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt. Blood 80:1825-1831.
-
(1992)
Blood
, vol.80
, pp. 1825-1831
-
-
Erickson, P.1
-
16
-
-
0035959806
-
MTG8 proto-oncoprotein interacts with the regulatory subunit of type II cyclic AMP-dependent protein kinase in lymphocytes
-
Fukuyama, T., et al. 2001. MTG8 proto-oncoprotein interacts with the regulatory subunit of type II cyclic AMP-dependent protein kinase in lymphocytes. Oncogene 20:6225-6232.
-
(2001)
Oncogene
, vol.20
, pp. 6225-6232
-
-
Fukuyama, T.1
-
17
-
-
0032101547
-
The partner gene of AML1 in t(16;21) myeloid malignancies is a novel member of the MTG8(ETO) family
-
Gamou, T., et al. 1998. The partner gene of AML1 in t(16;21) myeloid malignancies is a novel member of the MTG8(ETO) family. Blood 91:4028-4037.
-
(1998)
Blood
, vol.91
, pp. 4028-4037
-
-
Gamou, T.1
-
18
-
-
0031723957
-
Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO
-
Gelmetti, V., et al. 1998. Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO. Mol. Cell. Biol. 18:7185-7191.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 7185-7191
-
-
Gelmetti, V.1
-
19
-
-
31444450865
-
ETO2 coordinates cellular proliferation and differentiation during erythropoiesis
-
Goardon, N., et al. 2006. ETO2 coordinates cellular proliferation and differentiation during erythropoiesis. EMBO J. 25:357-366.
-
(2006)
EMBO J
, vol.25
, pp. 357-366
-
-
Goardon, N.1
-
20
-
-
66349117082
-
Multivalent binding of the ETO corepressor to E proteins facilitates dual repression controls targeting chromatin and the basal transcription machinery
-
Guo, C., Q. Hu, C. Yan, and J. Zhang. 2009. Multivalent binding of the ETO corepressor to E proteins facilitates dual repression controls targeting chromatin and the basal transcription machinery. Mol. Cell. Biol. 29:2644-2657.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 2644-2657
-
-
Guo, C.1
Hu, Q.2
Yan, C.3
Zhang, J.4
-
21
-
-
33646671945
-
E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment
-
Ikawa, T., H. Kawamoto, A. W. Goldrath, and C. Murre. 2006. E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment. J. Exp. Med. 203:1329-1342.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1329-1342
-
-
Ikawa, T.1
Kawamoto, H.2
Goldrath, A.W.3
Murre, C.4
-
22
-
-
1642311876
-
Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent
-
Ikawa, T., H. Kawamoto, L. Y. Wright, and C. Murre. 2004. Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent. Immunity 20:349-360.
-
(2004)
Immunity
, vol.20
, pp. 349-360
-
-
Ikawa, T.1
Kawamoto, H.2
Wright, L.Y.3
Murre, C.4
-
23
-
-
0034664769
-
Combinatorial roles of the nuclear receptor corepressor in transcription and development
-
Jepsen, K., et al. 2000. Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell 102:753-763.
-
(2000)
Cell
, vol.102
, pp. 753-763
-
-
Jepsen, K.1
-
24
-
-
0037080629
-
IL-7Ralpha and E47: independent pathways required for development of multipotent lymphoid progenitors
-
Kee, B. L., G. Bain, and C. Murre. 2002. IL-7Ralpha and E47: independent pathways required for development of multipotent lymphoid progenitors. EMBO J. 21:103-113.
-
(2002)
EMBO J
, vol.21
, pp. 103-113
-
-
Kee, B.L.1
Bain, G.2
Murre, C.3
-
25
-
-
0031883569
-
The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family
-
Kitabayashi, I., et al. 1998. The AML1-MTG8 leukemic fusion protein forms a complex with a novel member of the MTG8(ETO/CDR) family, MTGR1. Mol. Cell. Biol. 18:846-858.
-
(1998)
MTGR1. Mol. Cell. Biol.
, vol.18
, pp. 846-858
-
-
Kitabayashi, I.1
-
26
-
-
50849125368
-
More complicated than it looks: assembly of Notch pathway transcription complexes
-
Kovall, R. A. 2008. More complicated than it looks: assembly of Notch pathway transcription complexes. Oncogene 27:5099-5109.
-
(2008)
Oncogene
, vol.27
, pp. 5099-5109
-
-
Kovall, R.A.1
-
27
-
-
33644641356
-
Determinants of lymphoidmyeloid lineage diversification
-
Laiosa, C. V., M. Stadtfeld, and T. Graf. 2006. Determinants of lymphoidmyeloid lineage diversification. Annu. Rev. Immunol. 24:705-738.
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 705-738
-
-
Laiosa, C.V.1
Stadtfeld, M.2
Graf, T.3
-
28
-
-
33645778328
-
The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity
-
Liu, Y., et al. 2006. The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity. Cancer Cell 9:249-260.
-
(2006)
Cancer Cell
, vol.9
, pp. 249-260
-
-
Liu, Y.1
-
29
-
-
50849112769
-
Delineating the cellular pathways of hematopoietic lineage commitment
-
Luc, S., N. Buza-Vidas, and S. E. Jacobsen. 2008. Delineating the cellular pathways of hematopoietic lineage commitment. Semin. Immunol. 20:213-220.
-
(2008)
Semin. Immunol.
, vol.20
, pp. 213-220
-
-
Luc, S.1
Buza-Vidas, N.2
Jacobsen, S.E.3
-
30
-
-
0031844689
-
The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein
-
Lutterbach, B., D. Sun, J. Schuetz, and S. W. Hiebert. 1998. The MYND motif is required for repression of basal transcription from the multidrug resistance 1 promoter by the t(8;21) fusion protein. Mol. Cell. Biol. 18:3604-3611.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3604-3611
-
-
Lutterbach, B.1
Sun, D.2
Schuetz, J.3
Hiebert, S.W.4
-
31
-
-
0031724804
-
ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors
-
Lutterbach, B., et al. 1998. ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors. Mol. Cell. Biol. 18:7176-7184.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 7176-7184
-
-
Lutterbach, B.1
-
32
-
-
34247092922
-
Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors
-
Mansson, R., et al. 2007. Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors. Immunity 26:407-419.
-
(2007)
Immunity
, vol.26
, pp. 407-419
-
-
Mansson, R.1
-
33
-
-
0027218725
-
The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript
-
Miyoshi, H., et al. 1993. The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript. EMBO J. 12: 2715-2721.
-
(1993)
EMBO J
, vol.12
, pp. 2715-2721
-
-
Miyoshi, H.1
-
34
-
-
38549129315
-
Myeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dependent transcription
-
Moore, A. C., et al. 2008. Myeloid translocation gene family members associate with T-cell factors (TCFs) and influence TCF-dependent transcription. Mol. Cell. Biol. 28:977-987.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 977-987
-
-
Moore, A.C.1
-
35
-
-
33745917083
-
The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain
-
Plevin, M. J., J. Zhang, C. Guo, R. G. Roeder, and M. Ikura. 2006. The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain. Proc. Natl. Acad. Sci. U. S. A. 103:10242-10247.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 10242-10247
-
-
Plevin, M.J.1
Zhang, J.2
Guo, C.3
Roeder, R.G.4
Ikura, M.5
-
36
-
-
0033136717
-
Deficient T cell fate specification in mice with an induced inactivation of Notch1
-
Radtke, F., et al. 1999. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 10:547-558.
-
(1999)
Immunity
, vol.10
, pp. 547-558
-
-
Radtke, F.1
-
37
-
-
35348868573
-
Epigenetic regulation of normal and malignant hematopoiesis
-
Rice, K. L., I. Hormaeche, and J. D. Licht. 2007. Epigenetic regulation of normal and malignant hematopoiesis. Oncogene 26:6697-6714.
-
(2007)
Oncogene
, vol.26
, pp. 6697-6714
-
-
Rice, K.L.1
Hormaeche, I.2
Licht, J.D.3
-
38
-
-
43249127082
-
ETO, but not leukemogenic fusion protein AML1/ETO, augments RBPJkappa/ SHARP-mediated repression of notch target genes
-
Salat, D., R. Liefke, J. Wiedenmann, T. Borggrefe, and F. Oswald. 2008. ETO, but not leukemogenic fusion protein AML1/ETO, augments RBPJkappa/ SHARP-mediated repression of notch target genes. Mol. Cell. Biol. 28:3502-3512.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 3502-3512
-
-
Salat, D.1
Liefke, R.2
Wiedenmann, J.3
Borggrefe, T.4
Oswald, F.5
-
39
-
-
0036916440
-
Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro
-
Schmitt, T. M., and J. C. Zuniga-Pflucker. 2002. Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity 17:749-756.
-
(2002)
Immunity
, vol.17
, pp. 749-756
-
-
Schmitt, T.M.1
Zuniga-Pflucker, J.C.2
-
40
-
-
77953643650
-
Synergy between IL-15 and Id2 promotes the expansion of human NK progenitor cells, which can be counteracted by the E protein HEB required to drive T cell development
-
Schotte, R., et al. 2010. Synergy between IL-15 and Id2 promotes the expansion of human NK progenitor cells, which can be counteracted by the E protein HEB required to drive T cell development. J. Immunol. 184:6670-6679.
-
(2010)
J. Immunol.
, vol.184
, pp. 6670-6679
-
-
Schotte, R.1
-
41
-
-
27944475459
-
ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis
-
Schuh, A. H., et al. 2005. ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis. Mol. Cell. Biol. 25:10235-10250.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 10235-10250
-
-
Schuh, A.H.1
-
42
-
-
33745591644
-
Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage development
-
Schwartz, R., I. Engel, M. Fallahi-Sichani, H. T. Petrie, and C. Murre. 2006. Gene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage development. Proc. Natl. Acad. Sci. U. S. A. 103:9976-9981.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 9976-9981
-
-
Schwartz, R.1
Engel, I.2
Fallahi-Sichani, M.3
Petrie, H.T.4
Murre, C.5
-
43
-
-
60549106831
-
E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors
-
Semerad, C. L., E. M. Mercer, M. A. Inlay, I. L. Weissman, and C. Murre. 2009. E2A proteins maintain the hematopoietic stem cell pool and promote the maturation of myelolymphoid and myeloerythroid progenitors. Proc. Natl. Acad. Sci. U. S. A. 106:1930-1935.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 1930-1935
-
-
Semerad, C.L.1
Mercer, E.M.2
Inlay, M.A.3
Weissman, I.L.4
Murre, C.5
-
44
-
-
0025939047
-
Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helixloop-helix proteins
-
Sun, X. H., N. G. Copeland, N. A. Jenkins, and D. Baltimore. 1991. Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helixloop-helix proteins. Mol. Cell. Biol. 11:5603-5611.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 5603-5611
-
-
Sun, X.H.1
Copeland, N.G.2
Jenkins, N.A.3
Baltimore, D.4
-
45
-
-
34447114547
-
A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription
-
Wei, Y., et al. 2007. A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcription. Nat. Struct. Mol. Biol. 14:653-661.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 653-661
-
-
Wei, Y.1
-
46
-
-
33746843079
-
A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis
-
Yan, M., et al. 2006. A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis. Nat. Med. 12:945-949.
-
(2006)
Nat. Med.
, vol.12
, pp. 945-949
-
-
Yan, M.1
-
47
-
-
79953694471
-
E47 regulates hematopoietic stem cell proliferation and energetics but not myeloid lineage restriction
-
Yang, Q., B. Esplin, and L. Borghesi. 2011. E47 regulates hematopoietic stem cell proliferation and energetics but not myeloid lineage restriction. Blood 117:3529-3538.
-
(2011)
Blood
, vol.117
, pp. 3529-3538
-
-
Yang, Q.1
Esplin, B.2
Borghesi, L.3
-
48
-
-
4344669438
-
E protein silencing by the leukemogenic AML1-ETO fusion protein
-
Zhang, J., M. Kalkum, S. Yamamura, B. T. Chait, and R. G. Roeder. 2004. E protein silencing by the leukemogenic AML1-ETO fusion protein. Science 305:1286-1289.
-
(2004)
Science
, vol.305
, pp. 1286-1289
-
-
Zhang, J.1
Kalkum, M.2
Yamamura, S.3
Chait, B.T.4
Roeder, R.G.5
|