Innovative reproductive technologies: Risks and responsibilities

Human Reproduction

Volumn 26, Issue 7, 2011, Pages 1604-1608

  Dondorp, W ^a   De Wert, G ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

assisted reproduction; innovation; IVF ICSI outcome, ethics; safety

Indexed keywords

CLINICAL PRACTICE; EMBRYO RESEARCH; EXPERIMENTAL MODEL; EXPERIMENTAL THERAPY; FERTILIZATION IN VITRO; FOLLOW UP; HUMAN; INFERTILITY THERAPY; MEDICAL RESEARCH; MEDICAL SOCIETY; NONHUMAN; REVIEW; SUBFERTILITY;

EID: 79959385423     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/der112     Document Type: Review

References (43)

1. Amor DJ, Halliday J. A review of known imprinting syndromes and their association with assisted reproduction technologies. Hum Reprod 2008;23:2826-2834.
2. Bavister BD. ARTs in action in nonhuman primates: symposium summary- advances and remaining issues. Reprod Biol Endocrinol 2004;2:43.
3. Biggers JD. Human Reproduction. Editorial Hum Reprod 2010;25:2156.
4. Biggers JD, Racowsky C. John D. Biggers: a conversation with Michael Summers & Catherine Racowsky, by Michael C. Summers and Catherine Racowsky. Hum Fertil (Camb) 2008;11:211-221.
5. Boggio A, Corbellini G. Regulating assisted reproduction in Italy: a 5-year assessment. Hum Fertil (Camb) 2009;12:81-88.
6. De Rycke M, Liebaers I, Van Steirteghem A. Epigenetic risks related to assisted reproductive technologies: risk analysis and epigenetic inheritance. Hum Reprod 2002;17:2487-2494. (Pubitemid 35174092)
7. Devolder K. Creating and sacrificing embryos for stem cells. J Med Ethics 2005;31:366-370. (Pubitemid 40823808)
8. De Wert GM, Mummery C. Human embryonic stem cells: research, ethics and policy. Hum Reprod 2003;18:672-682. (Pubitemid 36426942)
9. Dondorp WJ, De Wert GMWR. On waving the embryos banner. Embryonic stem cell research and moral reasoning in recent reports from the USA, the Netherlands and France. In: Gunning J, Holm S (eds). Ethics Law & Society, Vol. III. Ashgate, 2007;7-24.
10. Dondorp W, de Wert G, Pennings G, Shenfield F, Devroey P, Tarlatzis B, Barri P. ESHRE Task Force on Ethics and Law. Lifestyle-related factors and access to medically assisted reproduction. Hum Reprod 2010;25:578-583.
11. Eaton ML, Kennedy D. Innovation in Medical Technology. Ethical issues and Challenges. Baltimore: The John Hopkins University Press, 2007.
12. Franklin S, Roberts C. Born and Made. An Ethography of Preimplantation Genetic Diagnosis. Princeton and Oxford: Princeton University Press, 2006.
13. Geraedts JP, De Wert GM. Preimplantation genetic diagnosis. Clin Genet 2009;76:315-325.
14. Geraedts J, Collins J, Gianaroli L, Goossens V, Handyside A, Harper J, Montag M, Repping S, Schmutzler A. What next for preimplantation genetic screening?A polar body approach!. Hum Reprod 2010;25:575-577.
15. Grace KS, Sinclair KD. Assisted reproductive technology, epigenetics, and long-term health: a developmental time bomb still ticking. Semin Reprod Med 2009;27:409-416.
16. Halliday J. Outcomes of IVF conceptions: are they different? Best Pract Res Clin Obstet Gynaecol 2007;21:67-81.
17. Harper J, Coonen E, De Rycke M, Fiorentino F, Geraedts J, Goossens V, Harton G, Moutou C, Pehlivan Budak T, Renwick P et al. What next for preimplantation genetic screening (PGS)? A position statement from the ESHRE PGD Consortium Steering Committee. Hum Reprod 2010; 25:821-823.
18. Health Council of the Netherlands. IVF-related Research. The Hague: Health Council of the Netherlands, 1998, report nr 1998/8E. http://www. gezondheidsraad.nl/sites/default/files/98@08E.pdf (6 April 2011, date last accessed).
19. Hewitson L. Primate models for assisted reproductive technologies. Reproduction 2004;128:293-299. (Pubitemid 39242705)
20. Johnson MH, Franklin SB, Cottingham M, Hopwood N. Why the Medical Research Council refused Robert Edwards and Patrick Steptoe support for research on human conception in 1971. Hum Reprod 2010; 25:2157-2174.
21. Katari S, Turan N, Bibikova M, Erinle O, Chalian R, Foster M, Gaughan JP, Coutifaris C, Sapienza C. DNA methylation and gene expression differences in children conceived in vitro or in vivo. Hum Mol Genet 2009;18:3769-3778.
22. Lonergan P. State-of-the-art embryo technologies in cattle. Soc Reprod Fertil Suppl 2007;64:315-325.
23. Maher ER, Afnan M, Barratt CL. Epigenetic risks related to assisted reproductive technologies: epigenetics, imprinting, ART and icebergs? Hum Reprod 2003;18:2508-2511. (Pubitemid 37536613)
24. Margo CE. When is surgery research? Towards an operational definition of human research. J Med Ethics 2001;27:40-43. (Pubitemid 32149478)
25. Marques-Mari AI, Lacham-Kaplan O, Medrano JV, Pellicer A, Simón C. Differentiation of germ cells and gametes from stem cells. Hum Reprod Update 2009;15:379-390.
26. McDonald SD, Han Z, Mulla S, Murphy KE, Beyene J, Ohlsson A. Knowledge Synthesis Group. Preterm birth and low birth weight among in vitro fertilization singletons: a systematic review and meta-analyses. Eur J Obstet Gynecol Reprod Biol 2009;146:138-148.
27. McLaren A. IVF: regulation or prohibition? Nature 1989;342:469-470. (Pubitemid 20005804)
28. Mertes H, Pennings G. Gamete generation from stem cells. Will it ever be ethically acceptable? An ethicists view. In: Simon C, Pellicer A (eds). Stem Cells in Reproductive Medicine: Basic Science and Therapeutic Potential. London: Informa Healthcare, 2009, 14-21.
29. Niemitz EL, Feinberg AP. Epigenetics and assisted reproductive technology: a call for investigation. Am J Hum Genet 2004;74:599-609. (Pubitemid 38420091)
30. O'Neill O. A Question of Trust. The BBC Reith Lectures. Cambridge University Press, 2002.
31. Oktay K, Newton H, Aubard Y, Salha O, Gosden RG. Cryopreservation of immature human oocytes and ovarian tissue: an emerging technology? Fertil Steril 1998;69:1-7. (Pubitemid 28075612)
32. Owen CM, Segars JH Jr. Imprinting disorders and assisted reproductive technology. Semin Reprod Med 2009;27:417-428.
33. Pennings G, De Wert G, Shenfield F, Cohen J, Tarlatzis B, Devroey P. ESHRE Task Force on Ethics and Law 13: the welfare of the child in medically assisted reproduction. Hum Reprod 2007;22:2585-2588. (Pubitemid 47434200)
34. Reitsma AM, Moreno JD. Ethics of innovative surgery: US surgeons' definitions, knowledge, and attitudes. J Am Coll Surg 2005;200:103-110. (Pubitemid 41583121)
35. Sinclair KD. Assisted reproductive technologies and pregnancy outcomes: mechanistic insights from animal studies. Semin Reprod Med. 2008; 26:153-161. (Pubitemid 351342654)
36. Sinclair KD, Lea RG, Rees WD, Young LE. The developmental origins of health and disease: current theories and epigenetic mechanisms. Soc Reprod Fertil Suppl 2007;64:425-443.
37. Tachibana M, Sparman M, Sritanaudomchai H, Ma H, Clepper L, Woodward J, Li Y, Ramsey C, Kolotushkina O, Mitalipov S. Mitochondrial gene replacement in primate offspring and embryonic stem cells. Nature 2009;461:367-372.
38. Te Velde ER, Van Baar AL, Van Kooij RJ. Concerns about assisted reproduction. Lancet 1998;351:1524-1525. (Pubitemid 28230881)
39. The National Commission for the Protection of Human Subjects of Biomedical Behavioral Research. The Belmont Report. Ethical Principles and Guidelines for the Protection of Human Subjects of Research (1979). http://ohsr.od.nih.gov/guidelines/belmont.html (6 April 2011, date last accessed).
40. Ubaldi F, Anniballo R, Romano S, Baroni E, Albricci L, Colamaria S, Capalbo A, Sapienza F, Vajta G, Rienzi L. Cumulative ongoing pregnancy rate achieved with oocyte vitrification and cleavage stage transfer without embryo selection in a standard infertility program. Hum Reprod 2010;25:1199-1205. Epub 2010 Feb 25.
41. Wilkes M, Johns M. Informed consent and shared decision-making: a requirement to disclose to patients off-label prescriptions. PLoS Med 2008;5:e223.
42. World Medical Association. Declaration of Helsinki. Ethical Principles for Medical Research Involving Human Subjects (2008). http://www.wma. net/en/30publications/10policies/b3/(6 April 2011, date last accessed).
43. Young LE. Imprinting of genes and the Barker hypothesis. Twin Res 2001; 4:307-317. (Pubitemid 34151393)