Protective effects of salvianolate on microvascular flow in a porcine model of myocardial ischaemia and reperfusion

Archives of Cardiovascular Diseases

Volumn 104, Issue 5, 2011, Pages 313-324

  Han, Beibei ^a   Zhang, Xin ^b   Zhang, Qingyong ^a   Zhao, Gang ^a   Wei, Junbo ^a   Ma, Shixin ^a   Zhu, Wei ^a   Wei, Meng ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b BAOTOU MEDICAL COLLEGE   (China)

Author keywords

Apoptosis; injury; Ischaemia reperfusion; Microvascular flow; Oxidative stress; Salvianolate

Indexed keywords

DEOXYRIBONUCLEOTIDE; GLUTATHIONE; MALONALDEHYDE; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2; SALVIANOLATE; SUPEROXIDE DISMUTASE; THIOREDOXIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BALLOON OCCLUSION; CAPILLARY DENSITY; CONTRAST ECHOCARDIOGRAPHY; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DRUG MEGADOSE; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; HEART FUNCTION; HEART HEMODYNAMICS; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; INTRACORONARY INFUSION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; LOW DRUG DOSE; MEDICINAL PLANT; MICROVASCULARIZATION; NICK END LABELING; NO REFLOW PHENOMENON; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RADIX SALVIAE MILTIORRHIZAE; REPERFUSION; TRANSTHORACIC ECHOCARDIOGRAPHY; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARDIOVASCULAR AGENTS; CONTRAST MEDIA; CORONARY CIRCULATION; DISEASE MODELS, ANIMAL; GLUTATHIONE; HEMODYNAMICS; IN SITU NICK-END LABELING; INJECTIONS, INTRAVENOUS; MALONDIALDEHYDE; MICROCIRCULATION; MYOCARDIAL INFARCTION; MYOCARDIAL PERFUSION IMAGING; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; OXIDATIVE STRESS; PLANT EXTRACTS; PLANT ROOTS; PROTO-ONCOGENE PROTEINS C-BCL-2; SALVIA MILTIORRHIZA; SUPEROXIDE DISMUTASE; SWINE; THIOREDOXINS; TIME FACTORS; VENTRICULAR FUNCTION, LEFT;

EID: 79959380223     PISSN: 18752136     EISSN: 18752128     Source Type: Journal    
DOI: 10.1016/j.acvd.2011.02.004     Document Type: Article

References (27)

1. M. Ragosta, G. Camarano, and S. Kaul Microvascular integrity indicates myocellular viability in patients with recent myocardial infarction. New insights using myocardial contrast echocardiography Circulation 89 1994 2562 2569
2. H. Ito, A. Maruyama, and K. Iwakura Clinical implications of the 'no reflow' phenomenon. A predictor of complications and left ventricular remodeling in reperfused anterior wall myocardial infarction Circulation 93 1996 223 228 (Pubitemid 26031478)
3. S. Jin, G. Zhao, and Y. Fan Effect of salvianolic acid B on endothelin release and TXA2/PGI2 system in myocardial ischemia/reperfusion injury in rats Chin J Gerontol 24 2004 127 128
4. J.P. Xu, L.S. Sun, and H.Y. Wu Protective effect of salvianolic acid B on myocardial ischemia/reperfusion in rats Chin Pharm J 38 2003 595 597
5. X. Li, C. Yu, and W. Sun Simultaneous determination of magnesium lithospermate B, rosmarinic acid, and lithospermic acid in beagle dog serum by liquid chromatography/tandem mass spectrometry Rapid Commun Mass Spectrom 18 2004 2878 2882 (Pubitemid 39576830)
6. Xu YM, J. XL, Li T, et al. Methods for identification, purification, and manufacturing of the active constituents in Salvia miltiorrhiza (Dansheng) and the application of this product in enhancing cardiovascular functions. http://www.patentstorm.us/patents/6299910/description.html 2001; United States Patent 6299910.
7. P. Yan, X. Luo, and H. Shi Effect of depside salt from salvia miltiorrhiza on angina pectoris and platelet function Jie Ru Fang She Xue Za Zhi 12 Suppl. 2 2004 55 59
8. K. Wei, A.R. Jayaweera, and S. Firoozan Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion Circulation 97 1998 473 483 (Pubitemid 28090220)
9. J.J. Pacella, and F.S. Villanueva Effect of coronary stenosis on adjacent bed flow reserve: assessment of microvascular mechanisms using myocardial contrast echocardiography Circulation 114 2006 1940 1947 (Pubitemid 44665388)
10. P. Kowallik, R. Schulz, and B.D. Guth Measurement of regional myocardial blood flow with multiple colored microspheres Circulation 83 1991 974 982
11. U. Hoffmann, R. Millea, and C. Enzweiler Acute myocardial infarction: contrast-enhanced multi-detector row CT in a porcine model Radiology 231 2004 697 701 (Pubitemid 38668085)
12. H. Hasegawa, H. Takano, and K. Iwanaga Cardioprotective effects of granulocyte colony-stimulating factor in swine with chronic myocardial ischemia J Am Coll Cardiol 47 2006 842 849 (Pubitemid 43243110)
13. A. Holmgren, and M. Bjornstedt Thioredoxin and thioredoxin reductase Methods Enzymol 252 1995 199 208
14. S. Yegorova, A. Liu, and M.F. Lou Human lens thioredoxin: molecular cloning and functional characterization Invest Ophthalmol Vis Sci 44 2003 3263 3271 (Pubitemid 36909757)
15. S.H. Rezkalla, and R.A. Kloner No-reflow phenomenon Circulation 105 2002 656 662 (Pubitemid 34123444)
16. X.C. Li, C. Yu, and W.K. Sun Pharmacokinetics of magnesium lithospermate B after intravenous administration in beagle dogs Acta Pharmacol Sin 25 2004 1402 1407 (Pubitemid 39496800)
17. Y.H. Chen, G.H. Du, and J.T. Zhang Salvianolic acid B protects brain against injuries caused by ischemia-reperfusion in rats Acta Pharmacol Sin 21 2000 463 466
18. G. Theilmeier, P. Verhamme, and S. Dymarkowski Hypercholesterolemia in minipigs impairs left ventricular response to stress: association with decreased coronary flow reserve and reduced capillary density Circulation 106 2002 1140 1146 (Pubitemid 34970857)
19. S. Vandervelde, M.J. van Amerongen, and R.A. Tio Increased inflammatory response and neovascularization in reperfused vs. non-reperfused murine myocardial infarction Cardiovasc Pathol 15 2006 83 90
20. S. Kaul, and H. Ito Microvasculature in acute myocardial ischemia: part II: evolving concepts in pathophysiology, diagnosis, and treatment Circulation 109 2004 310 315 (Pubitemid 38133895)
21. Z.Q. Zhao, D.A. Velez, and N.P. Wang Progressively developed myocardial apoptotic cell death during late phase of reperfusion Apoptosis 6 2001 279 290 (Pubitemid 32708522)
22. Z.Q. Zhao, and J. Vinten-Johansen Myocardial apoptosis and ischemic preconditioning Cardiovasc Res 55 2002 438 455 (Pubitemid 34874939)
23. C.J. World, H. Yamawaki, and B.C. Berk Thioredoxin in the cardiovascular system J Mol Med 84 2006 997 1003
24. Y. Liu, and W. Min Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner Circ Res 90 2002 1259 1266 (Pubitemid 34787407)
25. S.H. Kim, M. Choi, and Y. Lee Natural therapeutic magnesium lithospermate B potently protects the endothelium from hyperglycaemia-induced dysfunction Cardiovasc Res 87 2010 713 722
26. X. Liu, R. Chen, and Y. Shang Superoxide radicals scavenging and xanthine oxidase inhibitory activity of magnesium lithospermate B from Salvia miltiorrhiza J Enzyme Inhib Med Chem 24 2009 663 668
27. M.W. Wang, D.F. Zhang, and J.J. Tang Effects of salvianolate on cardiomyocytic apoptosis and heart function in a swine model of acute myocardial infarction Zhong Xi Yi Jie He Xue Bao 7 2009 140 144