Radiosensitization of human cervical cancer cells by inhibiting ribonucleotide reductase: Enhanced radiation response at low-dose rates

International Journal of Radiation Oncology Biology Physics

Volumn 80, Issue 4, 2011, Pages 1198-1204

  Kunos, Charles A ^a   Colussi, Valdir C ^a   Pink, John ^a   Radivoyevitch, Tomas ^a   Oleinick, Nancy L ^a  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

Cervical cancer; Radiosensitization; Ribonucleotide reductase; Triapine

Indexed keywords

ACTIVITY ASSAYS; CANCER CELLS; CELL CYCLE; CELL LINES; CELL-CYCLE ARREST; CERVICAL CANCER CELLS; CERVICAL CANCERS; CLONOGENIC SURVIVAL; DNA DAMAGES; HIGH DOSE RATE; IRIDIUM-192; LOW DOSE; LOW DOSE RATE; RADIATION DOSE RATE; RADIATION RESPONSE; RADIATION SENSITIVITY; RADIO-SENSITIZATION; RIBONUCLEOTIDE REDUCTASE; THIOSEMICARBAZONES; TRIAPINE;

CELL CULTURE; CELLS; DISEASES; DOSIMETRY; ENZYME ACTIVITY; FLOW CYTOMETRY; IONIZING RADIATION; IRIDIUM;

RADIOTHERAPY;

3 AMINOPICOLINALDEHYDE THIOSEMICARBAZONE; IRIDIUM 192; RIBONUCLEOTIDE REDUCTASE;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER SURVIVAL; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELLULAR DISTRIBUTION; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA REPAIR; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IONIZING RADIATION; PRIORITY JOURNAL; RADIATION DOSE; RADIATION RESPONSE; RADIOSENSITIVITY; RADIOSENSITIZATION; UTERINE CERVIX CANCER;

CELL CYCLE; CELL LINE, TUMOR; ENZYME INHIBITORS; FEMALE; FLOW CYTOMETRY; G1 PHASE; HUMANS; IRIDIUM RADIOISOTOPES; NEOPLASM PROTEINS; PYRIDINES; RADIATION DOSAGE; RADIATION TOLERANCE; RADIOTHERAPY; RIBONUCLEOTIDE REDUCTASES; THIOSEMICARBAZONES; TUMOR STEM CELL ASSAY; UTERINE CERVICAL NEOPLASMS;

EID: 79959363029     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2011.01.034     Document Type: Article

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