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Volumn 5, Issue 3, 2011, Pages 131-135

Targeting small airways, a step further in asthma management

Author keywords

HFA BDP; Inhaled corticosteroids; Small airways; Ultrafine particles

Indexed keywords

BECLOMETASONE DIPROPIONATE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CHLOROFLUOROCARBON; NITRIC OXIDE;

EID: 79959351296     PISSN: 17526981     EISSN: 1752699X     Source Type: Journal    
DOI: 10.1111/j.1752-699X.2011.00240.x     Document Type: Review
Times cited : (13)

References (35)
  • 1
    • 36749016935 scopus 로고    scopus 로고
    • Time for a paradigm shift in asthma treatment: from relieving bronchospasm to controlling systemic inflammation
    • Bjermer L. Time for a paradigm shift in asthma treatment: from relieving bronchospasm to controlling systemic inflammation. J Allergy Clin Immunol 2007;120(6): 1269-75.
    • (2007) J Allergy Clin Immunol , vol.120 , Issue.6 , pp. 1269-1275
    • Bjermer, L.1
  • 2
    • 0034803992 scopus 로고    scopus 로고
    • History and future perspectives of treating asthma as a systemic and small airways disease
    • Bjermer L. History and future perspectives of treating asthma as a systemic and small airways disease. Respir Med 2001;95(9): 703-19.
    • (2001) Respir Med , vol.95 , Issue.9 , pp. 703-719
    • Bjermer, L.1
  • 3
    • 0031799195 scopus 로고    scopus 로고
    • The physiology of small airways
    • Macklem PT. The physiology of small airways. Am J Respir Crit Care Med 1998;157(5 Pt 2): S181-3.
    • (1998) Am J Respir Crit Care Med , vol.157 , Issue.5 PART 2
    • Macklem, P.T.1
  • 4
    • 10444279215 scopus 로고    scopus 로고
    • High-resolution CT findings in patients with near-fatal asthma: comparison of patients with mild-to-severe asthma and normal control subjects and changes in airway abnormalities following steroid treatment
    • Lee YM, Park JS, Hwang JH, etal. High-resolution CT findings in patients with near-fatal asthma: comparison of patients with mild-to-severe asthma and normal control subjects and changes in airway abnormalities following steroid treatment. Chest 2004;126(6): 1840-8.
    • (2004) Chest , vol.126 , Issue.6 , pp. 1840-1848
    • Lee, Y.M.1    Park, J.S.2    Hwang, J.H.3
  • 5
    • 52049123806 scopus 로고    scopus 로고
    • Complexity of chronic asthma and chronic obstructive pulmonary disease: implications for risk assessment, and disease progression and control
    • Frey U, Suki B. Complexity of chronic asthma and chronic obstructive pulmonary disease: implications for risk assessment, and disease progression and control. Lancet 2008;372(9643): 1088-99.
    • (2008) Lancet , vol.372 , Issue.9643 , pp. 1088-1099
    • Frey, U.1    Suki, B.2
  • 6
    • 79953711996 scopus 로고    scopus 로고
    • Assessment of small-airways disease using alveolar nitric oxide and impulse oscillometry in asthma and COPD
    • Williamson PA, Clearie K, Menzies D, Vaidyanathan S, Lipworth BJ. Assessment of small-airways disease using alveolar nitric oxide and impulse oscillometry in asthma and COPD. Lung 2010;189(2): 121-9.
    • (2010) Lung , vol.189 , Issue.2 , pp. 121-129
    • Williamson, P.A.1    Clearie, K.2    Menzies, D.3    Vaidyanathan, S.4    Lipworth, B.J.5
  • 7
    • 0028786415 scopus 로고
    • Peripheral airways responsiveness to cool, dry air in normal and asthmatic individuals
    • Kaminsky DA, Irvin CG, Gurka DA, etal. Peripheral airways responsiveness to cool, dry air in normal and asthmatic individuals. Am J Respir Crit Care Med 1995;152(6 Pt 1): 1784-90.
    • (1995) Am J Respir Crit Care Med , vol.152 , Issue.6 PART 1 , pp. 1784-1790
    • Kaminsky, D.A.1    Irvin, C.G.2    Gurka, D.A.3
  • 8
    • 0028958224 scopus 로고
    • Evaluation of airway inflammation by endobronchial and transbronchial biopsy in nocturnal and nonnocturnal asthma
    • Kraft M, Djukanovic R, Torvik J, etal. Evaluation of airway inflammation by endobronchial and transbronchial biopsy in nocturnal and nonnocturnal asthma. Chest 1995;107(Suppl. 3): 162S.
    • (1995) Chest , vol.107 , Issue.SUPPL. 3
    • Kraft, M.1    Djukanovic, R.2    Torvik, J.3
  • 9
    • 0034131479 scopus 로고    scopus 로고
    • Recurrent exacerbations in severe asthma are associated with enhanced airway closure during stable episodes
    • in 't Veen JC, Beekman AJ, Bel EH, Sterk PJ. Recurrent exacerbations in severe asthma are associated with enhanced airway closure during stable episodes. Am J Respir Crit Care Med 2000;161(6): 1902-6.
    • (2000) Am J Respir Crit Care Med , vol.161 , Issue.6 , pp. 1902-1906
    • in 't Veen, J.C.1    Beekman, A.J.2    Bel, E.H.3    Sterk, P.J.4
  • 10
    • 35949002726 scopus 로고    scopus 로고
    • Severe exacerbations predict excess lung function decline in asthma
    • Bai TR, Vonk JM, Postma DS, Boezen HM. Severe exacerbations predict excess lung function decline in asthma. Eur Respir J 2007;30(3): 452-6.
    • (2007) Eur Respir J , vol.30 , Issue.3 , pp. 452-456
    • Bai, T.R.1    Vonk, J.M.2    Postma, D.S.3    Boezen, H.M.4
  • 11
    • 77951128490 scopus 로고    scopus 로고
    • Pathological airway remodelling in inflammation
    • Westergren-Thorsson G, Larsen K, Nihlberg K, etal. Pathological airway remodelling in inflammation. Clin Respir J 2010;4(Suppl. 1): 1-8.
    • (2010) Clin Respir J , vol.4 , Issue.SUPPL. 1 , pp. 1-8
    • Westergren-Thorsson, G.1    Larsen, K.2    Nihlberg, K.3
  • 13
    • 0036799217 scopus 로고    scopus 로고
    • Increased alveolar nitric oxide concentration in asthmatic patients with nocturnal symptoms
    • Lehtimäki L, Kankaanranta H, Saarelainen S, Turjanmaa V, Moilanen E. Increased alveolar nitric oxide concentration in asthmatic patients with nocturnal symptoms. Eur Respir J 2002;20(4): 841-5.
    • (2002) Eur Respir J , vol.20 , Issue.4 , pp. 841-845
    • Lehtimäki, L.1    Kankaanranta, H.2    Saarelainen, S.3    Turjanmaa, V.4    Moilanen, E.5
  • 15
    • 78650283032 scopus 로고    scopus 로고
    • Comparison of central and peripheral airway involvement before and during methacholine, mannitol and eucapnic hyperventilation challenges in mild asthmatics
    • Aronsson D, Tufvesson E, Bjermer L. Comparison of central and peripheral airway involvement before and during methacholine, mannitol and eucapnic hyperventilation challenges in mild asthmatics. Clin Respir J 2011;5(1): 10-18.
    • (2011) Clin Respir J , vol.5 , Issue.1 , pp. 10-18
    • Aronsson, D.1    Tufvesson, E.2    Bjermer, L.3
  • 16
    • 39049122056 scopus 로고    scopus 로고
    • Allergic rhinitis with hyper-responsiveness differ from asthma in degree of peripheral obstruction during metacholine challenge test
    • Aronsson D, Tufvesson E, Ankerst J, Bjermer L. Allergic rhinitis with hyper-responsiveness differ from asthma in degree of peripheral obstruction during metacholine challenge test. Clin Physiol Funct Imaging 2008;28(2): 81-5.
    • (2008) Clin Physiol Funct Imaging , vol.28 , Issue.2 , pp. 81-85
    • Aronsson, D.1    Tufvesson, E.2    Ankerst, J.3    Bjermer, L.4
  • 17
    • 34748839579 scopus 로고    scopus 로고
    • Peripheral nitric oxide is increased in rhinitic patients with asthma compared to bronchial hyperresponsiveness
    • Tufvesson E, Aronsson D, Ankerst J, George SC, Bjermer L. Peripheral nitric oxide is increased in rhinitic patients with asthma compared to bronchial hyperresponsiveness. Respir Med 2007;101(11): 2321-6.
    • (2007) Respir Med , vol.101 , Issue.11 , pp. 2321-2326
    • Tufvesson, E.1    Aronsson, D.2    Ankerst, J.3    George, S.C.4    Bjermer, L.5
  • 19
    • 79953327120 scopus 로고    scopus 로고
    • IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways
    • Kearley J, Erjefalt JS, Andersson C, etal. IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways. Am J Respir Crit Care Med 2011;183(7): 865-75.
    • (2011) Am J Respir Crit Care Med , vol.183 , Issue.7 , pp. 865-875
    • Kearley, J.1    Erjefalt, J.S.2    Andersson, C.3
  • 20
    • 4844221717 scopus 로고    scopus 로고
    • A comparison of the effects of oral montelukast and inhaled salmeterol on response to rescue bronchodilation after challenge
    • Storms W, Chervinsky P, Ghannam AF, Bird S, Hustad CM, Edelman JM. A comparison of the effects of oral montelukast and inhaled salmeterol on response to rescue bronchodilation after challenge. Respir Med 2004;98(11): 1051-62.
    • (2004) Respir Med , vol.98 , Issue.11 , pp. 1051-1062
    • Storms, W.1    Chervinsky, P.2    Ghannam, A.F.3    Bird, S.4    Hustad, C.M.5    Edelman, J.M.6
  • 21
    • 0142074290 scopus 로고    scopus 로고
    • Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: one year, double blind, randomised, comparative trial
    • Bjermer L, Bisgaard H, Bousquet J, etal. Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: one year, double blind, randomised, comparative trial. BMJ 2003;327(7420): 891.
    • (2003) BMJ , vol.327 , Issue.7420 , pp. 891
    • Bjermer, L.1    Bisgaard, H.2    Bousquet, J.3
  • 22
    • 33646936053 scopus 로고    scopus 로고
    • Montelukast improves pulmonary function measured by impulse oscillometry in children with asthma (Mio study)
    • Nieto A, Pamies R, Oliver F, Medina A, Caballero L, Mazon A. Montelukast improves pulmonary function measured by impulse oscillometry in children with asthma (Mio study). Respir Med 2006;100(7): 1180-5.
    • (2006) Respir Med , vol.100 , Issue.7 , pp. 1180-1185
    • Nieto, A.1    Pamies, R.2    Oliver, F.3    Medina, A.4    Caballero, L.5    Mazon, A.6
  • 23
    • 20444506757 scopus 로고    scopus 로고
    • Alveolar nitric oxide in adults with asthma: evidence of distal lung inflammation in refractory asthma
    • Berry M, Hargadon B, Morgan A, etal. Alveolar nitric oxide in adults with asthma: evidence of distal lung inflammation in refractory asthma. Eur Respir J 2005;25(6): 986-91.
    • (2005) Eur Respir J , vol.25 , Issue.6 , pp. 986-991
    • Berry, M.1    Hargadon, B.2    Morgan, A.3
  • 24
    • 0030841890 scopus 로고    scopus 로고
    • Distribution of inhaled fluticasone propionate between human lung tissue and serum in vivo
    • Esmailpour N, Högger P, Rabe KF, Heitmann U, Nakashima M, Rohdewald P. Distribution of inhaled fluticasone propionate between human lung tissue and serum in vivo. Eur Respir J 1997;10(7): 1496-9.
    • (1997) Eur Respir J , vol.10 , Issue.7 , pp. 1496-1499
    • Esmailpour, N.1    Högger, P.2    Rabe, K.F.3    Heitmann, U.4    Nakashima, M.5    Rohdewald, P.6
  • 25
    • 79959366396 scopus 로고    scopus 로고
    • Targeting small airways in asthma: improvement in clinical benefit?
    • doi:10.1111/j.1752-699X.2010.00235.x.
    • Ulrik CS, Lange P. Targeting small airways in asthma: improvement in clinical benefit? Clin Resp J 2011; doi:10.1111/j.1752-699X.2010.00235.x.
    • (2011) Clin Resp J
    • Ulrik, C.S.1    Lange, P.2
  • 26
    • 0033372831 scopus 로고    scopus 로고
    • The distal airways: are they important in asthma?
    • Kraft M. The distal airways: are they important in asthma? Eur Respir J 1999;14(6): 1403-17.
    • (1999) Eur Respir J , vol.14 , Issue.6 , pp. 1403-1417
    • Kraft, M.1
  • 28
    • 0034825819 scopus 로고    scopus 로고
    • Dose-response for adrenal suppression with hydrofluoroalkane formulations of fluticasone propionate and beclomethasone dipropionate
    • Fowler SJ, Orr LC, Wilson AM, Sims EJ, Lipworth BJ. Dose-response for adrenal suppression with hydrofluoroalkane formulations of fluticasone propionate and beclomethasone dipropionate. Br J Clin Pharmacol 2001;52(1): 93-5.
    • (2001) Br J Clin Pharmacol , vol.52 , Issue.1 , pp. 93-95
    • Fowler, S.J.1    Orr, L.C.2    Wilson, A.M.3    Sims, E.J.4    Lipworth, B.J.5
  • 29
    • 0031817795 scopus 로고    scopus 로고
    • Inflammatory cell distribution within and along asthmatic airways
    • Haley KJ, Sunday ME, Wiggs BR, etal. Inflammatory cell distribution within and along asthmatic airways. Am J Respir Crit Care Med 1998;158(2): 565-72.
    • (1998) Am J Respir Crit Care Med , vol.158 , Issue.2 , pp. 565-572
    • Haley, K.J.1    Sunday, M.E.2    Wiggs, B.R.3
  • 30
    • 69249151708 scopus 로고    scopus 로고
    • Effects of ciclesonide and fluticasone on cortisol secretion in patients with persistent asthma
    • Derom E, Louis R, Tiesler C, Engelstätter R, Kaufman JM, Joos GF. Effects of ciclesonide and fluticasone on cortisol secretion in patients with persistent asthma. Eur Respir J 2009;33(6): 1277-86.
    • (2009) Eur Respir J , vol.33 , Issue.6 , pp. 1277-1286
    • Derom, E.1    Louis, R.2    Tiesler, C.3    Engelstätter, R.4    Kaufman, J.M.5    Joos, G.F.6
  • 31
    • 20444466142 scopus 로고    scopus 로고
    • Protein binding and its potential for eliciting minimal systemic side effects with a novel inhaled corticosteroid, ciclesonide
    • Rohatagi S, Luo Y, Shen L, etal. Protein binding and its potential for eliciting minimal systemic side effects with a novel inhaled corticosteroid, ciclesonide. Am J Ther 2005;12(3): 201-9.
    • (2005) Am J Ther , vol.12 , Issue.3 , pp. 201-209
    • Rohatagi, S.1    Luo, Y.2    Shen, L.3
  • 32
    • 0035131760 scopus 로고    scopus 로고
    • Cumulative and single-dose design to assess the bronchodilator effects of beta2-agonists in individuals with asthma
    • Fishwick D, Bradshaw L, Macdonald C, etal. Cumulative and single-dose design to assess the bronchodilator effects of beta2-agonists in individuals with asthma. Am J Respir Crit Care Med 2001;163(2): 474-7.
    • (2001) Am J Respir Crit Care Med , vol.163 , Issue.2 , pp. 474-477
    • Fishwick, D.1    Bradshaw, L.2    Macdonald, C.3
  • 33
    • 78649940445 scopus 로고    scopus 로고
    • A pilot study to assess lung deposition of HFA-beclomethasone and CFC-beclomethasone from a pressurized metered dose inhaler with and without add-on spacers and using varying breathhold times
    • Leach CL, Colice GL. A pilot study to assess lung deposition of HFA-beclomethasone and CFC-beclomethasone from a pressurized metered dose inhaler with and without add-on spacers and using varying breathhold times. J Aerosol Med Pulm Drug Deliv 2010;23(6): 355-61.
    • (2010) J Aerosol Med Pulm Drug Deliv , vol.23 , Issue.6 , pp. 355-361
    • Leach, C.L.1    Colice, G.L.2
  • 34
    • 0034065781 scopus 로고    scopus 로고
    • The role of dispersion in particle deposition in human airways
    • Sarangapani R, Wexler AS. The role of dispersion in particle deposition in human airways. Toxicol Sci 2000;54(1): 229-36.
    • (2000) Toxicol Sci , vol.54 , Issue.1 , pp. 229-236
    • Sarangapani, R.1    Wexler, A.S.2
  • 35
    • 78249266316 scopus 로고    scopus 로고
    • Regional deposition of particles in an image-based airway model: large-eddy simulation and left-right lung ventilation asymmetry
    • Lambert AR, O'Shaughnessy P, Tawhai MH, Hoffman EA, Lin CL. Regional deposition of particles in an image-based airway model: large-eddy simulation and left-right lung ventilation asymmetry. Aerosol Sci Technol 2011;45(1): 11-25.
    • (2011) Aerosol Sci Technol , vol.45 , Issue.1 , pp. 11-25
    • Lambert, A.R.1    O'Shaughnessy, P.2    Tawhai, M.H.3    Hoffman, E.A.4    Lin, C.L.5


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