Assessment of small-airways disease using alveolar nitric oxide and impulse oscillometry in asthma and COPD

Lung

Volumn 189, Issue 2, 2011, Pages 121-129

  Williamson, Peter A ^a   Clearie, Karine ^a   Menzies, Daniel ^a   Vaidyanathan, Sriram ^a   Lipworth, Brian J ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Airway markers; Asthma; COPD

Indexed keywords

ANTIHISTAMINIC AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MACROLIDE; NITRIC OXIDE; THEOPHYLLINE;

AIRWAY CONDUCTANCE; AIRWAY RESISTANCE; ARTICLE; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; IMPULSE OSCILLOMETRY; MAJOR CLINICAL STUDY; MALE; OSCILLOMETRY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RESPIRATORY FUNCTION; SMALL AIRWAY DISEASE; SPIROMETRY;

ADULT; AGED; ASTHMA; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; DISEASE PROGRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; NITRIC OXIDE; OSCILLOMETRY; PULMONARY ALVEOLI; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY FUNCTION TESTS; SEVERITY OF ILLNESS INDEX; SPIROMETRY;

EID: 79953711996     PISSN: 03412040     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00408-010-9275-y     Document Type: Article

References (34)

1. Vestbo J, Anderson W, Coxson HO, Crim C, Dawber F, Edwards L, Hagan G, Knobil K, Lomas DA, MacNee W, Silverman EK, Tal-Singer R (2008) Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE). Eur Respir J 31:869-873
2. Taylor DR (2009) Risk assessment in asthma and COPD: a potential role for biomarkers? Thorax 64:261-264
3. Brightling CE, Green RH, Pavord ID (2005) Biomarkers predicting response to corticosteroid therapy in asthma. Treat Respir Med 4:309-316 (Pubitemid 43127499)
4. Sont JK, Willems LNA, Bel EH, van Krieken HJM, Vandenbroucke JP, Sterk PJ (1999) Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment. Am J Respir Crit Care Med 159:1043-1051 (Pubitemid 29202534)
5. Green RH, Brightling CE, McKenna S, Hargadon B, Parker D, Bradding P, Wardlaw AJ, Pavord ID (2002) Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 360:15-21
6. American Thoracic Society (2000) Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions. American Thoracic Society. Am J Respir Crit Care Med 162:2341-2351
7. American Thoracic Society; European Respiratory Society (2005) ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am J Respir Crit Care Med 171:912-930
8. American Thoracic Society Workshop (2006) ATS Workshop Proceedings: Exhaled nitric oxide and nitric oxide oxidative metabolism in exhaled breath condensate: executive summary. Am J Respir Crit Care Med 173:811-813
9. Tsoukias NM, George SC (1998) A two-compartment model of pulmonary nitric oxide exchange dynamics. J Appl Physiol 85:653-666 (Pubitemid 28365835)
10. Tsoukias NM, Shin HW, Wilson AF, George SC (2001) A single-breath technique with variable flow rate to characterize nitric oxide exchange dynamics in the lungs. J Appl Physiol 91:477-487 (Pubitemid 32574759)
11. Berry M, Hargadon B, Morgan A, Shelley M, Richter J, Shaw D, Green RH, Brightling C, Wardlaw AJ, Pavord ID (2005) Alveolar nitric oxide in adults with asthma: evidence of distal lung inflammation in refractory asthma. Eur Respir J 25:986-991 (Pubitemid 40823772)
12. Cohen J, Douma WR, ten Hacken NH, Vonk JM, Oudkerk M, Postma DS (2008) Ciclesonide improves measures of small airway involvement in asthma. Eur Respir J 31(6):1213-1220
13. Williamson PA, Menzies D, Nair A, Tutuncu A, Lipworth BJ (2009) A proof-of-concept study to evaluate the antiinflammatory effects of a novel soluble cyclodextrin formulation of nebulized budesonide in patients with mild to moderate asthma. Ann Allergy Asthma Immunol 102:161-167
14. Condorelli P, Shin HW, George SC (2004) Characterizing airway and alveolar nitric oxide exchange during tidal breathing using a three-compartment model. J Appl Physiol 96:1832-1842 (Pubitemid 38580010)
15. Kerckx Y, Michils A, Van Muylem A (2008) Airway contribution to alveolar nitric oxide in healthy subjects and stable asthma patients. J Appl Physiol 104:918-924 (Pubitemid 351507926)
16. Condorelli P, Shin HW, Aledia AS, Silkoff PE, George SC (2007) A simple technique to characterize proximal and peripheral nitric oxide exchange using constant flow exhalations and an axial diffusion model. J Appl Physiol 102:417-425 (Pubitemid 46089793)
17. Dubois AB, Brody AW, Lewis DH, Burgess BF Jr (1956) Oscillation mechanics of lungs and chest in man. J Appl Physiol 8:587-594
18. Oostveen E, MacLeod D, Lorino H, Farre R, Hantos Z, Desager K, Marchal F (2003) The forced oscillation technique in clinical practice: methodology, recommendations and future developments. Eur Respir J 22:1026-1041 (Pubitemid 37540659)
19. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J (2005) Standardisation of spirometry. Eur Respir J 26:319-338 (Pubitemid 41079078)
20. Borrill ZL, Houghton CM, Woodcock AA, Vestbo J, Singh D (2005) Measuring bronchodilation in COPD clinical trials. Br J Clin Pharmacol 59:379-384 (Pubitemid 40523880)
21. Fardon TC, Burns P, Barnes ML, Lipworth BJ (2006) A comparison of 2 extrafine hydrofluoroalkane-134a-beclomethasone formulations on methacholine hyperresponsiveness. Ann Allergy Asthma Immunol 96:422-430
22. Shaw DE, Berry MA, Thomas M, Green RH, Brightling CE, Wardlaw AJ, Pavord ID (2007) The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial. Am J Respir Crit Care Med 176:231-237 (Pubitemid 47195872)
23. Gelb AF, Taylor CF, Nussbaum E, Gutierrez C, Schein A, Shinar CM, Schein MJ, Epstein JD, Zamel N (2004) Alveolar and airway sites of nitric oxide inflammation in treated asthma. Am J Respir Crit Care Med 170:737-741 (Pubitemid 39298987)
24. van Veen IH, Sterk PJ, Schot R, Gauw SA, Rabe KF, Bel EH (2006) Alveolar nitric oxide versus measures of peripheral airway dysfunction in severe asthma. Eur Respir J 27:951-956 (Pubitemid 44911108)
25. Berry MA, Shaw D, Morgan A, Hargadon B, McKenna S, Shelley M, Green RH, Brightling CE, Wardlaw AJ, Pavord ID (2004) Association between alveolar nitric oxide concentration and broncheoalveolar lavage but not bronchial wash eosinophil count in patients with asthma. Thorax 59:ii50
26. Brindicci C, Ito K, Barnes PJ, Kharitonov SA (2007) Differential flow analysis of exhaled nitric oxide in patients with asthma of differing severity. Chest 131:1353-1362 (Pubitemid 46762339)
27. Saari SM, Vidgren MT, Koskinen MO, Turjanmaa VM, Waldrep JC, Nieminen MM (1998) Regional lung deposition and clearance of 99mTc-labeled beclomethasone-DLPC liposomes in mild and severe asthma. Chest 113:1573-1579 (Pubitemid 28307162)
28. Brindicci C, Ito K, Resta O, Pride NB, Barnes PJ, Kharitonov SA (2005) Exhaled nitric oxide from lung periphery is increased in COPD. Eur Respir J 26:52-59 (Pubitemid 40945931)
29. Roy K, Borrill ZL, Starkey C, Hazel AL, Morris J, Vestbo J, Singh D (2007) Use of different exhaled nitric oxide multiple flow rate models in COPD. Eur Respir J 29:651-659 (Pubitemid 46554613)
30. Borrill ZL, Houghton CM, Tal-Singer R, Vessey SR, Faiferman I, Langley SJ, Singh D (2008) The use of plethysmography and oscillometry to compare long-acting bronchodilators in patients with COPD. Br J Clin Pharmacol 65:244-252 (Pubitemid 351171272)
31. Houghton CM, Woodcock AA, Singh D (2004) A comparison of lung function methods for assessing dose-response effects of salbutamol. Br J Clin Pharmacol 58:134-141 (Pubitemid 39043993)
32. Van Noord JA, Smeets J, Clement J, Van de Woestijne KP, Demedts M (1994) Assessment of reversibility of airflow obstruction. Am J Respir Crit Care Med 150:551-554 (Pubitemid 24252374)
33. Burns GP, Gibson GJ (2002) A novel hypothesis to explain the bronchconstrictor effect of deep inspiration in asthma. Thorax 57:116-119 (Pubitemid 34123883)
34. Kolsum U, Borrill Z, Roy K, Starkey C, Vestbo J, Houghton C, Singh D (2009) Impulse oscillometry in COPD: identification of measurements related to airway obstruction, airway conductance and lung volumes. Respir Med 103:136-143