Meloxicam carbopol-based gels: Characterization and evaluation

Current Drug Delivery

Volumn 8, Issue 4, 2011, Pages 407-415

  Sareen, Rashmi ^a   Kumar, Sandeep ^b   Gupta, G D ^b  

^a Abhilashi College of Pharmacy   (India)

^b Amar Shaheed Baba Ajit Singh Jujhar Singh PG Memorial College of Pharmacy   (India)

Author keywords

Bioadhesion; Meloxicam; Penetration enhancers; Topical gel

Indexed keywords

CARBOMER; CARBOPOL 934; CARBOPOL 940; MELOXICAM; OLEIC ACID; PENETRATION ENHANCING AGENT; POLYMER; POLYSORBATE 80; SESAME SEED OIL;

ADHESION; ARTICLE; BIOADHESION; CHEMICAL COMPOSITION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIFFUSION; DISPERSION; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG STABILITY; HYDROGEL; IN VITRO STUDY; KESHARY CHEIN DIFFUSION CELL; NONHUMAN; PH; PRIORITY JOURNAL; SKIN; SWINE; VISCOMETER; VISCOSITY;

ACRYLATES; ACRYLIC RESINS; ADMINISTRATION, CUTANEOUS; ANIMALS; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; GELS; HYDROGELS; HYDROGEN-ION CONCENTRATION; PERMEABILITY; PHARMACOKINETICS; SKIN; SKIN ABSORPTION; SWINE; THIAZINES; THIAZOLES; VISCOSITY;

EID: 79959326211     PISSN: 15672018     EISSN: 18755704     Source Type: Journal    
DOI: 10.2174/156720111795768013     Document Type: Article

References (41)

1. Kesavanarayanan, K.S.; Ilavarasan, R. Topical dosage form of valdecoxib: Preparation and pharmacological evaluation. Acta Pharm., 2007, 57, 199-9.
2. Gupta, G.D.; Gaud, R.S. Antiinflammatory activity of tenoxicam gel on carrageenan - induced paw oedema in rats. Indian J. Pharm. Sci., 2006, 356-59.
3. Suzuki, T. Preparation and evaluation of topical preparation of indomethacin. Indian J. Pharm. Sci., 1988, 32, 145-49.
4. Uma Devi, S.; Ganesan, M.; Mohanta, G.P. Design and evaluation of tetracycline hydrochloride gels. Indian Drugs, 2002, 39(10), 552-54.
5. Saleem, M.A.; Sanaullah, S.; Purohit, M.G. Antimicrobial and wound healing activity of prepared gatifloxacin topical gels. Indian Drugs, 2005, 43(4), 292-95.
6. Gohel, M.C.; Jani, G.K.; Amin, A.; Bajaj, S.; Dave, B.S. Application of simplex lattice design for the development of transdermal gels of diclofenac sodium. Indian J. Pharm. Sci., 2000, 62(2), 108-14.
7. Loganathan, V.; Jaswanth, A.; Sulaiman, A.; Rajaseskaran, A.; Manimaran, S.; Kumar, S.B. The effects of polymers and permeation enhancers on release of flurbiprofen from gel formulation. Indian J. Pharm. Sci., 2001, 200-204.
8. Goodrich, B.F. Product information on carbopol. Pharm. Res., 1995, 11, 1396-400.
9. Shin, S.C.; Kim, J.Y.; Oh, I.J. Mucoadhesive and physicochemical characterization of carbopol-poloxamer gels containing triamci-nolone acetonide. Drug Dev. Ind. Pharm., 2000, 26, 307-12.
10. Zhou, M.; Donovan, M.D. Intranasal mucociliary clearance of putative bioadhesive polymer gels. Int. J. Pharm., 1996, 135, 115-25.
11. Mehta, R. M. Pharmaceutics II, 2nd ed.; Vallabh Prakashan: New Delhi, 2000.
12. Moffat, A.C.; Osselton, M.D.; Widdop, B. Clarke's Analysis of Drugs and Poisons, Pharmaceutical Press: London, 2006.
13. Poonia, B.S.; Choudhury, P.K. Penetration enhancers for transder-mal drug delivery of systematic agents. J. Pharm. Res., 2007, 6(2), 44-50.
14. Tiwary, A.K.; Sapra, B.; Gupta, S. Techniques for studying the molecular basis of percutaneous permeation enhancement. Indian Drugs, 1999, 36(8), 492-98.
15. Dinda, S.C.; Ratna, V. Enhancement of skin permeation of ibupro-fen from ointments and gels by sesame oil, sunflower oil and oleic acid. Indian J. Pharm. Sci., 2006, 313-16.
16. Reddy, S.M.; Mutalik, S.; Rao, V.G. Preparation and evaluation of minoxidil gel for topical application in alopecia. Indian J. Pharm. Sci., 2006, 432-36.
17. Robinson, J.R.; Bologna, W.J. Vaginal and reproductive system treatments using a bioadhesive polymer. J. Control Release, 1994, 28, 87-94.
18. Diez-Sales, O.; Garrigues, T.M.; Herraez, J.V.; Belda, R.; Martin-Villodre, A.; Herraez, M. In-Vitro percutaneous penetration of acy-clovir from solvent systems and carbopol 971-P hydrgels: influence of propylene glycol. J. Pharm. Sci., 2005, 94, 1039-47.
19. Guruswami, S.; Kumar, V.; Mishra, D.N. Characterization and in vitro dissolution studies of solid systems of valdecoxib with chito-san. Chem. Pharm. Bull., 2006, 54, 1102-6.
20. Nappinnai, M.; Pakalapali, S.; Arimilli, R. Rofecoxib gels: Preparation and evaluation. Indian Drugs, 2006, 43(6), 513-15.
21. Loganathan, V.; Jaswanth, A.; Sulaiman, A.; Rajaseskaran, A.; Manimaran, S.; Kumar, S.B. The effects of polymers and permeation enhancers on release of flurbiprofen from gel formulation. Indian J. Pharm. Sci., 2001, 200-4.
22. Ritger, P.L.; Peppas, N.A. Modelling of water transport solute release in physiologically sensitive gels. J. Control. Release, 1987, 5, 37-46.
23. Mutimier, M.N.; Reffkin, C.; Hill, J.A.; Marry, E.; Glickman, M.E.; Cry, G.N. Modern ointment base technology II. J. Am. Pharm. Assoc. Sci., 1965, 45, 212-20.
24. Sahoo, S.K.; Samal, A.R.; Mallick, A.A.; Patra, S.; Senapati, P.C.; Barik, B.B. Estimation and evaluation of secnidazole gel. Ind. Pharmacist, 2006, 73-76.
25. Kim, J.Y.; Song, J.Y.; Lee, E.J.; Park, S.K. Rheological properties and microstructure of carbopol gel network sysem. Colloid Polym. Sci., 2003, 281, 614-23.
26. Shaikh, M.; Jadhav, S.L.; Jadhav, K.R.; Kadam, V.J.; Pisal, S.S. Aceclofenac Organogels: In Vitro and In Vivo Characterization. Curr. Drug Deliv., 2009, 6, 1-7.
27. Barbero, A.M.; Frasch, H.F. Pig and guinea pig skin as surrogates for human in vitro penetration studies: A quantitative review. Toxicology in Vitro, 2009, 23, 1-13.
28. Yuan, Y.; Li, S.; Mo, F.; Zhong, D. Investigation of microemulsion system for transdermal delivery of meloxiocam. Int. J. Pharm., 2006, 321, 117-23.
29. Kikwai, L.; Babu, J.; Prado, R.; Kolot, A.; Cheryl, A.; Armstong, A.; John, C.; Singh, M. In vitro and in vivo evaluation of topical formulations of spantide II. AAPS Pharm. Sci. Tech., 2005, 6(4), 65-72.
30. Panda, D.; SI, S.; Swain, S.; Kanungo, S.K.; Gupta, R. Preparation and evaluation of gels from gum of moringa oleifera. Indian J. Pharm. Sci., 2006, 777-79.
31. Guangwei, L.; Jun, H.W. Diffusion studies of methotrexate in carbopol and poloxamer gels. Int. J. Pharm., 1998, 160, 1-9
32. Chen, H.; Chang, X.; Du, D.; Li, J.; Xu, H.; Yang, X. Microemul-sion-based hydrogel formulation of ibuprofen for topical delivery. Int. J. Pharmaceutics., 2006, 315, 52-58.
33. Ali, M.; Horikawa, S.; Venkatesh, S.; Saha, J.; Hong, J.W.; Byrne, M.E. Zero order therapeutic release from imprinted hydrogel contact lenses within invitro physiological ocular tear flow. J. Control. Release, 2007, 124, 154-62.
34. Liberman, H.A.; Rieger, M.M.; Banker, G.S. Pharmaceutical Dosage Forms: Disperse Systems, Marcel Dekker: New York, 1989, 594-10.
35. Draize, J.H.; Woodward, G.; Calvery, O.H. Method for the study of Irritation and toxicity of substance applied topically to the skin and mucous membrane. J. Pharmacol. Exp. Ther., 1994, 82, 377-90.
36. Constantia, E.K.; Claudia, V.; Martina, L.; Andreas, B.S. Design and An in-vitro evalution of novel bioadhesive vaginal drug delivery systems for clotrimazole. J. Control. Release, 2002, 81, 347-54.
37. Alka, G.; Sanjay, G.; Roop, K.K. Measurement of Bioadhesive Strength of Mucoadhesive Buccal Tablets: Design of An In-Vitro Assembly. Indian Drug, 1992, 4(30), 152-55.
38. Carstensen, J.T. Drug Stability, Principles & Practices, Marcel Dekker: New York, 1989.
39. Sandile, M.K.; Roderick, B. Evaluation of rate of swelling and erosion of verapamil sustained release matrix tablets. Drug Dev. Ind. Pharm., 2006, 32, 1139-48.
40. Jain, N.K.; Misra, P.R. Program in Controlled and Novel Drug Delivery System, 1st ed.; CBS Publishers and Distributors: New Delhi, 2004.
41. Siepmann, J.; Siepmann, F. Mathematical modeling of drug delivery. Int. J. Pharm., 2008, 364, 328-43.