Hypermethylation of a cluster of Krüppel-type zinc finger protein genes on chromosome 19q13 in oropharyngeal squamous cell carcinoma

American Journal of Pathology

Volumn 178, Issue 5, 2011, Pages 1965-1974

  Lleras, Roberto A ^a   Adrien, Leslie R ^a   Smith, Richard V ^b   Brown, Benjamin ^a   Jivraj, Naheed ^a   Keller, Christopher ^a   Sarta, Cathy ^b   Schlecht, Nicolas F ^a   Harris, Thomas M ^a   Childs, Geoffrey ^a   Prystowsky, Michael B ^a   Belbin, Thomas J ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b MONTEFIORE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DINUCLEOTIDE; GENOMIC DNA; KRUPPEL LIKE FACTOR;

ADULT; AGED; ARTICLE; CHROMOSOME 19Q; CONTROLLED STUDY; CPG ISLAND; DISEASE SEVERITY; DNA METHYLATION; EPIGENETICS; FEMALE; GENE CLUSTER; GENE EXPRESSION; GENE LOCATION; GENE LOCUS; GENE SILENCING; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; MALE; MICROARRAY ANALYSIS; MOUTH MUCOSA; OROPHARYNX CARCINOMA; PRIMARY TUMOR; PRIORITY JOURNAL; RESPIRATORY TRACT MUCOSA; SQUAMOUS CELL CARCINOMA;

EID: 79959231779     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.01.049     Document Type: Article

References (39)

1. Ferlay J, Bray F, Pissani P, Parkin DM: GLOBOCAN 2000: cancer incidence, mortality and prevalence worldwide, version 1.0. IARC CancerBase 2001, No. 5. Lyon, IRAC Press, 2011
2. Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun MJ: Cancer statistics, 2007. CA Cancer J Clin 2007, 57:43-66
3. Takes RP, Baatenburg de Jong RJ, Schuuring E, Hermans J, Vis AA, Litvinov SV, van Krieken JH: Markers for assessment of nodal metastasis in laryngeal carcinoma. Arch Otolaryngol Head Neck Surg 1997, 123:412-419 (Pubitemid 27180942)
4. Gollin SM: Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease. Head Neck 2001, 23:238-253
5. Wreesmann VB, Singh B: Chromosomal aberrations in squamous cell carcinomas of the upper aerodigestive tract: biologic insights and clinical opportunities. J Oral Pathol Med 2005, 34:449-459 (Pubitemid 41153033)
6. Jones PA, Baylin SB: The fundamental role of epigenetic events in cancer. Nat Rev Genet 2002, 3:415-428 (Pubitemid 34587077)
7. Rosas SLB, Koch W, da Gloria da Costa Carvalho M, Wu L, Califano J, Westra W, Jen J, Sidransky D: Promoter hypermethylation patterns of p16. O6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients. Cancer Res 2001, 61:939-942
8. Maruya S, Issa JP, Weber RS, Rosenthal DI, Haviland JC, Lotan R, El-Naggar AK: Differential methylation status of tumor-associated genes in head and neck squamous carcinoma: incidence and potential implications. Clin Cancer Res 2004, 10:3825-3830 (Pubitemid 38697618)
9. Zuo C, Ai L, Ratliff P, Suen JY, Hanna E, Brent TP, Fan CY: O6- methylguanine-DNA methyltransferase gene: epigenetic silencing and prognostic value in head and neck squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev 2004, 13:967-975 (Pubitemid 38756707)
10. Ogi K, Toyota M, Ohe-Toyota M, Tanaka N, Noguchi M, Sonoda T, Kohama G, Tokino T: Aberrant methylation of multiple genes and clinicopathological features in oral squamous cell carcinoma. Clin Cancer Res 2002, 8:3164-3171 (Pubitemid 35155026)
11. Kudo Y, Kitajima S, Ogawa I, Hiraoka M, Sargolzaei S, Keikhaee MR, Sato S, Miyauchi M, Takata T: Invasion and metastasis of oral cancer cells require methylation of E-cadherin and/or degradation of membranous beta-catenin. Clin Cancer Res 2004, 10:5455-5463 (Pubitemid 39100483)
12. Calmon MF, Colombo J, Carvalho F, Souza FP, Filho JF, Fukuyama EE, Camargo AA, Caballero OL, Tajara EH, Cordeiro JA, Rahal P: Methylation profile of genes CDKN2A (p14 and p16). DAPK1, CDH1, and ADAM23 in head and neck cancer. Cancer Genet Cytogenet 2007, 173:31-37
13. Illumina, Inc.: Infinium Assay Methylation Protocol Guide. Catalog # WG-901-2701. Part # 11322371 Rev. A. 2008
14. Takai D, Jones PA: Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc Natl Acad Sci U S A 2002, 99:3740-3745 (Pubitemid 34252176)
15. Illumina Epigenetics TechNote: DNA Methylation Analysis. Pub. No. 270-2008-001. 2008
16. Bellefroid EJ, Lecocq PJ, Benhida A, Poncelet DA, Belayew A, Martial JA: The human genome contains hundreds of genes coding for finger proteins of the Krüppel type. DNA 1989, 8:377-387 (Pubitemid 19196421)
17. Ha PK, Califano JA: Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma. Lancet Oncol 2006, 7:77-82 (Pubitemid 43025396)
18. Costello JF, Plass C: Methylation matters. J Med Genet 2001, 38:285-303 (Pubitemid 32433981)
19. Baylin SB: DNA methylation and gene silencing in cancer. Nat Clin Pract Oncol 2005, 2(Suppl 1):S4-S11
20. Richards KL, Zhang B, Baggerly KA, Colella S, Lang JC, Schuller DE, Krahe R: Genome-wide hypomethylation in head and neck cancer is more pronounced in HPV-negative tumors and is associated with genomic instability. PLoS One 2009, 4:e4941
21. Bennett KL, Lee W, Lamarre E, Zhang X, Seth R, Scharpf J, Hunt J, Eng C: HPV status-independent association of alcohol and tobacco exposure or prior radiation therapy with promoter methylation of FUSSEL18. EBF3, IRX1, and SEPT9, but not SLC5A8, in head and neck squamous cell carcinomas. Genes Chromosomes Cancer 2010, 49:319-326
22. Morey Kinney SR, Smiraglia DJ, James SR, Moser MT, Foster BA, Karpf AR: Stage-specific alterations of DNA methyltransferase expression, DNA hypermethylation, and DNA hypomethylation during prostate cancer progression in the transgenic adenocarcinoma of mouse prostate model. Mol Cancer Res 2008, 6:1365-1374
23. Shannon M, Ashworth LK, Mucenski ML, Lamerdin JE, Branscomb E, Stubbs L: Comparative analysis of a conserved zinc finger gene cluster on human chromosome 19q and mouse chromosome 7. Genomics 1996, 33:112-120
24. Rousseau-Merck MF, Koczan D, Legrand I, Möller S, Autran S, Thiesen HJ: The KOX zinc finger genes: genome wide mapping of 368 ZNF PAC clones with zinc finger gene clusters predominantly in 23 chromosomal loci are confirmed by human sequences annotated in EnsEMBL. Cytogenet Genome Res 2002, 98:147-153 (Pubitemid 37465008)
25. Hoffman SMG, Amemiya C, Mohrenweiser HW: Distribution and Organization of Zinc Finger Genes on Chromosome 19. Report of the D.O.E. Human Genome Program Contractor-Grantee Workshop IV, NM. November 13-17, 1994, p. 49
26. Urrutia R: KRAB-containing zinc-finger repressor proteins. Genome Biol 2003, 4:231
27. Oka D, Yamashita S, Tomioka T, Nakanishi Y, Kato H, Kaminishi M, Ushijima T: The presence of aberrant DNA methylation in noncancerous esophageal mucosae in association with smoking history: a target for risk diagnosis and prevention of esophageal cancers. Cancer 2009, 115:3412-3426
28. Yamashita S, Tsujino Y, Moriguchi K, Tatematsu M, Ushijima T: Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2′-deoxycytidine treatment and oligonucleotide microarray. Cancer Sci 2006, 97:64-71 (Pubitemid 43257029)
29. Omura N, Li CP, Li A, Hong SM, Walter K, Jimeno A, Hidalgo M, Goggins M: Genome-wide profiling of methylated promoters in pancreatic adenocarcinoma. Cancer Biol Ther 2008, 7:1146-1156
30. Xiang Z, Yuan W, Luo N, Wang Y, Tan K, Deng Y, Zhou X, Zhu C, Li Y, Liu M, Wu X, Li Y: A novel human zinc finger protein ZNF540 interacts with MVP and inhibits transcriptional activities of the ERK signal pathway. Biochem Biophys Res Commun 2006, 347:288-296 (Pubitemid 44026490)
31. Huang X, Yuan W, Huang W, Bai Y, Deng Y, Zhu C, Liang P, Li Y, Du X, Liu M, Wang Y, Wu X: ZNF569, a novel KRAB-containing zinc finger protein, suppresses MAPK signaling pathway. Biochem Biophys Res Commun 2006, 346:621-628
32. Cheng Y, Geng H, Cheng SH, Liang P, Bai Y, Li J, Srivastava G, Ng MH, Fukagawa T, Wu X, Chan AT, Tao Q: KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas. Cancer Res 2010, 70:6516-6526
33. Silveira NJ, Varuzza L, Machado-Lima A, Lauretto MS, Pinheiro DG, Rodrigues RV, Severino P, Nobrega FG, Silva WA Jr, de B Pereira CA, Tajara EH: Searching for molecular markers in head and neck squamous cell carcinomas (HNSCC) by statistical and bioinformatic analysis of larynx-derived SAGE libraries. BMC Med Genomics 2008, 1:56
34. Cai D, Cao J, Li Z, Zheng X, Yao Y, Li W, Yuan Z: Up-regulation of bone marrow stromal protein 2 (BST2) in breast cancer with bone metastasis. BMC Cancer 2009, 9:102
35. Ha H, Barnoski BL, Sun L, Emanuel BS, Burrows PD: Structure, chromosomal localization, and methylation pattern of the human mb-1 gene. J Immunol 1994, 152:5749-5757 (Pubitemid 24174154)
36. Denicola G, Tuveson DA: VAV1: a new target in pancreatic cancer? Cancer Biol Ther 2005, 4:509-511
37. Lane J, Martin TA, Mansel RE, Jiang WG: The expression and prognostic value of the guanine nucleotide exchange factors (GEFs) Trio, Vav1 and TIAM-1 in human breast cancer. Int Semin Surg Oncol 2008, 5:23
38. Nam RK, Zhang WW, Trachtenberg J, Diamandis E, Toi A, Emami M, Ho M, Sweet J, Evans A, Jewett MA, Narod SA: Single nucleotide polymorphism of the human kallikrein-2 gene highly correlates with serum human kallikrein-2 levels and in combination enhances prostate cancer detection. J Clin Oncol 2003, 21:2312-2319 (Pubitemid 46621869)
39. Yousef GM, Scorilas A, Katsaros D, Fracchioli S, Iskander L, Borgono C, Rigault de la Longrais IA, Puopolo M, Massobrio M, Diamandis EP: Prognostic value of the human kallikrein gene 15 expression in ovarian cancer. J Clin Oncol 2003, 21:3119-3126 (Pubitemid 46606293)