Broad-spectrum immunosuppression by classless monocytes in non-Hodgkin's lymphoma

Immunotherapy

Volumn 3, Issue 6, 2011, Pages 723-726

  Vari, Frank ^a   Gandhi, Maher K ^a,b  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b PRINCESS ALEXANDRA HOSPITAL   (Australia)

Author keywords

arginine; HLA DR; immunosuppression; monocyte; non Hodgkin lymphoma; tolerance

Indexed keywords

ARGINASE 1; ARGININE; CD14 ANTIGEN; CD83 ANTIGEN; GAMMA INTERFERON; HLA DR ANTIGEN; INFLUENZA VACCINE; TETANUS TOXOID; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR 2;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; CYTOKINE PRODUCTION; DENDRITIC CELL; ENZYME BLOOD LEVEL; FOLLICULAR LYMPHOMA; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LARGE CELL LYMPHOMA; LYMPHOCYTE PROLIFERATION; LYMPHOCYTOMA; MANTLE CELL LYMPHOMA; MONOCYTE; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METABOLISM;

EID: 79959214021     PISSN: 1750743X     EISSN: 17507448     Source Type: Journal    
DOI: 10.2217/imt.11.56     Document Type: Article

References (19)

1. +HLA-DRlow/- monocytes in B-cell non-Hodgkin lymphoma. Blood 117(3), 872-881 (2011).
2. Florescu A, Amir E, Bouganim N, Clemons M: Immune therapy for breast cancer in 2010 - hype or hope? Curr. Oncol. 18(1), E9-E18 (2011).
3. Palucka K, Ueno H, Banchereau J: Recent developments in cancer vaccines. J. Immunol. 186(3), 1325-1331 (2011).
4. + regulatory T-cell population by non-Hodgkin lymphoma. Blood 111(11), 5359-5370 (2008).
5. Schmielau J, Finn OJ: Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of T-cell function in advanced cancer patients. Cancer Res. 61(12), 4756-4760 (2001). (Pubitemid 32691887)
6. Steidl C, Lee T, Shah SP et al.: Tumorassociated macrophages and survival in classic Hodgkin's lymphoma. N. Engl. J. Med. 362(10), 875-885 (2010).
7. Talmadge JE: Pathways mediating the expansion and immunosuppressive activity of myeloid-derived suppressor cells and their relevance to cancer therapy. Clin. Cancer Res. 13(18 Pt 1), 5243-5248 (2007). (Pubitemid 47510346)
8. Ostrand-Rosenberg S: Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity. Cancer Immunol. Immunother. 59(10), 1593-1600 (2010).
9. Gabrilovich DI, Nagaraj S: Myeloid-derived suppressor cells as regulators of the immune system. Nat. Rev. Immunol. 9(3), 162-174 (2009).
10. Filipazzi P, Valenti R, Huber V et al.: Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine. J. Clin. Oncol. 25(18), 2546-2553 (2007). (Pubitemid 47041228)
11. Gordon IO, Freedman RS: Defective antitumor function of monocyte-derived macrophages from epithelial ovarian cancer patients. Clin. Cancer Res. 12(5), 1515-1524 (2006).
12. + T cells. Gastroenterology 135(1), 234-243 (2008). (Pubitemid 351899008)
13. +HLA-DRlow/- monocytes in prostate cancer. Prostate 70(4), 443-455 (2010).
14. Landelle C, Lepape A, Voirin N et al.: Low monocyte human leukocyte antigen-DR is independently associated with nosocomial infections after septic shock. Intensive Care Med. 36(11), 1859-1866 (2010).
15. Ju X, Zenke M, Hart DN, Clark GJ: CD300a/c regulate type I interferon and TNF-α secretion by human plasmacytoid dendritic cells stimulated with TLR7 and TLR9 ligands. Blood 112(4), 1184-1194 (2008).
16. Serafini P, Mgebroff S, Noonan K, Borrello I: Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells. Cancer Res. 68(13), 5439-5449 (2008).
17. Rodrigues JC, Gonzalez GC, Zhang L et al.: Normal human monocytes exposed to glioma cells acquire myeloid-derived suppressor cell-like properties. Neuro. Oncol. 12(4), 351-365 (2010).
18. Kedzierska K, Paukovics G, Handley A et al.: Interferon-γ therapy activates human monocytes for enhanced phagocytosis of Mycobacterium avium complex in HIVinfected individuals. HIV Clin. Trials 5(2), 80-85 (2004). (Pubitemid 38697082)
19. Boelens PG, Houdijk AP, Fonk JC et al.: Glutamine-enriched enteral nutrition increases HLA-DR expression on monocytes of trauma patients. J. Nutr. 132(9), 2580-2586 (2002). (Pubitemid 35013237)