Near-critical fluid micellization for high and efficient drug loading: Encapsulation of paclitaxel into PEG-b-PCL micelles

Journal of Physical Chemistry C

Volumn 115, Issue 24, 2011, Pages 11951-11956

  Tyrrell, Zachary L ^a   Shen, Youqing ^b   Radosz, MacIej ^a  

^a UNIVERSITY OF WYOMING   (United States)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICANCER DRUG; BURST RELEASE; CAPROLACTONE; CONVENTIONAL METHODS; CRITICAL REGION; DIMETHYL ETHERS; DRUG LOADING; ENCAPSULATION METHODS; HIGH EFFICIENCY; LOADING EFFICIENCY; MICELLAR SOLUTION; NEAR-CRITICAL FLUIDS; PACLITAXEL; POLYMERIC MICELLE; THERAPEUTIC EFFICACY; TRIFLUOROMETHANE;

EFFICIENCY; ETHERS; ETHYLENE; FLUIDS; FUELS; FUNCTIONAL POLYMERS; GLYCOLS; INCOMPRESSIBLE FLOW; LOADING; MICELLES; MICELLIZATION; POLYETHYLENE GLYCOLS; WASTE TREATMENT;

STRESS ANALYSIS;

EID: 79959209878     PISSN: 19327447     EISSN: 19327455     Source Type: Journal    
DOI: 10.1021/jp202335r     Document Type: Article

References (25)

1. Alakhov, V.; Moskaleva, E.; Batrakova, E.; Kabanov, A. Hypersensitization of multidrug resistant human ovarian carcinoma cells by pluronic P85 block copolymer Bioconjugate Chem. 1996, 7, 209-216
2. Gref, R.; Minamitake, Y.; Peracchia, M.; Trubetskoy, V.; Torchilin, V.; Langer, R. Biodegradable long-circulating polymeric nanospheres Science 1994, 263, 1600-1603 (Pubitemid 24128361)
3. Kabanov, A.; Alakhov, V. Micelles of Amphiphilic Block Copolymers as Vehicles for Drug Delivery; Elsevier: Dordrecht, 1997.
4. Kabanov, A.; Nazarova, I.; Astafieva, I.; Batrakova, E.; Alakhov, V.; Yarostavov, A.; Kabanov, V. Micelle formation and solubilization of fluorescent probes in poly(oxyethylene-b-oxypropylene-b-oxyethylene) Macromolecules 1995, 28, 2303-2314
5. Kataoka, K.; Kwon, G.; Yokoyama, M.; Okano, T. Block copolymer micelles as vehicles for drug delivery J. Controlled Release 1992, 24, 119-132 (Pubitemid 23161325)
6. Kwon, G.; Naito, M.; Yokoyama, M.; Okano, T.; Sakurai, Y.; Kataoka, K. Block copolymer micelles for drug delivery: loading and release of doxorubicin J. Controlled Release 1997, 48, 195-201 (Pubitemid 27401978)
7. La, S.; Okano, T.; Kataoka, K. Preparation and characterization of the micelle-forming polymeric drug indomethacin-incorporated poly(ethylene oxide)-poly(-benzyl L-aspartate) block copolymer micelles J. Pharm. Sci. 1996, 85, 85-90 (Pubitemid 26029075)
8. Aliabadi, H.; Mahmud, A.; Sharifabadi, A.; Lavasanifar, A. Micelles of methoxy poly(ethylene oxide)-b-poly(-caprolactone) as vehicles for the solubilization and controlled delivery of cyclosporine A J. Controlled Release 2005, 104 (2) 301-311 (Pubitemid 40724931)
9. Allen, C.; Yu, Y.; Maysinger, D.; Eisenberg, A. Polycaprolactone-b- poly(ethylene oxide) block copolymer micelles as a novel drug delivery vehicle for neurotrophic agents FK506 and L-685,818 Bioconjugate Chem. 1998, 9 (5) 564-572
10. Gaucher, G.; Dufresne, M.; Sant, V.; Kang, N.; Maysinger, D.; Leroux, J. C. Block copolymer micelles: preparation, characterization and application in drug delivery J. Controlled Release 2005, 109, 169-188 (Pubitemid 41742123)
11. Jette, K.; Law, D.; Schmitt, E.; Kwon, G. S. Preparation and drug loading of poly(ethylene glycol)-block-poly(ε-caprolactone) micelles through the evaporation of a cosolvent azeotrope Pharm. Res. 2004, 21 (7) 1184-1191 (Pubitemid 38954202)
12. Shuai, X.; Ai, H.; Nasongkla, N.; Kim, S.; Gao, J. Micellar carriers based on block copolymers of poly(-caprolactone) and poly(ethylene glycol) for doxorubicin delivery J. Controlled Release 2004, 98 (3) 415-426 (Pubitemid 39093952)
13. Vangeyte, P.; Gautier, S.; Jerome, R. About the methods of preparation of poly(ethylene oxide)-b-poly(ε-caprolactone) nanoparticles in water: Analysis by dynamic light scattering Colloids Surf., A 2004, 242, 203-211 (Pubitemid 38981591)
14. Tyrrell, Z.; Shen, Y.; Radosz, M. Fabrication of micellar nanoparticles for drug delivery through the self-assembly of block copolymers Prog. Polym. Sci. 2010, 35, 1128-1143
15. Shuai, X.; Merdan, T.; Schaper, A.; Xi, F.; Kissel, T. Core-cross-linked polymeric micelles as paclitaxel carriers Bioconjugate Chem. 2004, 15 (3) 441-448 (Pubitemid 38657848)
16. Radosz, M.; Shen, Y. International Patent WO 2008/030473 A2, 2008.
17. Winoto, W.; Adidharma, H.; Radosz, M. Micellization temperature and pressure for polystyrene-block-polyisoprene in subcritical and supercritical propane Macromolecules 2006, 39, 8140-8144 (Pubitemid 44865755)
18. Tyrrell, Z.; Winoto, W.; Shen, Y.; Radosz, M. Block copolymer micelles formed in supercritical fluid can become water-dispensable nanoparticles: Poly(ethylene glycol)-block-poly(ε-caprolactone) in trifluoromethane Ind. Eng. Chem. Res. 2009, 48, 1928-1932
19. Green, J.; Tyrrell, Z.; Radosz, M. Micellization of poly(ethylene glycol)-block-polycaprolactone in compressible near-critical solvents J. Phys. Chem. C 2010, 114, 16082-16086
20. Åuszczyk, M.; Radosz, M. Temperature- and pressure-induced crystallization and melting of tetracontane in propane: evidence of retrograde crystallization J. Chem. Eng. Data 2003, 48, 226-230
21. Chan, A.; Russo, P.; Radosz, M. Fluid-liquid equilibria in poly(ethylene-co-hexene-1)+propane: a light-scattering probe of cloud-point pressure and critical polymer concentration Fluid Phase Equilib. 2000, 173, 149-158 (Pubitemid 32475889)
22. Elhasi, S.; Astenah, R.; Lavasanifar, A. Solubilization of an amphiphilic drug by poly(ethylene oxide)-block-poly(ester) micelles Eur. J. Pharm. Biopharm. 2007, 65 (3) 406-413
23. Gadelle, F.; Koros, W.; Schechter, R. Solubilization of aromatic solutes in block copolymers Macromolecules 1995, 28 (14) 4883-4892
24. Xing, L.; Mattice, W. Strong solubilization of small molecules by triblock-copolymer micelles in selective solvents Macromolecules 1997, 30 (6) 1711-1717 (Pubitemid 127574475)
25. Hruby, M.; Konak, C.; Ulbrich, K. Polymeric micellar pH-sensitive drug delivery system for doxorubicin J. Controlled Release 2005, 103 (1) 137-148 (Pubitemid 40248568)