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Volumn 13, Issue 6, 2011, Pages 739-752

Uptake of antigens from modified vaccinia Ankara virus-infected leukocytes enhances the immunostimulatory capacity of dendritic cells

Author keywords

allogeneic stem cell transplantation; antigen presenting cells; dendritic cells; modified vaccinia Ankara; vaccine

Indexed keywords

CHEMOKINE RECEPTOR CCR7; CYTOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMEDIATE EARLY PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12P35; INTERLEUKIN 1BETA; INTERLEUKIN 6; MODIFIED VACCINIA VIRUS ANKARA VACCINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRUS VACCINE;

EID: 79959198504     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.3109/14653249.2010.549123     Document Type: Article
Times cited : (19)

References (61)
  • 1
    • 0016721708 scopus 로고
    • Abstammung, Eigenschaften und Verwendung des attenuierten Vaccinia-Stammes MVA
    • Mayr A, Hochstein-MintzeI V, Stickl H. Abstammung, Eigenschaften und Verwendung des attenuierten Vaccinia-Stammes MVA. Infection. 1975;3:6-14.
    • (1975) Infection , vol.3 , pp. 6-14
    • Mayr, A.1    Hochstein-MintzeI, V.2    Stickl, H.3
  • 2
    • 0031585552 scopus 로고    scopus 로고
    • Host range and cytopathogenicity of the highly attenuated MVA strain of vaccinia virus: Propagation and generation of recombinant viruses in a nonhuman mammalian cell line
    • DOI 10.1006/viro.1997.8845
    • Carroll MW, Moss B. Host range and cytopathogenicity of the highly attenuated MVA strain of vaccinia virus: propagation and generation of recombinant viruses in a nonhuman mammalian cell line. Virology. 1997;238:198-211. (Pubitemid 28218138)
    • (1997) Virology , vol.238 , Issue.2 , pp. 198-211
    • Carroll, M.W.1    Moss, B.2
  • 3
    • 0031974691 scopus 로고    scopus 로고
    • Highly attenuated modified vaccinia virus Ankara replicates in baby hamster kidney cells, a potential host for virus propagation, but not in various human transformed and primary cells
    • Drexler I, Heller K, Wahren B, Erfle V, Sutter G. Highly attenuated modified vaccinia virus Ankara replicates in baby hamster kidney cells, a potential host for virus propagation, but not in various human transformed and primary cells. J Gen Virol. 1998;79:347-52. (Pubitemid 28048439)
    • (1998) Journal of General Virology , vol.79 , Issue.2 , pp. 347-352
    • Drexler, I.1    Heller, K.2    Wahren, B.3    Erfle, V.4    Sutter, G.5
  • 4
    • 0025876805 scopus 로고
    • Mapping of deletions in the genome of the highly attenuated vaccinia virus MVA and their influence on virulence
    • Meyer H, Sutter G, Mayr A. Mapping of deletions in the genome of the highly attenuated vaccinia virus MVA and their influence on virulence. J Gen Virol. 1991;72:1031-8.
    • (1991) J Gen Virol , vol.72 , pp. 1031-1038
    • Meyer, H.1    Sutter, G.2    Mayr, A.3
  • 5
    • 0024601044 scopus 로고
    • Partial deletion of the human host range gene in the attenuated vaccinia virus MVA
    • DOI 10.1007/BF01311113
    • Altenburger W, Suter CP, Altenburger J. Partial deletion of the human host range gene in the attenuated vaccinia virus MVA. Arch Virol. 1989;105:15-27. (Pubitemid 19128945)
    • (1989) Archives of Virology , vol.105 , Issue.1-2 , pp. 15-27
    • Altenburger, W.1    Suter, C.-P.2    Altenburger, J.3
  • 6
    • 0032503233 scopus 로고    scopus 로고
    • The complete genomic sequence of the modified vaccinia Ankara strain: Comparison with other orthopoxviruses
    • DOI 10.1006/viro.1998.9123
    • Antoine G, Scheiflinger F, Dorner F, Falkner FG. The complete genomic sequence of the modified vaccinia Ankara strain: comparison with other orthopoxviruses. Virology. 1998;244:365-96. (Pubitemid 28384101)
    • (1998) Virology , vol.244 , Issue.2 , pp. 365-396
    • Antoine, G.1    Scheiflinger, F.2    Dorner, F.3    Falkner, F.G.4
  • 7
    • 0018200779 scopus 로고
    • Vaccination against pox diseases under immunosuppressive conditions
    • Mayr A, Danner K. Vaccination against pox diseases under immunosuppressive conditions. Dev Biol Stand. 1978;41: 225-34. (Pubitemid 9104710)
    • (1978) Developments in Biological Standardization , vol.VOL. 41 , pp. 225-234
    • Mayr, A.1    Danner, K.2
  • 8
    • 0016400312 scopus 로고
    • MVA vaccination against smallpox: Clinical tests with an attenuated live vaccinia virus strain (MVA) (author transl)
    • Stickl H, Hochstein-Mintzel V, Mayr A, Huber HC, Schafer H, Holzner A. [MVA vaccination against smallpox: clinical tests with an attenuated live vaccinia virus strain (MVA) (author transl)]. Dtsch Med Wochenschr. 1974;99:2386-92.
    • (1974) Dtsch Med Wochenschr , vol.99 , pp. 2386-2392
    • Stickl, H.1    Hochstein-Mintzel, V.2    Mayr, A.3    Huber, H.C.4    Schafer, H.5    Holzner, A.6
  • 10
    • 0026442276 scopus 로고
    • Nonreplicating vaccinia vector efficiently expresses recombinant genes
    • Sutter G, Moss B. Nonreplicating vaccinia vector efficiently expresses recombinant genes. Proc Natl Acad Sci USA. 1992;89:10847-51.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10847-10851
    • Sutter, G.1    Moss, B.2
  • 11
    • 56649097350 scopus 로고    scopus 로고
    • Safety and immunogenicity of recombinant poxvirus HIV-1 vaccines in young adults on highly active antiretroviral therapy
    • Greenough TC, Cunningham CK, Muresan P, McManus M, Persaud D, Fenton T, et al. Safety and immunogenicity of recombinant poxvirus HIV-1 vaccines in young adults on highly active antiretroviral therapy. Vaccine. 2008;26: 6883-93.
    • (2008) Vaccine , vol.26 , pp. 6883-6893
    • Greenough, T.C.1    Cunningham, C.K.2    Muresan, P.3    McManus, M.4    Persaud, D.5    Fenton, T.6
  • 13
    • 60549106426 scopus 로고    scopus 로고
    • Phase II trial of modified vaccinia Ankara (MVA) virus expressing 5T4 and high dose interleukin-2 (IL-2) in patients with metastatic renal cell carcinoma
    • Kaufman HL, Taback B, Sherman W, Kim DW, Shingler WH, Moroziewicz D, et al. Phase II trial of modified vaccinia Ankara (MVA) virus expressing 5T4 and high dose interleukin-2 (IL-2) in patients with metastatic renal cell carcinoma. J Transl Med. 2009;7:2.
    • (2009) J Transl Med , vol.7 , pp. 2
    • Kaufman, H.L.1    Taback, B.2    Sherman, W.3    Kim, D.W.4    Shingler, W.H.5    Moroziewicz, D.6
  • 14
    • 33644837630 scopus 로고    scopus 로고
    • Vaccine immunotherapy with MVA-Muc1- IL2 (TG4010) in prostate cancer patients with biochemical failure
    • ASCO Annual Meeting Proceedings
    • Dreicer R, Ahman R, Pantuck A, Stadler WM, Bizouarne N, Derbij BA, et al. Vaccine immunotherapy with MVA-Muc1- IL2 (TG4010) in prostate cancer patients with biochemical failure. ASCO Annual Meeting Proceedings. J Clin Oncol. 2005;23:4581.
    • (2005) J Clin Oncol , vol.23 , pp. 4581
    • Dreicer, R.1    Ahman, R.2    Pantuck, A.3    Stadler, W.M.4    Bizouarne, N.5    Derbij, B.A.6
  • 15
    • 42649138944 scopus 로고    scopus 로고
    • Vaccination of colorectal cancer patients with TroVax given alongside chemotherapy (5-fluorouracil, leukovorin and irinotecan) is safe and induces potent immune responses
    • Harrop R, Drury N, Shingler W, Chikoti P, Redchenko I, Carroll MW, et al. Vaccination of colorectal cancer patients with TroVax given alongside chemotherapy (5-fluorouracil, leukovorin and irinotecan) is safe and induces potent immune responses. Cancer Immunol Immunother. 2008; 57:977-86.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 977-986
    • Harrop, R.1    Drury, N.2    Shingler, W.3    Chikoti, P.4    Redchenko, I.5    Carroll, M.W.6
  • 16
    • 50349090322 scopus 로고    scopus 로고
    • A phase II study of Tg4010 (Mva-Muc1-Il2) in association with chemotherapy in patients with stage III/IV non-small cell lung cancer
    • Ramlau R, Quoix E, Rolski J, Pless M, Lena H, Levy E, et al. A phase II study of Tg4010 (Mva-Muc1-Il2) in association with chemotherapy in patients with stage III/IV non-small cell lung cancer. J Thorac Oncol. 2008;3:735-44.
    • (2008) J Thorac Oncol , vol.3 , pp. 735-744
    • Ramlau, R.1    Quoix, E.2    Rolski, J.3    Pless, M.4    Lena, H.5    Levy, E.6
  • 18
    • 48749107581 scopus 로고    scopus 로고
    • Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa
    • Hawkridge T, Scriba TJ, Gelderbloem S, Smit E, Tameris M, Moyo S, et al. Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in healthy adults in South Africa. J Infect Dis. 2008;198:544-52.
    • (2008) J Infect Dis , vol.198 , pp. 544-552
    • Hawkridge, T.1    Scriba, T.J.2    Gelderbloem, S.3    Smit, E.4    Tameris, M.5    Moyo, S.6
  • 24
    • 67649338409 scopus 로고    scopus 로고
    • Recombinant modified vaccinia Ankara (MVA) effectively boosts DNA-primed HIV-specific immune responses in humans despite pre-existing vaccinia immunity
    • Gudmundsdotter L, Nilsson C, Brave A, Hejdeman B, Earl P, Moss B, et al. Recombinant modified vaccinia Ankara (MVA) effectively boosts DNA-primed HIV-specific immune responses in humans despite pre-existing vaccinia immunity. Vaccine. 2009;27:4468-74.
    • (2009) Vaccine , vol.27 , pp. 4468-4474
    • Gudmundsdotter, L.1    Nilsson, C.2    Brave, A.3    Hejdeman, B.4    Earl, P.5    Moss, B.6
  • 25
    • 0035815437 scopus 로고    scopus 로고
    • Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine
    • Amara RR, Villinger F, Altman JD, Lydy SL, O'Neil SP, Staprans SI, et al. Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine. Science. 2001;292:69-74.
    • (2001) Science , vol.292 , pp. 69-74
    • Amara, R.R.1    Villinger, F.2    Altman, J.D.3    Lydy, S.L.4    O'Neil, S.P.5    Staprans, S.I.6
  • 26
    • 22544471603 scopus 로고    scopus 로고
    • Vaccinia virus tropism for primary hematolymphoid cells is determined by restricted expression of a unique virus receptor
    • DOI 10.1128/JVI.79.16.10397-10407.2005
    • Chahroudi A, Chavan R, Kozyr N, Waller EK, Silvestri G, Feinberg MB. Vaccinia virus tropism for primary hematolymphoid cells is determined by restricted expression of a unique virus receptor. J Virol. 2005;79:10397-407. (Pubitemid 41098580)
    • (2005) Journal of Virology , vol.79 , Issue.16 , pp. 10397-10407
    • Chahroudi, A.1    Chavan, R.2    Koyzr, N.3    Waller, E.K.4    Silvestri, G.5    Feinberg, M.B.6
  • 27
    • 15744394459 scopus 로고    scopus 로고
    • Susceptibility of different leukocyte cell types to vaccinia virus infection
    • Sanchez-Puig JM, Sanchez L, Roy G, Blasco R. Susceptibility of different leukocyte cell types to vaccinia virus infection. Virol J. 2004;1:10.
    • (2004) Virol J , vol.1 , pp. 10
    • Sanchez-Puig, J.M.1    Sanchez, L.2    Roy, G.3    Blasco, R.4
  • 28
    • 42949155679 scopus 로고    scopus 로고
    • Dendritic cells are preferentially targeted among hematolymphocytes by modified vaccinia virus Ankara and play a key role in the induction of virus-specific T cell responses in vivo
    • Liu L, Chavan R, Feinberg MB. Dendritic cells are preferentially targeted among hematolymphocytes by modified vaccinia virus Ankara and play a key role in the induction of virus-specific T cell responses in vivo. BMC Immunol. 2008;9:15.
    • (2008) BMC Immunol , vol.9 , pp. 15
    • Liu, L.1    Chavan, R.2    Feinberg, M.B.3
  • 29
    • 4043142172 scopus 로고    scopus 로고
    • Modified vaccinia virus Ankara induces moderate activation of human dendritic cells
    • DOI 10.1099/vir.0.79998-0
    • Drillien R, Spehner D, Hanau D. Modified vaccinia virus Ankara induces moderate activation of human dendritic cells. J Gen Virol. 2004;85:2167-75. (Pubitemid 39162587)
    • (2004) Journal of General Virology , vol.85 , Issue.8 , pp. 2167-2175
    • Drillien, R.1    Spehner, D.2    Hanau, D.3
  • 30
    • 34547747839 scopus 로고    scopus 로고
    • Distinct gene expression profiling after infection of immature human monocyte-derived dendritic cells by the attenuated poxvirus vectors MVA and NYVAC
    • DOI 10.1128/JVI.00444-07
    • Guerra S, Najera JL, Gonzalez JM, Lopez-Fernandez LA, Climent N, Gatell JM, et al. Distinct gene expression profiling after infection of immature human monocyte-derived dendritic cells by the attenuated poxvirus vectors MVA and NYVAC. J Virol. 2007;81:8707-21. (Pubitemid 47242844)
    • (2007) Journal of Virology , vol.81 , Issue.16 , pp. 8707-8721
    • Guerra, S.1    Najera, J.L.2    Gonzalez, J.M.3    Lopez-Fernandez, L.A.4    Climent, N.5    Gatell, J.M.6    Gallart, T.7    Esteban, M.8
  • 31
    • 62749084521 scopus 로고    scopus 로고
    • Modified vaccinia virus Ankara triggers chemotaxis of monocytes and early respiratory immigration of leukocytes by induction of CCL2 expression
    • Lehmann MH, Kastenmuller W, Kandemir JD, Brandt F, Suezer Y, Sutter G. Modified vaccinia virus Ankara triggers chemotaxis of monocytes and early respiratory immigration of leukocytes by induction of CCL2 expression. J Virol. 2009;83:2540-52.
    • (2009) J Virol , vol.83 , pp. 2540-2552
    • Lehmann, M.H.1    Kastenmuller, W.2    Kandemir, J.D.3    Brandt, F.4    Suezer, Y.5    Sutter, G.6
  • 32
    • 33751376416 scopus 로고    scopus 로고
    • A novel source of viable peripheral blood mononuclear cells from leukoreduction system chambers
    • Dietz AB, Bulur PA, Emery RL, Winters JL, Epps DE, Zubair AC, et al. A novel source of viable peripheral blood mononuclear cells from leukoreduction system chambers. Transfusion. 2006;46:2083-9.
    • (2006) Transfusion , vol.46 , pp. 2083-2089
    • Dietz, A.B.1    Bulur, P.A.2    Emery, R.L.3    Winters, J.L.4    Epps, D.E.5    Zubair, A.C.6
  • 33
    • 34548720407 scopus 로고    scopus 로고
    • Recovery of white blood cells and platelets from leukoreduction system chambers of Trima Accel and COBE Spectra plateletpheresis devices
    • Strasser EF, Weidinger T, Zimmermann R, Ringwald J, Eckstein R. Recovery of white blood cells and platelets from leukoreduction system chambers of Trima Accel and COBE Spectra plateletpheresis devices. Transfusion. 2007;47: 1943-5.
    • (2007) Transfusion , vol.47 , pp. 1943-1945
    • Strasser, E.F.1    Weidinger, T.2    Zimmermann, R.3    Ringwald, J.4    Eckstein, R.5
  • 34
    • 34249112807 scopus 로고    scopus 로고
    • Characterization of mononuclear cells remaining in the leukoreduction system chambers of apheresis instruments after routine platelet collection: A new source of viable human blood cells
    • Neron S, Thibault L, Dussault N, Cote G, Ducas E, Pineault N, et al. Characterization of mononuclear cells remaining in the leukoreduction system chambers of apheresis instruments after routine platelet collection: a new source of viable human blood cells. Transfusion. 2007;47:1042-9.
    • (2007) Transfusion , vol.47 , pp. 1042-1049
    • Neron, S.1    Thibault, L.2    Dussault, N.3    Cote, G.4    Ducas, E.5    Pineault, N.6
  • 35
    • 34548094872 scopus 로고    scopus 로고
    • Dendritic cell vaccination in allogeneic stem cell recipients: Induction of human cytomegalovirus (HCMV)-specific cytotoxic T lymphocyte responses even in patients receiving a transplant from an HCMV-seronegative donor
    • DOI 10.1086/520538
    • Grigoleit GU, Kapp M, Hebart H, Fick K, Beck R, Jahn G, et al. Dendritic cell vaccination in allogeneic stem cell recipients: induction of human cytomegalovirus (HCMV)-specific cytotoxic T lymphocyte responses even in patients receiving a transplant from an HCMV-seronegative donor. J Infect Dis. 2007;196:699-704. (Pubitemid 47293851)
    • (2007) Journal of Infectious Diseases , vol.196 , Issue.5 , pp. 699-704
    • Grigoleit, G.U.1    Kapp, M.2    Hebart, H.3    Fick, K.4    Beck, R.5    Jahn, G.6    Einsele, H.7
  • 36
    • 0034091404 scopus 로고    scopus 로고
    • Transient host range selection for genetic engineering of modified vaccinia virus Ankara
    • Staib C, Drexler I, Ohlmann M, Wintersperger S, Erfle V, Sutter G. Transient host range selection for genetic engineering of modified vaccinia virus Ankara. Biotechniques. 2000;28: 1137-42, 44-6, 48.
    • (2000) Biotechniques , vol.28
    • Staib, C.1    Drexler, I.2    Ohlmann, M.3    Wintersperger, S.4    Erfle, V.5    Sutter, G.6
  • 37
    • 0030446387 scopus 로고    scopus 로고
    • Development of a replication-deficient recombinant vaccinia virus vaccine effective against parainfluenza virus 3 infection in an animal model
    • DOI 10.1016/S0264-410X(96)00072-2, PII S0264410X96000722
    • Wyatt LS, Shors ST, Murphy BR, Moss B. Development of a replication-deficient recombinant vaccinia virus vaccine effective against parainfluenza virus 3 infection in an animal model. Vaccine. 1996;14:1451-8. (Pubitemid 27008261)
    • (1996) Vaccine , vol.14 , Issue.15 , pp. 1451-1458
    • Wyatt, L.S.1    Shors, S.T.2    Murphy, B.R.3    Moss, B.4
  • 38
    • 0037388244 scopus 로고    scopus 로고
    • Improved host range selection for recombinant modified vaccinia virus Ankara
    • Staib C, Lowel M, Erfle V, Sutter G. Improved host range selection for recombinant modified vaccinia virus Ankara. Biotechniques. 2003;34:694-6, 8, 700.
    • (2003) Biotechniques , vol.34
    • Staib, C.1    Lowel, M.2    Erfle, V.3    Sutter, G.4
  • 39
    • 0025302978 scopus 로고
    • Transient dominant selection of recombinant vaccinia viruses
    • Falkner FG, Moss B. Transient dominant selection of recombinant vaccinia viruses. J Virol. 1990;64:3108-11. (Pubitemid 20171312)
    • (1990) Journal of Virology , vol.64 , Issue.6 , pp. 3108-3111
    • Falkner, F.G.1    Moss, B.2
  • 40
    • 0037683341 scopus 로고    scopus 로고
    • Automated RNA extraction by MagNA pure followed by rapid quantification of cytokine and chemokine gene expression with use of fluorescence resonance energy transfer
    • DOI 10.1373/49.6.955
    • Loeffler J, Swatoch P, Akhawi-Araghi D, Hebart H, Einsele H. Automated RNA extraction by MagNA Pure followed by rapid quantification of cytokine and chemokine gene expression with use of fluorescence resonance energy transfer. Clin Chem. 2003;49:955-8. (Pubitemid 36623477)
    • (2003) Clinical Chemistry , vol.49 , Issue.6 , pp. 955-958
    • Loeffler, J.1    Swatoch, P.2    Akhawi-Araghi, D.3    Hebart, H.4    Einsele, H.5
  • 41
    • 40949109798 scopus 로고    scopus 로고
    • Proinflammatory response of immature human dendritic cells is mediated by dectin-1 after exposure to Aspergillus fumigatus germ tubes
    • DOI 10.1086/528694
    • Mezger M, Kneitz S, Wozniok I, Kurzai O, Einsele H, Loeffler J. Proinflammatory response of immature human dendritic cells is mediated by dectin-1 after exposure to Aspergillus fumigatus germ tubes. J Infect Dis. 2008;197:924-31. (Pubitemid 351417017)
    • (2008) Journal of Infectious Diseases , vol.197 , Issue.6 , pp. 924-931
    • Mezger, M.1    Kneitz, S.2    Wozniok, I.3    Kurzai, O.4    Einsele, H.5    Loeffler, J.6
  • 42
    • 0141889279 scopus 로고    scopus 로고
    • + T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation
    • + T cells exist in healthy individuals and in patients with chronic myelogenous leukemia before and after stem cell transplantation. Blood. 2003;102: 2892-900.
    • (2003) Blood , vol.102 , pp. 2892-2900
    • Rezvani, K.1    Grube, M.2    Brenchley, J.M.3    Sconocchia, G.4    Fujiwara, H.5    Price, D.A.6
  • 43
    • 33645214733 scopus 로고    scopus 로고
    • In vitro expansion of polyclonal T-cell subsets for adoptive immunotherapy by recombinant modified vaccinia Ankara
    • La Rosa C, Wang Z, Lacey SF, Lalimarmo MM, Krishnan A, Longmate J, et al. In vitro expansion of polyclonal T-cell subsets for adoptive immunotherapy by recombinant modified vaccinia Ankara. Exp Hematol. 2006;34:497-507.
    • (2006) Exp Hematol , vol.34 , pp. 497-507
    • La Rosa, C.1    Wang, Z.2    Lacey, S.F.3    Lalimarmo, M.M.4    Krishnan, A.5    Longmate, J.6
  • 44
    • 35448974187 scopus 로고    scopus 로고
    • Cross-priming of cytotoxic T cells dictates antigen requisites for modified vaccinia virus Ankara vector vaccines
    • DOI 10.1128/JVI.00903-07
    • Gasteiger G, Kastenmuller W, Ljapoci R, Sutter G, Drexler I. Cross-priming of cytotoxic T cells dictates antigen requisites for modified vaccinia virus Ankara vector vaccines. J Virol. 2007;81:11925-36. (Pubitemid 47623824)
    • (2007) Journal of Virology , vol.81 , Issue.21 , pp. 11925-11936
    • Gasteiger, G.1    Kastenmuller, W.2    Ljapoci, R.3    Sutter, G.4    Drexler, I.5
  • 45
    • 33750088696 scopus 로고    scopus 로고
    • The highly attenuated vaccinia virus strain modified virus Ankara induces apoptosis in melanoma cells and allows bystander dendritic cells to generate a potent anti-tumoral immunity
    • DOI 10.1111/j.1365-2249.2006.03177.x
    • Greiner S, Humrich JY, Thuman P, Sauter B, Schuler G, Jenne L. The highly attenuated vaccinia virus strain modified virus Ankara induces apoptosis in melanoma cells and allows bystander dendritic cells to generate a potent anti-tumoral immunity. Clin Exp Immunol. 2006;146:344-53. (Pubitemid 44581351)
    • (2006) Clinical and Experimental Immunology , vol.146 , Issue.2 , pp. 344-353
    • Greiner, S.1    Humrich, J.Y.2    Thuman, P.3    Sauter, B.4    Schuler, G.5    Jenne, L.6
  • 46
    • 0342470981 scopus 로고    scopus 로고
    • Biology of attenuated modified vaccinia virus Ankara recombinant vector in mice: Virus fate and activation of B- And T-cell immune responses in comparison with the western reserve strain and advantages as a vaccine
    • DOI 10.1128/JVI.74.2.923-933.2000
    • Ramirez JC, Gherardi MM, Esteban M. Biology of attenuated modified vaccinia virus Ankara recombinant vector in mice: virus fate and activation of B-and T-cell immune responses in comparison with the Western Reserve strain and advantages as a vaccine. J Virol. 2000;74:923-33. (Pubitemid 30036229)
    • (2000) Journal of Virology , vol.74 , Issue.2 , pp. 923-933
    • Ramirez, J.C.1    Gherardi, M.M.2    Esteban, M.3
  • 47
    • 67650915065 scopus 로고    scopus 로고
    • Innate immune sensing of modifi ed vaccinia virus Ankara (MVA) is mediated by TLR2- TLR6, MDA-5 and the NALP3 inflammasome
    • Delaloye J, Roger T, Steiner-Tardivel QG, Le Roy D, Knaup Reymond M, Akira S, et al. Innate immune sensing of modifi ed vaccinia virus Ankara (MVA) is mediated by TLR2- TLR6, MDA-5 and the NALP3 inflammasome. PLoS Pathog. 2009;5:e1000480.
    • (2009) PLoS Pathog , vol.5
    • Delaloye, J.1    Roger, T.2    Steiner-Tardivel, Q.G.3    Le Roy, D.4    Knaup Reymond, M.5    Akira, S.6
  • 48
    • 52649167708 scopus 로고    scopus 로고
    • CD4 T cells: Fates, functions, and faults
    • Zhu J, Paul WE. CD4 T cells: fates, functions, and faults. Blood. 2008;112:1557-69.
    • (2008) Blood , vol.112 , pp. 1557-1569
    • Zhu, J.1    Paul, W.E.2
  • 49
    • 0030064036 scopus 로고    scopus 로고
    • Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit
    • Snijders A, Hilkens CM, van der Pouw Kraan TC, Engel M, Aarden LA, Kapsenberg ML. Regulation of bioactive IL-12 production in lipopolysaccharide- stimulated human monocytes is determined by the expression of the p35 subunit. J Immunol. 1996;156:1207-12. (Pubitemid 26048118)
    • (1996) Journal of Immunology , vol.156 , Issue.3 , pp. 1207-1212
    • Snijders, A.1    Hilkens, C.M.U.2    Van Der, P.K.T.C.T.M.3    Engel, M.4    Aarden, L.A.5    Kapsenberg, M.L.6
  • 50
    • 0035383783 scopus 로고    scopus 로고
    • Prostaglandin E(2) is a selective inducer of interleukin- 12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer
    • Kalinski P, Vieira PL, Schuitemaker JH, de Jong EC, Kapsenberg ML. Prostaglandin E(2) is a selective inducer of interleukin- 12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer. Blood. 2001;97: 3466-9.
    • (2001) Blood , vol.97 , pp. 3466-3469
    • Kalinski, P.1    Vieira, P.L.2    Schuitemaker, J.H.3    De Jong, E.C.4    Kapsenberg, M.L.5
  • 51
    • 0028819316 scopus 로고
    • Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity
    • Ling P, Gately MK, Gubler U, Stern AS, Lin P, Hollfelder K, et al. Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity. J Immunol. 1995;154:116-27.
    • (1995) J Immunol , vol.154 , pp. 116-127
    • Ling, P.1    Gately, M.K.2    Gubler, U.3    Stern, A.S.4    Lin, P.5    Hollfelder, K.6
  • 53
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity. 2000;13:715-25.
    • (2000) Immunity , vol.13 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3    Timans, J.C.4    Xu, Y.5    Hunte, B.6
  • 56
    • 25844527139 scopus 로고    scopus 로고
    • Prevention of IL-1 signaling attenuates airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma
    • DOI 10.1016/j.jaci.2005.07.008, PII S0091674905016453
    • Johnson VJ, Yucesoy B, Luster MI. Prevention of IL-1 signaling attenuates airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma. J Allergy Clin Immunol. 2005;116:851-8. (Pubitemid 41400551)
    • (2005) Journal of Allergy and Clinical Immunology , vol.116 , Issue.4 , pp. 851-858
    • Johnson, V.J.1    Yucesoy, B.2    Luster, M.I.3
  • 57
    • 33748879109 scopus 로고    scopus 로고
    • Adenovirus expressing interleukin-1 receptor antagonist alleviates allergic airway inflammation in a murine model of asthma
    • Wang CC, Fu CL, Yang YH, Lo YC, Wang LC, Chuang YH, et al. Adenovirus expressing interleukin-1 receptor antagonist alleviates allergic airway inflammation in a murine model of asthma. Gene Ther. 2006;13:1414-21.
    • (2006) Gene Ther , vol.13 , pp. 1414-1421
    • Wang, C.C.1    Fu, C.L.2    Yang, Y.H.3    Lo, Y.C.4    Wang, L.C.5    Chuang, Y.H.6
  • 58
    • 70349571184 scopus 로고    scopus 로고
    • Do studies in humans better depict Th17 cells?
    • Annunziato F, Romagnani S. Do studies in humans better depict Th17 cells? Blood. 2009;114:2213-9.
    • (2009) Blood , vol.114 , pp. 2213-2219
    • Annunziato, F.1    Romagnani, S.2
  • 59
    • 33745269769 scopus 로고    scopus 로고
    • Infection of human dendritic cells with recombinant vaccinia virus MVA reveals general persistence of viral early transcription but distinct maturation-dependent cytopathogenicity
    • DOI 10.1016/j.virol.2006.02.039, PII S0042682206001371
    • Kastenmuller W, Drexler I, Ludwig H, Erfle V, Peschel C, Bernhard H, et al. Infection of human dendritic cells with recombinant vaccinia virus MVA reveals general persistence of viral early transcription but distinct matura tion-dependent cytopathogenicity. Virology. 2006;350: 276-88. (Pubitemid 43928113)
    • (2006) Virology , vol.350 , Issue.2 , pp. 276-288
    • Kastenmuller, W.1    Drexler, I.2    Ludwig, H.3    Erfle, V.4    Peschel, C.5    Bernhard, H.6    Sutter, G.7
  • 60
    • 0032212605 scopus 로고    scopus 로고
    • Vaccinia virus-induced apoptosis in immature B lymphocytes: Role of cellular Bcl-2
    • DOI 10.1016/S0168-1702(98)00105-1, PII S0168170298001051
    • Baixeras E, Cebrian A, Albar JP, Salas J, Martinez AC, Vinuela E, et al. Vaccinia virus-induced apoptosis in immature B lymphocytes: role of cellular Bcl-2. Virus Res. 1998; 58:107-13. (Pubitemid 28546727)
    • (1998) Virus Research , vol.58 , Issue.1-2 , pp. 107-113
    • Baixeras, E.1    Cebrian, A.2    Albar, J.P.3    Salas, J.4    Martinez-A, C.5    Vinuela, E.6    Revilla, Y.7
  • 61
    • 77955329674 scopus 로고    scopus 로고
    • Modified vaccinia virus Ankara exerts potent immune modulatory activities in a murine model
    • Norder M, Becker PD, Drexler I, Link C, Erfle V, Guzman CA. Modified vaccinia virus Ankara exerts potent immune modulatory activities in a murine model. PLoS One.5: e11400.
    • PLoS One , vol.5
    • Norder, M.1    Becker, P.D.2    Drexler, I.3    Link, C.4    Erfle, V.5    Guzman, C.A.6


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