Characterization and quantification of amorphous material in milled and spray-dried salbutamol sulfate: A comparison of thermal, spectroscopic, and water vapor sorption approaches

Journal of Pharmaceutical Sciences

Volumn 100, Issue 8, 2011, Pages 3114-3129

  Grisedale, Louise C ^a   Jamieson, Matthew J ^b   Belton, Peter S ^a   Barker, Susan A ^a   Craig, Duncan Q M ^a  

^a UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Amorphous; Crystallinity; Materials science; Milling; Thermal analysis

Indexed keywords

SALBUTAMOL SULFATE;

AMORPHOUS MATERIAL; ARTICLE; CRYSTALLIZATION; DEVICE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG MANUFACTURE; DRUG STRUCTURE; GLASS TRANSITION TEMPERATURE; GRAVIMETRY; INFRARED SPECTROSCOPY; INTERMETHOD COMPARISON; MATERIAL STATE; MATERIALS; MILLING; QUANTITATIVE ANALYSIS; SPECTROMETER; SPRAY DRYING; WATER CONTENT; WATER VAPOR; X RAY POWDER DIFFRACTION;

EID: 79958852605     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22484     Document Type: Article

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