Apoptosis resistance of mucosal lymphocytes and IL-10 deficiency in patients with steroid-refractory Crohn's disease

Inflammatory Bowel Diseases

Volumn 17, Issue 7, 2011, Pages 1490-1500

  Santaolalla, Rebeca ^a   Mañé, Josep ^b,c   Pedrosa, Elisabet ^b,c   Lorén, Violeta ^b,c   Fernández Bañares, Fernando ^a   Mallolas, Josefa ^a   Carrasco, Anna ^a   Salas, Antonio ^a   Rosinach, Merc ^a   Forné, Montserrat ^a   Espinõs, Jorge C ^a   Loras, Carme ^a   Donovan, Michael ^d   Puig, Pere ^d   Mañosa, Miriam ^c,e   Gassull, Miquel A ^b   Viver, Josep M ^a   Esteve, Maria ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b FUNDACIÓ INSTITUT D INVESTIGACIÓ EN CIÈNCIES DE LA SALUT GERMANS TRIAS I PUJOL   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d Althia Advanced Laboratories of Translational Health   (Spain)

^e HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

Author keywords

Crohn's disease; IL 10; lymphocyte apoptosis resistance; steroid resistance

Indexed keywords

BIOLOGICAL MARKER; CASPASE 3; CORTICOSTEROID; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 1ALPHA; INTERLEUKIN 4; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CLINICAL ARTICLE; COLON BIOPSY; COLON MUCOSA; CONTROLLED STUDY; CORTICOSTEROID THERAPY; CROHN DISEASE; CYTOKINE PRODUCTION; ENDOSCOPIC BIOPSY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; ILEUM MUCOSA; IMMUNOFLUORESCENCE; IMMUNOPHENOTYPING; MACROPHAGE; MALE; MONONUCLEAR CELL; PLASMA CELL; PREDICTIVE VALUE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; T LYMPHOCYTE; TREATMENT DURATION; TREATMENT RESPONSE; ULCERATIVE COLITIS;

ADRENAL CORTEX HORMONES; ADULT; APOPTOSIS; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CROHN DISEASE; DRUG RESISTANCE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; FOLLOW-UP STUDIES; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOPHENOTYPING; IMMUNOPRECIPITATION; INTERLEUKIN-10; LYMPHOCYTES; MALE; MIDDLE AGED; MUCOUS MEMBRANE; PROGNOSIS; PROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SURVIVAL RATE;

EID: 79958821308     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.21507     Document Type: Article

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