In vitro and in vivo analysis of a biodegradable poly(lactide-co-glycolide) copolymer capsule and collagen composite system for antibiotics and bone cells delivery

Journal of Trauma - Injury, Infection and Critical Care

Volumn 70, Issue 6, 2011, Pages 1503-1509

  Ueng, Steve W N ^a,b   Yuan, Li Jen ^a,b   Lin, Song Shu ^a,c   Liu, Shih Jung ^c   Chan, Err Cheng ^c   Chen, Kuei Tien ^c   Lee, Mel S ^a,b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Collagen; Composite system; MSC; PLGA; Vancomycin

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM; COLLAGEN GEL; COLLAGEN TYPE 1; MESSENGER RNA; OSTEOCALCIN; POLYGLACTIN; TRANSCRIPTION FACTOR RUNX2; VANCOMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC THERAPY; ARTICLE; BIODEGRADABILITY; BONE CELL; BONE DEVELOPMENT; BONE INFECTION; CALCIUM BLOOD LEVEL; COMPETITIVE INHIBITION; CONTROLLED STUDY; DISK DIFFUSION; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG RELEASE; ENZYME ACTIVITY; FEMUR; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; MESENCHYMAL STEM CELL; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAPHYLOCOCCUS AUREUS; TRABECULAR BONE;

ALKALINE PHOSPHATASE; ANIMALS; BIOCOMPATIBLE MATERIALS; BONE AND BONES; CALCIUM; CAPSULES; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLLAGEN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMUR; LACTIC ACID; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, FLUORESCENCE; OSTEOGENESIS; OSTEOMYELITIS; POLYGLYCOLIC ACID; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STAINING AND LABELING; VANCOMYCIN;

EID: 79958814576     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e3181edb873     Document Type: Article

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