A novel solvent-free method for the manufacture of biodegradable antibiotic-capsules for a long-term drug release using compression sintering and ultrasonic welding techniques

Biomaterials

Volumn 26, Issue 22, 2005, Pages 4662-4669

  Liu, Shih Jung ^a   Tsai, Ying E ^a   Ueng, Steve Wen Neng ^b   Chan, Err Cheng ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Antibiotic capsules; Bacterial inhibition; Compression sintering; In vitro elution; PLGA; Ultrasonic welding

Indexed keywords

BIODEGRADATION; BONE; CONTROLLED DRUG DELIVERY; COPOLYMERS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SINTERING; ULTRASONIC WELDING;

BIODEGRADABLE CAPSULES; BONE INFECTION; LONG-TERM DRUG DELIVERY;

ANTIBIOTICS;

GENTAMICIN; POLYGLACTIN; VANCOMYCIN;

ARTICLE; BIODEGRADABILITY; CAMPRESSION SINTERING; CONCENTRATION RESPONSE; DRUG CAPSULE; DRUG DELIVERY SYSTEM; ELUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; SLOW DRUG RELEASE; ULTRASONIC WELDING; WELDING;

ANTI-BACTERIAL AGENTS; BIODEGRADATION, ENVIRONMENTAL; DELAYED-ACTION PREPARATIONS; GENTAMICINS; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, ELECTRON, SCANNING; SOLVENTS; VANCOMYCIN;

BACTERIA (MICROORGANISMS); PHOCIDAE;

EID: 13944274532     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2004.11.053     Document Type: Article

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