Infection and rheumatoid arthritis: Still an open question

Current Opinion in Rheumatology

Volumn 23, Issue 4, 2011, Pages 352-357

  Hitchon, Carol A ^a   El Gabalawy, Hani S ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

immunity; microbiome; periodontitis; porphyromonas; rheumatoid arthritis

Indexed keywords

CYCLIC CITRULLINATED PEPTIDE ANTIBODY; RHEUMATOID FACTOR;

ADAPTIVE IMMUNITY; ARTICLE; AUTOIMMUNITY; BACTEROIDES; EPSTEIN BARR VIRUS; HUMAN; INFECTION; INNATE IMMUNITY; INTESTINE FLORA; MICROFLORA; MYCOPLASMA FERMENTANS; PARVOVIRUS; PATHOGENESIS; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; PROTEUS MIRABILIS; RHEUMATOID ARTHRITIS; RISK FACTOR;

ARTHRITIS, RHEUMATOID; BACTERIAL INFECTIONS; COMMUNICABLE DISEASES; HUMANS; PERIODONTAL DISEASES;

EID: 79958799270     PISSN: 10408711     EISSN: 15316963     Source Type: Journal    
DOI: 10.1097/BOR.0b013e3283477b7b     Document Type: Article

References (38)

1. de Pablo P, Dietrich T, McAlindon TE. Association of periodontal disease and tooth loss with rheumatoid arthritis in the US population. J Rheumatol 2008; 35:70-76.
2. Rosenstein ED, Weissmann G, Greenwald RA. Porphyromonas gingivalis, periodontitis and rheumatoid arthritis. Med Hypotheses 2009; 73:457-458.
3. Liao F, Li Z, Wang Y, et al. Porphyromonas gingivalis may play an important role in the pathogenesis of periodontitis-associated rheumatoid arthritis. Med Hypotheses 2009; 72:732-735.
4. Wegner N, Wait R, Sroka A, et al. Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and alpha-enolase: implications for autoimmunity in rheumatoid arthritis. Arthritis Rheum 2010; 62:2662-2672.
5. Hitchon CA, Chandad F, Ferucci ED, et al. Antibodies to Porphyromonas gingivalis are associated with anticitrullinated protein antibodies in patients with rheumatoid arthritis and their relatives. J Rheumatol 2010; 37:1105-1112.
6. Mikuls TR, Payne JB, Reinhardt RA, et al. Antibody responses to Porphyromonas gingivalis (P. gingivalis) in subjects with rheumatoid arthritis and periodontitis. Int Immunopharmacol 2009; 9:38-42.
7. Okada M, Kobayashi T, Ito S, et al. Antibody responses to periodontopathic bacteria in relation to rheumatoid arthritis in Japanese adults. J Periodontol 2011. [Epub ahead of print]
8. Snir O, Widhe M, Hermansson M, et al. Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients. Arthritis Rheum 2010; 62:44-52.
9. Lundberg K, Kinloch A, Fisher BA, et al. Antibodies to citrullinated alpha-enolase peptide 1 are specific for rheumatoid arthritis and cross-react with bacterial enolase. Arthritis Rheum 2008; 58:3009-3019.
10. Mahdi H, Fisher BA, Kallberg H, et al. Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis. Nat Genet 2009; 41:1319-1324.
11. van der WD, Alemayehu WG, Verduijn W, et al. Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis. Nat Genet 2010; 42:814-816.
12. Bagaitkar J, Demuth DR, Daep CA, et al. Tobacco upregulates P. gingivalis fimbrial proteins which induce TLR2 hyposensitivity. PLoS One 2010; 5:e9323.
13. Barksby HE, Nile CJ, Jaedicke KM, et al. Differential expression of immuno-regulatory genes in monocytes in response to Porphyromonas gingivalis and Escherichia coli lipopolysaccharide. Clin Exp Immunol 2009; 156:479-487.
14. Hayashi C, Gudino CV, Gibson FC III, Genco CA. Review: pathogen-induced inflammation at sites distant from oral infection: bacterial persistence and induction of cell-specific innate immune inflammatory pathways. Mol Oral Microbiol 2010; 25:305-316.
15. Nile CJ, Barksby E, Jitprasertwong P, et al. Expression and regulation of interleukin-33 in human monocytes. Immunology 2010; 130:172-180.
16. Palmer G, Talabot-Ayer D, Lamacchia C, et al. Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis. Arthritis Rheum 2009; 60:738-749.
17. Bianchi ME. DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 2007; 81:1-5. (Pubitemid 46028489)
18. Rohner E, Detert J, Kolar P, et al. Induced apoptosis of chondrocytes by Porphyromonas gingivalis as a possible pathway for cartilage loss in rheumatoid arthritis. Calcif Tissue Int 2010; 87:333-340.
19. Pischon N, Rohner E, Hocke A, et al. Effects of Porphyromonas gingivalis on cell cycle progression and apoptosis of primary human chondrocytes. Ann Rheum Dis 2009; 68:1902-1907.
20. Martinez-Martinez RE, Bud-Mendoza C, Patino-Marin N, et al. Detection of periodontal bacterial DNA in serum and synovial fluid in refractory rheumatoid arthritis patients. J Clin Periodontol 2009; 36:1004-1010.
21. Moen K, Brun JG, Valen M, et al. Synovial inflammation in active rheumatoid arthritis and psoriatic arthritis facilitates trapping of a variety of oral bacterial DNAs. Clin Exp Rheumatol 2006; 24:656-663. (Pubitemid 46138797)
22. Bartold PM, Marino V, Cantley M, Haynes DR. Effect of Porphyromonas gingivalis-induced inflammation on the development of rheumatoid arthritis. J Clin Periodontol 2010; 37:405-411.
23. Newkirk MM, Zbar A, Baron M, Manges AR. Distinct bacterial colonization patterns of Escherichia coli subtypes associate with rheumatoid factor status in early inflammatory arthritis. Rheumatology (Oxford) 2010; 49:1311-1316.
24. Nielubowicz GR, Mobley HL. Host-pathogen interactions in urinary tract infection. Nat Rev Urol 2010; 7:430-441.
25. Ebringer A, Rashid T, Wilson C. Rheumatoid arthritis, Proteus, anti-CCP antibodies and Karl Popper. Autoimmun Rev 2010; 9:216-223.
26. Kawahito Y, Ichinose S, Sano H, et al. Mycoplasma fermentans glycolipid-antigen as a pathogen of rheumatoid arthritis. Biochem Biophys Res Commun 2008; 369:561-566.
27. da Rocha Sobrinho HM, Jarach R, da Silva NA, et al. Mycoplasmal lipid-associated membrane proteins and mycoplasma arthritidis mitogen recognition by serum antibodies from patients with rheumatoid arthritis. Rheumatol Int 2010. [Epub ahead of print]
28. Sato N, Oizumi T, Kinbara M, et al. Promotion of arthritis and allergy in mice by aminoglycoglycerophospholipid, a membrane antigen specific to Mycoplasma fermentans. FEMS Immunol Med Microbiol 2010; 59:33-41.
29. Rechnitzer H, Brzuszkiewicz E, Strittmatter A, et al. Genomic features and insights into the biology of mycoplasma fermentans. Microbiology 2011; 157:760-773.
30. Meron MK, Amital H, Shepshelovich D, et al. Infectious aspects and the etiopathogenesis of rheumatoid arthritis. Clin Rev Allergy Immunol 2010; 38:287-291.
31. Magnusson M, Brisslert M, Zendjanchi K, et al. Epstein-Barr virus in bone marrow of rheumatoid arthritis patients predicts response to rituximab treatment. Rheumatology (Oxford) 2010; 49:1911-1919.
32. Colmegna I, Berts-Grill N. Parvovirus B19: its role in chronic arthritis. Rheum Dis Clin North Am 2009; 35:95-110.
33. Lee YK, Mazmanian SK. Has the microbiota played a critical role in the evolution of the adaptive immune system? Science 2010; 330:1768-1773.
34. Round JL, O'Connell RM, Mazmanian SK. Coordination of tolerogenic immune responses by the commensal microbiota. J Autoimmun 2010; 34:J220-J225.
35. Lee YK, Menezes JS, Umesaki Y, Mazmanian SK. Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 2011; 108 Suppl 1:4615-4622.
36. Wu HJ, Ivanov II, Darce J, et al. Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity 2010; 32:815-827.
37. Saleh M, Trinchieri G. Innate immune mechanisms of colitis and colitis-associated colorectal cancer. Nat Rev Immunol 2011; 11:9-20.
38. Vaahtovuo J, Munukka E, Korkeamaki M, et al. Fecal microbiota in early rheumatoid arthritis. J Rheumatol 2008; 35:1500-1505.