Absorption of flavonoids from Abelmoschus manihot extract by in situ intestinal perfusion

Yaoxue Xuebao

Volumn 46, Issue 4, 2011, Pages 454-459

  Xue, Cai Fu ^a   Guo, Jian Ming ^a   Qian, Da Wei ^a   Duan, Jin Ao ^a   Shu, Yan ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Abelmoschus manihot flower; Flavonoid; Intestinal absorption in situ

Indexed keywords

ABELMOSCHUS MANIHOT EXTRACT; AGLYCONE; FLAVONOID; FLAVONOID GLYCOSIDE; GLYCOPROTEIN P; HYPERIN; ISOQUERCITRIN; MYRICETIN; PLANT EXTRACT; QUERCETIN 3' O GLUCOSIDE; UNCLASSIFIED DRUG; VERAPAMIL;

ARTICLE; DIFFUSION; DRUG ABSORPTION; DUODENUM; FLOWER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN SITU INTESTINAL RECIRCULATION; INTESTINE ABSORPTION; INTESTINE PERFUSION; JEJUNUM; NONHUMAN; REPERFUSION;

ABELMOSCHUS; ANIMALS; FLAVONOIDS; FLOWERS; INTESTINAL ABSORPTION; MALE; P-GLYCOPROTEINS; PERFUSION; PLANT EXTRACTS; PLANTS, MEDICINAL; QUERCETIN; RATS; RATS, SPRAGUE-DAWLEY; VERAPAMIL;

EID: 79958783273     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Xiong NN, Yu JY, Deng Y. 26 chyluria patients treated with the flower of Abelmoschus manihot and experiment [J]. Liaoning J Tradit Chin Med, 1996, 23: 232-233.
2. Yao YM, Li KJ. Inhibition effect of the flower of Abelmoschus manihot extraction on Diplococcus gonorrhoeae [J]. Jiangsu J Tradit Chin Med, 1994, 15: 43-44.
3. Gu HZ, Song JB. Progress of studies on Abelmoschus manihot (L.) Medic [J]. J Chin Med Mater, 1998, 21: 158-160.
4. Wang L, Wan XJ, Wang GD. Clinical conservation of treatment of Huang Kui capsule on chronic renal diseases [J]. Inf Tradit Chin Med, 2002, 19: 36-37.
5. Yu JY, Xiong NN, Guo HF, et al. Clinical observation on diabetic nephropathy treated with alcohol extraction of Abelmoschus manihot [J]. Chin J Integr Tradit Chin West Med, 1995, 15: 263-265.
6. Lai XY, Zhao YY, Liang H. Studies on chemical constituents of Abelmoschs manihot [J]. China J Chin Mater Med, 2006, 31: 1597-1600.
7. Huang JG, Si LQ, Zuo KY, et al. The inhibitory effect of Pluronicon P-glycoprote in drug pump [J]. Acta Pharm Sin, 2007, 42: 989-994.
8. Cai Q, Li Y, Huang YP. In situ absorption of self-microemulsifying soft capsule of volatile oil from rhizome of Ligusticum chuanxiong in rats' intestine [J]. Acta Pharm Sin, 2009, 44: 425-429.
9. Zhang Y, Jiang XH. Mechanism of intestinal absorption of tetrandrine in rats [J]. Chin Tradit Herb Drugs, 2007, 38: 224-228. (Pubitemid 46534057)
10. Crepy V, Morand C, Besson C, et al. Quercetin, but not its glycosides, is absorbed from the rat stomach [J]. J Agric Food Chem, 2002, 50: 618-621. (Pubitemid 34106688)
11. Chan LMS, Lowes S, Hirst BH. The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability [J]. Eur J Pharm Sci, 2004, 21: 25-51. (Pubitemid 38050202)
12. Evans AM. Influence of dietary components on the gastrointestinal metabolism and transport of drugs [J]. Ther Drug Monit, 2000, 22: 131-136. (Pubitemid 30083114)