Mechanism of intestinal absorption of tetrandrine in rats

Chinese Traditional and Herbal Drugs

Volumn 38, Issue 2, 2007, Pages 224-228

  Zhang, Ying ^a,b   Jiang, Xue Hua ^a  

^a SICHUAN UNIVERSITY   (China)

^b Sichuan Industrial Institute of Antibiotics   (China)

Author keywords

Absorption rate constants; Apparent permeability coefficient; In situ perfusion; Tetrandrine

Indexed keywords

PHENOLSULFONPHTHALEIN; TETRANDRINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLON; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DRUG ABSORPTION; DRUG DIFFUSION; DRUG HALF LIFE; DUODENUM; FIRST PASS EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ILEUM; INTESTINE ABSORPTION; INTESTINE MUCOSA PERMEABILITY; JEJUNUM; NONHUMAN; RAT; SMALL INTESTINE; ULTRAVIOLET RADIATION;

EID: 34047209299     PISSN: 02532670     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Wang H, Luo S D, Cai H S. Advances in research on pharmacology of tetrandrine [J]. Chin Pharm J 2000, 35(12): 800-802.
2. Zeng F D, Shaw D H, Ogilvie R I. Kinetic disposition and hemodynamic effects of tetrandrine in anesthetized dogs [J]. J Cardiovasc Pharmacol, 1985, 7(6): 1034-1039.
3. Lou J S, Zhang C L. Studies on pharmacokinetic of tetrandrine in rabbit [J]. Clin Tradit Herb Drugs 1993, 24(1): 24-26.
4. Lu B. Pharmaceutical Experiment [M]. Beijing: People's Medical Publishing House, 1994.
5. Yu W J, Cai Y B, Jiang L N. Determination of tetrandrine in Jinake by HPLC [J]. Chin J Mod Appl Pharm 1999, 16(4): 50-52.
6. You B G, Yang M S, Fan S L, et al. Intestinal absorption kinetics of nitrendipine in rats [J]. Chin Pharm J 2004, 39(3): 214-217.
7. 1 in rat intestine [J]. Chin Pharm J, 2006, 41 (14): 1097-1102.
8. Artursson P, Karlsson J. Correlation between oral drug absorption in human and apparent drug permeability coefficients in human intestinal epithelial (CaCo-2) cells [J]. Biochem Biophys Res Commun, 1991, 175(3): 880-885.