Expeditious convergent procedure for the preparation of bis(POC) prodrugs of new (E)-4-phosphono-but-2-en-1-yl nucleosides

Tetrahedron

Volumn 67, Issue 29, 2011, Pages 5319-5328

  Montagu, Aurélien ^a   Pradére, Ugo ^a   Roy, Vincent ^a   Nolan, Steven P ^b   Agrofoglio, Luigi A ^a  

^a UNIVERSITÉ D'ORLÉANS   (France)

^b UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

Acyclonucleoside phosphonates; Olefin cross metathesis; Prodrug

Indexed keywords

4 PHOSPHONO BUT 2 EN 1 YL NUCLEOSIDE DERIVATIVE; ACYCLONUCLEOSIDE PHOSPHONATE DERIVATIVE; ALKENE; ANTIVIRUS AGENT; NUCLEOSIDE DERIVATIVE; PHOSPHONIC ACID DERIVATIVE; RUTHENIUM; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CATALYSIS; CROSS COUPLING REACTION; CYTOTOXICITY; DEALKYLATION; DEPROTECTION REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; HELA CELL; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN CYTOMEGALOVIRUS; NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY; SUBSTITUTION REACTION; VACCINIA VIRUS; VARICELLA ZOSTER VIRUS; VERO CELL; VESICULAR STOMATITIS VIRUS;

EID: 79958770577     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2011.05.017     Document Type: Article

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