Microwave-assisted silylation-amination of uracil acyclonucleosides to 4-alkylamino-2(1H)-pyrimidinone analogues

Synthesis

Volumn , Issue 13, 2008, Pages 2127-2133

  Roy, Vincent ^a   Mieczkowski, Adam ^a   Topalis, Dimitri ^b   Berteina Raboin, Sabine ^b   Deville Bonne, Dominique ^b   Nolan, Steven P ^c   Agrofoglio, Luigi A ^a  

^a UNIVERSITÉ D'ORLÉANS   (France)

^b CNRS   (France)

^c INSTITUTE OF CHEMICAL RESEARCH OF CATALONIA ICIQ   (Spain)

Author keywords

Acyclic nucleoside phosphonates; Microwaves; Olefin crossmetathesis; Silylation amination

Indexed keywords

AMINES;

SILYLATION;

SILANES;

BOC N 4 BUTYL N 1 (4 DIMETHOXYPHOSPHINYLBUT 2 ENYL)CYTOSINE; N 1 (4 DIMETHOXYPHOSPHINYLBUT 2 ENYL)N 4 PENTYLCYTOSINE; N 1 CROTYL N 4 (3 FLUOROBENZYL)CYTOSINE; N 1 CROTYL N 4 CYCLOHEXYLCYTOSINE; N 1 CROTYL N 4 NONYLCYTOSINE; N 1 CROTYL N 4 PENTYLCYTOSINE; N 4 (3 CHLOROBENZYL) N 1 (4 DIMETHOXYPHOSPHINYLBUT 2 ENYL)CYTOSINE; N 4 (3 CHLOROBENZYL) N 1 CROTYLCYTOSINE; N 4 (3 CHLOROBENZYL) N 4 BOC N 1 (4 DIMETHOXYPHOSPHINYLBUT 2 ENYL)CYTOSINE; N 4 (3 CHLOROBENZYL) N 4 BOC N 1 CROTYLCYTOSINE; N 4 (3 FLUOROBENZYL) N 1 (4 DIMETHOXYPHOSPHINYLBUT 2 ENYL)CYTOSINE; N 4 BENZYL N 1 (4 DIMETHOXYPHOSPHINYLBUT 2 ENYL)CYTOSINE; N 4 BENZYL N 1 CROTYLCYTOSINE; N 4 BENZYL N 4 BOC 1 N CROTYLCYTOSINE; N 4 BENZYL N 4 BOC N 1 (DIMETHOXYPHOSPHINYLBUT 2 ENYL)CYTOSINE; N 4 BOC N 1 (4 DIMETHOXYPHOSPHINYLBUT 2 ENYL)N 4 NONYLCYTOSINE; N 4 BOC N 1 (4 DIMETHOXYPHOSPHINYLBUT 2 ENYL)N 4 PENTYLCYTOSINE; N 4 BOC N 1 CROTYL N 4 (3 FLUOROBENZYL)CYTOSINE; N 4 BOC N 1 CROTYL N 4 CYCLOHEXYLCYTOSINE; N 4 BOC N 1 CROTYL N 4 NONYLCYTOSINE; N 4 BOC N 1 CROTYL N 4 PENTYLCYTOSINE; N 4 BOC N 4 (3 FLUOROBENZYL) N 1 (4 DIMETHOXYPHOSPHINYLBUT 2 ENYL)CYTOSINE; N 4 BOC N 4 BUTYL N 1 CROTYLCYTOSINE; N 4 BOC N 4 CYCLOHEXYL N 1 (4 DIMETHOXYPHOSPHINYLBUT 2 ENYL)CYTOSINE; N 4 BUTYL N 1 (4 DIMETHOXYPHOSPHINYLBUT 2 ENYL)CYTOSINE; N 4 BUTYL N 1 CROTYLCYTOSINE; N 4 CYCLOHEXYL N 1 (4 DIMETHOXYPHOSPHINYLBUT 2 ENYL)CYTOSINE; NUCLEOSIDE DERIVATIVE; PYRIMIDINONE DERIVATIVE; UNINDEXED DRUG;

AMINATION; ARTICLE; DRUG SYNTHESIS; HEATING; MICROWAVE IRRADIATION; SILYLATION;

EID: 47349122417     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1067094     Document Type: Article

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