A comparison of chitosan-silica and sodium starch glycolate as disintegrants for spheronized extruded microcrystalline cellulose pellets

Drug Development and Industrial Pharmacy

Volumn 37, Issue 7, 2011, Pages 825-831

  Goyanes, Alvaro ^a   Souto, Consuelo ^a   Martínez Pacheco, Ramón ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Chitosan silica; disintegrant; drug release; MCC; pellet; sodium starch glycolate

Indexed keywords

AEROSIL; CHITOSAN; DISINTEGRATING AGENT; HYDROCHLOROTHIAZIDE; MICROCRYSTALLINE CELLULOSE; SORBITOL; STARCH GLYCOLATE SODIUM;

ARTICLE; CHEMICAL COMPOSITION; DRUG FORMULATION; DRUG PELLET; DRUG POTENTIATION; DRUG RELEASE; PELLET EXTRUSION; PHYSICAL CHEMISTRY; SPHERONIZATION; TABLET;

CELLULOSE; CHITOSAN; DOSAGE FORMS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; EXCIPIENTS; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; POROSITY; SILICON DIOXIDE; SOLUBILITY; STARCH;

EID: 79958757097     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2010.545415     Document Type: Article

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