Control of drug release by incorporation of sorbitol or mannitol in microcrystalline-cellulose-based pellets prepared by extrusion-spheronization

Pharmaceutical Development and Technology

Volumn 15, Issue 6, 2010, Pages 626-635

  Goyanes, Alvaro ^a   Souto, Consuelo ^a   Martínez Pacheco, Ramón ^a  

^a Universidade de Santiago de Compostela   (Spain)

Author keywords

Extrusion spheronization; Mannitol; Microcrystalline cellulose; Pellet; Sorbitol

Indexed keywords

HYDROCHLOROTHIAZIDE; MANNITOL; MICROCRYSTALLINE CELLULOSE; POLYOL; SORBITOL;

ARTICLE; DRUG FORMULATION; DRUG PELLET; DRUG RELEASE; DRUG SOLUBILITY; PELLET EXTRUSION; POROSITY; PRIORITY JOURNAL; SPHERONIZATION;

CELLULOSE; DELAYED-ACTION PREPARATIONS; EXCIPIENTS; HYDROCHLOROTHIAZIDE; MANNITOL; SOLUBILITY; SORBITOL; WATER;

EID: 78149256878     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450903419653     Document Type: Article

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