Caspase cleavage of the Golgi stacking factor GRASP65 is required for Fas/CD95-mediated apoptosis

Cell Death and Disease

Volumn 1, Issue 10, 2010, Pages

  Cheng, J P X ^a   Betin, V M S ^a   Weir, H ^a   Shelmani, G M A ^a   Moss, D K ^a,b   Lane, J D ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Apoptosis; Fas CD95; Golgi apparatus; GRASP65

Indexed keywords

CASPASE; FAS LIGAND; GOLGI REASSEMBLY AND STACKING PROTEIN; PROTEIN; PROTEIN BCL X; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; FAS ANTIGEN; GORASP1 PROTEIN, HUMAN; MEMBRANE PROTEIN; THAPSIGARGIN;

APOPTOSIS; ARTICLE; BASE PAIRING; CARBOXY TERMINAL SEQUENCE; CELL PROTECTION; GENE EXPRESSION; GENE SILENCING; GOLGI COMPLEX; HUMAN; HUMAN CELL; HYDROPHOBICITY; MITOCHONDRION; MOLECULAR INTERACTION; MUTAGENESIS; PDZ DOMAIN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; AMINO ACID SEQUENCE; CHEMISTRY; GENETICS; HELA CELL; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN TERTIARY STRUCTURE; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANTIGENS, CD95; APOPTOSIS; BCL-X PROTEIN; CASPASES; FAS LIGAND PROTEIN; GOLGI APPARATUS; HELA CELLS; HUMANS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; THAPSIGARGIN;

EID: 79958701128     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2010.59     Document Type: Article

References (40)

1. Bonifacino JS, Glick BS. The mechanisms of vesicle budding and fusion. Cell 2004; 116: 153-166. (Pubitemid 38167309)
2. Betin VMS, Lane JD. The cytoskeleton and the control of organelle dynamics in the apoptotic execution phase. SEB Symp Series 2007; 59: 267-289.
3. Ferri KF, Kroemer G. Organelle-specific initiation of cell death pathways. Nat Cell Biol 2001; 3: E255-E263.
4. Hicks SW, Machamer CE. Golgi structure in stress sensing and apoptosis. Biochim Biophys Acta 2005; 1744: 406-414. (Pubitemid 40848258)
5. Maag RS, Hicks SW, Machamer CE. Death from within: apoptosis and the secretory pathway. Curr Opin Cell Biol 2003; 15: 456-461. (Pubitemid 36928048)
6. Lane JD, Allan VJ, Woodman PG. Active relocation of chromatin and endoplasmic reticulum into blebs in late apoptotic cells. J Cell Sci 2005; 118 (Part 17): 4059-4071. (Pubitemid 41410287)
7. Cosulich SC, Horiuchi H, Zerial M, Clarke PR, Woodman PG. Cleavage of rabaptin-5 blocks endosome fusion during apoptosis. EMBO J 1997; 16: 6182-6191. (Pubitemid 27458338)
8. Lowe M, Lane JD, Woodman PG, Allan VJ. Caspase-mediated cleavage of syntaxin 5 and giantin accompanies inhibition of secretory traffic during apoptosis. J Cell Sci 2004; 117 (Part 7): 1139-1150. (Pubitemid 38456095)
9. Mancini M, Machamer CE, Roy S, Nicholson DW, Thornberry NA, Casciola-Rosen LA et al. Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis. J Cell Biol 2000; 149: 603-612. (Pubitemid 30252394)
10. Chiu R, Novikov L, Mukherjee S, Shields D. A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis. J Cell Biol 2002; 159: 637-648.
11. Lane JD, Lucocq J, Pryde J, Barr FA, Woodman PG, Allan VJ et al. Caspase-mediated cleavage of the stacking protein GRASP65 is required for Golgi fragmentation during apoptosis. J Cell Biol 2002; 156: 495-509. (Pubitemid 34839897)
12. Maag RS, Mancini M, Rosen A, Machamer CE. Caspase-resistant Golgin-160 disrupts apoptosis induced by secretory pathway stress and ligation of death receptors. Mol Biol Cell 2005; 16: 3019-3027. (Pubitemid 40741244)
13. Barr FA, Puype M, Vandekerckhove J, Warren G. GRASP65, a protein involved in the stacking of Golgi cisternae. Cell 1997; 91: 253-262. (Pubitemid 27456392)
14. Puthenveedu MA, Bachert C, Puri S, Lanni F, Linstedt AD. GM130 and GRASP65- dependent lateral cisternal fusion allows uniform Golgi-enzyme distribution. Nat Cell Biol 2006; 8: 238-248. (Pubitemid 43336065)
15. Barr FA, Preisinger C, Kopajtich R, Korner R. Golgi matrix proteins interact with p24 cargo receptors and aid their efficient retention in the Golgi apparatus. J Cell Biol 2001; 155: 885-891. (Pubitemid 34286240)
16. D'Angelo G, Prencipe L, Iodice L, Beznoussenko G, Savarese M, Marra P et al. GRASP65 and GRASP55 sequentially promote the transport of C-terminal valine bearing cargoes to and through the golgi complex. J Biol Chem 2009; 284: 34849-34860.
17. Kuo A, Zhong C, Lane WS, Derynck R. Transmembrane transforming growth factor-alpha tethers to the PDZ domain-containing, Golgi membrane-associated protein p59/GRASP55. Embo J 2000; 19: 6427-6439.
18. Yoshimura S, Yoshioka K, Barr FA, Lowe M, Nakayama K, Ohkuma S et al. Convergence of cell cycle regulation and growth factor signals on GRASP65. J Biol Chem 2005; 280: 23048-23056. (Pubitemid 40853215)
19. Bisel B, Wang Y, Wei JH, Xiang Y, Tang D, Miron-Mendoza M et al. ERK regulates Golgi and centrosome orientation towards the leading edge through GRASP65. J Cell Biol 2008; 182: 837-843.
20. Preisinger C, Korner R, Wind M, Lehmann WD, Kopajtich R, Barr FA. Plk1 docking to GRASP65 phosphorylated by Cdk1 suggests a mechanism for Golgi checkpoint signalling. EMBO J 2005; 24: 753-765. (Pubitemid 40396105)
21. Lin CY, Madsen ML, Yarm FR, Jang YJ, Liu X, Erikson RL. Peripheral Golgi protein GRASP65 is a target of mitotic polo-like kinase (Plk) and Cdc2. Proc Natl Acad Sci USA 2000; 97: 12589-12594.
22. Sutterlin C, Hsu P, Mallabiabarrena A, Malhotra V. Fragmentation and dispersal of the pericentriolar Golgi complex is required for entry into mitosis in mammalian cells. Cell 2002; 109: 359-369. (Pubitemid 34606878)
23. Sutterlin C, Polishchuk R, Pecot M, Malhotra V. The Golgi-associated protein GRASP65 regulates spindle dynamics and is essential for cell division. Mol Biol Cell 2005; 16: 3211-3222. (Pubitemid 40962593)
24. Wang Y, Seemann J, Pypaert M, Shorter J, Warren G. A direct role for GRASP65 as a mitotically regulated Golgi stacking factor. EMBO J 2003; 22: 3279-3290. (Pubitemid 36834858)
25. Lowe M, Barr FA. Inheritance and biogenesis of organelles in the secretory pathway. Nat Rev Mol Cell Biol 2007; 8: 429-439. (Pubitemid 46809151)
26. Walker A, Ward C, Sheldrake TA, Dransfield I, Rossi AG, Pryde JG et al. Golgi fragmentation during Fas-mediated apoptosis is associated with the rapid loss of GM130. Biochem Biophys Res Commun 2004; 316: 6-11. (Pubitemid 38299120)
27. Hicks SW, Machamer CE. The NH2-terminal domain of Golgin-160 contains both Golgi and nuclear targeting information. J Biol Chem 2002; 277: 35833-35839.
28. Sbodio JI, Hicks SW, Simon D, Machamer CE. GCP60 preferentially interacts with a caspase-generated Golgin-160 fragment. J Biol Chem 2006; 281: 27924-27931. (Pubitemid 44414504)
29. Wang Y, Satoh A, Warren G. Mapping the functional domains of the Golgi stacking factor GRASP65. J Biol Chem 2005; 280: 4921-4928. (Pubitemid 40288667)
30. Keppler OT, Peter ME, Hinderlich S, Moldenhauer G, Stehling P, Schmitz I et al. Differential sialylation of cell surface glycoconjugates in a human B lymphoma cell line regulates susceptibility for CD95 (APO-1/Fas)-mediated apoptosis and for infection by a lymphotropic virus. Glycobiology 1999; 9: 557-569. (Pubitemid 29250922)
31. Xiang Y, Wang Y. GRASP55 and GRASP65 play complementary and essential roles in Golgi cisternal stacking. J Cell Biol 2010; 188: 237-251.
32. Itoh N, Nagata S. A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen. J Biol Chem 1993; 268: 10932-10937. (Pubitemid 23162276)
33. Ivanov VN, Lopez Bergami P, Maulit G, Sato TA, Sassoon D, Ronai Z. FAP-1 association with Fas (Apo-1) inhibits Fas expression on the cell surface. Mol Cell Biol 2003; 23: 3623-3635. (Pubitemid 36539194)
34. Bennett M, Macdonald K, Chan SW, Luzio JP, Simari R, Weissberg P. Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis. Science 1998; 282: 290-293. (Pubitemid 28487200)
35. Wang X, Zhang J, Kim HP, Wang Y, Choi AM, Ryter SW. Bcl-XL disrupts death-inducing signal complex formation in plasma membrane induced by hypoxia/reoxygenation. Faseb J 2004; 18: 1826-1833. (Pubitemid 39602269)
36. Trinkle-Mulcahy L, Boulon S, Lam YW, Urcia R, Boisvert FM, Vandermoere F et al. Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes. J Cell Biol 2008; 183: 223-239.
37. Moss DK, Betin VM, Malesinski SD, Lane JD. A novel role for microtubules in apoptotic chromatin dynamics and cellular fragmentation. J Cell Sci 2006; 119 (Part 11): 2362-2374. (Pubitemid 43960325)
38. Moss DK, Wilde A, Lane JD. Dynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase. J Cell Sci 2009; 122: 656-666.
39. Goldstein JC, Waterhouse NJ, Juin P, Evan GI, Green DR. The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat Cell Biol 2000; 2: 156-162.
40. Marra P, Maffucci T, Daniele T, Tullio GD, Ikehara Y, Chan EK et al. The GM130 and GRASP65 Golgi proteins cycle through and define a subdomain of the intermediate compartment. Nat Cell Biol 2001; 3: 1101-1113. (Pubitemid 33130461)