메뉴 건너뛰기




Volumn 15, Issue 7, 2011, Pages 889-897

NK-1 as a melanoma target

Author keywords

apoptosis; metastasis; mitogenesis; neoangiogenesis; NK 1 receptor antagonist; substance P

Indexed keywords

3 [3,5 BIS(TRIFLUOROMETHYL)BENZYLOXY] 2 PHENYLPIPERIDINE; ANTINEOPLASTIC AGENT; APREPITANT; CYCLOPHOSPHAMIDE; CYTOSTATIC AGENT; G PROTEIN COUPLED RECEPTOR; HISTAMINE; N ACETYLTRYPTOPHAN 3,5 BIS(TRIFLUOROMETHYL)BENZYL ESTER; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; SUBSTANCE P; UNCLASSIFIED DRUG; VINBLASTINE;

EID: 79958293719     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.2011.586633     Document Type: Review
Times cited : (15)

References (37)
  • 2
    • 79953669021 scopus 로고    scopus 로고
    • The NK-1 receptor: A new target in cancer therapy
    • Munoz M, Rosso M, Covenas R. The NK-1 receptor: a new target in cancer therapy. Curr Drug Targets 2011;12:909-21
    • (2011) Curr Drug Targets , vol.12 , pp. 909-21
    • Munoz, M.1    Rosso, M.2    Covenas, R.3
  • 3
    • 33747199597 scopus 로고    scopus 로고
    • Tachykinins and their receptors in human malignancies
    • DOI 10.2174/138945006778019282
    • Palma C. Tachykinins and their receptors in human malignancies. Curr Drug Targets 2006;7:1043-52 (Pubitemid 44227587)
    • (2006) Current Drug Targets , vol.7 , Issue.8 , pp. 1043-1052
    • Palma, C.1
  • 4
    • 77955151651 scopus 로고    scopus 로고
    • The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1 receptor antagonist aprepitant on melanoma cell lines
    • Munoz M, Rosso M, Robles-Frias MJ, et al. The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1 receptor antagonist aprepitant on melanoma cell lines. Lab Invest 2010;90:1259-69
    • (2010) Lab Invest , vol.90 , pp. 1259-69
    • Munoz, M.1    Rosso, M.2    Robles-Frias, M.J.3
  • 5
    • 3042799978 scopus 로고    scopus 로고
    • Antitumoral action of the neurokinin-1 receptor antagonist L-733 060 on human melanoma cell lines
    • DOI 10.1097/01.cmr.0000129376.22141.a3
    • Munoz M, Perez A, Rosso M, et al. Antitumoral action of the neurokinin-1 receptor antagonist L-733,060 on human melanoma cell lines. Melanoma Res 2004;14:183-8 (Pubitemid 38879579)
    • (2004) Melanoma Research , vol.14 , Issue.3 , pp. 183-188
    • Munoz, M.1    Perez, A.2    Rosso, M.3    Zamarriego, C.4    Rosso, R.5
  • 7
    • 33745590666 scopus 로고    scopus 로고
    • The NK-1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on human pancreatic cancer cell lines
    • DOI 10.2174/157018006777574168
    • Munoz M, Rosso M, Covenas R. The NK-1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on human pancreatic cancer cell lines. Lett Drug Des Discov 2006;3:323-9 (Pubitemid 43988115)
    • (2006) Letters in Drug Design and Discovery , vol.3 , Issue.5 , pp. 323-329
    • Munoz, M.1    Rosso, M.2    Covenas, R.3
  • 8
    • 40549118238 scopus 로고    scopus 로고
    • NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human laryngeal cancer cell line HEp-2
    • Munoz M, Rosso M, Aguilar FJ, et al. NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human laryngeal cancer cell line HEp-2. Invest New Drugs 2008;26:111-18
    • (2008) Invest New Drugs , vol.26 , pp. 111-18
    • Munoz, M.1    Rosso, M.2    Aguilar, F.J.3
  • 9
    • 51049102605 scopus 로고    scopus 로고
    • The NK-1 receptor is expressed in human primary gastric and colon adenocarcinomas and is involved in the antitumor action of L-733,060 and the mitogenic action of substance P on human gastrointestinal cancer cell lines
    • Rosso M, Robles-Frias MJ, Covenas R, et al. The NK-1 receptor is expressed in human primary gastric and colon adenocarcinomas and is involved in the antitumor action of L-733,060 and the mitogenic action of substance P on human gastrointestinal cancer cell lines. Tumor Biol 2008;29:245-54
    • (2008) Tumor Biol , vol.29 , pp. 245-54
    • Rosso, M.1    Robles-Frias, M.J.2    Covenas, R.3
  • 10
    • 77952240278 scopus 로고    scopus 로고
    • The NK-1 receptor antagonist aprepitant as a broad spectrum antitumor drug
    • Munoz M, Rosso M. The NK-1 receptor antagonist aprepitant as a broad spectrum antitumor drug. Invest New Drugs 2010;28:187-93
    • (2010) Invest New Drugs , vol.28 , pp. 187-93
    • Munoz, M.1    Rosso, M.2
  • 11
    • 79952267748 scopus 로고    scopus 로고
    • The NK-1 receptor antagonist L- 732,138 induces apoptosis and counteracts substance P-related mitogenesis in human melanoma cell lines
    • Munoz M, Rosso M, Gonzalez-Ortega A, et al. The NK-1 receptor antagonist L- 732,138 induces apoptosis and counteracts substance P-related mitogenesis in human melanoma cell lines. Cancers 2010;2:611-23
    • (2010) Cancers , vol.2 , pp. 611-23
    • Munoz, M.1    Rosso, M.2    Gonzalez-Ortega, A.3
  • 12
    • 33646558897 scopus 로고    scopus 로고
    • A role for substance P in cancer promotion and progression: A mechanism to counteract intracellular death signals following oncogene activation or DNA damage
    • DOI 10.1007/s10555-006-8161-9, Metalloproteinases and Cancer
    • Esteban F, Munoz M, Gonzalez-Moles MA, et al. A role for substance P in cancer promotion and progression: a mechanism to counteract intracellular death signals following oncogene activation or DNA damage. Cancer Metast Rev 2006;25:137-45 (Pubitemid 43723988)
    • (2006) Cancer and Metastasis Reviews , vol.25 , Issue.1 , pp. 137-145
    • Esteban, F.1    Munoz, M.2    Gonzalez-Moles, M.A.3    Rosso, M.4
  • 15
    • 79958292909 scopus 로고    scopus 로고
    • The NK-1 receptor is expressed in human leukemia and is involved in the antitumor action of aprepitant and other NK- 1 receptor antagonists on acute lymphoblastic leukemia cell lines
    • In press
    • Munoz M, Gonzalez-Ortega A, Covenas R. The NK-1 receptor is expressed in human leukemia and is involved in the antitumor action of aprepitant and other NK- 1 receptor antagonists on acute lymphoblastic leukemia cell lines. Invest New Drugs 2011;In press
    • (2011) Invest New Drugs
    • Munoz, M.1    Gonzalez-Ortega, A.2    Covenas, R.3
  • 16
    • 77950639335 scopus 로고    scopus 로고
    • A new frontier in the treatment of cancer: NK-1 receptor antagonists
    • Munoz M, Rosso M, Covenas R. A new frontier in the treatment of cancer: NK-1 receptor antagonists. Curr Med Chem 2010;17:504-16
    • (2010) Curr Med Chem , vol.17 , pp. 504-16
    • Munoz, M.1    Rosso, M.2    Covenas, R.3
  • 17
    • 0028291775 scopus 로고
    • Characterization of the SP receptor-mediated Ca influx in cDNA transfected CHO cells
    • Mochizuki-Oda N, Nakajima Y, Nakanishi S, et al. Characterization of the SP receptor-mediated Ca influx in cDNA transfected CHO cells. J Biol Chem 1994;269:9651-8
    • (1994) J Biol Chem , vol.269 , pp. 9651-8
    • Mochizuki-Oda, N.1    Nakajima, Y.2    Nakanishi, S.3
  • 18
    • 0027961056 scopus 로고
    • Multiple mechanisms of arachidonic acid release in Chinese hamster ovary cells transfected with cDNA of substance P receptor
    • DOI 10.1016/0006-2952(94)90459-6
    • Garcia M, Sakamoto K, Shigekawa M, et al. Multiple mechanisms of arachidonic acid release in Chinese hamster ovary cells transfected with cDNA of SP receptor. Biochem Pharmacol 1994;48:1735-41 (Pubitemid 24338999)
    • (1994) Biochemical Pharmacology , vol.48 , Issue.9 , pp. 1735-1741
    • Garcia, M.1    Sakamoto, K.2    Shigekawa, M.3    Nakanishi, S.4    Ito, S.5
  • 19
    • 0027318274 scopus 로고
    • Thapsigargin blocks the mobilisation of intracellular calcium caused by activation of human NK1 (long) receptors expressed in Chinese hamster ovary cells
    • Seabrook GR, Fong TM. Thapsigargin blocks the mobilization of intracellular Ca caused by activation of human NK1 (long) receptors expressed in CHO cells. Neurosci Lett 1993;152:9-12 (Pubitemid 23149300)
    • (1993) Neuroscience Letters , vol.152 , Issue.1-2 , pp. 9-12
    • Seabrook, G.R.1    Fong, T.M.2
  • 20
    • 0026683453 scopus 로고
    • Ligand binding kinetics of substance P and neurokinin A receptors stably expressed in CHO cells and evidence for differential stimulation of inositol 1, 4, 5-triphosphate and camp second messenger responses
    • Takeda Y, Blount P, Sachais BS, et al. Ligand binding kinetics of substance P and neurokinin A receptors stably expressed in CHO cells and evidence for differential stimulation of inositol 1, 4, 5-triphosphate and camp second messenger responses. J Neurochem 1992;59:740-5
    • (1992) J Neurochem , vol.59 , pp. 740-5
    • Takeda, Y.1    Blount, P.2    Sachais, B.S.3
  • 21
    • 0026795882 scopus 로고
    • Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cAMP cascades in transfected Chinese hamster ovary cells
    • Nakajima Y, Tsuchida K, Negishi M, et al. Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cAMP cascades in transfected Chinese hamster ovary cells. J Biol Chem 1992;267:2437-42
    • (1992) J Biol Chem , vol.267 , pp. 2437-42
    • Nakajima, Y.1    Tsuchida, K.2    Negishi, M.3
  • 22
    • 0026752764 scopus 로고
    • Multiple intracellular signalling pathways of the neuropeptide SP receptor
    • Mitsuhashi M, Ohashi Y, Schichijo S, et al. Multiple intracellular signalling pathways of the neuropeptide SP receptor. J Neurosci Res 1992;32:437-43
    • (1992) J Neurosci Res , vol.32 , pp. 437-43
    • Mitsuhashi, M.1    Ohashi, Y.2    Schichijo, S.3
  • 24
    • 23044450652 scopus 로고    scopus 로고
    • The NK1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on neuroblastoma and glioma cell lines
    • DOI 10.1016/j.npep.2005.03.004, PII S014341790500034X
    • Munoz M, Rosso M, Perez A, et al. The NK1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on neuroblastoma and glioma cell lines. Neuropeptides 2005;39:427-32 (Pubitemid 41073623)
    • (2005) Neuropeptides , vol.39 , Issue.4 , pp. 427-432
    • Munoz, M.1    Rosso, M.2    Perez, A.3    Covenas, R.4    Rosso, R.5    Zamarriego, C.6    Piruat, J.I.7
  • 25
    • 0029961467 scopus 로고    scopus 로고
    • Substance P-induced mitogenesis in human astrocytoma cells correlates with activation of the mitogen-activated protein kinase signaling pathway
    • Luo W, Sharif TR, Sharif M. Substance P-induced mitogenesis in human astrocytoma cells correlates with activation of the mitogen-activated protein kinase signaling pathway. Cancer Res 1996;56:4983-91 (Pubitemid 26374439)
    • (1996) Cancer Research , vol.56 , Issue.21 , pp. 4983-4991
    • Luo, W.1    Sharif, T.R.2    Sharif, M.3
  • 26
    • 27644463170 scopus 로고    scopus 로고
    • Role of NK-1 and NK-2 tachykinin receptor antagonism on the growth of human breast carcinoma cell line MDA-MB-231
    • DOI 10.1097/00001813-200511000-00007
    • Bigioni M, Benzo A, Irrissuto C, et al. Role of NK-1 and NK-2 tachykinin receptor antagonism on the growth of human breast carcinoma cell line MDA-MB-231. Anticancer Drugs 2005;16:1083-9 (Pubitemid 41565774)
    • (2005) Anti-Cancer Drugs , vol.16 , Issue.10 , pp. 1083-1089
    • Bigioni, M.1    Benzo, A.2    Irrissuto, C.3    Maggi, C.A.4    Goso, C.5
  • 28
    • 16444381759 scopus 로고    scopus 로고
    • Overexpression of soluble TRAIL induces apoptosis in human lung adenocarcinoma and inhibits growth of tumor xenografts in nude mice
    • DOI 10.1158/0008-5472.CAN-04-2749
    • Shi J, Zheng D, Liu Y, et al. Over-expression of soluble TRAIL induces apoptosis in human lung adenocarcinoma and inhibits growth of tumor xenografts in nude mice. Cancer Res 2005;65:1687-92 (Pubitemid 40478593)
    • (2005) Cancer Research , vol.65 , Issue.5 , pp. 1687-1692
    • Shi, J.1    Zheng, D.2    Liu, Y.3    Mai, H.S.4    Tam, P.5    Farzaneh, F.6    Xu, R.7
  • 29
    • 77749298960 scopus 로고    scopus 로고
    • Efficacy of aprepitant in patients receiving high-dose chemotherapy with hematopoietic stem cell support
    • Paul B, Trovato JA, Thompson J, et al. Efficacy of aprepitant in patients receiving high-dose chemotherapy with hematopoietic stem cell support. J Oncol Pharm Pract 2010;16:45-51
    • (2010) J Oncol Pharm Pract , vol.16 , pp. 45-51
    • Paul, B.1    Trovato, J.A.2    Thompson, J.3
  • 30
    • 77958174965 scopus 로고    scopus 로고
    • Aprepitant use in children, adolescents, and young adults for the control of chemotherapy-induced nausea and vomiting (CINV)
    • Choi MR, Jiles C, Seibel NL. Aprepitant use in children, adolescents, and young adults for the control of chemotherapy-induced nausea and vomiting (CINV). J Pediatr Hematol Oncol 2010;32:e268-71
    • (2010) J Pediatr Hematol Oncol , vol.32
    • Choi, M.R.1    Jiles, C.2    Seibel, N.L.3
  • 31
    • 77956193969 scopus 로고    scopus 로고
    • Targeting the neurokinin receptor 1 with aprepitant: A novel antipruritic strategy
    • Stander S, Siepmann D, Herrgott I, et al. Targeting the neurokinin receptor 1 with aprepitant: a novel antipruritic strategy. PLoS One 2010;5:e10968
    • (2010) PLoS One , vol.5
    • Stander, S.1    Siepmann, D.2    Herrgott, I.3
  • 32
    • 71049145217 scopus 로고    scopus 로고
    • Randomized, double-blind, dose-ranging trial of the oral neurokinin-1 receptor antagonist casopitant mesylate for the prevention of cisplatin-induced nausea and vomiting
    • Roila F, Rolski J, Ramlau R, et al. Randomized, double-blind, dose-ranging trial of the oral neurokinin-1 receptor antagonist casopitant mesylate for the prevention of cisplatin-induced nausea and vomiting. Ann Oncol 2009;20:1867-73
    • (2009) Ann Oncol , vol.20 , pp. 1867-73
    • Roila, F.1    Rolski, J.2    Ramlau, R.3
  • 33
    • 45349096499 scopus 로고    scopus 로고
    • Cell motility through plasma membrane blebbing
    • DOI 10.1083/jcb.200802081
    • Fackler OT, Grosse R. Cell motility through plasma membrane blebbing. J Cell Biol 2008;181:879-84 (Pubitemid 351846821)
    • (2008) Journal of Cell Biology , vol.181 , Issue.6 , pp. 879-884
    • Fackler, O.T.1    Grosse, R.2
  • 34
    • 33749165919 scopus 로고    scopus 로고
    • Can anesthetic technique for primary breast cancer surgery affect recurrence or metastasis?
    • DOI 10.1097/00000542-200610000-00008, PII 0000054220061000000008
    • Exadaktylos AK, Buggy DJ, Moriarty DC, et al. Can anesthetics technique for primary breast cancer surgery affect recurrence of metastases? Anesthesiology 2006;105:660-4 (Pubitemid 44477309)
    • (2006) Anesthesiology , vol.105 , Issue.4 , pp. 660-664
    • Exadaktylos, A.K.1    Buggy, D.J.2    Moriarty, D.C.3    Mascha, E.4    Sessler, D.I.5
  • 35
    • 77955653145 scopus 로고    scopus 로고
    • Paravertebral anesthesia: How substance P and the NK-1 receptor could be involved in regional block and breast cancer recurrence
    • Munoz M, Rosso M, Casinello F, et al. Paravertebral anesthesia: how substance P and the NK-1 receptor could be involved in regional block and breast cancer recurrence. Breast Cancer Res Treat 2010;122:601-3
    • (2010) Breast Cancer Res Treat , vol.122 , pp. 601-3
    • Munoz, M.1    Rosso, M.2    Casinello, F.3
  • 36
    • 79955611266 scopus 로고    scopus 로고
    • Synergy between microtubule-destabilizing agents and neurokinin 1 receptor antagonists identified by an siRNA synthetic lethal screen
    • Kitchens CA, McDonald PR, Pollack IF, et al. Synergy between microtubule-destabilizing agents and neurokinin 1 receptor antagonists identified by an siRNA synthetic lethal screen. FASEB J 2009;23:756.13
    • (2009) FASEB J , vol.23 , pp. 756-813
    • Kitchens, C.A.1    McDonald, P.R.2    Pollack, I.F.3
  • 37
    • 79955621751 scopus 로고    scopus 로고
    • Efectos de los antagonistas de los receptores NK1 y de la dexametasona sobre la inflamacion neurogenica inducida por ciclofosfamida y por radiacion X en la rata
    • Alfieri AB, Cubeddu LX. Efectos de los antagonistas de los receptores NK1 y de la dexametasona sobre la inflamacion neurogenica inducida por ciclofosfamida y por radiacion X, en la rata. AVFT 2004;23:61-6
    • (2004) AVFT , vol.23 , pp. 61-6
    • Alfieri, A.B.1    Cubeddu, L.X.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.