-
2
-
-
79953669021
-
The NK-1 receptor: A new target in cancer therapy
-
Munoz M, Rosso M, Covenas R. The NK-1 receptor: a new target in cancer therapy. Curr Drug Targets 2011;12:909-21
-
(2011)
Curr Drug Targets
, vol.12
, pp. 909-21
-
-
Munoz, M.1
Rosso, M.2
Covenas, R.3
-
3
-
-
33747199597
-
Tachykinins and their receptors in human malignancies
-
DOI 10.2174/138945006778019282
-
Palma C. Tachykinins and their receptors in human malignancies. Curr Drug Targets 2006;7:1043-52 (Pubitemid 44227587)
-
(2006)
Current Drug Targets
, vol.7
, Issue.8
, pp. 1043-1052
-
-
Palma, C.1
-
4
-
-
77955151651
-
The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1 receptor antagonist aprepitant on melanoma cell lines
-
Munoz M, Rosso M, Robles-Frias MJ, et al. The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1 receptor antagonist aprepitant on melanoma cell lines. Lab Invest 2010;90:1259-69
-
(2010)
Lab Invest
, vol.90
, pp. 1259-69
-
-
Munoz, M.1
Rosso, M.2
Robles-Frias, M.J.3
-
5
-
-
3042799978
-
Antitumoral action of the neurokinin-1 receptor antagonist L-733 060 on human melanoma cell lines
-
DOI 10.1097/01.cmr.0000129376.22141.a3
-
Munoz M, Perez A, Rosso M, et al. Antitumoral action of the neurokinin-1 receptor antagonist L-733,060 on human melanoma cell lines. Melanoma Res 2004;14:183-8 (Pubitemid 38879579)
-
(2004)
Melanoma Research
, vol.14
, Issue.3
, pp. 183-188
-
-
Munoz, M.1
Perez, A.2
Rosso, M.3
Zamarriego, C.4
Rosso, R.5
-
6
-
-
4544321026
-
Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs
-
DOI 10.1002/ijc.20410
-
Lang K, Drell TL, Lindecke A, et al. Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs. Int J Cancer 2004;112:231-8 (Pubitemid 39244363)
-
(2004)
International Journal of Cancer
, vol.112
, Issue.2
, pp. 231-238
-
-
Lang, K.1
Drell IV, T.L.2
Lindecke, A.3
Niggemann, B.4
Kaltschmidt, C.5
Zaenker, K.S.6
Entschladen, F.7
-
7
-
-
33745590666
-
The NK-1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on human pancreatic cancer cell lines
-
DOI 10.2174/157018006777574168
-
Munoz M, Rosso M, Covenas R. The NK-1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on human pancreatic cancer cell lines. Lett Drug Des Discov 2006;3:323-9 (Pubitemid 43988115)
-
(2006)
Letters in Drug Design and Discovery
, vol.3
, Issue.5
, pp. 323-329
-
-
Munoz, M.1
Rosso, M.2
Covenas, R.3
-
8
-
-
40549118238
-
NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human laryngeal cancer cell line HEp-2
-
Munoz M, Rosso M, Aguilar FJ, et al. NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human laryngeal cancer cell line HEp-2. Invest New Drugs 2008;26:111-18
-
(2008)
Invest New Drugs
, vol.26
, pp. 111-18
-
-
Munoz, M.1
Rosso, M.2
Aguilar, F.J.3
-
9
-
-
51049102605
-
The NK-1 receptor is expressed in human primary gastric and colon adenocarcinomas and is involved in the antitumor action of L-733,060 and the mitogenic action of substance P on human gastrointestinal cancer cell lines
-
Rosso M, Robles-Frias MJ, Covenas R, et al. The NK-1 receptor is expressed in human primary gastric and colon adenocarcinomas and is involved in the antitumor action of L-733,060 and the mitogenic action of substance P on human gastrointestinal cancer cell lines. Tumor Biol 2008;29:245-54
-
(2008)
Tumor Biol
, vol.29
, pp. 245-54
-
-
Rosso, M.1
Robles-Frias, M.J.2
Covenas, R.3
-
10
-
-
77952240278
-
The NK-1 receptor antagonist aprepitant as a broad spectrum antitumor drug
-
Munoz M, Rosso M. The NK-1 receptor antagonist aprepitant as a broad spectrum antitumor drug. Invest New Drugs 2010;28:187-93
-
(2010)
Invest New Drugs
, vol.28
, pp. 187-93
-
-
Munoz, M.1
Rosso, M.2
-
11
-
-
79952267748
-
The NK-1 receptor antagonist L- 732,138 induces apoptosis and counteracts substance P-related mitogenesis in human melanoma cell lines
-
Munoz M, Rosso M, Gonzalez-Ortega A, et al. The NK-1 receptor antagonist L- 732,138 induces apoptosis and counteracts substance P-related mitogenesis in human melanoma cell lines. Cancers 2010;2:611-23
-
(2010)
Cancers
, vol.2
, pp. 611-23
-
-
Munoz, M.1
Rosso, M.2
Gonzalez-Ortega, A.3
-
12
-
-
33646558897
-
A role for substance P in cancer promotion and progression: A mechanism to counteract intracellular death signals following oncogene activation or DNA damage
-
DOI 10.1007/s10555-006-8161-9, Metalloproteinases and Cancer
-
Esteban F, Munoz M, Gonzalez-Moles MA, et al. A role for substance P in cancer promotion and progression: a mechanism to counteract intracellular death signals following oncogene activation or DNA damage. Cancer Metast Rev 2006;25:137-45 (Pubitemid 43723988)
-
(2006)
Cancer and Metastasis Reviews
, vol.25
, Issue.1
, pp. 137-145
-
-
Esteban, F.1
Munoz, M.2
Gonzalez-Moles, M.A.3
Rosso, M.4
-
13
-
-
23244463917
-
Antitumoral action of the neurokinin-1-receptor antagonist L-733,060 and mitogenic action of substance P on human retinoblastoma cell lines
-
DOI 10.1167/iovs.04-1530
-
Munoz M, Rosso M, Perez A, et al. Antitumoural action of the neurokinin-1- receptor antagonist L-733,060 and mitogenic action of substance P on human retinoblastoma cell lines. Invest Ophthalmol Vis Sci 2005;46:2567-70 (Pubitemid 43119507)
-
(2005)
Investigative Ophthalmology and Visual Science
, vol.46
, Issue.7
, pp. 2567-2570
-
-
Munoz, M.1
Rosso, M.2
Perez, A.3
Covenas, R.4
Rosso, R.5
Zamarriego, C.6
Soult, J.A.7
Montero, I.8
-
14
-
-
34347273792
-
Neurokinin-1 receptors located in human retinoblastoma cell lines: Antitumor action of its antagonist, L-732,138
-
DOI 10.1167/iovs.05-1591
-
Munoz M, Rosso M, Covenas R, et al. Neurokinin-1 receptors located in human retinoblastoma cell lines: antitumor action of its antagonist, L-732,138. Invest Ophthalmol Vis Sci 2007;48:2775-81 (Pubitemid 351261233)
-
(2007)
Investigative Ophthalmology and Visual Science
, vol.48
, Issue.6
, pp. 2775-2781
-
-
Munoz, M.1
Rosso, M.2
Covenas, R.3
Montero, I.4
Gonzalez-Moles, M.A.5
Robles, M.J.6
-
15
-
-
79958292909
-
The NK-1 receptor is expressed in human leukemia and is involved in the antitumor action of aprepitant and other NK- 1 receptor antagonists on acute lymphoblastic leukemia cell lines
-
In press
-
Munoz M, Gonzalez-Ortega A, Covenas R. The NK-1 receptor is expressed in human leukemia and is involved in the antitumor action of aprepitant and other NK- 1 receptor antagonists on acute lymphoblastic leukemia cell lines. Invest New Drugs 2011;In press
-
(2011)
Invest New Drugs
-
-
Munoz, M.1
Gonzalez-Ortega, A.2
Covenas, R.3
-
16
-
-
77950639335
-
A new frontier in the treatment of cancer: NK-1 receptor antagonists
-
Munoz M, Rosso M, Covenas R. A new frontier in the treatment of cancer: NK-1 receptor antagonists. Curr Med Chem 2010;17:504-16
-
(2010)
Curr Med Chem
, vol.17
, pp. 504-16
-
-
Munoz, M.1
Rosso, M.2
Covenas, R.3
-
17
-
-
0028291775
-
Characterization of the SP receptor-mediated Ca influx in cDNA transfected CHO cells
-
Mochizuki-Oda N, Nakajima Y, Nakanishi S, et al. Characterization of the SP receptor-mediated Ca influx in cDNA transfected CHO cells. J Biol Chem 1994;269:9651-8
-
(1994)
J Biol Chem
, vol.269
, pp. 9651-8
-
-
Mochizuki-Oda, N.1
Nakajima, Y.2
Nakanishi, S.3
-
18
-
-
0027961056
-
Multiple mechanisms of arachidonic acid release in Chinese hamster ovary cells transfected with cDNA of substance P receptor
-
DOI 10.1016/0006-2952(94)90459-6
-
Garcia M, Sakamoto K, Shigekawa M, et al. Multiple mechanisms of arachidonic acid release in Chinese hamster ovary cells transfected with cDNA of SP receptor. Biochem Pharmacol 1994;48:1735-41 (Pubitemid 24338999)
-
(1994)
Biochemical Pharmacology
, vol.48
, Issue.9
, pp. 1735-1741
-
-
Garcia, M.1
Sakamoto, K.2
Shigekawa, M.3
Nakanishi, S.4
Ito, S.5
-
19
-
-
0027318274
-
Thapsigargin blocks the mobilisation of intracellular calcium caused by activation of human NK1 (long) receptors expressed in Chinese hamster ovary cells
-
Seabrook GR, Fong TM. Thapsigargin blocks the mobilization of intracellular Ca caused by activation of human NK1 (long) receptors expressed in CHO cells. Neurosci Lett 1993;152:9-12 (Pubitemid 23149300)
-
(1993)
Neuroscience Letters
, vol.152
, Issue.1-2
, pp. 9-12
-
-
Seabrook, G.R.1
Fong, T.M.2
-
20
-
-
0026683453
-
Ligand binding kinetics of substance P and neurokinin A receptors stably expressed in CHO cells and evidence for differential stimulation of inositol 1, 4, 5-triphosphate and camp second messenger responses
-
Takeda Y, Blount P, Sachais BS, et al. Ligand binding kinetics of substance P and neurokinin A receptors stably expressed in CHO cells and evidence for differential stimulation of inositol 1, 4, 5-triphosphate and camp second messenger responses. J Neurochem 1992;59:740-5
-
(1992)
J Neurochem
, vol.59
, pp. 740-5
-
-
Takeda, Y.1
Blount, P.2
Sachais, B.S.3
-
21
-
-
0026795882
-
Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cAMP cascades in transfected Chinese hamster ovary cells
-
Nakajima Y, Tsuchida K, Negishi M, et al. Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cAMP cascades in transfected Chinese hamster ovary cells. J Biol Chem 1992;267:2437-42
-
(1992)
J Biol Chem
, vol.267
, pp. 2437-42
-
-
Nakajima, Y.1
Tsuchida, K.2
Negishi, M.3
-
22
-
-
0026752764
-
Multiple intracellular signalling pathways of the neuropeptide SP receptor
-
Mitsuhashi M, Ohashi Y, Schichijo S, et al. Multiple intracellular signalling pathways of the neuropeptide SP receptor. J Neurosci Res 1992;32:437-43
-
(1992)
J Neurosci Res
, vol.32
, pp. 437-43
-
-
Mitsuhashi, M.1
Ohashi, Y.2
Schichijo, S.3
-
23
-
-
2542435999
-
Antitumoural action of L-733,060 on neuroblastoma and glioma cell lines
-
Munoz M, Perez A, Covenas R, et al. Antitumoural action of L-733,060 on neuroblastoma and glioma cell lines. Arch Ital Biol 2004;142:105-12 (Pubitemid 38691234)
-
(2004)
Archives Italiennes de Biologie
, vol.142
, Issue.2
, pp. 105-112
-
-
Munoz, M.1
Perez, A.2
Covenas, R.3
Rosso, M.4
Castro, E.5
-
24
-
-
23044450652
-
The NK1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on neuroblastoma and glioma cell lines
-
DOI 10.1016/j.npep.2005.03.004, PII S014341790500034X
-
Munoz M, Rosso M, Perez A, et al. The NK1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on neuroblastoma and glioma cell lines. Neuropeptides 2005;39:427-32 (Pubitemid 41073623)
-
(2005)
Neuropeptides
, vol.39
, Issue.4
, pp. 427-432
-
-
Munoz, M.1
Rosso, M.2
Perez, A.3
Covenas, R.4
Rosso, R.5
Zamarriego, C.6
Piruat, J.I.7
-
25
-
-
0029961467
-
Substance P-induced mitogenesis in human astrocytoma cells correlates with activation of the mitogen-activated protein kinase signaling pathway
-
Luo W, Sharif TR, Sharif M. Substance P-induced mitogenesis in human astrocytoma cells correlates with activation of the mitogen-activated protein kinase signaling pathway. Cancer Res 1996;56:4983-91 (Pubitemid 26374439)
-
(1996)
Cancer Research
, vol.56
, Issue.21
, pp. 4983-4991
-
-
Luo, W.1
Sharif, T.R.2
Sharif, M.3
-
26
-
-
27644463170
-
Role of NK-1 and NK-2 tachykinin receptor antagonism on the growth of human breast carcinoma cell line MDA-MB-231
-
DOI 10.1097/00001813-200511000-00007
-
Bigioni M, Benzo A, Irrissuto C, et al. Role of NK-1 and NK-2 tachykinin receptor antagonism on the growth of human breast carcinoma cell line MDA-MB-231. Anticancer Drugs 2005;16:1083-9 (Pubitemid 41565774)
-
(2005)
Anti-Cancer Drugs
, vol.16
, Issue.10
, pp. 1083-1089
-
-
Bigioni, M.1
Benzo, A.2
Irrissuto, C.3
Maggi, C.A.4
Goso, C.5
-
27
-
-
16844365620
-
11]SP: A dual inhibitor of growth and angiogenesis in pancreatic cancer
-
DOI 10.1158/0008-5472.CAN-04-3197
-
Guha S, Eibl G, Kisfalvi K, et al. Broad-spectrum G protein-coupled receptor antagonist, [D-Arg1,DTrp5,7,9, Leu11]SP: a dual inhibitor of growth and angiogenesis in pancreatic cancer. Cancer Res 2005;65:2738-45 (Pubitemid 40490075)
-
(2005)
Cancer Research
, vol.65
, Issue.7
, pp. 2738-2745
-
-
Guha, S.1
Eibl, G.2
Kisfalvi, K.3
Fan, R.S.4
Burdick, M.5
Reber, H.6
Hines, O.J.7
Strieter, R.8
Rozengurt, E.9
-
28
-
-
16444381759
-
Overexpression of soluble TRAIL induces apoptosis in human lung adenocarcinoma and inhibits growth of tumor xenografts in nude mice
-
DOI 10.1158/0008-5472.CAN-04-2749
-
Shi J, Zheng D, Liu Y, et al. Over-expression of soluble TRAIL induces apoptosis in human lung adenocarcinoma and inhibits growth of tumor xenografts in nude mice. Cancer Res 2005;65:1687-92 (Pubitemid 40478593)
-
(2005)
Cancer Research
, vol.65
, Issue.5
, pp. 1687-1692
-
-
Shi, J.1
Zheng, D.2
Liu, Y.3
Mai, H.S.4
Tam, P.5
Farzaneh, F.6
Xu, R.7
-
29
-
-
77749298960
-
Efficacy of aprepitant in patients receiving high-dose chemotherapy with hematopoietic stem cell support
-
Paul B, Trovato JA, Thompson J, et al. Efficacy of aprepitant in patients receiving high-dose chemotherapy with hematopoietic stem cell support. J Oncol Pharm Pract 2010;16:45-51
-
(2010)
J Oncol Pharm Pract
, vol.16
, pp. 45-51
-
-
Paul, B.1
Trovato, J.A.2
Thompson, J.3
-
30
-
-
77958174965
-
Aprepitant use in children, adolescents, and young adults for the control of chemotherapy-induced nausea and vomiting (CINV)
-
Choi MR, Jiles C, Seibel NL. Aprepitant use in children, adolescents, and young adults for the control of chemotherapy-induced nausea and vomiting (CINV). J Pediatr Hematol Oncol 2010;32:e268-71
-
(2010)
J Pediatr Hematol Oncol
, vol.32
-
-
Choi, M.R.1
Jiles, C.2
Seibel, N.L.3
-
31
-
-
77956193969
-
Targeting the neurokinin receptor 1 with aprepitant: A novel antipruritic strategy
-
Stander S, Siepmann D, Herrgott I, et al. Targeting the neurokinin receptor 1 with aprepitant: a novel antipruritic strategy. PLoS One 2010;5:e10968
-
(2010)
PLoS One
, vol.5
-
-
Stander, S.1
Siepmann, D.2
Herrgott, I.3
-
32
-
-
71049145217
-
Randomized, double-blind, dose-ranging trial of the oral neurokinin-1 receptor antagonist casopitant mesylate for the prevention of cisplatin-induced nausea and vomiting
-
Roila F, Rolski J, Ramlau R, et al. Randomized, double-blind, dose-ranging trial of the oral neurokinin-1 receptor antagonist casopitant mesylate for the prevention of cisplatin-induced nausea and vomiting. Ann Oncol 2009;20:1867-73
-
(2009)
Ann Oncol
, vol.20
, pp. 1867-73
-
-
Roila, F.1
Rolski, J.2
Ramlau, R.3
-
33
-
-
45349096499
-
Cell motility through plasma membrane blebbing
-
DOI 10.1083/jcb.200802081
-
Fackler OT, Grosse R. Cell motility through plasma membrane blebbing. J Cell Biol 2008;181:879-84 (Pubitemid 351846821)
-
(2008)
Journal of Cell Biology
, vol.181
, Issue.6
, pp. 879-884
-
-
Fackler, O.T.1
Grosse, R.2
-
34
-
-
33749165919
-
Can anesthetic technique for primary breast cancer surgery affect recurrence or metastasis?
-
DOI 10.1097/00000542-200610000-00008, PII 0000054220061000000008
-
Exadaktylos AK, Buggy DJ, Moriarty DC, et al. Can anesthetics technique for primary breast cancer surgery affect recurrence of metastases? Anesthesiology 2006;105:660-4 (Pubitemid 44477309)
-
(2006)
Anesthesiology
, vol.105
, Issue.4
, pp. 660-664
-
-
Exadaktylos, A.K.1
Buggy, D.J.2
Moriarty, D.C.3
Mascha, E.4
Sessler, D.I.5
-
35
-
-
77955653145
-
Paravertebral anesthesia: How substance P and the NK-1 receptor could be involved in regional block and breast cancer recurrence
-
Munoz M, Rosso M, Casinello F, et al. Paravertebral anesthesia: how substance P and the NK-1 receptor could be involved in regional block and breast cancer recurrence. Breast Cancer Res Treat 2010;122:601-3
-
(2010)
Breast Cancer Res Treat
, vol.122
, pp. 601-3
-
-
Munoz, M.1
Rosso, M.2
Casinello, F.3
-
36
-
-
79955611266
-
Synergy between microtubule-destabilizing agents and neurokinin 1 receptor antagonists identified by an siRNA synthetic lethal screen
-
Kitchens CA, McDonald PR, Pollack IF, et al. Synergy between microtubule-destabilizing agents and neurokinin 1 receptor antagonists identified by an siRNA synthetic lethal screen. FASEB J 2009;23:756.13
-
(2009)
FASEB J
, vol.23
, pp. 756-813
-
-
Kitchens, C.A.1
McDonald, P.R.2
Pollack, I.F.3
-
37
-
-
79955621751
-
Efectos de los antagonistas de los receptores NK1 y de la dexametasona sobre la inflamacion neurogenica inducida por ciclofosfamida y por radiacion X en la rata
-
Alfieri AB, Cubeddu LX. Efectos de los antagonistas de los receptores NK1 y de la dexametasona sobre la inflamacion neurogenica inducida por ciclofosfamida y por radiacion X, en la rata. AVFT 2004;23:61-6
-
(2004)
AVFT
, vol.23
, pp. 61-6
-
-
Alfieri, A.B.1
Cubeddu, L.X.2
|