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European Journal of Medicinal Chemistry

Volumn 46, Issue 8, 2011, Pages 3398-3409

Studies on quinones. Part 47. Synthesis of novel phenylaminophenanthridinequinones as potential antitumor agents

(5) Valderrama, Jaime A a,c Ibacache, Andrea a Rodriguez, Jaime A b Theoduloz, Cristina b Benites, Julio c

a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE (Chile)

b UNIVERSIDAD DE TALCA (Chile)

c UNIVERSIDAD ARTURO PRAT (Chile)

Author keywords

Aminophenanthridinequinones; Cytotoxicity; Half wave potentials; Regioselectivity

Indexed keywords

6 PHENYL 8 PHENYLAMINO 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 8 (2 METHOXYPHENYLAMINO) 6 METHYL 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 8 (2,5 DIMETHOXYPHENYLAMINO) 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 8 (2,5 DIMETHOXYPHENYLAMINO) 6 METHYL 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 8 (4 HYDROXYPHENYLAMINO) 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 8 (4 HYDROXYPHENYLAMINO) 6 METHYL 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 8 (4 METHOXYPHENYLAMINO) 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 8 (4 METHOXYPHENYLAMINO) 6 METHYL 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 8 (N ETHYLPHENYLAMINO) 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 8 (N METHYLPHENYLAMINO) 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 8 (PHENYLAMINO) 6 METHYL 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 8 PHENYLAMINO 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 8 PHENYLAMINO 6 (2 FURYL) 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 9 (2,5 DIMETHOXYPHENYLAMINO) 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 9 (4 HYDROXYPHENYLAMINO) 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 9 (4 METHOXYPHENYLAMINO) 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 9 (N ETHYLPHENYLAMINO) 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 9 (N METHYLPHENYLAMINO) 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; 9 PHENYLAMINO 3,4 DIHYDROPHENANTHRIDINE 1,7,10(2H) TRIONE; ACID; ALDEHYDE; ANILINE DERIVATIVE; ANTHRAQUINONE DERIVATIVE; ANTINEOPLASTIC AGENT; BENZOQUINONE; FUNCTIONAL GROUP; HYDROQUINONE DERIVATIVE; NITROGEN; PHENYLAMINOPHENANTHRIDINEQUINONE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACYLATION; AMINATION; ANTINEOPLASTIC ACTIVITY; AROMATIZATION; ARTICLE; CANCER CELL CULTURE; COLORIMETRY; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; ONE POT SYNTHESIS; PHARMACOPHORE; PHOTOACYLATION; STRUCTURE ACTIVITY RELATION;

ANILINE COMPOUNDS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; FIBROBLASTS; HUMANS; INHIBITORY CONCENTRATION 50; LUNG NEOPLASMS; MOLECULAR STRUCTURE; PHENANTHRIDINES; QUINONES; STOMACH NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP; URINARY BLADDER NEOPLASMS;

EID: 79958260353 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2011.05.003 Document Type: Article

Times cited : (28)

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