-
2
-
-
48249125791
-
Malignant gliomas in adults
-
Wen PY, Kesari S (2008) Malignant gliomas in adults. N Engl J Med 359:492-507
-
(2008)
N Engl J Med
, vol.359
, pp. 492-507
-
-
Wen, P.Y.1
Kesari, S.2
-
3
-
-
33847336870
-
Molecular targets of glioma invasion
-
doi:10.1007/s00018-007-6342-5
-
Nakada M, Nakada S, Demuth T, Tran NL, Hoelzinger DB, Berens ME (2007) Molecular targets of glioma invasion. Cell Mol Life Sci 64:458-478. doi:10.1007/s00018-007-6342-5
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 458-478
-
-
Nakada, M.1
Nakada, S.2
Demuth, T.3
Tran, N.L.4
Hoelzinger, D.B.5
Berens, M.E.6
-
4
-
-
33747433675
-
Signal transduction of sphingosine-1-phosphate G protein-coupled receptors
-
doi:910.1100/tsw.2006.1182
-
Young N, Van Brocklyn JR (2006) Signal transduction of sphingosine-1-phosphate G protein-coupled receptors. ScientificWorldJournal 6:946-966. doi:910.1100/tsw.2006.1182
-
(2006)
ScientificWorldJournal
, vol.6
, pp. 946-966
-
-
Young, N.1
Van Brocklyn, J.R.2
-
5
-
-
23844498431
-
Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: Roles of sphingosine kinase isoforms in growth of glioblastoma cell lines
-
Van Brocklyn JR, Jackson CA, Pearl DK, Kotur MS, Snyder PJ, Prior TW (2005) Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme. Roles of sphingosine kinase isoforms in growth of glioblastoma cell lines. J Neuropathol Exp Neurol 64:695-705 (Pubitemid 41177111)
-
(2005)
Journal of Neuropathology and Experimental Neurology
, vol.64
, Issue.8
, pp. 695-705
-
-
Van Brooklyn, J.R.1
Jackson, C.A.2
Pearl, D.K.3
Kotur, M.S.4
Snyder, P.J.5
Prior, T.W.6
-
6
-
-
34247174943
-
Roles of sphingosine- 1-phosphate (S1P) receptors in malignant behavior of glioma cells. Differential effects of S1P2 on cell migration and invasiveness
-
Young N, Van Brocklyn JR (2007) Roles of sphingosine- 1-phosphate (S1P) receptors in malignant behavior of glioma cells. Differential effects of S1P2 on cell migration and invasiveness. Exp Cell Res 313:1615-1627
-
(2007)
Exp Cell Res
, vol.313
, pp. 1615-1627
-
-
Young, N.1
Van Brocklyn, J.R.2
-
7
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
Salomon DS, Brandt R, Ciardiello F, Normanno N (1995) Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 19:183-232
-
(1995)
Crit Rev Oncol Hematol
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
Normanno, N.4
-
8
-
-
0033392005
-
Epidermal growth factor receptor inhibition in cancer therapy: Biology, rationale and preliminary clinical results
-
Huang SM, Harari PM (1999) Epidermal growth factor receptor inhibition in cancer therapy: biology, rationale and preliminary clinical results. Invest New Drugs 17:259-269
-
(1999)
Invest New Drugs
, vol.17
, pp. 259-269
-
-
Huang, S.M.1
Harari, P.M.2
-
10
-
-
0034163550
-
Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas
-
Frederick L, Wang XY, Eley G, James CD (2000) Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas. Cancer Res 60:1383-1387 (Pubitemid 30152011)
-
(2000)
Cancer Research
, vol.60
, Issue.5
, pp. 1383-1387
-
-
Frederick, L.1
Wang, X.-Y.2
Eley, G.3
James, C.D.4
-
11
-
-
47049086333
-
Targeting the epidermal growth factor receptor in high-grade astrocytomas
-
Voelzke WR, Petty WJ, Lesser GJ (2008) Targeting the epidermal growth factor receptor in high-grade astrocytomas. Curr Treat Options Oncol 9:23-31
-
(2008)
Curr Treat Options Oncol
, vol.9
, pp. 23-31
-
-
Voelzke, W.R.1
Petty, W.J.2
Lesser, G.J.3
-
12
-
-
67349137902
-
The EGFRvIII variant in glioblastoma multiforme
-
Gan HK, Kaye AH, Luwor RB (2009) The EGFRvIII variant in glioblastoma multiforme. J Clin Neurosci 16:748-754
-
(2009)
J Clin Neurosci
, vol.16
, pp. 748-754
-
-
Gan, H.K.1
Kaye, A.H.2
Luwor, R.B.3
-
13
-
-
0034954124
-
The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy
-
Pedersen MW, Meltorn M, Damstrup L, Poulsen HS (2001) The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy. Ann Oncol 12:745-760
-
(2001)
Ann Oncol
, vol.12
, pp. 745-760
-
-
Pedersen, M.W.1
Meltorn, M.2
Damstrup, L.3
Poulsen, H.S.4
-
14
-
-
7144227965
-
Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials
-
DOI 10.1023/A:1008209720526
-
Voldborg BR, Damstrup L, Spang-Thomsen M, Poulsen HS (1997) Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials. Ann Oncol 8:1197-1206 (Pubitemid 28164074)
-
(1997)
Annals of Oncology
, vol.8
, Issue.12
, pp. 1197-1206
-
-
Rude, V.B.1
Damstrup, L.2
Spang-Thomsen, M.3
Skovgaard, P.H.4
-
15
-
-
66349124729
-
Sphingosine-1-phosphate: The Swiss army knife of sphingolipid signaling
-
Maceyka M, Milstien S, Spiegel S (2009) Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signaling. J Lipid Res 50 Suppl:S272-S276
-
(2009)
J Lipid Res
, vol.50
, Issue.SUPPL.
-
-
Maceyka, M.1
Milstien, S.2
Spiegel, S.3
-
16
-
-
11244293572
-
Isolation of cancer stem cells from adult glioblastoma multiforme
-
DOI 10.1038/sj.onc.1208311
-
Yuan X, Curtin J, Xiong Y, Liu G, Waschsmann-Hogiu S, Farkas DL, Black KL, Yu JS (2004) Isolation of cancer stem cells from adult glioblastoma multiforme. Oncogene 23:9392-9400. doi: 10.1038/sj.onc.1208311 (Pubitemid 40069671)
-
(2004)
Oncogene
, vol.23
, Issue.58
, pp. 9392-9400
-
-
Yuan, X.1
Curtin, J.2
Xiong, Y.3
Liu, G.4
Waschsmann-Hogiu, S.5
Farkas, D.L.6
Black, K.L.7
Yu, J.S.8
-
17
-
-
4944250781
-
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
-
DOI 10.1158/0008-5472.CAN-04-1364
-
Galli R, Binda E, Orfanelli U, Cipelletti B, Gritti A, De Vitis S, Fiocco R, Foroni C, Dimeco F, Vescovi A (2004) Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res 64:7011-7021 (Pubitemid 39331011)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 7011-7021
-
-
Galli, R.1
Binda, E.2
Orfanelli, U.3
Cipelletti, B.4
Gritti, A.5
De Vitis, S.6
Fiocco, R.7
Foroni, C.8
Dimeco, F.9
Vescovi, A.10
-
18
-
-
33646358694
-
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
-
DOI 10.1016/j.ccr.2006.03.030, PII S1535610806001176
-
Lee J, Kotliarova S, Kotliarov Y, Li A, Su Q, Donin NM, Pastorino S, Purow BW, Christopher N, Zhang W, Park JK, Fine HA (2006) Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 9:391-403 (Pubitemid 43668737)
-
(2006)
Cancer Cell
, vol.9
, Issue.5
, pp. 391-403
-
-
Lee, J.1
Kotliarova, S.2
Kotliarov, Y.3
Li, A.4
Su, Q.5
Donin, N.M.6
Pastorino, S.7
Purow, B.W.8
Christopher, N.9
Zhang, W.10
Park, J.K.11
Fine, H.A.12
-
19
-
-
54449086337
-
Human cytomegalovirus regulates bioactive sphingolipids
-
Machesky NJ, Zhang G, Raghavan B, Zimmerman P, Kelly SL, Merrill AH Jr, Waldman WJ, Van Brocklyn JR, Trgovcich J (2008) Human cytomegalovirus regulates bioactive sphingolipids. J Biol Chem 283:26148-26160
-
(2008)
J Biol Chem
, vol.283
, pp. 26148-26160
-
-
Machesky, N.J.1
Zhang, G.2
Raghavan, B.3
Zimmerman, P.4
Kelly, S.L.5
Merrill Jr., A.H.6
Waldman, W.J.7
Van Brocklyn, J.R.8
Trgovcich, J.9
-
20
-
-
31544454386
-
Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells
-
DOI 10.1158/0008-5472.CAN-05-2753
-
Ramnarain DB, Park S, Lee DY, Hatanpaa KJ, Scoggin SO, Otu H, Libermann TA, Raisanen JM, Ashfaq R, Wong ET, Wu J, Elliott R, Habib AA (2006) Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells. Cancer Res 66:867-874 (Pubitemid 43165952)
-
(2006)
Cancer Research
, vol.66
, Issue.2
, pp. 867-874
-
-
Ramnarain, D.B.1
Park, S.2
Lee, D.Y.3
Hatanpaa, K.J.4
Scoggin, S.O.5
Otu, H.6
Libermann, T.A.7
Raisanen, J.M.8
Ashfaq, R.9
Wong, E.T.10
Wu, J.11
Elliott, R.12
Habib, A.A.13
-
21
-
-
0032508706
-
Molecular cloning and functional characterization of murine sphingosine kinase
-
DOI 10.1074/jbc.273.37.23722
-
Kohama T, Olivera A, Edsall L, Nagiec MM, Dickson R, Spiegel S (1998) Molecular cloning and functional characterization of murine sphingosine kinase. J Biol Chem 273:23722-23728 (Pubitemid 28435703)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.37
, pp. 23722-23728
-
-
Kohama, T.1
Olivera, A.2
Edsall, L.3
Nagiec, M.M.4
Dickson, R.5
Spiegel, S.6
-
22
-
-
38949117993
-
Development of a real-time RT-PCR assay for detecting EGFRvIII in glioblastoma samples
-
DOI 10.1158/1078-0432.CCR-07-1966
-
Yoshimoto K, Dang J, Zhu S, Nathanson D, Huang T, Dumont R, Seligson DB, Yong WH, Xiong Z, Rao N, Winther H, Chakravarti A, Bigner DD, Mellinghoff IK, Horvath S, Cavenee WK, Cloughesy TF, Mischel PS (2008) Development of a real-time RT-PCR assay for detecting EGFRvIII in glioblastoma samples. Clin Cancer Res 14:488-493 (Pubitemid 351226117)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.2
, pp. 488-493
-
-
Yoshimoto, K.1
Dang, J.2
Zhu, S.3
Nathanson, D.4
Huang, T.5
Dumont, R.6
Seligson, D.B.7
Yong, W.H.8
Xiong, Z.9
Rao, N.10
Winther, H.11
Chakravarti, A.12
Bigner, D.D.13
Mellinghoff, I.K.14
Horvath, S.15
Cavenee, W.K.16
Cloughesy, T.F.17
Mischel, P.S.18
-
23
-
-
41249103991
-
Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells: Role of hypoxia-inducible factors 1 and 2
-
Anelli VV, Gault CR, Cheng AB, Obeid LM (2008) Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells: role of hypoxia-inducible factors 1 and 2. J Biol Chem 283:3365-3375
-
(2008)
J Biol Chem
, vol.283
, pp. 3365-3375
-
-
Anelli, V.V.1
Gault, C.R.2
Cheng, A.B.3
Obeid, L.M.4
-
24
-
-
57349160348
-
Exploring multi-targeting strategies for the treatment of gliomas
-
Omuro AM (2008) Exploring multi-targeting strategies for the treatment of gliomas. Curr Opin Investig Drugs 9:1287-1295
-
(2008)
Curr Opin Investig Drugs
, vol.9
, pp. 1287-1295
-
-
Omuro, A.M.1
-
25
-
-
51349083585
-
Tumor-specific immunotherapy targeting the EGFRvIII mutation in patients with malignant glioma
-
Sampson JH, Archer GE, Mitchell DA, Heimberger AB, Bigner DD (2008) Tumor-specific immunotherapy targeting the EGFRvIII mutation in patients with malignant glioma. Semin Immunol 20:267-275
-
(2008)
Semin Immunol
, vol.20
, pp. 267-275
-
-
Sampson, J.H.1
Archer, G.E.2
Mitchell, D.A.3
Heimberger, A.B.4
Bigner, D.D.5
-
26
-
-
0141507968
-
Discovery and evaluation of inhibitors of human sphingosine kinase
-
French KJ, Schrecengost RS, Lee BD, Zhuang Y, Smith SN, Eberly JL, Yun JK, Smith CD (2003) Discovery and evaluation of inhibitors of human sphingosine kinase. Cancer Res 63:2969-5962
-
(2003)
Cancer Res
, vol.63
, pp. 2969-5962
-
-
French, K.J.1
Schrecengost, R.S.2
Lee, B.D.3
Zhuang, Y.4
Smith, S.N.5
Eberly, J.L.6
Yun, J.K.7
Smith, C.D.8
-
27
-
-
31044450344
-
The epidermal growth factor stimulates sphingosine kinase-1 expression and activity in the human mammary carcinoma cell line MCF7
-
DOI 10.1016/j.bbalip.2005.12.001, PII S1388198105002908
-
Döll F, Pfeilschifter J, Huwiler A (2005) The epidermal growth factor stimulates sphingosine kinase-1 expression and activity in the human mammary carcinoma cell line MCF7. Biochim Biophys Acta 1738:72-81 (Pubitemid 43122132)
-
(2005)
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
, vol.1738
, Issue.1-3
, pp. 72-81
-
-
Doll, F.1
Pfeilschifter, J.2
Huwiler, A.3
-
28
-
-
63149167365
-
Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patients
-
Li W, Yu CP, Xia JT, Zhang L, Weng GX, Zheng HQ, Kong QL, Hu LJ, Zeng MS, Zeng YX, Li M, Li J, Song LB (2009) Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patients. Clin Cancer Res 15:1393-1399
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1393-1399
-
-
Li, W.1
Yu, C.P.2
Xia, J.T.3
Zhang, L.4
Weng, G.X.5
Zheng, H.Q.6
Kong, Q.L.7
Hu, L.J.8
Zeng, M.S.9
Zeng, Y.X.10
Li, M.11
Li, J.12
Song, L.B.13
-
29
-
-
52949143502
-
Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer
-
Ruckhäberle E, Rody A, Engels K, Gaetje R, von Minckwitz G, Schiffmann S, Grösch S, Geisslinger G, Holtrich U, Karn T, Kaufmann M (2007) Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer. Breast Cancer Res Treat 112:41-52
-
(2007)
Breast Cancer Res Treat
, vol.112
, pp. 41-52
-
-
Ruckhäberle, E.1
Rody, A.2
Engels, K.3
Gaetje, R.4
Von Minckwitz, G.5
Schiffmann, S.6
Grösch, S.7
Geisslinger, G.8
Holtrich, U.9
Karn, T.10
Kaufmann, M.11
-
30
-
-
33644526361
-
Sphingosine kinase 1 is up-regulated in colon carcinogenesis
-
DOI 10.1096/fj.05-4331fje
-
Kawamori T, Osta W, Johnson KR, Pettus BJ, Bielawski J, Tanaka T, Wargovich MJ, Reddy BS, Hannun YA, Obeid LM, Zhou D (2006) Sphingosine kinase 1 is up-regulated in colon carcinogenesis. FASEB J 20:386-388 (Pubitemid 46671180)
-
(2006)
FASEB Journal
, vol.20
, Issue.2
, pp. 386-388
-
-
Kawamori, T.1
Osta, W.2
Johnson, K.R.3
Pettus, B.J.4
Bielawski, J.5
Tanaka, T.6
Wargovich, M.J.7
Reddy, B.S.8
Hannun, Y.A.9
Obeid, L.M.10
Zhou, D.11
-
31
-
-
33749185077
-
Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation
-
DOI 10.1128/MCB.02341-05
-
Kohno M, Momoi M, Oo ML, Paik JH, Lee YM, Venkataraman K, Ai Y, Ristimaki AP, Fyrst H, Sano H, Rosenberg D, Saba JD, Proia RL, Hla T (2006) Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation. Mol Cell Biol 26:7211-7223 (Pubitemid 44477697)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.19
, pp. 7211-7223
-
-
Kohno, M.1
Momoi, M.2
Oo, M.L.3
Paik, J.-H.4
Lee, Y.-M.5
Venkataraman, K.6
Ai, Y.7
Ristimaki, A.P.8
Fyrst, H.9
Sano, H.10
Rosenberg, D.11
Saba, J.D.12
Proia, R.L.13
Hla, T.14
-
32
-
-
23944509761
-
Overexpression of sphingosine kinase 1 is an oncogenic event in erythroleukemic progression
-
DOI 10.1182/blood-2004-12-4832
-
Le Scolan E, Pchejetski D, Banno Y, Denis N, Mayeux P, Vainchenker W, Levade T, Moreau-Gachelin F (2005) Overexpression of sphingosine kinase 1 is an oncogenic event in erythroleukemic progression. Blood 106:1808-1816 (Pubitemid 41208598)
-
(2005)
Blood
, vol.106
, Issue.5
, pp. 1808-1816
-
-
Le, S.E.1
Pchejetski, D.2
Banno, Y.3
Denis, N.4
Mayeux, P.5
Vainchenker, W.6
Levade, T.7
Moreau-Gachelin, F.8
-
33
-
-
58149231552
-
Clinical significance of sphingosine kinase-1 expression in human astrocytomas progression and overall patient survival
-
Li J, Guan HY, Gong LY, Song LB, Zhang N, Wu J, Yuan J, Zheng YJ, Huang ZS, Li M (2008) Clinical significance of sphingosine kinase-1 expression in human astrocytomas progression and overall patient survival. Clin Cancer Res 14:6996-7003
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6996-7003
-
-
Li, J.1
Guan, H.Y.2
Gong, L.Y.3
Song, L.B.4
Zhang, N.5
Wu, J.6
Yuan, J.7
Zheng, Y.J.8
Huang, Z.S.9
Li, M.10
-
34
-
-
63649164236
-
Interleukin-1 regulates the expression of sphingosine kinase 1 in glioblastoma cells
-
Paugh BS, Bryan L, Paugh SW, Wilczynska KM, Alvarez SM, Singh SK, Kapitonov D, Rokita H, Wright S, Griswold-Prenner I, Milstien S, Spiegel S, Kordula T (2009) Interleukin-1 regulates the expression of sphingosine kinase 1 in glioblastoma cells. J Biol Chem 284:3408-3417
-
(2009)
J Biol Chem
, vol.284
, pp. 3408-3417
-
-
Paugh, B.S.1
Bryan, L.2
Paugh, S.W.3
Wilczynska, K.M.4
Alvarez, S.M.5
Singh, S.K.6
Kapitonov, D.7
Rokita, H.8
Wright, S.9
Griswold-Prenner, I.10
Milstien, S.11
Spiegel, S.12
Kordula, T.13
-
35
-
-
38949105094
-
EGF regulates plasminogen activator inhibitor-1 (PAI-1) by a pathway involving c-Src, PKCd, and sphingosine kinase 1 in glioblastoma cells
-
Paugh BS, Paugh SW, Bryan L, Kapitonov D, Wilczynska KM, Gopalan SM, Rokita H, Milstien S, Spiegel S, Kordula T (2007) EGF regulates plasminogen activator inhibitor-1 (PAI-1) by a pathway involving c-Src, PKCd, and sphingosine kinase 1 in glioblastoma cells. FASEB J 22:455-465
-
(2007)
FASEB J
, vol.22
, pp. 455-465
-
-
Paugh, B.S.1
Paugh, S.W.2
Bryan, L.3
Kapitonov, D.4
Wilczynska, K.M.5
Gopalan, S.M.6
Rokita, H.7
Milstien, S.8
Spiegel, S.9
Kordula, T.10
-
36
-
-
25844457390
-
Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells
-
DOI 10.1016/j.febslet.2005.08.055, PII S0014579305010677
-
Sarkar S, Maceyka M, Hait NC, Paugh SW, Sankala H, Milstien S, Spiegel S (2005) Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells. FEBS Lett 579:5313-5317 (Pubitemid 41395149)
-
(2005)
FEBS Letters
, vol.579
, Issue.24
, pp. 5313-5317
-
-
Sarkar, S.1
Maceyka, M.2
Hait, N.C.3
Paugh, S.W.4
Sankala, H.5
Milstien, S.6
Spiegel, S.7
-
37
-
-
14644412873
-
Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients
-
DOI 10.1158/1078-0432.CCR-04-1737
-
Heimberger AB, Hlatky R, Suki D, Yang D, Weinberg J, Gilbert M, Sawaya R, Aldape K (2005) Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients. Clin Cancer Res 11:1462-1466 (Pubitemid 40315227)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.4
, pp. 1462-1466
-
-
Heimberger, A.B.1
Hlatky, R.2
Suki, D.3
Yang, D.4
Weinberg, J.5
Gilbert, M.6
Sawaya, R.7
Aldape, K.8
-
38
-
-
8844239960
-
Sphingosine 1-phosphate transactivates c-Met as well as epidermal growth factor receptor (EGFR) in human gastric cancer cells
-
DOI 10.1016/j.febslet.2004.10.024, PII S001457930401258X
-
Shida D, Kitayama J, Yamaguchi H, Yamashita H, Mori K, Watanabe T, Yatomi Y, Nagawa H (2004) Sphingosine 1-phosphate transactivates c-Met as well as epidermal growth factor receptor (EGFR) in human gastric cancer cells. FEBS Lett 577:333-338 (Pubitemid 39535309)
-
(2004)
FEBS Letters
, vol.577
, Issue.3
, pp. 333-338
-
-
Shida, D.1
Kitayama, J.2
Yamaguchi, H.3
Yamashita, H.4
Mori, K.5
Watanabe, T.6
Yatomi, Y.7
Nagawa, H.8
-
39
-
-
53049096639
-
Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion
-
Shida D, Fang X, Kordula T, Takabe K, Lepine S, Alvarez SE, Milstien S, Spiegel S (2008) Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion. Cancer Res 68:6569-6577
-
(2008)
Cancer Res
, vol.68
, pp. 6569-6577
-
-
Shida, D.1
Fang, X.2
Kordula, T.3
Takabe, K.4
Lepine, S.5
Alvarez, S.E.6
Milstien, S.7
Spiegel, S.8
-
40
-
-
41849084505
-
Sphingosine 1-phosphate induces EGFR expression via Akt/NF-jB and ERK/AP-1 pathways in rat vascular smooth muscle cells
-
Hsieh HL, Sun CC, Wu CB, Wu CY, Tung WH, Wang HH, Yang CM (2007) Sphingosine 1-phosphate induces EGFR expression via Akt/NF-jB and ERK/AP-1 pathways in rat vascular smooth muscle cells. J Cell Biochem 103:1732-1746
-
(2007)
J Cell Biochem
, vol.103
, pp. 1732-1746
-
-
Hsieh, H.L.1
Sun, C.C.2
Wu, C.B.3
Wu, C.Y.4
Tung, W.H.5
Wang, H.H.6
Yang, C.M.7
-
41
-
-
33646117016
-
Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: The role of sphingosine kinase-1
-
Sukocheva O, Wadham C, Holmes A, Albanese N, Verrier E, Feng F, Bernal A, Derian CK, Ullrich A, Vadas MA, Xia P (2006) Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1. J Cell Biol 173:301-310
-
(2006)
J Cell Biol
, vol.173
, pp. 301-310
-
-
Sukocheva, O.1
Wadham, C.2
Holmes, A.3
Albanese, N.4
Verrier, E.5
Feng, F.6
Bernal, A.7
Derian, C.K.8
Ullrich, A.9
Vadas, M.A.10
Xia, P.11
-
42
-
-
0030780015
-
Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation
-
Edsall LC, Pirianov GG, Spiegel S (1997) Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation. J Neurosci 17:6952-6960 (Pubitemid 27427874)
-
(1997)
Journal of Neuroscience
, vol.17
, Issue.18
, pp. 6952-6960
-
-
Edsall, L.C.1
Pirianov, G.G.2
Spiegel, S.3
-
43
-
-
0030728721
-
Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors
-
DOI 10.1016/S0014-5793(97)01277-5, PII S0014579397012775
-
Rius RA, Edsall LC, Spiegel S (1997) Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors. FEBS Lett 417:173-176 (Pubitemid 27491727)
-
(1997)
FEBS Letters
, vol.417
, Issue.2
, pp. 173-176
-
-
Rius, R.A.1
Edsall, L.C.2
Spiegel, S.3
-
44
-
-
34248219175
-
Sphingosine kinase 1 expression is regulated by signaling through PI3 K, AKT2, and mTOR in human coronary artery smooth muscle cells
-
Francy JM, Nag A, Conroy EJ, Hengst JA, Yun JK (2007) Sphingosine kinase 1 expression is regulated by signaling through PI3 K, AKT2, and mTOR in human coronary artery smooth muscle cells. Biochim Biophys Acta 1769:253-265
-
(2007)
Biochim Biophys Acta
, vol.1769
, pp. 253-265
-
-
Francy, J.M.1
Nag, A.2
Conroy, E.J.3
Hengst, J.A.4
Yun, J.K.5
-
45
-
-
34547867758
-
RET signaling-induced SPHK1 gene expression plays a role in both GDNF-induced differentiation and MEN2-type oncogenesis
-
DOI 10.1111/j.1471-4159.2007.04673.x
-
Murakami M, Ichihara M, Sobue S, Kikuchi R, Ito H, Kimura A, Iwasaki T, Takagi A, Kojima T, Takahashi M, Suzuki M, Banno Y, Nozawa Y, Murate T (2007) RET signaling-induced SPHK1 gene expression plays a role in both GDNF-induced differentiation and MEN2-type oncogenesis. J Neurochem 102:1585-1594 (Pubitemid 47256200)
-
(2007)
Journal of Neurochemistry
, vol.102
, Issue.5
, pp. 1585-1594
-
-
Murakami, M.1
Ichihara, M.2
Sobue, S.3
Kikuchi, R.4
Ito, H.5
Kimura, A.6
Iwasaki, T.7
Takagi, A.8
Kojima, T.9
Takahashi, M.10
Suzuki, M.11
Banno, Y.12
Nozawa, Y.13
Murate, T.14
-
46
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW et al (2008) An integrated genomic analysis of human glioblastoma multiforme. Science 321:1807-1812
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
-
47
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
McLendon R et al (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455:1061-1068
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
McLendon, R.1
-
48
-
-
0028146767
-
A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity
-
DOI 10.1073/pnas.91.16.7727
-
Nishikawa R, Ji XD, Harmon RC, Lazar CS, Gill GN, Cavenee WK, Huang HJ (1994) A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity. Proc Natl Acad Sci USA 91:7727-7731 (Pubitemid 24238258)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.16
, pp. 7727-7731
-
-
Nishikawa, R.1
Ji, X.-D.2
Harmon, R.C.3
Lazar, C.S.4
Gill, G.N.5
Cavenee, W.K.6
Huang, H.-J.S.7
-
49
-
-
62449252775
-
Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis
-
Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Pfannl R, Bronson RT, Chen JW, Weissleder R, Housman DE, Charest A (2009) Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis. Proc Natl Acad Sci USA 106:2712-2716
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2712-2716
-
-
Zhu, H.1
Acquaviva, J.2
Ramachandran, P.3
Boskovitz, A.4
Woolfenden, S.5
Pfannl, R.6
Bronson, R.T.7
Chen, J.W.8
Weissleder, R.9
Housman, D.E.10
Charest, A.11
-
50
-
-
77953923379
-
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
-
Alvarez SE, Harikumar KB, Hait NC, Allegood J, Strub GM, Kim EY, Maceyka M, Jiang H, Luo C, Kordula T, Milstien S, Spiegel S (2010) Sphingosine-1- phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature 465:1084-1088
-
(2010)
Nature
, vol.465
, pp. 1084-1088
-
-
Alvarez, S.E.1
Harikumar, K.B.2
Hait, N.C.3
Allegood, J.4
Strub, G.M.5
Kim, E.Y.6
Maceyka, M.7
Jiang, H.8
Luo, C.9
Kordula, T.10
Milstien, S.11
Spiegel, S.12
-
51
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
DOI 10.1038/nature05236, PII NATURE05236
-
Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, Dewhirst MW, Bigner DD, Rich JN (2006) Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444:756-760 (Pubitemid 44949604)
-
(2006)
Nature
, vol.444
, Issue.7120
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
52
-
-
46449115281
-
Stem cell-related ''self-renewal'' signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma
-
Murat A, Migliavacca E, Gorlia T, Lambiv WL, Shay T, Hamou MF, de Tribolet N, Regli L, Wick W, Kouwenhoven MC, Hainfellner JA, Heppner FL, Dietrich PY, Zimmer Y, Cairncross JG, Janzer RC, Domany E, Delorenzi M, Stupp R, Hegi ME (2008) Stem cell-related ''self-renewal'' signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma. J Clin Oncol 26:3015-3024
-
(2008)
J Clin Oncol
, vol.26
, pp. 3015-3024
-
-
Murat, A.1
Migliavacca, E.2
Gorlia, T.3
Lambiv, W.L.4
Shay, T.5
Hamou, M.F.6
De Tribolet, N.7
Regli, L.8
Wick, W.9
Kouwenhoven, M.C.10
Hainfellner, J.A.11
Heppner, F.L.12
Dietrich, P.Y.13
Zimmer, Y.14
Cairncross, J.G.15
Janzer, R.C.16
Domany, E.17
Delorenzi, M.18
Stupp, R.19
Hegi, M.E.20
more..
-
53
-
-
33845671339
-
Analysis of gene expression and chemoresistance of CD133? Cancer stem cells in glioblastoma
-
doi:10.1186/1476-4598-1185-1167
-
Liu G, Yuan X, Zeng Z, Tunici P, Ng H, Abdulkadir IR, Lu L, Irvin D, Black KL, Yu JS (2006) Analysis of gene expression and chemoresistance of CD133? cancer stem cells in glioblastoma. Mol Cancer 5:67. doi:10.1186/1476-4598-1185- 1167
-
(2006)
Mol Cancer
, vol.5
, pp. 67
-
-
Liu, G.1
Yuan, X.2
Zeng, Z.3
Tunici, P.4
Ng, H.5
Abdulkadir, I.R.6
Lu, L.7
Irvin, D.8
Black, K.L.9
Yu, J.S.10
-
54
-
-
58149277751
-
Roles of bioactive sphingolipids in cancer biology and therapeutics
-
Saddoughi SA, Song P, Ogretmen B (2008) Roles of bioactive sphingolipids in cancer biology and therapeutics. Subcell Biochem 49:413-440
-
(2008)
Subcell Biochem
, vol.49
, pp. 413-440
-
-
Saddoughi, S.A.1
Song, P.2
Ogretmen, B.3
-
55
-
-
79958242497
-
Lipids in neural tumors
-
Lajtha A (ed) 3rd edn. Springer-Verlag, Heidelberg, Germany, doi:10.1007/978-0-387-30378-9-21
-
Van Brocklyn JR (2009) Lipids in neural tumors. In: Lajtha A (ed) Handbook of neurochemistry and molecular neurobiology, neural lipids, 3rd edn. Springer-Verlag, Heidelberg, Germany, pp 535-561. doi:10.1007/978-0-387-30378-9- 21
-
(2009)
Handbook of Neurochemistry and Molecular Neurobiology, Neural Lipids
, pp. 535-561
-
-
Van Brocklyn, J.R.1
-
56
-
-
33845291120
-
Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases
-
DOI 10.1016/j.bbamem.2006.08.007, PII S0005273606003130, Sphingolipids, Apoptosis and Disease
-
Hait NC, Oskeritzian CA, Paugh SW, Milstien S, Spiegel S (2006) Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases. Biochim Biophys Acta 1758:2016-2026 (Pubitemid 44879368)
-
(2006)
Biochimica et Biophysica Acta - Biomembranes
, vol.1758
, Issue.12
, pp. 2016-2026
-
-
Hait, N.C.1
Oskeritzian, C.A.2
Paugh, S.W.3
Milstien, S.4
Spiegel, S.5
-
57
-
-
48449100702
-
Downregulating sphingosine kinase-1 for cancer therapy
-
Cuvillier O (2008) Downregulating sphingosine kinase-1 for cancer therapy. Expert Opin Ther Targets 12:1009-1020
-
(2008)
Expert Opin Ther Targets
, vol.12
, pp. 1009-1020
-
-
Cuvillier, O.1
-
58
-
-
52449092057
-
Targeting SphK1 as a new strategy against cancer
-
Shida D, Takabe K, Kapitonov D, Milstien S, Spiegel S (2008) Targeting SphK1 as a new strategy against cancer. Curr Drug Targets 9:662-673
-
(2008)
Curr Drug Targets
, vol.9
, pp. 662-673
-
-
Shida, D.1
Takabe, K.2
Kapitonov, D.3
Milstien, S.4
Spiegel, S.5
|