A reliable method of liquid chromatography for the quantification of acetaminophen and identification of its toxic metabolite N-acetyl-p-benzoquinoneimine for application in pediatric studies

Biomedical Chromatography

Volumn 25, Issue 7, 2011, Pages 760-766

  Flores Pérez, Carmen ^a   Chávez Pacheco, Juan Luis ^a   Ramírez Mendiola, Blanca ^a   Alemón Medina, Radamés ^a   García Álvarez, Raquel ^a   Juárez Olguín, Hugo ^a,b   Flores Pérez, Janett ^a,b  

^a INSTITUTO NACIONAL DE PEDIATRÍA   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Acetaminophen; HPLC; N acetyl benzoquinoneimine; Pediatric population

Indexed keywords

LIQUID CHROMATOGRAPHY; METABOLITES; PATIENT MONITORING;

ACETAMINOPHEN; BENZOQUINONEIMINE; DRUG MONITORING; HPLC; N ACETYLS; N-ACETYL BENZOQUINONEIMINE; PEDIATRIC POPULATION; PLASMA SAMPLES; RELIABLE METHODS; TOXIC METABOLITES;

PEDIATRICS;

FORMIC ACID; METHANOL; N ACETYL 1,4 BENZOQUINONE IMINE; PARACETAMOL; WATER;

ADOLESCENT; ARTICLE; CHILD; CLINICAL ARTICLE; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG MONITORING; DRUG SELECTIVITY; ELUTION; FEMALE; HUMAN; INFANT; LIQUID CHROMATOGRAPHY; MALE; PEDIATRICS; PLASMA; PRESCHOOL CHILD; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCHOOL CHILD; ULTRAVIOLET RADIATION;

EID: 79958224004     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1511     Document Type: Article

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