Enhanced binding and killing of target tumor cells by drug-loaded liposomes modified with tumor-specific phage fusion coat protein

Nanomedicine

Volumn 5, Issue 4, 2010, Pages 563-574

  Wang, Tao ^a   Dsouza, Gerard Gm ^a,b   Bedi, Deepa ^c   Fagbohun, Olusegun A ^c   Potturi, L Prasanna ^c   Papahadjopoulos Sternberg, Brigitte ^d   Petrenko, Valery A ^c   Torchilin, Vladimir P ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

^b MASSACHUSETTS COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

^c AUBURN UNIVERSITY   (United States)

^d NanoAnalytical Laboratory   (United States)

Author keywords

Breast cancer; Doxil ; Drug delivery; Landscape phage; Liposome; Major coat protein pVIII; Phage display; Tumor targeting

Indexed keywords

COAT PROTEIN; DOXORUBICIN; LIPOSOME; MACROGOL;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BINDING AFFINITY; BREAST CANCER; CANCER CELL CULTURE; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG SELECTIVITY; DRUG SPECIFICITY; DRUG TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPOSOMAL DELIVERY; MOUSE; NONHUMAN; PARTICLE SIZE; PHAGE DISPLAY; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; BACTERIOPHAGES; BLOTTING, WESTERN; CAPSID PROTEINS; CELL LINE, TUMOR; DOXORUBICIN; DRUG CARRIERS; FREEZE FRACTURING; HUMANS; LIPOSOMES; MOLECULAR SEQUENCE DATA; NEOPLASMS;

EID: 77953394893     PISSN: 17435889     EISSN: None     Source Type: Journal    
DOI: 10.2217/nnm.10.30     Document Type: Article

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