G-CSF and erythropoietin combination therapy for infarct repair: Two plus two equals two? Editorial to: "Cytokine combination theray with erythropoietin and granulocyte colony stimulating factor in a porcine model of acute myocardial infarction" by F.S. Angeli et al.

Cardiovascular Drugs and Therapy

Volumn 24, Issue 5-6, 2010, Pages 369-371

  Quinn, Carrie M ^a   Dawn, Buddhadeb ^a  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; GRANULOCYTE COLONY STIMULATING FACTOR;

ACUTE HEART INFARCTION; BONE MARROW CELL; CELL ACTIVITY; COMBINATION CHEMOTHERAPY; DISEASE ASSOCIATION; DRUG EFFECT; DRUG MECHANISM; EDITORIAL; HEART INFARCTION SIZE; HEART LEFT VENTRICLE FUNCTION; MONOTHERAPY; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; ERYTHROPOIETIN; GRANULOCYTE COLONY-STIMULATING FACTOR; MYOCARDIAL INFARCTION; SWINE;

EID: 79958204674     PISSN: 09203206     EISSN: 15737241     Source Type: Journal    
DOI: 10.1007/s10557-010-6268-2     Document Type: Editorial

References (25)

1. Orlic D, Kajstura J, Chimenti S, Limana F, Jakoniuk I, Quaini F, et al. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci USA. 2001;98:10344-9. (Pubitemid 32803022)
2. Brunner S, Engelmann MG, Franz WM. Stem cell mobilisation for myocardial repair. Expert Opin Biol Ther. 2008;8:1675-90.
3. Abdel-Latif A, Bolli R, Zuba-Surma EK, Tleyjeh IM, Hornung CA, Dawn B. Granulocyte colony-stimulating factor therapy for cardiac repair after acute myocardial infarction: a systematic review and meta-analysis of randomized controlled trials. Am Heart J. 2008;156:216-26.e9.
4. Zohlnhofer D, Dibra A, Koppara T, de Waha A, Ripa RS, Kastrup J, et al. Stem cell mobilization by granulocyte colony-stimulating factor for myocardial recovery after acute myocardial infarction: a meta-analysis. J Am Coll Cardiol. 2008;51:1429-37. (Pubitemid 351470028)
5. Angeli FS, Smith C, Amabile N, Shapiro M, Bartlett L, Virmani R, et al. Granulocyte colony stimulating factor in myocardial infarction with low ejection fraction. Cytokine 2010;51:278-85.
6. Angeli FS, Amabile N, Burjonroppa S, Shapiro M, Bartlett L, Zhang Y, et al. Prolonged therapy with erythropoietin is safe and prevents deterioration of left ventricular systolic function in a porcinemodel of myocardial infarction. J Card Fail. 2010;16:579-89.
7. Angeli FS, Amabile N, Shapiro M, Mirsky R, Bartlett L, Zhang Y, et al. Cytokine combination therapy with erythropoietin and granulocyte colony stimulating factor in a porcine model of acute myocardial infarction. Cardiovasc Drugs Ther. 2010;24:this issue.
8. Calvillo L, Latini R, Kajstura J, Leri A, Anversa P, Ghezzi P, et al. Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling. Proc Natl Acad Sci USA. 2003;100:4802-6. (Pubitemid 36457809)
9. Ratajczak J, Majka M, Kijowski J, Baj M, Pan ZK, Marquez LA, et al. Biological significance of MAPK, AKT and JAK-STAT protein activation by various erythropoietic factors in normal human early erythroid cells. Br J Haematol. 2001;115:195-204. (Pubitemid 32995116)
10. Burger D, Lei M, Geoghegan-Morphet N, Lu X, Xenocostas A, Feng Q. Erythropoietin protects cardiomyocytes from apoptosis via up-regulation of endothelial nitric oxide synthase. Cardiovasc Res. 2006;72:51-9. (Pubitemid 44310637)
11. van der Meer P, Lipsic E, Henning RH, Boddeus K, van der Velden J, Voors AA, et al. Erythropoietin induces neovascularization and improves cardiac function in rats with heart failure after myocardial infarction. J Am Coll Cardiol. 2005;46:125-33. (Pubitemid 40905140)
12. Toma C, Letts DP, Tanabe M, Gorcsan 3rd J, Counihan PJ. Positive effect of darbepoetin on peri-infarction remodeling in a porcine model of myocardial ischemia-reperfusion. J Mol Cell Cardiol. 2007;43:130-6. (Pubitemid 47069386)
13. Westenbrink BD, Lipsic E, van der Meer P, van der Harst P, Oeseburg H, Du Marchie Sarvaas GJ, et al. Erythropoietin improves cardiac function through endothelial progenitor cell and vascular endothelial growth factor mediated neovascularization. Eur Heart J. 2007;28:2018-27. (Pubitemid 47579534)
14. Iwanaga K, Takano H, Ohtsuka M, Hasegawa H, Zou Y, Qin Y, et al. Effects of G-CSF on cardiac remodeling after acute myocardial infarction in swine. BiochemBiophys Res Commun. 2004;325:1353-9. (Pubitemid 39535912)
15. Dawn B, Guo Y, Rezazadeh A, Huang Y, Stein AB, Hunt G, et al. Postinfarct cytokine therapy regenerates cardiac tissue and improves left ventricular function. Circ Res. 2006;98:1098-105.
16. Demetri GD, Griffin JD. Granulocyte colony-stimulating factor and its receptor. Blood 1991;78:2791-808.
17. Harada M, Qin Y, Takano H, Minamino T, Zou Y, Toko H, et al. G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes. Nat Med. 2005;11:305-11. (Pubitemid 40460559)
18. Ueda K, Takano H, Hasegawa H, Niitsuma Y, Qin Y, Ohtsuka M, et al. Granulocyte colony stimulating factor directly inhibitsmyocardial ischemia-reperfusion injury through Akt-endothelial NO synthase pathway. Arterioscler Thromb Vasc Biol. 2006;26:e108-13.
19. Werneck-de-Castro JP, Costa ESRH, de Oliveira PF, Pinho- Ribeiro V, Mello DB, Pecanha R, et al. G-CSF does not improve systolic function in a rat model of acute myocardial infarction. Basic Res Cardiol. 2006;101:494-501. (Pubitemid 44637865)
20. Ripa RS, Jorgensen E,Wang Y, Thune JJ, Nilsson JC, Sondergaard L, et al. Stem cell mobilization induced by subcutaneous granulocytecolony stimulating factor to improve cardiac regeneration after acute ST-elevation myocardial infarction: result of the double-blind, randomized, placebo-controlled stem cells in myocardial infarction (STEMMI) trial. Circulation 2006;113:1983-92.
21. Zohlnhofer D, Ott I, Mehilli J, Schomig K, Michalk F, Ibrahim T, et al. Stem cell mobilization by granulocyte colony-stimulating factor in patients with acute myocardial infarction: a randomized controlled trial. JAMA 2006;295:1003-10.
22. Lee SS, Naqvi TZ, Forrester J, Cattley R, Shah A, Frantzen M, et al. The effect of granulocyte colony stimulating factor on regional and global myocardial function in the porcine infarct model. Int J Cardiol. 2007;116:225-30. (Pubitemid 46241483)
23. Sato T, Suzuki H, Kusuyama T, Omori Y, Soda T, Tsunoda F, et al. G-CSF after myocardial infarction accelerates angiogenesis and reduces fibrosis in swine. Int J Cardiol. 2008;127:166-73. (Pubitemid 351787786)
24. Beohar N, Flaherty JD, Davidson CJ, Vidovich M, Singhal S, Rapp JA, et al. Granulocyte-colony stimulating factor administration after myocardial infarction in a porcine ischemia-reperfusion model: functional and pathological effects of dose timing. Catheter Cardiovasc Interv. 2007;69:257-66.
25. Binbrek AS, Rao NS, Al Khaja N, Assaqqaf J, Sobel BE. Erythropoietin to augment myocardial salvage induced by coronary thrombolysis in patients with ST segment elevation acute myocardial infarction. Am J Cardiol. 2009;104:1035-40.