G-CSF after myocardial infarction accelerates angiogenesis and reduces fibrosis in swine

International Journal of Cardiology

Volumn 127, Issue 2, 2008, Pages 166-173

  Sato, Takatoshi ^a   Suzuki, Hiroshi ^a   Kusuyama, Taro ^a   Omori, Yasutoshi ^a   Soda, Teruko ^a   Tsunoda, Fumiyoshi ^a   Shoji, Makoto ^a   Iso, Yoshitaka ^a   Koba, Shinji ^a   Geshi, Eiichi ^a   Katagiri, Takashi ^a   Kawachi, Keisuke ^b   Wakabayashi, Kohei ^b   Takeyama, Youichi ^b  

^a SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SHOWA UNIVERSITY FUJIGAOKA HOSPITAL   (Japan)

Author keywords

Angiogenesis; G CSF; Myocardial infarction; Remodeling

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 3; GRANULOCYTE COLONY STIMULATING FACTOR; MESSENGER RNA; PROTEIN ANTIBODY; SODIUM CHLORIDE; TRANSFORMING GROWTH FACTOR BETA; VON WILLEBRAND FACTOR;

ANGIOCARDIOGRAPHY; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; BALLOON OCCLUSION; CONTROLLED STUDY; CORONARY ARTERY OBSTRUCTION; CORONARY ARTERY THROMBOSIS; HEART EJECTION FRACTION; HEART INFARCTION; HEART MUSCLE FIBROSIS; HEART VENTRICLE ENDDIASTOLIC PRESSURE; IMMUNOHISTOCHEMISTRY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SWINE;

ANIMALS; BALLOON OCCLUSION; BIOLOGICAL MARKERS; CORONARY ANGIOGRAPHY; FIBROSIS; GRANULOCYTE COLONY-STIMULATING FACTOR; IMMUNOENZYME TECHNIQUES; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION; NEOVASCULARIZATION, PHYSIOLOGIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SWINE;

EID: 44649163771     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2007.05.007     Document Type: Article

References (30)

1. Pfeffer M.A., and Braunwald E. Ventricular remodeling after myocardial infarction: experimental observations and clinical implications. Circulation 81 (1990) 1161-1172
2. St John Sutton M., Pfeffer M.A., Plappert T., et al. Quantitative two-dimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. The protective effects of captopril. Circulation 89 (1994) 68-75
3. Bolognese L., Neskovic A.N., Parodi G., et al. Left ventricular remodeling after primary coronary angioplasty. Circulation 106 (2002) 2351-2357
4. Orlic D., Kajstura J., Chimenti S., et al. Bone marrow cells regenerate infarcted myocardium. Nature 410 (2001) 701-705
5. Kajstura J., Rota M., Whang B., et al. Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion. Circ Res 96 (2005) 127-137
6. Wollert K.C., Meyer G.P., Lotz J., et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomized controlled clinical trial. Lancet 364 (2004) 141-148
7. Schaefer A., Meyer G.P., Fuchs M., et al. Impact of intracoronary bone marrow cell transfer on diastolic function in patients after myocardial infarction: results from the BOOST trial. Eur Heart J 27 (2006) 929-935
8. Schachinger V., Assmus B., Britten M., et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction: final one-year results of the TOPCARE-AMI Trial. J Am Coll Cardiol 44 (2004) 1690-1699
9. Laterveer L., Lindley I.J., Hamilton M.S., Willemze R., and Fibbe W.E. Interleukin-8 induces rapid mobilization of hematopoietic stem cells with radioprotective capacity and long-term myelolymphoid repopulating ability. Blood 85 (1995) 2269-2275
10. Lapidot T., and Petit I. Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells. Exp Hematol 30 (2002) 973-981
11. Orlic D., Kajstura J., Chimenti S., et al. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci U S A 98 (2001) 10344-10349
12. Bussolino F., Wang J.M., Defilippi P., et al. Granulocyte- and granulocyte-macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate. Nature 337 (1989) 471-473
13. Welte K., Bonilla M.A., Gillio A.P., et al. Recombinant human granulocyte colony-stimulating factor. Effects on hematopoiesis in normal and cyclophosphamide-treated primates. J Exp Med 165 (1987) 941-948
14. Ohtsuka M., Takano H., Zou Y., et al. Cytokine therapy prevents left ventricular remodeling and dysfunction after myocardial infarction through neovascularization. FASEB J 18 (2004) 851-853
15. Minatoguchi S., Takemura G., Chen X.H., et al. Acceleration of the healing process and myocardial regeneration may be important as a mechanism of improvement of cardiac function and remodeling by postinfarction granulocyte colony-stimulating factor treatment. Circulation 109 (2004) 2572-2580
16. Miki T., Miura T., Nishino Y., et al. Granulocyte colony stimulating factor/macrophage colony stimulating factor improves postinfarct ventricular function by suppression of border zone remodeling in rats. Clin Exp Pharmacol Physiol 31 (2004) 873-882
17. Sugano Y., Anzai T., Yoshikawa T., et al. Granulocyte colony-stimulating factor attenuates early ventricular expansion after experimental myocardial infarction. Cardiovasc Res 65 (2005) 446-456
18. Maekawa Y., Anzai T., Yoshikawa T., et al. Effect of granulocyte-macrophage colony-stimulating factor inducer on left ventricular remodeling after acute myocardial infarction. J Am Coll Cardiol 44 (2004) 1510-1520
19. Kang H.J., Kim H.S., Zhang S.Y., et al. Effects of intracoronary infusion of peripheral blood stem-cells mobilized with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: the MAGIC cell randomized clinical trial. Lancet 363 (2004) 751-756
20. Ince H., Petzsch M., Kleine H.D., et al. Preservation from left ventricular remodeling by front-integrated revascularization and stem cell liberation in evolving acute myocardial infarction by use of granulocyte-colony-stimulating factor (FIRSTLINE-AMI). Circulation 112 (2005) 3097-3106
21. Valgimigli M., Rigolin G.M., Cittanti C., et al. Use of granulocyte-colony stimulating factor during acute myocardial infarction to enhance bone marrow stem cell mobilization in humans: clinical and angiographic safety profile. Eur Heart J 26 (2005) 1838-1845
22. Hill J.M., Syed M.A., Arai A.E., et al. Outcomes and risks of granulocyte colony-stimulating factor in patients with coronary artery disease. J Am Coll Cardiol 46 (2005) 1643-1648
23. Ripa R.S., Jorgensen E., Wang Y., et al. Stem cell mobilization induced by subcutaneous granulocyte-colony stimulating factor to improve cardiac regeneration after acute ST-elevation myocardial infarction: result of the double-blind, randomized, placebo-controlled stem cells in myocardial infarction (STEMMI) trial. Circulation 113 (2006) 1983-1992
24. Zohlnhofer D., Ott I., Mehilli J., et al. Stem cell mobilization by granulocyte colony-stimulating factor in patients with acute myocardial infarction: a randomized controlled trial. JAMA 295 (2006) 1003-1010
25. Iwanaga K., Takano H., Ohtsuka M., et al. Effect of G-CSF on cardiac remodeling after acute myocardial infarction in swine. Biochem Biophys Res Commun 325 (2004) 1353-1359
26. Hasegawa H., Takano H., Iwanaga K., et al. Cardioprotective effects of granulocyte colony-stimulating factor in swine with chronic myocardial ischemia. J Am Coll Cardiol 47 (2006) 842-849
27. Wang J.F., Olson M.E., Reno C.R., Kulyk W., Wright J.B., and Hart D.A. Molecular and cell biology of skin wound healing in a pig model. Connect Tissue Res 41 (2000) 195-211
28. Harada M., Qin Y., Takano H., et al. G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes. Nat Med 11 (2005) 305-311
29. Kocher A.A., Schuster M.D., Szabolcs M.J., et al. Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med 7 (2001) 430-436
30. Schächinger V., Erbs S., and Elsässer A. Intracoronary bone marrow-derived pogenitor cells in acute myocardial infarction. N Engl J Med 355 (2006) 1210-1221