Differential kinetics of α-[11C]methyl-L-tryptophan on PET in low-grade brain tumors

Journal of Neuro-Oncology

Volumn 102, Issue 3, 2011, Pages 409-415

  Juhász, Csaba ^a,b   Muzik, Otto ^a   Chugani, Diane C ^a   Chugani, Harry T ^a   Sood, Sandeep ^a   Chakraborty, Pulak K ^a   Barger, Geoffrey R ^a,b   Mittal, Sandeep ^a,b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KARMANOS CANCER INSTITUTE   (United States)

Author keywords

Astrocytoma; Gliomas; Low grade; Metabolism; Positron emission tomography; Tryptophan

Indexed keywords

CARBON ALPHA METHYLTRYPTOPHAN C11; FLUORODEOXYGLUCOSE F 18; GADOLINIUM; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AMINO ACID TRANSPORT; ARTICLE; ASTROCYTOMA; CANCER GRADING; CHILD; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DISTRIBUTION VOLUME; FEMALE; HUMAN; KINETICS; MALE; NEUROEPITHELIOMA; NUCLEAR MAGNETIC RESONANCE IMAGING; OLIGODENDROGLIOMA; POSITRON EMISSION TOMOGRAPHY; PRESCHOOL CHILD; SCHOOL CHILD; TERATOMA; TRYPTOPHAN METABOLISM; TUMOR DIFFERENTIATION; TUMOR RECURRENCE;

ADOLESCENT; ADULT; ANALYSIS OF VARIANCE; BRAIN MAPPING; BRAIN NEOPLASMS; CARBON RADIOISOTOPES; CHILD; CHILD, PRESCHOOL; FEMALE; GLIOMA; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY; TRYPTOPHAN;

EID: 79958197360     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-010-0327-1     Document Type: Article

References (36)

1. Diksic M, Nagahiro S, Sourkes TL, Yamamoto YL (1990) A new method to measure brain serotonin synthesis in vivo. I. Theory and basic data for a biological model. J Cereb Blood Flow Metab 10:1-12 (Pubitemid 20035849)
2. Muzik O, Chugani DC, Chakraborty P, Mangner T, Chugani HT (1997) Analysis of [C-11]alpha-methyl-tryptophan kinetics for the estimation of serotonin synthesis rate in vivo. J Cereb Blood Flow Metab 17:659-669 (Pubitemid 27306690)
3. Chugani DC, Muzik O (2000) Alpha[C-11]methyl-L-tryptophan PET maps brain serotonin synthesis and kynurenine pathway metabolism. J Cereb Blood Flow Metab 20:2-9 (Pubitemid 30019823)
4. Munn DH, Mellor AL (2007) Indoleamine 2,3-dioxygenase and tumor-induced tolerance. J Clin Invest 117:1147-1154 (Pubitemid 46718399)
5. Batista CEA, Juhász C, Muzik O, Kupsky WJ, Barger G, Chugani HT, Chugani HT, Mittal S, Sood S, Chakraborty PK, Chugani DC (2009) Imaging correlates of differential expression of indoleamine 2,3-dioxygenase in human brain tumors. Mol Imaging Biol 11:460-466
6. Chen W (2007) Clinical applications of PET in brain tumors. J Nucl Med 48:1468-1481
7. Mittal S, Szlaczky MC, Barger GR (2008) Low-grade gliomas in adults. Curr Treat Options Neurol 10:271-284
8. 11C]methyl-L-tryptophan in human brain tumors. J Cereb Blood Flow Metab 26:345-357
9. Atkinson M, Juhász C, Shah J, Guo X, Kupsky W, Fuerst D, Johnson R, Watson C (2008) Paradoxical imaging findings in cerebral gliomas. J Neurol Sci 269:180-183
10. Chugani DC, Muzik O, Chakraborty P, Mangner T, Chugani HT (1998) Human brain serotonin synthesis capacity measured in vivo with alpha-[C-11]methyl-L- tryptophan. Synapse 28:33-43 (Pubitemid 128770601)
11. Muzik O, Behrendt DB, Mangner TJ, Chugani HT (1994) Design of a pediatric protocol for quantitative brain FDG studies with PET not requiring invasive blood sampling. J NuclMed 35:104 [abstract]
12. Suhonen-Pulvi H, Ruotsalainen U, Kinnala A, Bergman J, Haaparanta M, Teräs M, Mäkelä P, Solin O, Wegelius U (1995) FDG-PET in early infancy: simplified quantification methods to measure cerebral glucose utilization. J Nucl Med 36:1249-1254
13. Gjedde A (1981) High- and low-affinity transport of D-glucose from blood to brain. J Neurochem 36:1463-1471
14. Patlak CS, Blasberg RG, Fenstermacher JD (1983) Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 3:1-7 (Pubitemid 13129630)
15. Juhász C, Chugani DC, Muzik O, Shah A, Asano E, Mangner T, Chakraborty PK, Sood S, Chugani HT (2003) Alpha-methyl-Ltryptophan PET detects epileptogenic cortex in children with intractable epilepsy. Neurology 60:960-968 (Pubitemid 36348928)
16. Pollack IF (1994) Brain tumors in children. N Engl J Med 331:1500-1507
17. Schomas DA, Laack NN, Rao RD, Meyer FB, Shaw EG, O'Neill BP, Giannini C, Brown PD (2009) Intracranial low-grade gliomas in adults: 30-year experience with long-term follow-up at Mayo Clinic. Neuro-Oncology 11:437-445
18. Vertosick FT Jr, Selker RG, Arena VC (1991) Survival of patients with well-differentiated astrocytomas diagnosed in the era of computed tomography. Neurosurgery 28:496-501
19. McCormack BM, Miller DC, Budzilovich GN, Voorhees GJ, Ransohoff J (1992) Treatment and survival of low-grade astrocytoma in adults - 1977-1988. Neurosurgery 31:636-642
20. Mason WP, Krol GS, DeAngelis LM (1996) Low-grade oligodendroglioma responds to chemotherapy. Neurology 46:203-207 (Pubitemid 26156130)
21. Olson JD, Riedel E, DeAngelis LM (2000) Long-term outcome of low-grade oligodendroglioma and mixed glioma. Neurology 54:1442-1448 (Pubitemid 30210463)
22. Kitange GJ, Smith JS, Jenkins RB (2001) Genetic alterations and chemotherapeutic response in human diffuse gliomas. Expert Rev Anticancer Ther 1:595-605 (Pubitemid 34679450)
23. Tozer DJ, Jäger HR, Danchaivijitr N, Benton CE, Tofts PS, Rees JH, Waldman AD (2007) Apparent diffusion coefficient histograms may predict low-grade glioma subtype. NMR Biomed 20:49-57 (Pubitemid 46332440)
24. Khayal IS, McKnight TR, McGue C, Vandenberg S, Lamborn KR, Chang SM, Cha S, Nelson SJ (2009) Apparent diffusion coefficient and fractional anisotropy of newly diagnosed grade II gliomas. NMR Biomed 22:449-455
25. Khayal IS, Nelson SJ (2009) Characterization of low-grade gliomas using RGB color maps derived from ADC histograms. J Magn Reson Imaging 30:209-213
26. 11C]-L-Methionine positron emission tomography in the management of children and young adults with brain tumors. J Neurooncol 96:231-239
27. 11C-Methionine (MET) and 18F-fluorothymidine (FLT) PET in patients with newly diagnosed glioma. Eur J Nucl Med Mol Imaging 35:2009-2017
28. 11C-choline positron-emission tomography. AJNR Am J Neuroradiol 29:1176-1182
29. 11C-methionine uptake in low-grade gliomas and correlation with proliferative activity. AJNR Am J Neuroradiol 29:1867-1871
30. 11C]methionine PET in the diagnosis of dysembryoplastic neuroepithelial tumor with temporal lobe epilepsy. Epilepsia 45:41-45
31. 11C]-Methionine PET: dysembryoplastic neuroepithelial tumours compared with other epileptogenic brain neoplasms. J Neurol Neurosurg Psychiatry 76:1686-1692
32. 11C-methionine (MET) uptake with L-type amino acid transporter 1 in human gliomas. J Neurooncol. doi:10.1007/s11060-010-0117- 9
33. Astigiano S, Morandi B, Costa R, Mastracci L, D'Agostino A, Ratto GB, Melioli G, Frumento G (2005) Eosinophil granulocytes account for indoleamine 2,3-dioxygenase-mediated immune escape in human non-small cell lung cancer. Neoplasia 7:390-396 (Pubitemid 40664228)
34. Okamoto A, Nikaido T, Ochiai K, Takakura S, Saito M, Aoki Y, Ishii N, Yanaihara N, Yamada K, Takikawa O, Kawaguchi R, Isonishi S, Tanaka T, Urashima M (2005) Indoleamine 2,3-dioxygenase serves as a marker of poor prognosis in gene expression profiles of serous ovarian cancer cells. Clin Cancer Res 11:6030-6039 (Pubitemid 41170335)
35. Brandacher G, Perathoner A, Ladurner R, Schneeberger S, Obrist P, Winkler C, Werner ER, Werner-Felmayer G, Weiss HG, Göbel G, Margreiter R, Königsrainer A, Fuchs D, Amberger A (2006) Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells. Clin Cancer Res 12:1144-1151 (Pubitemid 43342502)
36. Liu X, Newton RC, Friedman SM, Scherle PA (2009) Indoleamine 2,3-dioxygenase, an emerging target for anti-cancer therapy. Curr Cancer Drug Targets 9:938-952