-
1
-
-
27244440858
-
Construction of a bispecific antisense oligonucleotide containing multiple binding sites for the treatment of hormone insensitive prostate tumors
-
Rubenstein M, Tsui P, Guinan P. Construction of a bispecific antisense oligonucleotide containing multiple binding sites for the treatment of hormone insensitive prostate tumors. Med Hypotheses. 2005;65:905-907.
-
(2005)
Med Hypotheses
, vol.65
, pp. 905-907
-
-
Rubenstein, M.1
Tsui, P.2
Guinan, P.3
-
2
-
-
33845363458
-
Bispecific antisense oligonucleotides with multiple binding sites for the treatment of prostate tumors and their applicability to combination therapy
-
Rubenstein M, Tsui P, Guinan P. Bispecific antisense oligonucleotides with multiple binding sites for the treatment of prostate tumors and their applicability to combination therapy. Methods Find Exp Clin Pharmacol. 2006;28:515-518.
-
(2006)
Methods Find Exp Clin Pharmacol
, vol.28
, pp. 515-518
-
-
Rubenstein, M.1
Tsui, P.2
Guinan, P.3
-
3
-
-
36249025698
-
Combination chemotherapy employing bispecific antisense oligonucleotides having binding sites directed against an autocrine regulated growth pathway and BCL-2 for the treatment of prostate cancer
-
Rubenstein M, Tsui P, Guinan P. Combination chemotherapy employing bispecific antisense oligonucleotides having binding sites directed against an autocrine regulated growth pathway and BCL-2 for the treatment of prostate cancer. Med Oncol. 2007;24:372-378.
-
(2007)
Med Oncol
, vol.24
, pp. 372-378
-
-
Rubenstein, M.1
Tsui, P.2
Guinan, P.3
-
4
-
-
67651034609
-
Multigene targeting of signal transduction pathways for the treatment of breast and prostate tumors. Comparison between combination therapies employing bispecific oligonucleotides with either Rapamycin or Paclitaxel
-
Rubenstein M, Tsui P, Guinan P. Multigene targeting of signal transduction pathways for the treatment of breast and prostate tumors. Comparison between combination therapies employing bispecific oligonucleotides with either Rapamycin or Paclitaxel. Med Oncol. 2009;26: 124-130.
-
(2009)
Med Oncol
, vol.26
, pp. 124-130
-
-
Rubenstein, M.1
Tsui, P.2
Guinan, P.3
-
5
-
-
36248978135
-
Bispecific antisense oligonucleotides having binding sites directed against an autocrine regulated growth pathway and BCL-2 for the treatment of prostate tumors
-
Rubenstein M, Tsui P, Guinan P. Bispecific antisense oligonucleotides having binding sites directed against an autocrine regulated growth pathway and BCL-2 for the treatment of prostate tumors. Med Oncol. 2007;24:189-196.
-
(2007)
Med Oncol
, vol.24
, pp. 189-196
-
-
Rubenstein, M.1
Tsui, P.2
Guinan, P.3
-
6
-
-
33644602377
-
Novel bispecific antisense oligonucleotides inhibiting both BCL-2 and Bcl-xL expression induce apoptosis and enhance chemosensitivity in human androgen-independent prostate cancer cells
-
Abstract #2930 (online)
-
Yamanaka K, Miyake H, Zangemeister-wittke U, Jansen B, Gleave M. Novel bispecific antisense oligonucleotides inhibiting both BCL-2 and Bcl-xL expression induce apoptosis and enhance chemosensitivity in human androgen-independent prostate cancer cells. Proc Am Assoc Cancer Res. 2004;45:Abstract #2930 (online).
-
(2004)
Proc Am Assoc Cancer Res
, vol.45
-
-
Yamanaka, K.1
Miyake, H.2
Zangemeister-wittke, U.3
Jansen, B.4
Gleave, M.5
-
7
-
-
77955866744
-
Insulin-like growth factor-binding protein-5 (IGFBP5) supports prostate cancer cell proliferation
-
Takahara K, Muramaki M, Li D, Cox ME, Gleave ME. Insulin-like growth factor-binding protein-5 (IGFBP5) supports prostate cancer cell proliferation. J Urol. 2009;181:184a.
-
(2009)
J Urol
, vol.181
-
-
Takahara, K.1
Muramaki, M.2
Li, D.3
Cox, M.E.4
Gleave, M.E.5
-
8
-
-
8844281771
-
Inhibitory effect of antisense oligonucleotides targeting epidermal growth factor receptor may not be related to changes in mRNA levels in human prostate carcinoma cells
-
Rubenstein M, Mirochnik Y, Bremer E, George D, Freilich L, Guinan P. Inhibitory effect of antisense oligonucleotides targeting epidermal growth factor receptor may not be related to changes in mRNA levels in human prostate carcinoma cells. Proc Am Assoc Cancer Res. 2002;43:590a.
-
(2002)
Proc Am Assoc Cancer Res
, vol.43
-
-
Rubenstein, M.1
Mirochnik, Y.2
Bremer, E.3
George, D.4
Freilich, L.5
Guinan, P.6
-
9
-
-
8844258791
-
A review of antisense oligonucleotides in the treatment of human disease
-
Rubenstein M, Tsui P, Guinan P. A review of antisense oligonucleotides in the treatment of human disease. Drugs Future. 2004;29:893-909.
-
(2004)
Drugs Future
, vol.29
, pp. 893-909
-
-
Rubenstein, M.1
Tsui, P.2
Guinan, P.3
-
10
-
-
48049088387
-
Treatment of MCF-7 breast cancer cells employing mono- and bispecific antisense oligonucleotides having binding specificity toward proteins associated with autocrine regulated growth and BCL-2
-
Rubenstein M, Tsui P, Guinan P. Treatment of MCF-7 breast cancer cells employing mono- and bispecific antisense oligonucleotides having binding specificity toward proteins associated with autocrine regulated growth and BCL-2. Med Oncol. 2008;25:182-186.
-
(2008)
Med Oncol
, vol.25
, pp. 182-186
-
-
Rubenstein, M.1
Tsui, P.2
Guinan, P.3
-
11
-
-
0035914390
-
PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of BCL-2 expression
-
Huang H, Cheville JC, Pan Y, Roche PC, Schmidt LJ, Tindall DJ. PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of BCL-2 expression. J Biol Chem. 2001;276:38830-38836.
-
(2001)
J Biol Chem
, vol.276
, pp. 38830-38836
-
-
Huang, H.1
Cheville, J.C.2
Pan, Y.3
Roche, P.C.4
Schmidt, L.J.5
Tindall, D.J.6
-
12
-
-
33847668419
-
Increased bax.BCL-2 ratio up-regulates caspase-3 and increases apoptosis in the thymus of patients with myasthenia gravis
-
Salakou S, Kardamakis D, Tsamandas AC, et al. Increased bax.BCL-2 ratio up-regulates caspase-3 and increases apoptosis in the thymus of patients with myasthenia gravis. In Vivo. 2007;21:123-132.
-
(2007)
In Vivo
, vol.21
, pp. 123-132
-
-
Salakou, S.1
Kardamakis, D.2
Tsamandas, A.C.3
-
13
-
-
0032892149
-
An elevated bax/ BCL-2 ratio corresponds with the onset of prostate epithelial cell apoptosis
-
Perlman H, Zhang X, Chen MW, Walsh K, Buttyan R. An elevated bax/ BCL-2 ratio corresponds with the onset of prostate epithelial cell apoptosis. Cell Death Differ. 1999;6:48-54.
-
(1999)
Cell Death Differ
, vol.6
, pp. 48-54
-
-
Perlman, H.1
Zhang, X.2
Chen, M.W.3
Walsh, K.4
Buttyan, R.5
-
14
-
-
28144459799
-
Combination BCL-2 antisense and radiation therapy for nasopharyngeal cancer
-
Yip KW, Mocanu JD, Au PY, et al. Combination BCL-2 antisense and radiation therapy for nasopharyngeal cancer. Clin Cancer Res. 2005;11: 8131-8144.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8131-8144
-
-
Yip, K.W.1
Mocanu, J.D.2
Au, P.Y.3
-
15
-
-
28744451267
-
Antisense BCL-2 sensitizes prostate cancer cells to radiation
-
Mu Z, Hachem P, Pollack A. Antisense BCL-2 sensitizes prostate cancer cells to radiation. Prostate. 2005;65:331-340.
-
(2005)
Prostate
, vol.65
, pp. 331-340
-
-
Mu, Z.1
Hachem, P.2
Pollack, A.3
-
16
-
-
33748968813
-
Synthesis of branched antisense oligonucleotides having multiple specificities. Treatment of hormone insensitive prostate cancer
-
Rubenstein M, Anderson KM, Tsui P, Guinan P. Synthesis of branched antisense oligonucleotides having multiple specificities. Treatment of hormone insensitive prostate cancer. Med Hypotheses. 2006;67:1375-1380.
-
(2006)
Med Hypotheses
, vol.67
, pp. 1375-1380
-
-
Rubenstein, M.1
Anderson, K.M.2
Tsui, P.3
Guinan, P.4
|