Bispecific antisense oligonucleotides having binding sites directed against an autocrine regulated growth pathway and bcl-2 for the treatment of prostate tumors
Antisense oligonucleotide intralesional therapy for human PC-3 prostate tumors carried in athymic nude mice
Rubenstein M, Mirochnik Y, Chou P, Guinan P. Antisense oligonucleotide intralesional therapy for human PC-3 prostate tumors carried in athymic nude mice. J Surg Oncol 1996;62:194-200.
Novel bispecific antisense oligonucleotides inhibiting both Bcl-2 and Bcl-xL expression induce apoptosis and enhance chemosensitivity in human androgen-independent prostate cancer cells
abstract
Yamanaka K, Miyake H, Zangemeister-wittke U, Jansen B, Gleave M. Novel bispecific antisense oligonucleotides inhibiting both Bcl-2 and Bcl-xL expression induce apoptosis and enhance chemosensitivity in human androgen-independent prostate cancer cells. Proc Am Assoc Cancer Res 2004;45:abstract #2930.
Construction of a bispecific antisense oligonucleotide containing multiple binding sites for the treatment of hormone insensitive prostate tumors
Rubenstein M, Tsui P, Guinan P. Construction of a bispecific antisense oligonucleotide containing multiple binding sites for the treatment of hormone insensitive prostate tumors. Med Hypotheses 2005;65:905-907.
Bispecific antisense oligonucleotides with multiple binding sites for the treatment of prostate tumors and their applicability to combination therapy
Rubenstein M, Tsui P, Guinan P. Bispecific antisense oligonucleotides with multiple binding sites for the treatment of prostate tumors and their applicability to combination therapy. Methods Find Clin Pharmacol 2006;28:1-4.
Synthesis of branched antisense oligonucleotides having multiple specificities: Treatment of hormone insensitive prostate cancer
Rubenstein M, Anderson KM, Tsui P, Guinan P. Synthesis of branched antisense oligonucleotides having multiple specificities: treatment of hormone insensitive prostate cancer. Med. Hypotheses 2006;67:1374-1379.
Synthesis of polymeric prodrug Polycefin based on biodegradable poly (malic acid) for drug delivery
Lee BS, et al. Synthesis of polymeric prodrug Polycefin based on biodegradable poly (malic acid) for drug delivery. Proc Am Assoc Cancer Res 2006;97:258a.
Progression to androgen independence is delayed by adjuvant treatment with antisense bcl-2 oligodeoxynucleotides after castration in the LNCaP prostate tumor model
Gleave M, et al. Progression to androgen independence is delayed by adjuvant treatment with antisense bcl-2 oligodeoxynucleotides after castration in the LNCaP prostate tumor model. Clin Cancer Res 1999;5:2891- 898.
Inhibition of Rous sarcoma virus replication and transformation by a specific deoxynucleotide
Zamecnik PC, Stephenson ML. Inhibition of Rous sarcoma virus replication and transformation by a specific deoxynucleotide. Proc Natl Acad Sci USA 1979;75:280-284.
Synergistic effects of combination therapy employing antisense oligonucleotides with traditional chemotherapeutics in the PC-3 prostate cancer model
Tsui P, Rubenstein M, Guinan P. Synergistic effects of combination therapy employing antisense oligonucleotides with traditional chemotherapeutics in the PC-3 prostate cancer model. Med Oncol 2004;21:339-348.
Inhibition of PC-3 prostate cancer cell growth in vitro using both antisense oligonucleotides and Taxol
Rubenstein M, Slobodskoy L, Mirochnik Y, Guinan P. Inhibition of PC-3 prostate cancer cell growth in vitro using both antisense oligonucleotides and Taxol. Med Oncol 2003;20:29-35.
Two constructed antibody derived delivery vehicles for targeting oligodeoxynucleotides to prostate tumors expressing prostate specific antigen
Mirochnik Y, Rubenstein M, Guinan P. Two constructed antibody derived delivery vehicles for targeting oligodeoxynucleotides to prostate tumors expressing prostate specific antigen. Drug Del 2004;11:161-167.