Effects of anandamide in migraine: Data from an animal model

Journal of Headache and Pain

Volumn 12, Issue 2, 2011, Pages 177-183

  Greco, Rosaria ^a   Mangione, Antonina Stefania ^a   Sandrini, Giorgio ^a   Maccarrone, Mauro ^c,d   Nappi, Giuseppe ^a,b   Tassorelli, Cristina ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^d UNIVERSITY OF TERAMO   (Italy)

Author keywords

AEA; Formalin test; Migraine; Nitroglycerin

Indexed keywords

ANANDAMIDE; CANNABINOID RECEPTOR; DRUG VEHICLE; ENDOCANNABINOID; FORMALDEHYDE; GLYCERYL TRINITRATE; PROTEIN FOS;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA POSTREMA; ARTICLE; CONTROLLED STUDY; HYPERALGESIA; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; MALE; MIGRAINE; NERVE CONDUCTION; NOCICEPTION; NONHUMAN; PARABRACHIAL NUCLEUS; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; RAT; SPRAGUE DAWLEY RAT; SUPRAOPTIC NUCLEUS; TRIGEMINAL NUCLEUS;

ANALGESICS; ANIMALS; ARACHIDONIC ACIDS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; DRUG INTERACTIONS; ENDOCANNABINOIDS; MALE; MIGRAINE DISORDERS; NITROGLYCERIN; PAIN MEASUREMENT; POLYUNSATURATED ALKAMIDES; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS; TREATMENT OUTCOME; VASODILATOR AGENTS;

EID: 79958177252     PISSN: 11292369     EISSN: 11292377     Source Type: Journal    
DOI: 10.1007/s10194-010-0274-4     Document Type: Article

References (37)

1. Di Marzo V, Petrosino S (2007) Endocannabinoids and the regulation of their levels in health and disease. Curr Opin Lipidol 18:129-140 (Pubitemid 46412082)
2. Centonze D, Rossi S, Finazzi-Agrò A, Bernardi G, Maccarrone M (2007) The (endo)cannabinoid system in multiple sclerosis and amyotrophic lateral sclerosis. Int Rev Neurobiol 82:171-186
3. Pertwee RG (2001) Cannabinoid receptors and pain. Prog Neurobiol 63:569-611
4. Hunt SP, Pini A, Evan G (1987) Induction of c-fos-like protein in spinal cord neurons following sensory stimulation. Nature 328:632-634 (Pubitemid 17103967)
5. Nackley AG, Suplita RL, Hohmann AG (2003) A peripheral cannabinoid mechanism suppresses spinal fos protein expression and pain behavior in a rat model of inflammation. Neuroscience 117:659-670 (Pubitemid 36263159)
6. Tsou K, Brown S, Sanudo-Pena MC, Mackie K, Walker JM (1998) Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience 83:393-411 (Pubitemid 28062631)
7. Myers DE (1999) Potential neurogenic and vascular roles of nitric oxide in migraine headache and aura. Headache 39(2):118-124
8. Uddman R, Edvinsson L, Ekman R, Kingman T, McCulloch J (1985) Innervation of the feline cerebral vasculature by nerve fibers containing calcitonin gene-related peptide: trigeminal origin and co-existence with substance P. Neurosci Lett 62(1): 131-136 (Pubitemid 16205735)
9. Russo EB (2004) Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? Neuro Endocrinol Lett 25:31-39
10. Akerman S, Kaube H, Goadsby PJ (2004) Anandamide is able to inhibit trigeminal neurons using an in vivo model of trigeminovascular-mediated nociception. J Pharmacol Exp Ther 309(1):56-63 (Pubitemid 38393114)
11. Sarchielli P, Alberti A, Floridi A, Gallai V (2001) Levels of nerve growth factor in cerebrospinal fluid of chronic daily headache patients. Neurology 57:132-134 (Pubitemid 32634864)
12. Sarchielli P, Alberti A, Gallai B, Coppola F, Baldi A, Gallai V (2002) Brain-derived neurotrophic factor in cerebrospinal fluid of patients with chronic daily headache: relationship with nerve growth factor and glutamate levels. J Headache Pain 3:129-135 (Pubitemid 36054543)
13. Buzzi MG, Tassorelli C, Nappi G (2003) Peripheral and central activation of trigeminal pain pathways in migraine: data from experimental animal models. Cephalalgia 23:1-4 (Pubitemid 36583715)
14. Tassorelli C, Greco R, Wang D, Morelli G, Nappi G (2003) Nitroglycerin induces hyperalgesia in rats: a time-course study. Eur. J. Pharm. 464:159-162 (Pubitemid 36293735)
15. Tassorelli C, Greco R, Wang D, Sandrini G, Nappi G (2006) Prostaglandins, glutamate and nitric oxide synthase mediate nitroglycerin-induced hyperalgesia in the formalin test. Eur J Pharmacol 534:103-107 (Pubitemid 43384189)
16. Greco R, Gasperi V, Sandrini G, Bagetta G, Nappi G, Maccarrone M, Tassorelli C (2010) Alterations of the endocannabinoidsystem in an animal model of migraine: evaluation in cerebral areas of rat. Cephalalgia 30(3):296-302
17. Tjolsen A, Berge OG, Hunskaar S, Rosland JH, Hole K (1992) The formalin test: an evaluation of the method. Pain 51:5-17
18. Jaggar SI, Hasnie FS, Sellaturay S, Rice AS (1998) The antihyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain. Pain 76:189-199 (Pubitemid 28304956)
19. Costa B, Vailati S, Colleon M (1999) SR 141716A, a cannabinoid receptor antagonist, reverses the behavioural effectsof anandamide-treated rats. Behav Pharmacol 10:327-331 (Pubitemid 29301268)
20. Tassorelli C, Joseph SA, Buzzi G, Nappi G (1999) The effect on the central nervous system of nitroglycerin - putative mechanisms and mediators. Prog Neurobiol 57:606-624
21. Tassorelli C, Joseph SA, Nappi G (1997) Neurochemical mechanisms of nitroglycerin-induced neuronal activation. Neuropharmacology 10:1417-1424
22. Tassorelli C, Greco R, Morazzoni P, Riva A, Sandrini G, Nappi G (2005) Parthenolide is the component of Tanacetum parthenium that inhibits nitroglycerin-induced Fos activation: studies in an animal model of migraine. Cephalalgia 25:612-621 (Pubitemid 41026027)
23. Moldrich G, Wenger T (2000) Localization of the CB1 cannabinoid receptor in the rat brain. An immunohistochemical study. Peptides 21(11):1735-1742
24. Mailleux P, Vanderhaeghen JJ (1992) Distribution of neuronal cannabinoid receptor in the adult rat brain: A comparative receptor binding radioautography and in situ hybridization histochemistry. Neuroscience 48:655-668
25. Smith PB, Compton DR, Welch SP, Razdan RK, Mechoulam R, Martin BR (1994) The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice. J Pharmacol Exp Ther 270:219-227 (Pubitemid 24229631)
26. Welch SP, Dunlow LD, Patrick GS, Razdan RK (1995) Characterisation of anandamide- and fluoroanandamide-induced antinociception and cross tolerance to delta-9-THC after intrathecal administration to mice: blockade of delta-9-THC-induced antinociception. J Pharmacol Exp Ther 273:1235-1244
27. Lichtman AH, Martin BR (1991) Spinal and supraspinal components of cannabinoid-induced antinociception. J Pharmacol Exp Ther 258:517-523
28. Martin WJ, Patrick SL, Coffin PO, Tsou K, Walker JM (1995) An examination of the central sites of action of cannabinoid-induced antinociception in the rat. Life Sci 56:2103-2109
29. Greco R, Tassorelli C, Sandrini G, Di Bella P, Buscone S, Nappi G (2008) Role of calcitonin gene-related peptide and substance P in different models of pain. Cephalalgia 28(2):114-126
30. Pardutz A, Multon S, Malgrange B, Parducz A, Vecsei L, Schoenen J (2002) Effect of systemic nitroglycerin on CGRP and 5-HT afferents to rat caudal spinal trigeminal nucleus and its modulation by estrogen. Eur J Neurosci 15(11):1803-1809 (Pubitemid 35471905)
31. Di Marzo V, Deutsch DG (1998) Biochemistry of the endogenous ligands of cannabinoid receptor. Neurobiol Dis 5:386-404 (Pubitemid 29075840)
32. Malan TP Jr, Ibrahim MM, Deng H, Liu Q, Mata HP, Vanderah T, Porreca F, Makriyannis A (2001) CB2 cannabinoid receptor-mediated peripheral antinociception. Pain 93:239-245 (Pubitemid 32763181)
33. Van Sickle MD, Duncan M, Kingsley PJ, Mouihate A, Urbani P, Mackie K, Stella N, Makriyannis A, Piomelli D, Davison JS, Marnett LJ, Di Marzo V, Pittman QJ, Patel KD, Sharkey KA (2005) Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science 310(5746):329-332 (Pubitemid 41457202)
34. Patel NA, Moldow RL, Patel JA, Wu G, Chang SL (1998) Arachidonylethanolamide (AEA) activation of FOS proto-oncogene protein immunoreactivity in the rat brain. Brain Res 797(2):225-233 (Pubitemid 28332735)
35. McGregor IS, Arnold JC, Weber MF, Topple AN, Hunt GE (1998) A comparison of delta 9-THC and anandamide induced c-fos expression in the rat forebrain. Brain Res 802(1-2):19-26 (Pubitemid 28392153)
36. Richardson JD, Aanonsen L, Hargreaves KM (1998) Antihyperalgesic effects of spinal cannabinoids. Eur J Pharmacol 345(2):145-153 (Pubitemid 28212345)
37. Van Sickle MD, Oland LD, Mackie K, Davison JS, Sharkey KA (2003) Delta9-tetrahydrocannabinol selectively acts on CB1 receptors in specific regions of dorsal vagal complex to inhibit emesis in ferrets. Am J Physiol Gastrointest Liver Physiol 285(3):G566-G576 (Pubitemid 37021816)